Senior Design Engineer Advanced 3D Modeler RTX CorpSenior Design Engineer Advanced 3D ModelerMarlborough, MAYou will conceptualize, design, integrate, and document mechanical-focused hardware using computer-aided design, mechanical analyses, and consistent coordination and communication across teams to ensure successful hardware performance. As part of our commitment to maintaining a secure hiring process, candidates may be asked to attend select steps of the interview process in-person at one of our office locations, regardless of whether the role is designated as on-site, hybrid or remote.
Senior Design Engineer Advanced 3D Modeler RTXSenior Design Engineer Advanced 3D ModelerMarlborough, MassachusettsActive and existing security clearance required after day 1 At RTX, the world’s largest aerospace and defense company, 185,000 great minds are united by purpose and inspired to make a difference solving the world’s most complex problems. You will conceptualize, design, integrate, and document mechanical-focused hardware using computer-aided design, mechanical analyses, and consistent coordination and communication across teams to ensure successful hardware performance.
Senior Threat Modeler State Street CorpSenior Threat ModelerQuincy, MA$120,000–$202,500 / yearYou will be responsible for performing threat modeling activities across enterprise applications, cloud platforms, APIs, and emerging technologies to identify security risks early in the development lifecycle and drive secure-by-design outcomes. Threat modeling enables the organization to proactively identify security weaknesses, reduce cyber risk, improve architectural resiliency, and ensure security requirements are incorporated into technology solutions from inception through deployment.
NewProcess Mechanical Lead Revit Modeler Hazen and SawyerProcess Mechanical Lead Revit ModelerManchester, NHHazen and Sawyer is seeking candidates for a full-time Principal CADBIM Designer position to join Hazen's diverse Northeast CADBIM Group. The candidate's primary role will be to serve as a Lead CADBIM Coordinator on various large Northeast water and wastewater projects.
Senior Principal Scientist, Computational Drug Discovery - Molecular Modeling & Cheminformatics Parabilis MedicinesSenior Principal Scientist, Computational Drug Discovery - Molecular Modeling & CheminformaticsCambridge, MA$200,000–$250,000 / yearIts lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between -catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/-catenin-driven tumors. Key responsibilities: Provide computational expertise toward, but not limited to, ternary complex design for degraders and other proximity-based modalities, hit identification and prioritization, hit-to-lead progression using multi-objective optimization, initiating new projects, new drug-target assessments, and advancing drug-pipeline projects toward the clinic.
Senior Principal Scientist, Computational Drug Discovery – Molecular Modeling & Cheminformatics Parabilis MedicinesSenior Principal Scientist, Computational Drug Discovery – Molecular Modeling & CheminformaticsCambridge, MA$200,000–$250,000 / yearProvide computational expertise toward, but not limited to, ternary complex design for degraders and other proximity-based modalities, hit identification and prioritization, hit-to-lead progression using multi-objective optimization, initiating new projects, new drug-target assessments, and advancing drug-pipeline projects toward the clinic. We are looking for someone who can independently support project teams across the full computational spectrum, from sampling peptide conformations and designing ternary complexes to building predictive property models and running cheminformatics analyses, without needing to hand off between a dedicated 3D modeler and a dedicated cheminformatician.