Senior Medical Director, Clinical Development- POVE Vertex Pharmaceuticals IncSenior Medical Director, Clinical Development- POVEBoston, MA$280,600–$420,800 / yearGeneral Summary: The Senior Medical Director will define the clinical development strategy of povetacicept in primary membranous nephropathy, work with cross-functional multidisciplinary teams to define overall asset strategy as well as clinical trials strategy, design and execution, and may serve as the Medical Lead for clinical trials that will be conducted with these compounds. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Associate Director, GMP Operational Quality Vertex Pharmaceuticals IncAssociate Director, GMP Operational QualityBoston, MA$156,600–$234,800 / yearKey Duties and Responsibilities: Leads a team in the Quality Operations organization responsible for internal commercial operations in support of GMP manufacturing and testing activities, including disposition of intermediates, working cell banks and clinical and commercial drug products internally at Vertex manufacturing facilities. Serves as the Quality Lead for assigned clinical programs providing GCP compliance interpretation, consultation, and other support services necessary to maintain and/or improve the quality of Vertex research to ensure the protection of subjects' safety, rights, and well-being as well as the integrity and credibility of data generated.
Associate Director, Manufacturing Systems & Automation (CGT) Vertex Pharmaceuticals IncAssociate Director, Manufacturing Systems & Automation (CGT)Boston, MA$160,000–$240,000 / yearStrong implementation and commercialization experience in integrating first-of-kind equipment with manufacturing systems, automated batch review by exception, release by exception, chain-of-custody and chain-of-identification of autologous & allogeneic CGT products. We are seeking an experienced Associate Director, Manufacturing Systems and Automation - CGT to lead the manufacturing systems and automation team within the Biopharmaceutical Sciences - Cell & Gene Therapy (CGT) Manufacturing and Process Engineering organization.
Pain Territory Business Manager-Columbia/W STL, MO Vertex Pharmaceuticals IncPain Territory Business Manager-Columbia/W STL, MOSt. Louis, MO$140,000–$160,000 / yearThe TBM will work closely with Pain Territory Account Managers (PTAMs) who are also field-based reps within the geographic area who serve as account managers within hospitals/health systems and are responsible for driving and pulling through hospitals/health system volume and access as well as targeted physicians within their hospital networks. Collaborates compliantly with other field team members (e.g., PTAMs, field medical, HEOR, IDN and Payer Account teams) and headquarter colleagues to create aligned business plans, focus on strategic drivers, share best practices, and inform initiatives.
Executive Director, DMPK Vertex Pharmaceuticals IncExecutive Director, DMPKBoston, MA$268,000–$402,000 / yearGeneral Summary: We are seeking an accomplished and strategic leader to serve as Executive Director, Biotherapeutics DMPK-Bioanalysis (DMPK-BA), to guide the DMPK-BA strategy for our rapidly growing Biotherapeutics portfolio that includes protein, antibody, ADC, and cell and genetic therapies. The ideal candidate will bring deep strategic and scientific expertise in DMPK-BA for one or more biotherapeutic modalities described above, have demonstrated record of people management and leadership in a direct line as well as matrixed environment, and will have the ability to influence cross-functional teams and governance bodies at Vertex.
Director, Agent Intelligence - HYBRID ROLE Vertex Pharmaceuticals IncDirector, Agent Intelligence - HYBRID ROLEBoston, MARemote$216,400–$324,600 / yearYou will own the four primitives that all Vertex agents are built from: agent memory (personal and organizational), personas as code, skills (atomic tools and higher-order compositions), and the flagship agents that put those primitives to work on Vertex's hardest use cases. Design, build, and deploy custom AI agents for Vertex's highest-value enterprise use cases using Snowflake Cortex AI, Databricks AI, and agent orchestration frameworks, using these builds to harden the underlying primitives.
Seattle Research Technology Associate Director Vertex Pharmaceuticals IncSeattle Research Technology Associate DirectorSeattle, WA$164,400–$246,600 / yearGeneral Summary: This role leads laboratory technology support and continuous evolution across Seattle, and is the accountable Research Site Partner for Seattle: the primary DTE relationship holder for the site's research leadership, and the front door through which site requirements are captured, shaped, and routed into the correct cross-functional platform backlog. Operating within highly regulated GxP and SOX environments, this role remains accountable for operational excellence, financial stewardship, and risk management across a complex laboratory technology landscape, including ownership of the site's annual operating budget.
Global Travel Operations, Senior Manager Vertex Pharmaceuticals IncGlobal Travel Operations, Senior ManagerBoston, MA$117,600–$176,400 / yearManage the day-to-day operations of the outsourced travel support model including vendor management of Travel Management Company (TMC) across all geographic locations, ensuring compliance with company policies and procedures. The ideal candidate will possess advanced relationship-building skills, a proven ability to work with Senior Leaders, and navigate complex, high-pressure situations with professionalism and strategic insight.
Associate Director, Shift Quality Operations (Onsite) Vertex Pharmaceuticals IncAssociate Director, Shift Quality Operations (Onsite)Boston, MA$153,900–$230,900 / yearThe position partners closely with Manufacturing, Quality Assurance, Quality Control, MSAT, Engineering, Validation, and Supply Chain to support batch execution, deviation management, investigations, line clearance, contamination control, and continuous improvement. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Executive Director, Data & Methods Vertex Pharmaceuticals IncExecutive Director, Data & MethodsBoston, MA$270,600–$406,000 / yearThis leader will set AI and computational strategy that spans the full breadth of modern drug discovery and scientific therapeutic development; and will translate vision into scalable platforms, methods, and tools that serve every modality and measurably speed up discovery and translation, through the development of cutting-edge methods that leverage critical proprietary and public data to drive impact across our global research portfolio. Lead a multidisciplinary organization of scientists, engineers, and managers - building structure, growing other leaders, and driving organizational effectiveness as a leader of leaders.
Senior Director, US Market Access Strategy, Povetacicept (POVE) Vertex Pharmaceuticals IncSenior Director, US Market Access Strategy, Povetacicept (POVE)Boston, MA$232,000–$348,000 / yearVertex Pharmaceuticals operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), sickle cell disease, beta-thalassemia, and moderate to severe acute pain. This individual will guide the team responsible for developing and executing payer marketing, pricing, contracting, and evidence strategies that support POVE patient access while preparing for future label expansion opportunities.
Field Analytics & Reporting Associate Director, Kidney Vertex Pharmaceuticals IncField Analytics & Reporting Associate Director, KidneyBoston, MA$157,800–$236,600 / yearDemonstrated experience in understanding, facilitating, and communicating with field sales teams and field sales leadership to drive high field adoption and field performance in understanding and utilizing operational functions, identifying areas for improvement, and measuring field impact. This role will support strategy, design, roadmap planning, delivery, and adoption of all analytics across all field roles within the Strategic Customer Engagement Team including Field Account Managers, Regional/Area Managers, Strategic Account Leads, and Virtual Field Representatives.
Director, Knowledge Graph & Semantics - HYBRID ROLE Vertex Pharmaceuticals IncDirector, Knowledge Graph & Semantics - HYBRID ROLEBoston, MARemote$216,400–$324,600 / yearWe are seeking an experienced engineering leader to build and operate Vertex's enterprise Knowledge Graph and Semantic Layer: the unified, navigable representation of Vertex's data, concepts, and relationships that AI agents and analytical systems traverse to reason over our business. Design, build, and operate Vertex's enterprise knowledge graph spanning clinical, research, regulatory, and commercial domains, including ingestion, storage, query, and lifecycle management of nodes, edges, and properties.
Global Trade Compliance Process Owner Associate Director Vertex Pharmaceuticals IncGlobal Trade Compliance Process Owner Associate DirectorBoston, MARemote$148,000–$222,000 / yearThe BPO will collaborate with the GTC team on developing overall trade compliance strategy; further shape the strategy into repeatable scalable business processes and systems; functionally own the Global Trade Management (GTM) system and technology including interfaces with Vertex ERPs and other systems to support these processes; and act as a GTC Project Manager for process and systems implementations. The Associate Director, Global Trade Compliance (GTC) Business Process Owner (BPO) is responsible to develop and maintain processes and GTC systems that enable compliant, consistent, accurate and efficient filing of customs declarations for all Vertex exports and imports; as well as related GTC activities.
Manufacturing Science and Technology Principal Scientist Vertex Pharmaceuticals IncManufacturing Science and Technology Principal ScientistBoston, MA$145,500–$218,300 / yearStrong understanding of the technical aspects of manufacturing, testing, and controls and regulations governing pharmaceutical operationsStrong knowledge of cGMP requirements A strategic thinker with strong result-orientation and a sense of urgency to deliver quality results on time and in a highly ethical and professional manner Excellent communication and interpersonal skills with the ability to build strong cross-functional relationships and communicate complex issues and concepts enterprise-wideExcellent team player and be able to build and sustain organization respect and trust at all levelsProblem solver with a hands-on approach and ability to anticipate adverse scenarios and provide contingency plans to address them Resilient and able to work well in a demanding, fast paced entrepreneurial environment Sound judgment and business acumen with personal versatility and flexibility as business and team evolve Keeps current on professional knowledge, expertise and best practice; influential in the external environment in the area of aseptic processing and participates in industry consortia/ conferences relevant to the field. Work closely with colleagues in Process development to design and implement new technologies for aseptic filling of cell therapy drug products in novel device platforms; this includes working closely with Contract Development and Manufacturing Organizations (CDMOs) and engineering firms to design processes and equipment needed to perform aseptic filling operations in a GMP environment.
Financial Planning & Analysis Senior Manager Vertex Pharmaceuticals IncFinancial Planning & Analysis Senior ManagerBoston, MA$134,400–$201,600 / yearKey Duties and Responsibilities: Lead strategic, cross-functional initiatives across the COFO organization, partnering with Finance, General Ledger Accounting, Technical Accounting, SEC Reporting, Record-to-Report Strategy & Optimization, Procurement, Strategic Sourcing and DTE to drive process excellence and continuous improvement. Provide Finance Risk SME support for the Third-Party Risk Management (TPRM) program, including evaluation of supplier financial health assessments, review of elevated-risk suppliers, and partnership with Procurement to identify, assess and mitigate third-party financial risks.
Patient Safety Associate Medical Director Vertex Pharmaceuticals IncPatient Safety Associate Medical DirectorBoston, MA$200,000–$300,000 / yearAt Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. This role will optimizes patient safety of Vertex products and maintenance of compliance with the Pharmacovigilance regulations of Regulatory Agencies around the globe, through the effective and timely completion of Safety activities through the product life cycle.
Global Commercial Strategy Senior Director - T1D Vertex Pharmaceuticals IncGlobal Commercial Strategy Senior Director - T1DBoston, MA$228,000–$342,000 / yearThis is a high-impact role that requires a strong background in global strategic marketing, US market experience, expertise in market development for breakthrough therapies, and the ability to drive strategic initiatives in a fast-paced, dynamic environment. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Center Account Manager, Cystic Fibrosis (Midwest - Michigan and Illinois) Vertex Pharmaceuticals IncCenter Account Manager, Cystic Fibrosis (Midwest - Michigan and Illinois)Chicago, IL$136,000–$204,000 / yearThe Center Account Manager (CAM) will be responsible for achieving and maximizing territory sales goals by developing a strategic business plan, communicating thorough disease and product knowledge to healthcare professional customers (HCP's), and utilizing effective and appropriate selling strategies. This role will work cross-functionally within the sales/marketing team and compliantly across the entire organization (Managed Markets, Specialty Pharmacy, Patient Services, Medical, HR, Legal, Regulatory and Compliance teams).
Center Account Manager, Cystic Fibrosis (Midwest - Michigan and Illinois) Vertex Pharmaceuticals IncCenter Account Manager, Cystic Fibrosis (Midwest - Michigan and Illinois)Boston, MA$136,000–$204,000 / yearThe Center Account Manager (CAM) will be responsible for achieving and maximizing territory sales goals by developing a strategic business plan, communicating thorough disease and product knowledge to healthcare professional customers (HCP's), and utilizing effective and appropriate selling strategies. This role will work cross-functionally within the sales/marketing team and compliantly across the entire organization (Managed Markets, Specialty Pharmacy, Patient Services, Medical, HR, Legal, Regulatory and Compliance teams).