NewAssociate Scientist, Analytical Development and Quality Control Flagship Pioneering, Inc.Associate Scientist, Analytical Development and Quality ControlCambridge, MA USA$96,000–$126,500 / yearThe current Flagship ecosystem comprises 41 transformative companies, including: Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics, Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS). This candidate will contribute to: building efficient system for testing samples and delivering the data; method optimization and qualification to support characterization of novel nucleic acid therapeutics and LNP delivery vehicles.
Associate Scientist, Analytical Development and Quality Control Flagship Pioneering IncAssociate Scientist, Analytical Development and Quality ControlCambridge, MA$96,000–$126,500 / yearThe current Flagship ecosystem comprises 41 transformative companies, including: Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics, Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS). This candidate will contribute to: building efficient system for testing samples and delivering the data; method optimization and qualification to support characterization of novel nucleic acid therapeutics and LNP delivery vehicles.
Scientist I, In Vitro Pharmacology Flagship Pioneering IncScientist I, In Vitro PharmacologyBoston, MA$100,000–$126,500 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Many of these companies have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Senior Scientist I, Aerosol Design & Transport Flagship Pioneering IncSenior Scientist I, Aerosol Design & TransportCambridge, MA$126,000–$159,500 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies.
Scientist - Analytical Development, Regeneron Cell Medicines (RCM) Regeneron Pharmaceuticals IncScientist - Analytical Development, Regeneron Cell Medicines (RCM)Cambridge, MA$93,900–$153,300 / yearIn this role, you will support cell therapy programs by developing, optimizing, and executing biophysical assays to characterize lentiviral vectors, planning and performing experiments, developing new assay protocols, and analyzing and communicating results to advance therapies for patients. This position offers the opportunity to partner cross-functionally across RCM to meet program timelines and deliver high-quality analytical data in a fast-paced, science-driven organization making a meaningful difference to patients worldwide.
Scientist, RNA Chemistry Dyne Therapeutics IncScientist, RNA ChemistryWaltham, MA$118,000–$145,000 / yearThe Scientist applies established methodologies, troubleshoots routine technical challenges, and leverages expertise in modified RNA synthesis to produce high-quality oligonucleotides using state-of-the-art laboratory technologies. Primary Responsibilities Include: Independently perform synthesis of modified RNA oligonucleotides (ASO, siRNAs) incorporating diverse sugar and backbone chemistries at scales suitable for both in vitro and in vivo studies.
Senior Scientist, Machine Learning Flagship Pioneering IncSenior Scientist, Machine LearningCambridge, MA$132,000–$258,500 / yearExperience developing rigorous model evaluation frameworks, benchmarks, and validation strategies for molecular ML or scientific machine learning applications and an ability to curate, clean, integrate, and analyze complex, large-scale scientific datasets from multiple sources. Develop scalable featurization and modeling pipelines for large molecular datasets, including quantum chemistry outputs, conformer ensembles, protein-ligand interaction data, covalent reactivity data, and experimental chemoproteomics data.
Sr. Principal Scientist / Director, DMPK & Bioanalytical Sciences Flagship Pioneering IncSr. Principal Scientist / Director, DMPK & Bioanalytical SciencesCambridge, MA$179,000–$236,000 / yearThe company's initial therapeutic programs are designed to restore full-length protein production in diseases caused by premature termination codons (PTCs), collectively referred to as Stop Codon Disease, which affects approximately 10% of people with a rare genetic disease. Reporting to the Chief Scientific Officer, this role leads DMPK and bioanalytical strategy across nonclinical and clinical programs, operating as a hands-on scientific leader.
Senior Principal Scientist Waters CorporationSenior Principal ScientistMilford, MassachusettsIn addition to leading innovation in material design, you will help advance next-generation manufacturing strategies for Waters particle and bonded-phase production, including scalable and data-rich manufacturing approaches, advanced process characterization, and in-process analytical testing methodologies. As a Senior Principal Scientist within the BioSeparations Portfolio of the Chemistry & Lab Automation Business Unit, you will define and lead the scientific strategy for novel chromatographic materials and enabling chemistries for biologics ranging from oligonucleotides, viral vectors, and mRNA to proteins, peptides, and gene-editing therapeutics.
Senior Machine Learning Scientist, Climate & Hydrology Flagship Pioneering IncSenior Machine Learning Scientist, Climate & HydrologyCambridge, MA$127,000–$205,900 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Principal ML Scientist, Multimodal Biological Reasoning Flagship Pioneering IncPrincipal ML Scientist, Multimodal Biological ReasoningCambridge, MA$216,000–$297,000 / yearSource and shape portfolio use cases: interface with Flagship teams and portfolio company end-users to identify use cases, source data assets, define success criteria, and create end-user feedback loops for reasoning engines that are scientifically meaningful, tractable, and answer high-value questions with real world application. Guide technical architecture through a biological lens: guide multi-modal, multi-scale model design and ensure the system can ingest and reason over modalities relevant to mechanism-of-action reasoning, target discovery, perturbation biology, pathway reasoning, protein function, and autonomous discovery workflows.
Sr Scientist Waters CorporationSr ScientistMilford, MassachusettsWe collaborate with customers around the world to advance the release of effective, high-quality medicines, ensure the safety of food and water, and drive better patient outcomes by detecting diseases earlier, managing routine infections, and combating antibiotic resistance. Overview: Waters Corporation is seeking a Materials Scientist to help advance biotherapeutics through the research and development of new chemical tools that facilitate the characterization and quantitation of biological molecules.
Senior Scientist, Multimodal Biological Reasoning Flagship Pioneering IncSenior Scientist, Multimodal Biological ReasoningCambridge, MA$136,000–$264,000 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Pioneering Intelligence is seeking a Senior Scientist for Flagship''s ambitious efforts to build polyintelligent AI systems that unify human scientific expertise, machine intelligence, and nature's biological signals into multi-modal, multi-scale reasoning engines for biology.
Scientist / Engineer - Research & Development TechDigitalScientist / Engineer - Research & DevelopmentMarlborough, MAConduct routine and non-routine material characterization using methods such as GPC / SEC, HPLC, UPLC, NMR, FTIR, UV-Vis, solids content, titration, viscosity, density, surface tension, particle size analysis, DSC, TGA, microscopy, SEM, and film or coating evaluation, as applicable. • Demonstrated ability to safely handle wet chemistry, solvents, monomers, polymers, formulations, and hazardous chemicals while following site EHS requirements and laboratory procedures.
Senior Scientist, Computational Neuroscience Flagship Pioneering IncSenior Scientist, Computational NeuroscienceCambridge, MA$132,000–$259,000 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Scientist I Korro Bio IncScientist ICambridge, MA$120,000–$145,000 / yearUsing an oligonucleotide-based approach, Korro expects to bring its medicines to patients by leveraging its proprietary platform with precedented delivery modalities, manufacturing know-how, and established regulatory pathways of approved oligonucleotide drugs. Serve as a key biology contributor at the program team level; clearly present data, findings, and interpretation, and propose next steps informed by ongoing review of relevant scientific literature to cross-functional teams and company leadership.
Senior Scientist, Biologics Process Analytical Method Development Takeda Pharmaceutical Co LtdSenior Scientist, Biologics Process Analytical Method DevelopmentLexington, MA$137,000–$215,270 / yearThe actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. Develop, optimize, transfer, and sustain high-throughput, fit-for-purpose analytical methods for biologics development using phase-appropriate approaches and Analytical Quality by Design (AQbD) principles.
Principal Scientist, Agentic Systems for Pipeline Strategy Flagship Pioneering IncPrincipal Scientist, Agentic Systems for Pipeline StrategyCambridge, MA$179,000–$236,000 / yearThis role will serve as PI''s in-house expert in clinical and commercial strategy, and will lead the codification of therapeutic pipeline strategy as agentic capabilities: translating the judgment that today lives in the heads of senior strategic and translational leaders into autonomous systems that identify, evaluate, and prioritize opportunities to create new medicines at a level of scale and rigor that humans alone cannot achieve. Own the "legitimate patient need" problem end-to-end: define what it means for an agentic tool to identify and value a real, underserved patient need, what a product that addresses it looks like, and build the evaluations, ground-truth sets, and feedback loops that make agent outputs trustworthy enough to inform pipeline decisions.
Consulting Scientist Waters CorpConsulting ScientistMilford, MAWe collaborate with customers around the world to advance the release of effective, high-quality medicines, ensure the safety of food and water, and drive better patient outcomes by detecting diseases earlier, managing routine infections, and combating antibiotic resistance. We are seeking a Consulting Analytical Scientist to work in the Consumable and Lab Automation group to work in a dynamic environment with other R&D scientists and engineers to provide scientific contributions which impact new product development and solve problems that matter to our customers.
Senior Scientist / Senior Engineer, LNP Process Development Prime MedicineSenior Scientist / Senior Engineer, LNP Process DevelopmentCambridge, MA$145,000–$177,000 / yearLead the design, execution, and optimization of LNP processes to accommodate novel formulations and drug product manufacturing processes (LNP mixing and tangential flow filtration [TFF]) from bench through GLP/GMP scale, with emphasis on developing robust and scalable processes. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.