Principal Scientist, Agentic Systems for Pipeline Strategy Flagship Pioneering IncPrincipal Scientist, Agentic Systems for Pipeline StrategyCambridge, MA$179,000–$236,000 / yearThis role will serve as PI''s in-house expert in clinical and commercial strategy, and will lead the codification of therapeutic pipeline strategy as agentic capabilities: translating the judgment that today lives in the heads of senior strategic and translational leaders into autonomous systems that identify, evaluate, and prioritize opportunities to create new medicines at a level of scale and rigor that humans alone cannot achieve. Own the "legitimate patient need" problem end-to-end: define what it means for an agentic tool to identify and value a real, underserved patient need, what a product that addresses it looks like, and build the evaluations, ground-truth sets, and feedback loops that make agent outputs trustworthy enough to inform pipeline decisions.
Principal Scientist, Computational Biology Bristol-Myers Squibb CoPrincipal Scientist, Computational BiologyMARemote$166,770–$202,086 / yearIPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learning-across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. Hands on experience analyzing and integrating high-dimensional molecular datasets such as multi-omics (RNA-seq, ATAC-seq, proteomics, ChIP-seq/CUT&RUN), single cell profiling (CITE-seq, scATAC-seq, perturb-seq) and/or spatial profiling to derive novel biological insights.
Pathology Computational Scientist Brigham and Women's HospitalPathology Computational ScientistBoston, MA$93,953.60–$136,739.20 / yearApplications will include forecasting microbial population dynamics in the gut, characterizing the impact of spatial structure of the microbiome, predicting impact of the microbiome on host phenotype, tracking infections in human populations, elucidating microbial metabolism, and discovering functions of uncharacterized microbial metabolites and proteins. With recent funding from the Massachusetts Life Sciences Center, the Lab has built a state-of-the-art compute cluster with extensive GPU and CPU nodes, with the objective of making advanced deep learning technologies broadly available to microbiome researchers.
Research Technology Specialist - Human Nutrition Research Center on Aging Tufts UniversityResearch Technology Specialist - Human Nutrition Research Center on AgingBoston, MassachusettsKnowledge and experience typically acquired by: Bachelor's Degree in biomedical engineering, computer science, data science, electrical engineering, bioinformatics, biostatistics, computational biology, applied mathematics, or a related quantitative or technical field. This position will contribute to data-rich research projects involving human studies, observational cohorts, lifestyle interventions, biomarker analytics, wearable and sensor-derived data, and high-dimensional omics datasets.
Director, Oncology Data Science Merck & Co IncDirector, Oncology Data ScienceBoston, MA$194,100–$305,600 / yearRequired Skills: Bioinformatics, Cancer Genomics, Cancer Research, Computational Biology, Computational Methods, Data Science, Deep Learning, High Dimensional Data Analysis, Immuno-Oncology, Machine Learning (ML), Multimodal Analysis, Oncology, Real World Data, Statistical Learning. Analyze, summarize and visualize the findings from large multi-modal clinico-genomic datasets which include bulk RNAseq, WES/WGS, imaging, epigenetic profiling, single-cell RNAseq, and proteomics data from oncology clinical trials and real-world datasets.
Computational Biologist I Foundation Medicine IncComputational Biologist IBoston, MA$112,560–$133,000 / yearIn addition to research, this role develops sub-specialization in the data architecture supporting the teams efforts, including pipeline workflow development, cloud-based data storage, and maintaining data quality and integrity. Proficiency in Unix or Unix-like operating systems; proficiency in one or more programming languages such as Python, R, SQL, or similar scientific computing languages; familiarity with other programming or scripting languages.
Principal Scientist - CMC Statistician SanofiPrincipal Scientist - CMC StatisticianFramingham, MA$122.25–$176.58 / hourAs part of the development of Sanofi's pharmaceutical products, the R&D Data Sciences department and more specifically the Statistics department for the Chemical Manufacturing Control (CMC), CMC Statistics, is responsible for contributing to statistical support, modelling, digitalization, decision-making and filing of new product registration files. Experience: Minimum 3 years (PhD) or 6 years (Master's) of experience as a Statistician in CMC (Chemistry, Manufacturing and Control) studies/activities, industrial statistics, manufacturing, or closely related fields such as cosmetics or food industry.
NewMachine Learning Data Engineer (Aim2) PfizerMachine Learning Data Engineer (Aim2)Cambridge, MA$106,000–$176,600 / yearThe successful candidate will integrate and curate complex biological and clinical datasets for machine learning model development and deployment, while building scalable cloud-based data pipelines that enable insight generation across IMRU's proprietary and external data resources. Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
NewMachine Learning Data Engineer (AIM2) PfizerMachine Learning Data Engineer (AIM2)MassachusettsThe successful candidate will integrate and curate complex biological and clinical datasets for machine learning model development and deployment, while building scalable cloud-based data pipelines that enable insight generation across IMRU's proprietary and external data resources. Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Vice President, Gene Editing Core Intellia TherapeuticsVice President, Gene Editing CoreCambridge, MA$327,100–$399,900 / yearThis role will develop strategy, implement, and lead state-of-the-art genomics and RNA labs, managing support for a portfolio of projects by developing and implementing gene editing analysis technologies and platforms as well as gene editing component production (sgRNA, mRNA) and will work close together with project teams to drive the organization's discovery projects to development candidates. Collaborates across Platform Innovation and Delivery Innovation to advance novel nucleases, insertion strategies, new technologies, delivery advancements, and develop assays to assess the potential for unintended genomic changes.
Biological Structures Data Engineer I/II Iambic TherapeuticsBiological Structures Data Engineer I/IIBoston, MassachusettsWorking alongside ML scientists, you will design, implement, and harden the workflows that prepare experimental structural (e.g., protein–ligand complexes) and affinity data for training, and help create and ingest large volumes of high-quality computationally generated synthetic data. Iambic Therapeutics is seeking a Biological Structures Data Engineer to join the NeuralPLexer team and own the data pipelines for acquiring, curating, and transforming experimental and synthetic data to train the next generation of NeuralPLexer models.
Scientist II / Senior ML Scientist, Cofolding and Structure-Aware ML Lila Sciences IncScientist II / Senior ML Scientist, Cofolding and Structure-Aware MLCambridge, MA$228,000–$358,000 / yearYou will work with ML researchers, computational chemists, computational biophysicists, data engineers, and drug discovery teams to develop models that learn from DEL and related datasets, connect molecular and protein context, and improve AI-driven discovery decisions. Use contrastive learning, representation learning, self-supervised learning, or related methods where they help improve cofolding models trained on molecules, proteins, structures, and experimental readouts.
Post-Doctoral Research Fellow – HBV Biomarkers and Liquid Biopsy Massachusetts General Physicians OrganizationPost-Doctoral Research Fellow – HBV Biomarkers and Liquid BiopsyBoston, Massachusetts$70,000–$71,750 / yearInstitution: Massachusetts General Hospital (MGH), Harvard Medical SchoolDepartment: Medicine – Gastroenterology / HepatologyA Postdoctoral Research Fellow position is available at Massachusetts General Hospital and Harvard Medical School to support a research project focused on the development and clinical validation of blood-based biomarkers for early detection and monitoring of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus (HBV) infection. The fellow will work closely with Dr. Ray Chung and Dr. Doan Dao, investigators at MGH and collaborate with external partners, including the Baruch S. Blumberg Institute (BSBI), PA, USA.This role offers a unique opportunity to engage in translational research spanning computational biology, molecular diagnostics, and clinical data integration.
Postdoctoral Research Fellow - Computational Biologist - Gillani Lab Dana-Farber Cancer Institute IncPostdoctoral Research Fellow - Computational Biologist - Gillani LabBOSTON, MA$72,000–$76,385 / yearThey will develop and support data processing and analysis tools, create new algorithms for focused research questions in bulk and single cell tumor analysis, integrate tools and databases into existing high-throughput pipelines, and drive projects to completion and publication. This Postdoctoral Computational Biologist will also help with the generation of tools needed for manipulating and preparing data for display; transferring data to external collaborators and data repositories; and will also help maintain, support, and document shared tools, code, and data sets.
Post-Doctoral Research Fellow – HBV Biomarkers and Liquid Biopsy Mass General BrighamPost-Doctoral Research Fellow – HBV Biomarkers and Liquid BiopsyBoston, Massachusetts$70,000–$71,750 / yearInstitution: Massachusetts General Hospital (MGH), Harvard Medical SchoolDepartment: Medicine – Gastroenterology / HepatologyA Postdoctoral Research Fellow position is available at Massachusetts General Hospital and Harvard Medical School to support a research project focused on the development and clinical validation of blood-based biomarkers for early detection and monitoring of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus (HBV) infection. The fellow will work closely with Dr. Ray Chung and Dr. Doan Dao, investigators at MGH and collaborate with external partners, including the Baruch S. Blumberg Institute (BSBI), PA, USA.This role offers a unique opportunity to engage in translational research spanning computational biology, molecular diagnostics, and clinical data integration.
Postdoctoral Research Fellow - Multiomics Dana-Farber Cancer Institute IncPostdoctoral Research Fellow - MultiomicsBOSTON, MA$72,000–$76,385 / yearThe successful candidate will work at the intersection of computational biology, genomics, epigenomics, artificial intelligence, and clinical data science, contributing to projects that leverage cutting-edge multiomic datasets to develop predictive models of therapy response and identify clinically actionable biomarkers. We are seeking a highly motivated Postdoctoral Research Fellow to join the Center for Functional Cancer Epigenetics (CFCE) at Dana-Farber Cancer Institute and become part of a multidisciplinary project led by Paloma Cejas and Henry Long, in collaboration with AITIA, an artificial intelligence and computational biology company.
Associate Director, Functional Genomics, Data Science Merck & Co IncAssociate Director, Functional Genomics, Data ScienceCambridge, MA$176,200–$277,300 / yearRequired Skills: Amazon Web Services (AWS), Bioinformatics, Biostatistics, Computer Science, CRISPR-Cas System, Data Engineering, Data Modeling, Data Science, Data Visualization, Genome, Genomics, Hypothesis Testing, Linux Environments, Machine Learning (ML), Model Fine-Tuning, Omics, Single-Cell Genomics, Software Development, Stakeholder Relationship Management, Statistical Design of Experiments (DOE), Statistical Programming. Integrate functional genomics and imaging derived results with high throughput transcriptomics and proteomics datasets to build multi evidence target prioritization packages for multiple stages of drug discovery.
Post-Doctoral Research Fellow - HBV Biomarkers And Liquid Biopsy Brigham and Women's HospitalPost-Doctoral Research Fellow - HBV Biomarkers And Liquid BiopsyBoston, MA$70,000–$71,750 / yearA Postdoctoral Research Fellow position is available at Massachusetts General Hospital and Harvard Medical School to support a research project focused on the development and clinical validation of blood-based biomarkers for early detection and monitoring of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus (HBV) infection. This project involves analysis of tumor-derived HBV-host junction sequences (HBV-JS) using next-generation sequencing (NGS), quantitative PCR (qPCR), and integration of molecular data with clinical and imaging datasets.
Post-Doctoral Research Fellow - HBV Biomarkers and Liquid Biopsy Brigham and Women's HospitalPost-Doctoral Research Fellow - HBV Biomarkers and Liquid BiopsyBoston, MA$70,000–$71,750 / yearA Postdoctoral Research Fellow position is available at Massachusetts General Hospital and Harvard Medical School to support a research project focused on the development and clinical validation of blood-based biomarkers for early detection and monitoring of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus (HBV) infection. This project involves analysis of tumor-derived HBV-host junction sequences (HBV-JS) using next-generation sequencing (NGS), quantitative PCR (qPCR), and integration of molecular data with clinical and imaging datasets.
Staff Engineer, Machine Learning Life Sciences InariStaff Engineer, Machine Learning Life SciencesCambridge, Massachusetts$148,530–$204,250 / yearNetwork analysis: Experience with graph neural networks or network analysis tools (e.g., networkx) for modeling complex biological relationships (e.g., gene regulatory networks, protein-protein interaction networks). Reuters: Gene Editing Wheat: https://www.reuters.com/markets/commodities/australian-trial-gene-edited-wheat-aims-10-bigger-yields-2024-05-23/#:~:text=CANBERRA%2C%20May%2023%20(Reuters),and%20make%20farming%20more%20sustainable .