Operations Manager, Campus Development Genentech IncOperations Manager, Campus DevelopmentSouth San Francisco, CA$136,100–$252,700 / yearIf you thrive in dynamic, complex environments, possess a deep project management toolkit, and excel at distilling technical expertise into high-impact strategy, this role offers an unprecedented opportunity to help shape the future of our flagship campus. Genentech is embarking on a multi-decade transformation of its South San Francisco campus, and we are seeking a highly motivated, pragmatic Operations Manager to serve as the strategic operational partner and Chief of Staff to the Head of the IDO.
Therapeutic Area Analytics & Insights Manager - Solid Tumor GenentechTherapeutic Area Analytics & Insights Manager - Solid TumorThe Manager works flexibly within a matrix structure, sensing business priorities and reprioritizing work to meet organizational objectives responsible for delivering high-impact, data-driven insights that address key business challenges and support Genentech’s strategic objectives. Our Data, Digital, and Analytics empowers business partners across Commercial, Medical, and Government Affairs (CMG) to make impactful decisions by leveraging data, analytics, business products, and AI/ML to enable fast, targeted actions in rapidly evolving business contexts.
Principal Scientist, Structural Biology GenentechPrincipal Scientist, Structural BiologyYou have a proven track record leveraging insights into protein or protein-ligand molecular dynamics to enable, accelerate, and/or improve target identification, pocket discovery, binder discovery, ligand optimization and/or other steps of drug discovery. The ideal candidate will be well-versed in protein production and purification, structure determination of protein and protein-ligand complexes, and an expert in the use of computational and experimental techniques to characterize and understand protein dynamics and ligand binding.
R&D Business Insight and Digital Solution Lead GenentechR&D Business Insight and Digital Solution LeadIndustry & Trend Foresight: Leverage deep pharmaceutical informatics and technology trends to anticipate evolving scientific needs, evaluating emerging capabilities, including enterprise AI, Agentic workflows, generative ML, and multimodal data platforms—for strategic fit and enterprise scalability. Drive End-to-End Digital Execution: Lead complex, multi-squad software, and data delivery programs from concept to operationalization, maintaining a balanced focus between strategic architecture and hands-on delivery.
Scientist 3, Biochemical and Cellular Pharmacology GenentechScientist 3, Biochemical and Cellular PharmacologyExpert-level proficiency in culturing and performing assays on a wide range of mammalian and primary cells (including cardiomyocytes), as well as in stable cell line generation and gene-editing techniques (e.g., CRISPR). In this role, you will develop, validate, and execute sophisticated biochemical and cell-based assays in heterologous and physiologically relevant systems to evaluate drugs in cardiovascular, renal and metabolic areas.
Scientist 3, Animal Genetic Technologies, Warming lab GenentechScientist 3, Animal Genetic Technologies, Warming labIn a highly collaborative environment, the candidate will develop and use genome editing technology (including CRISPR) in combination with classic mouse genetics approaches to enable identification of novel modifiers of disease and validation of new targets for therapeutic intervention. Hands-on experience with relevant techniques, including CRISPR, NGS-based technologies (RNA-seq, ChIP-seq, scRNA-Seq, Long-Read sequencing, etc.), microscopy, flow cytometry and imaging.
Senior Scientist, Biochemical and Cellular Pharmacology GenentechSenior Scientist, Biochemical and Cellular PharmacologyDemonstrated expertise in receptor theory, signal transduction pathways, allosteric modulation, and biased signaling, along with hands-on experience across diverse GPCR assay platforms (e.g., cAMP, calcium flux, BRET/FRET, Beta-arrestin recruitment). Communicate Findings: Conduct comprehensive data analysis using advanced computational tools, and present high-quality scientific findings and strategic directions to internal stakeholders, project teams, and senior leadership.
NewBusiness Engagement Manager (BEM) - Eastern Washington - Eastern Oregon - Idaho - Montana Ecosystem Genentech IncBusiness Engagement Manager (BEM) - Eastern Washington - Eastern Oregon - Idaho - Montana EcosystemSeattle, WA$158,600–$294,600 / yearYou will utilize advanced understanding of the contracting landscape and specific needs of provider healthcare systems and their financial decision-makers (FDMs) to identify and implement innovative win-win opportunities that support improved patient outcomes, lower costs, and improved quality of care. Additionally, you will have proven inspiring, influencing, and leadership abilities applicable to both customer and internal audiences, including senior leadership, coupled with a solid understanding of external laws, codes, and company policies in the healthcare industry.
NewPrincipal Toxicologist-Scientist GenentechPrincipal Toxicologist-ScientistRemoteWorking in a collaborative team environment, the Principal Scientist leads the safety assessment of Genentech therapeutics by creating a best weight-of-evidence synthesis of existing knowledge and comprehensive investigations of toxicologic activity, strategic planning, and designing/implementing/supervising toxicology studies in support of program advancement. This Principal Scientist role is intended for an entry level portfolio toxicologist who can assume toxicology and safety leadership for multiple fast-moving development programs, including programs involving novel modalities and novel, accelerated, or otherwise nontraditional regulatory strategies.
NewUser Team Lead, HTO Expansion (Assembly and Packaging) Genentech IncUser Team Lead, HTO Expansion (Assembly and Packaging)Hillsboro, OR$138,000–$256,750 / yearThe Opportunity: As a member of the HTO Expansion Project Leadership Team, you will report to the HTO Site User Team Lead and spearhead efforts to expand Hillsboro site manufacturing capacity from start-up of new syringe inspection, device assembly and packaging assets to commercialize operations for new products. You will proactively provide process requirements and coordinate production needs and impacts, establishing a transition strategy of new technology integrating into the existing site to ensure success of new operations while operating the HTO commercial business successfully.
NewScientist 2 GenentechScientist 2Perform automated and semi-automated protein purification workflows using AKTA system- utilizing various types of affinity resins, polishing steps, along with quality assessment, to yield fit-for-purpose therapeutic molecules. Execute routine QC testing using SEC (HPLC) to evaluate purity, monomer content, and aggregation, while providing cross-functional support for concentration, endotoxin, and SDS-PAGE assays and LC/MS.
NewPrincipal / Senior Principal Scientist- Investigative Toxicology GenentechPrincipal / Senior Principal Scientist- Investigative ToxicologyOperating in newly established spaces characterized by emerging therapeutic modalities, you will establish unique preclinical safety roadmaps, interface directly with cross-functional project teams, lead matrixed experimental execution with laboratory staff, and partner with internal predictive modeling groups and external consortia to advance New Approach Methodologies (NAMs). The expected salary range for this position based on the primary location of San Franscico, CA is $141,500.00 - 262,900.00 (Principal Scientist) and $173,100.00 - $321,500.00 (Senior Principal Scientist) Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.
NewPrincipal Maintenance Specialist, Compounding and Filling - CVRM (Holly Springs) GenentechPrincipal Maintenance Specialist, Compounding and Filling - CVRM (Holly Springs)Holly Springs, North CarolinaWe're seeking a highly skilled Maintenance Specialist with direct Pharmaceutical compounding and filling Equipment experience who will be accountable for leading troubleshooting and issue resolution for highly complex mechanical challenges, providing coaching / mentorship / training of other Facilities personnel, and serve as owners or functional representatives on projects. This plant meets today’s demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines and is scalable to grow with the portfolio, which focuses on next-generation metabolic medicines specifically targeting the global obesity epidemic and Type 2 diabetes.
Principal Associate Scientist - Pharmaceutical Development Genentech IncPrincipal Associate Scientist - Pharmaceutical DevelopmentSouth San Francisco, CA$92,600–$172,000 / yearAs an integrated partner within the drug development ecosystem, Global Biologics Pharmaceutical Development is dedicated to effectively developing innovative and patient-centered parenteral drug products including Formulation and Process Development and Drug Delivery Systems. Our core business is to develop safe, innovative and effective drugs using cutting edge technologies for manufacturing process (Drug Substance and Drug Product), clinical supply, formulation, device, packaging, and analytical development.
Senior Marketing Manager, Ophthalmology Marketing Genentech IncSenior Marketing Manager, Ophthalmology MarketingSouth San Francisco, CA$161,800–$300,600 / yearSupports tailored and actionable omnichannel customer engagement, leveraging appropriate customer insights including customer journeys, personas, market/competitor insights and other data needed, collaborating closely with the Customer Marketer Lead. Self-authors derivative tactics for marketing campaigns leveraging existing and emerging technologies/capabilities, with a greater emphasis on new derivatives and incorporates post-Promotional Review Committee (PRC) edits and adjustments.
Scientist 2, Translational CVRM Genentech IncScientist 2, Translational CVRMSouth San Francisco, CA$85,500–$158,700 / yearThe CVRM (Cardiovascular, Renal, and Metabolism) Translational Biology group within Genentech Research and Early Development (gRED) is seeking a highly motivated and well-trained individual to advance drug discovery research and development efforts by executing in vivo experiments in rodent models of cardiometabolic diseases. Experience with rodent handling, various routes of drug administration (intravenous, intraperitoneal, intramuscular and subcutaneous), non-terminal and terminal blood sampling and tissue harvest.
State & Local Government Affairs Director GenentechState & Local Government Affairs DirectorTexasRemoteWorking collaboratively across internal business units and Genentech’s Customer Engagement (CE) field ecosystems, you will serve as a key strategic partner and a trusted mentor within the broader SLGA organization, with key responsibilities including: Advocate and lobby on Genentech's behalf with state legislative and executive branches by drafting policy solutions, preparing amendments, and delivering expert testimony at public hearings and events. As a member of this team, you will have the opportunity to collaborate closely with key stakeholders across Customer Engagement (CE) field ecosystems, state legislative and executive bodies, state policy partners, and external advocacy organizations to advance Genentech’s policy and business priorities.
NewSenior Director, Regional Lead Patient Experience (Midwest Region) Genentech IncSenior Director, Regional Lead Patient Experience (Midwest Region)Wichita, KSRemote$144,752–$268,753 / yearAs the Senior Director, Patient Experience Region Lead, you will serve as the strategic regional owner accountable for driving the operational delivery, performance, and scalable execution of Genentech's patient support and navigation services across your assigned territory. You will lead a high-performing, distributed regional team to navigate complex access challenges, optimize provider workflows, and enhance the overall patient experience across the full product portfolio.
Director, Field Leadership & Strategic Accounts – Eastern New England Ecosystem GenentechDirector, Field Leadership & Strategic Accounts – Eastern New England EcosystemBoston, MassachusettsYou contribute to and execute the strategic near and long-term vision and direction for the healthcare ecosystem set by the Executive Director, Healthcare Ecosystem and therapeutic areas to assist Squads in identifying partnerships and, under direction by the Squads executing partnerships which enhance customer experience, improve patient outcomes and deliver on business opportunities for Genentech. You have 8 or more years work experience with a minimum of 3 years previous field management experience and/or marketing experience with cross-functional industry experience in commercial life sciences (pharma or biotechnology) or related industry engaging with key healthcare ecosystem players (e.g., payers, health systems).
NewData Strategy & Analytics Specialist GenentechData Strategy & Analytics SpecialistBoston, MassachusettsWorking under the Data Strategy & Analytics Lead, you will partner with cross-functional teams—translating scientific protocols into robust analytical code, cohort extractions, and reproducible pipelines using multi-modal real-world data and clinical assets. You collaborate with central data engineering and governance teams to guide multi-modal data integration, applying common data models (OMOP, CDISC) and structured mappings across clinical trial and real-world assets.