STAFF SCIENTIST

STAFF SCIENTIST

• New Orleans, Louisiana, United States
• Other Academic
• Medicine

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Closing date: December 25, 2026

Title: STAFF SCIENTIST

Employee Type: Other Academic

Department: Center of excellence-Cancer

Campus Location: CANCER CENTER/SETON BLDG./2025

Job Summary/Basic Functions

The Staff Scientist Staff Scientist will investigate the critical intersection of host metabolic health and tumor biology. Specifically, they will study how obesity-induced systemic changes drive metabolic reprogramming and epigenetic remodeling in prostate cancer. Research will place special emphasis on how these dual mechanisms converge to promote therapeutic resistance and lineage plasticity, with the goal of identifying novel therapeutic targets.

The Staff Scientist will lead projects investigating how obesity alters the prostate tumor microenvironment, focusing on crosstalk among adipocyte-derived factors, tumor metabolism, and epigenetic states (e.g., histone modifications, DNA methylation). Uncover pathways that promote survival and lineage plasticity under therapeutic stress, including androgen deprivation therapy (ADT) and next-generation anti-androgens. They will be responsible for Multi-Omic Integration: Design and execute high-throughput multi-omic workflows that integrate data from RNA-seq, ChIP-seq, ATAC-seq, and metabolomics. The Staff Scientist will also apply CRISPR-Cas9 genetic screens and targeted gene editing to functionally validate candidates that drive drug resistance, conduct independent computational analyses and develop pipelines to interpret complex multi-omic data and, help with the preparation of high-impact manuscripts and actively pursue extramural funding.

Minimum Qualifications

Required Education: PhD

Required Field of Study: Basic Science, Health Science, Bioinformatics, or related field

Number of years required to perform the job: 0 - 2 years

Type of experience required to perform the job: Experience in a research environment

Substitution: MD or DDS are also acceptable

Comprehensive benefits are available to eligible employees and their dependents including health, life, dental, and vision insurance; flexible spending accounts; retirement plans; generous annual and sick leave; 14 paid holidays per year; and an employee health primary care clinic. See following link for more details on our benefits offerings: LSUHSC, New Orleans - Benefits

Other employee benefits include a full-service credit union, wellness benefits featuring complimentary fitness center membership for employees and their spouses, employee assistance program, campus assistance program, and pet insurance option. More information about these benefits can be found on this webpage: Additional Benefits