Principal Engineer / Architect Expert In Recruitment SolutionsPrincipal Engineer / ArchitectMalvern, PAYou will architect solutions that protect emerging product lines—including debit card and payments offerings—from Client fraud vectors, while remaining hands-on in code and system design. - 12+ years in software engineering with 5+ years focused on fraud prevention, payments, or banking technology.
Principal Data Platform Engineer Mitchell MartinPrincipal Data Platform EngineerKing of Prussia, PA$98,000–$140,000 / yearBachelor's degree in Computer Science, Engineering, Data Science, or related field, or equivalent practical experience. The successful candidate will work with generic technology platforms to ensure data quality and platform reliability.
NewSAP S/4 EPPM SME (Principal) The Dignify Solutions, LLCSAP S/4 EPPM SME (Principal)Newtown Square, PADesigns how project and portfolio performance is reviewed with real-time data from financial controlling and human resource management. Principal SAP S/4HANA architect for Enterprise Portfolio and Project Management (EPPM).
Principal Architect - Data EDI StaffingPrincipal Architect - DataCollingswood, NJEnterprise-Wide Architectural Data Leadership Define and evolve the enterprise data architecture across key data domains, including data platforms, integration, governance, analytics, and data security, ensuring cohesive and scalable end-to-end data solutions. Enterprise Data Strategy Development: Demonstrates the ability to design and implement comprehensive data strategies that support diverse use cases, including analytics, real-time transactional processing, bulk data movement, and API-driven data access.
Principal Architect, Marketing and Retailer Systems EDI StaffingPrincipal Architect, Marketing and Retailer SystemsCollingswood, NJEnterprise-Wide Architectural Leadership (20%) Define and evolve the enterprise application architecture across key domains, including application platforms, cloud platforms, integration, security, and operational services, ensuring cohesive and scalable end-to-end solutions across hybrid and multi-cloud environments. Deep experience with architectural patterns such as microservices, event-driven architectures, API-first design, domain-driven design, and distributed systems, along with application lifecycle management, service orchestration, and platform engineering.
Principal Data Engineer GTT, LLCPrincipal Data EngineerPhiladelphia, PAThe Principal Data Engineer will own the design, delivery, and maturity of production-grade data pipelines and data platforms, with a primary emphasis on real-time streaming, IoT telemetry, Databricks, Azure, data services for APIs and microservices, and reliable data products for downstream consumption. The ideal candidate should be comfortable spending significant time working directly with Databricks, Spark, SQL, Python/PySpark, Azure services, streaming architectures, data quality frameworks, pipeline automation, CI/CD, and production troubleshooting.
Principal Scientist, In-vivo CAR-T Johnson & JohnsonPrincipal Scientist, In-vivo CAR-TMalvern, PennsylvaniaAnalytical Reasoning, Biochemistry, Biotechnology, Chemistry, Manufacturing, and Control (CMC), Clinical Research and Regulations, Clinical Trial Designs, Coaching, Critical Thinking, Drug Discovery Development, Emerging Technologies, Molecular Diagnostics, Organizing, Pharmacovigilance, Presentation Design, Process Improvements, Productivity Planning, Scientific Research Collaborate with modelling experts and data scientists to identify opportunities where modelling or machine learning can reduce experimental burden, improve robustness, or define process design space.
Senior Principal Scientist, Bioanalytical Outsourcing Johnson and JohnsonSenior Principal Scientist, Bioanalytical OutsourcingSpring House, PAFull timeClinical Pharmacology, Clinical Trials Operations, Consulting, Drug Discovery Development, Industry Analysis, Pharmacodynamics, Pharmacokinetics, Pharmacology, Pharmacometrics, Program Management, Report Writing, Researching, Research Proposals, Scientific Research, Tactical Planning, Technical Credibility . The candidate will have a successful track record of problem solving, good organizational habits, excellent interpersonal skills, the ability to work under timelines, and the ability to collaborate within multidisciplinary teams is required.
Principal Scientist, In-vivo CAR-T Potency Method Development Johnson and JohnsonPrincipal Scientist, In-vivo CAR-T Potency Method DevelopmentMalvern, PAFull timeAnalytical Reasoning, Biochemistry, Biotechnology, Chemistry, Manufacturing, and Control (CMC), Clinical Research and Regulations, Clinical Trial Designs, Coaching, Critical Thinking, Drug Discovery Development, Emerging Technologies, Molecular Diagnostics, Organizing, Pharmacovigilance, Presentation Design, Process Improvements, Productivity Planning, Scientific Research . Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.
Principal Scientist, In-Vivo Car-T Johnson & JohnsonPrincipal Scientist, In-Vivo Car-TMalvern, PARequired Skills: Preferred Skills: Analytical Reasoning, Biochemistry, Biotechnology, Chemistry, Manufacturing, and Control (CMC), Clinical Research and Regulations, Clinical Trial Designs, Coaching, Critical Thinking, Drug Discovery Development, Emerging Technologies, Molecular Diagnostics, Organizing, Pharmacovigilance, Presentation Design, Process Improvements, Productivity Planning, Scientific Research. Collaborate with modelling experts and data scientists to identify opportunities where modelling or machine learning can reduce experimental burden, improve robustness, or define process design space.
Principal Scientist, Cell Line Genome Engineering Bristol Myers SquibbPrincipal Scientist, Cell Line Genome EngineeringPrinceton, NJ$135,800–$164,563 / yearExtensive hands-on and strategic experience with CRISPR-based genome engineering technologies (e.g., Cas9, Cas12a, dCas9, base-editing, prime-editing and related systems), and gene delivery methods (lentiviral, AAV, electroporation, transposon), with a proven track record of leveraging these tools to build, scale, and optimize cellular models that advance discovery programs. Demonstrated expertise in the design and generation of genetically engineered cellular systems (e.g., knockouts, knock-ins, targeted insertions, overexpression) using a range of approaches including CRISPR-based editing, viral delivery systems, and transposon-based technologies, with the ability to apply these strategically to drug discovery challenges.
Principal Scientist, Toxicology Johnson & JohnsonPrincipal Scientist, ToxicologySpring House, PennsylvaniaThe candidate will contribute to the success and growth of PSTS through active participation in internal and external committees / working groups and will closely interact with scientists in other functional areas including pathology, bioanalysis, toxicokinetics, and development project leaders in the US, Belgium, and China. Strong written and verbal communication skills and the ability to negotiate and influence decision-making processes, think and manage issues to resolution, and contribute to study teams and scientific discussions are required with prior experience in scientific data evaluation, integrated safety assessment, and scientific writing.
Principal Scientist, Molecular Genomics Bristol Myers SquibbPrincipal Scientist, Molecular GenomicsPrinceton, NJ$138,520–$167,849 / yearThe successful candidate will provide scientific leadership in assay strategy, technology evaluation, biomarker development, clinical sample analysis, vendor oversight, and cross-functional collaboration to generate high-quality genomics data that informs clinical trial decision-making and advances Bristol Myers Squibb's research and development pipeline. Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
Senior Principal Scientist, Biologics Discovery Process Research Integrator Johnson & JohnsonSenior Principal Scientist, Biologics Discovery Process Research IntegratorSpring House, PennsylvaniaAnalytical Reasoning, Biochemistry, Biotechnology, Chemistry, Manufacturing, and Control (CMC), Clinical Research and Regulations, Clinical Trial Designs, Collaboration, Data Synthesis, Drug Discovery Development, Molecular Diagnostics, Pharmacovigilance, Process Improvements, Productivity Planning, Program Management, Scientific Research, Tactical Planning, Technical Credibility Building trusted cross‑functional partnerships and influencing decision‑making across Therapeutics Discovery (TD), Preclinical Sciences & Translational Safety (PSTS), Therapeutic Areas (TAs), and TDS in matrixed governance and technical forums.
Senior Principal Scientist, Biologics Discovery Process Research Integrator – Protein Expression and Scale-Up Johnson & JohnsonSenior Principal Scientist, Biologics Discovery Process Research Integrator – Protein Expression and Scale-UpSpring House, PennsylvaniaAnalytical Reasoning, Biochemistry, Biotechnology, Chemistry, Manufacturing, and Control (CMC), Clinical Research and Regulations, Clinical Trial Designs, Collaboration, Data Synthesis, Drug Discovery Development, Molecular Diagnostics, Pharmacovigilance, Process Improvements, Productivity Planning, Program Management, Scientific Research, Tactical Planning, Technical Credibility The role will provide integrative technical leadership grounded in mammalian expression, cell line development, and scale-up expertise, ensuring that expression feasibility, manufacturability, productivity, product quality, and scalable production considerations are incorporated into molecule selection, material supply planning, and program strategy.
Principal Data Scientist - Oncology Johnson and JohnsonPrincipal Data Scientist - OncologySpring House, PAFull timeWork with Data Science & Digital Health colleagues, IT and DevOps teams to deploy and manage the graph database infrastructure, focusing on high availability, scalability, and recovery operations specifically geared toward Oncology R&D needs and applications. Cambridge, Massachusetts, United States of America, Raritan, New Jersey, United States of America, San Diego, California, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America.
NewPrincipal Scientist, Early Development ADSI Johnson & JohnsonPrincipal Scientist, Early Development ADSIMalvern, PennsylvaniaAnalytical Reasoning, Biochemistry, Biotechnology, Chemistry, Manufacturing, and Control (CMC), Clinical Research and Regulations, Clinical Trial Designs, Coaching, Critical Thinking, Drug Discovery Development, Emerging Technologies, Molecular Diagnostics, Organizing, Pharmacovigilance, Presentation Design, Process Improvements, Productivity Planning, Scientific Research The Principal Scientist, Early Development Analytical Development Scientific Integrator (ADSI) will be responsible for the following: Provide strategic and technical leadership in analytical development and lead a cross-functional scientific team consisting of members from each of the AD sub-functions.
Talent Data Management Associate Director - Principal Data Architect (Location Flexible) RSMTalent Data Management Associate Director - Principal Data Architect (Location Flexible)Blue Bell, PA$136,800–$242,000 / yearAs the organization's HR data architecture leader, this position is responsible for designing modern relational database solutions and Azure-based data warehouse architecture that enable trusted, high-quality data for downstream analytics and Power BI reporting. This role leads the design, governance, and evolution of the Talent Operational Data Store (ODS), ensuring HR data is scalable, secure, reliable, and optimized to support enterprise reporting, analytics, and business intelligence.
Principal Specialist, Regulatory Affairs West Pharmaceutical ServicesPrincipal Specialist, Regulatory AffairsExton, PAWest solved the problem of supplying penicillin in mass quantities to the US Government during World War 2. Through our work to deliver thousands of life-saving and life-enhancing injectable medicines to millions of patients daily, West's indelible mark on the healthcare industry has just begun. In addition, the Principal Specialist mentors team members, and provides support for global regulatory approvals (beyond US and EU), commercialized products, and ensures compliance with West Pharmaceutical Services, Inc. (West) and government requirements.
NewSenior Principal Scientist, Biologics Discovery Process Research Integrator - Protein Expression And Scale-Up Johnson & JohnsonSenior Principal Scientist, Biologics Discovery Process Research Integrator - Protein Expression And Scale-UpMalvern, PARequired Skills: Preferred Skills: Analytical Reasoning, Biochemistry, Biotechnology, Chemistry, Manufacturing, and Control (CMC), Clinical Research and Regulations, Clinical Trial Designs, Collaboration, Data Synthesis, Drug Discovery Development, Molecular Diagnostics, Pharmacovigilance, Process Improvements, Productivity Planning, Program Management, Scientific Research, Tactical Planning, Technical Credibility. The role will provide integrative technical leadership grounded in mammalian expression, cell line development, and scale-up expertise, ensuring that expression feasibility, manufacturability, productivity, product quality, and scalable production considerations are incorporated into molecule selection, material supply planning, and program strategy.