Senior Machine Learning Engineer, Agentic Science/Generative Models, AI for Biology & Translation (AIBT) Genentech IncSenior Machine Learning Engineer, Agentic Science/Generative Models, AI for Biology & Translation (AIBT)South San Francisco, CA$168,100–$312,300 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Roche's Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact.
Principal Statistical Methodology Data Scientist Genentech IncPrincipal Statistical Methodology Data ScientistSouth San Francisco, CA$185,200–$343,900 / yearStatistical Methodology Data Scientists collaborate closely with project teams, biostatisticians, and cross-functional stakeholders to identify methodological needs, prototype solutions (e.g., estimand frameworks, trial simulations, covariate adjustment strategies), and support scalable adoption through training, templates, and open source software/tools. The Opportunity: As a Principal Statistical Methodology Data Scientist you will: You serve as a methodological thought partner to study teams, providing expert guidance on complex design and analysis across programs.
Senior Director, Workplace Strategy & Design Studio Genentech IncSenior Director, Workplace Strategy & Design StudioSouth San Francisco, CA$190,900–$354,500 / yearProvide strategic direction to the Design Studio responsible for interior architecture and interior design across offices, labs, and technical spaces; lab and technical design, including lab planning, lab automation, and robotics; and furniture and workplace configuration strategies. 15+ years of progressive business experience in workplace strategy, real estate, interior architecture/design, and/or engineering, with extensive workplace strategy and change management experience, and significant exposure to campus occupancy planning and complex multi‑site environments.
Executive Director, Workplace Delivery Genentech IncExecutive Director, Workplace DeliverySouth San Francisco, CA$241,800–$449,000 / yearYou'll have primary accountability for setting direction and ensuring executive-level oversight across real estate and workplace strategy, portfolio and asset management, real estate transaction, strategic campus and master planning, workplace experience strategy, design, architecture, and placemaking as well as integrated project and program delivery. Additionally, you'll define and champion a long-term workplace vision for the South San Francisco campus, ensuring alignment with corporate and Roche Group strategies and act as a strategic connector between Workplace Delivery and leadership, providing a unified, client-focused engagement model across all business units.
Senior Director, Business Operations & Portfolio Controls Genentech IncSenior Director, Business Operations & Portfolio ControlsSouth San Francisco, CA$189,400–$351,700 / yearBuild and lead integrated Business Operations and Portfolio Controls teams, bringing together subject matter experts in project controls, estimating, scheduling, capital governance, safety, and business process design. Proven track record establishing and leading project controls, portfolio management, and/or business operations functions for large portfolios and major capital programs.
Corporate Counsel, Global Legal R&D Genentech IncCorporate Counsel, Global Legal R&DSouth San Francisco, CA$181,800–$337,600 / yearKey responsibilities of this role include the following: Proactively providing strategic business and legal advice and education related to the following: FDA laws, regulations and guidance and other laws and regulations governing the research and development of biotech/pharmaceutical products; Early research through interventional trials, including drug, biologics, advanced therapy medicinal product, software as medical device, and biomarker and omics research, Use of AI in research and development activities. As a member of the Roche Global Legal Pharma's R&D Legal team, this Corporate Counsel role will support global business functions within Roche's Pharmaceutical division, such as Research and Early Development, Clinical Operations, Global Product Development, and Medical Affairs, by providing strategic legal advice to advance the company's pipeline; this pipeline includes drug, device, digital and integrated solutions.
Senior Director, Real Estate Strategy & Portfolio Planning Genentech IncSenior Director, Real Estate Strategy & Portfolio PlanningSouth San Francisco, CA$209,000–$388,100 / yearLead the end‑to‑end real estate and portfolio strategy for the South San Francisco campus and related sites, including real estate strategy and scenario planning; asset acquisition, management and divestment; and real estate transactions and lease administration. In this pivotal role, you will be accountable for real estate and portfolio strategy; campus and master planning; asset acquisition/divestment and real estate transactions; space management, forecasting, and utilization analytics; and real estate business systems, data, and analytics.
NewPatient Experience Business Designer GenentechPatient Experience Business DesignerPatient Strategy aims to create a holistic, cross-functional approach to deliver a best-in-class patient experience that aligns with the portfolio, technology tools, and consumer-driven patient expectations in a rapidly evolving business landscape. In doing so, you will bridge the gap between creative design and business execution to maximize patient impact by transforming complex healthcare navigation into frictionless, patient-first solutions that ensure every innovation translates into tangible value for those we serve.
Systems Specialist II Genentech IncSystems Specialist IISouth San Francisco, CA$91,900–$170,700 / yearWe explore the structural and functional properties of therapeutic targets and their interactions with diverse ligands both in vitro and in situ to discover and explain biological phenomena relevant to our drug discovery efforts. We collaborate with scientists throughout the company to advance both traditional small molecule and protein-based drug discovery, as well as to pursue basic research questions regarding protein structure and function.
NewSenior Medical Science Liaison, Neuroimmunology (Northern California) GenentechSenior Medical Science Liaison, Neuroimmunology (Northern California)San Francisco, CaliforniaIn addition, TA MSLs may be responsible for covering multiple medicines, as well as engaging in broad scientific discussions about patient outcomes and total cost of care, resulting in rich customer insights shared with key stakeholders across the organization. The Therapeutic Area Medical Science Liaison (TA MSL) is a credible scientific partner responsible for providing clinical and health economic information related to disease states and the appropriate utilization of Genentech medicines (approved and pipeline).
Senior Director, Project Management Genentech IncSenior Director, Project ManagementSouth San Francisco, CA$201,500–$374,100 / yearYou'll lead a large team of project managers and project leaders (employees and contingent workforce) accountable for planning and delivering approximately 150 active capital projects across the South San Francisco campus and related sites. You will be accountable for the safe, compliant, and efficient delivery of the portfolio, while simultaneously developing project management talent, strengthening organizational capabilities, and aligning outcomes with Site Services, Workplace Delivery strategies, and the broader Roche/Genentech Pharma Vision.
Global MSAT Senior DP Product Steward GenentechGlobal MSAT Senior DP Product StewardHillsboro, OregonThe Senior Large Molecule DP Product Steward is responsible for driving seamless technical industrialization and sustaining and improving the technical health of commercial products, starting from manufacturability decision through process performance qualification, supply maturity and optimization, and ultimately divestment. This role is accountable for delivering on the product’s technical strategic roadmap, which includes investigating and mitigating technical risks, implementing improvements, and aligning strategies with broader network objectives.
Principal Manufacturing Compliance Engineer Genentech IncPrincipal Manufacturing Compliance EngineerOceanside, CA$95,200–$176,800 / yearLeadership & Communication: Strong written and oral communication skills, with a track record of driving cross-functional alignment, prioritizing assignments independently, and mentoring teams under minimal supervision. Technical Expertise: Direct, hands-on experience with mammalian cell culture and/or purification of biopharmaceutical products, alongside thorough working knowledge of cGMPs, FDA, ICH, and European regulatory guidelines.
Scientist 3, Immunology GenentechScientist 3, ImmunologyThe candidate will be expected to work independently and collaboratively on pipeline projects and will be responsible for advancing exciting and novel research stage programs into early clinical development, providing both scientific and technical expertise and generating solid proof of concept data. Using state of the art techniques and technologies, the candidate will have the capacity to develop in vitro and in vivo skills to test the involvement of novel pathways and molecules in the pathogenesis of inflammatory diseases and to identify the mechanism of action (MOA) of new targets.
Director, Portfolio Strategy & Governance. GenentechDirector, Portfolio Strategy & Governance.Working across Finance, technology, data, and global teams, the Director will establish how opportunities are evaluated and prioritized, how investments and capacity are aligned to strategic priorities, and how progress, risks, dependencies, and value are surfaced to leadership. The Director, Portfolio Strategy & Governance will shape and lead the portfolio operating model for Digital Finance, creating the transparency, prioritization, governance, and accountability needed to translate digital strategy into measurable business outcomes.
Principal Scientist, Portfolio & gRED Interface-Biologics, AI for Drug Discovery (AIDD) GenentechPrincipal Scientist, Portfolio & gRED Interface-Biologics, AI for Drug Discovery (AIDD)You would be stepping into a role with outsized impact: driving portfolio applications of advanced ML models directly to gRED projects, serving as a trusted technical advisor to gRED leadership, and building a team of computational scientists who collectively raise the bar for what's possible in large molecule design. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.
Associate Program Director, Commercial Regulatory Affairs (CORA) GenentechAssociate Program Director, Commercial Regulatory Affairs (CORA)Must demonstrate working knowledge of the bio/pharma industry (compliance, legal, clinical affairs, regulatory and product marketing) as well as working knowledge of the legal and regulatory environment, as it relates to healthcare compliance in the bio/pharma industry (includes anti-kickback statutes, government fraud & abuse, off-label promotion, PhRMA Code, etc.). Commercial Regulatory Affairs (CORA) is part of the Global Product and Access Legal (GPAL) organization that interprets the needs of worldwide health authorities and provides regulatory intelligence necessary to generate and present information that meets the needs of health authorities, patients, purchasers and prescribers for Roche’s global Pharma Division.
Principal Quality Compliance Specialist, CVRM (Holly Springs) GenentechPrincipal Quality Compliance Specialist, CVRM (Holly Springs)Holly Springs, North CarolinaThis plant meets today’s demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines and is scalable to grow with the portfolio, which focuses on next-generation metabolic medicines specifically targeting the global obesity epidemic and Type 2 diabetes. This position is a unique opportunity to embed a robust, risk-oriented Quality Culture into the site's operational design, support a continuous improvement culture, and drive operational excellence, establishing Holly Springs as a center of excellence for aseptic drug product manufacturing.
Director, Activation & Capabilities Enablement (PAA) GenentechDirector, Activation & Capabilities Enablement (PAA)Key responsibilities include: Own the product vision, strategy, roadmap, and end-to-end lifecycle for the Contract Lifecycle Management (CLM) and Revenue Leakage (RL) product areas (note while CLM and RL will be the initital focus, product areas are subject to change based on demands of business)Build, lead, and mentor a team of agile product managers and leads, embodying servant leadership (VACC) principles and a player/coach mindset. Partner heavily with senior leadership and diverse user teams across PAA and Genentech Commercial Organization (CMG) to align product roadmaps with business strategy, ensuring continuous value delivery and user adoption.
Principal Scientist, SOP & Workflow Automation Champion, AI for Drug Discovery (AIDD) GenentechPrincipal Scientist, SOP & Workflow Automation Champion, AI for Drug Discovery (AIDD)The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. We have developed novel machine learning capabilities for large molecule discovery, but translating those capabilities into scalable, operationalized workflows at the organizational level requires both scientific credibility and strategic engineering acumen.