Postdoctoral Scientist - Gene Therapy Biodistribution & Molecular Biology (Cns) Eli Lilly and CompanyPostdoctoral Scientist - Gene Therapy Biodistribution & Molecular Biology (Cns)Boston, MA$58,000–$123,200 / yearApply a broad toolkit of molecular and bioanalytical techniques, including: PCR-based approaches (PCR, qPCR, ddPCR, stem-loop PCR, vg/dg dose quantification) for vector genome and transcript quantification; ELISA and immunoassays for protein expression and biomarker analysis; LC-MS-based quantitative bioanalysis where applicable; Immunohistochemistry (IHC) and tissue-based spatial analyses to enable regional CNS characterization; Next-generation sequencing (NGS) methods to support vector tracking, expression profiling, or integration-related analyses. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL).
Postdoctoral Scientist - Neuroscience (Synuclein Biology) Eli Lilly and CompanyPostdoctoral Scientist - Neuroscience (Synuclein Biology)Boston, MA$58,000–$123,200 / yearOur current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL). The team brings together expertise in -synuclein biology, iPSC-derived neuronal models, high-content imaging, and target validation, with active efforts spanning small molecule discovery, gene therapy, and biomarker development.
Senior/Principal Scientist, MPN Biology, Translational Sciences PharmaEssentia U.S.A.Senior/Principal Scientist, MPN Biology, Translational SciencesBEDFORD, MAFull timeFounded in 2003 by a team of Taiwanese American executives and renowned scientists from U.S. biotechnology and pharmaceutical companies, today we are listed on the Taipei Exchange (TPEx: 6446) and are expanding our global presence with operations in the U.S., Japan, China and Korea, along with a world-class biologics production facility in Taichung. In this position, you will utilize your expertise in MPN stem cell biology, driver mutation signaling pathways, in vivo MPN mouse models and biomarker discovery to guide proof-of-concept (POC) studies, drug development and biomarker strategies, optimize dosing regimens, and ensure the safety and efficacy of investigational drugs.
Analyst II, Quality Control Molecular Biology The Steely GroupAnalyst II, Quality Control Molecular BiologyWoburn, MAThe QC Analyst II will perform analytical methods including but not limited GC titer determination by ddPCR and qPCR, impurity testing, and other methods as needed to support in-process, drug substance and drug product release, stability to support AAV-based gene therapy programs. Routine work includes release and stability testing, critical reagent qualification, method validation and transfer, critical reagent qualification, analyzing data, and authoring technical documents.
Postdoctoral Research Fellows - Center For Craniofacial And Skeletal Biology ForsythPostdoctoral Research Fellows - Center For Craniofacial And Skeletal BiologyCambridge, MAThe research studies focus on the elucidation of molecular and cellular mechanisms underlying stem cell self-renewal, cell fate determination and differentiation, crosstalk of signaling pathways, tissue repair and regeneration, and stem cell-based and gene-editing therapies. Technical troubleshooting includes but not limited to the area of PCR genotyping and qPCR, lentivirus-mediated gene expression, microscopes and digital imaging techniques, and phenotypic characterizations of genetically modified mouse mutants.
Project Team Leader, Biology Orum Therapeutics IncProject Team Leader, BiologyLexington, MAThis is a pivotal role that sits between hands-on execution and research leadership: you will translate strategic direction into actionable program plans, provide scientific leadership to a small team of scientists, and serve as the biology point person on cross-functional project teams. PhD in cancer biology, molecular/cell biology, pharmacology, biochemistry, or a related field, with 8+ years or a Master's degree with commensurate experience 12+ years and a demonstrated record of independently leading discovery programs.
Computational Biology & Bioinformatics Lead Institute for Protein InnovationComputational Biology & Bioinformatics LeadBoston, Massachusetts$200,000–$240,000 / yearThe Institute's deep protein expertise, collaborative spirit and research tools are powering new biomedical and therapeutic discoveries with a growing community of researchers at Harvard Medical School, Boston Children's Hospital and other institutions across Greater Boston and beyond. Founded in 2017 and located in Boston’s Longwood Medical Area, the Institute’s three-pronged strategy is to build protein tools, conduct related internal research and develop educational programs for the protein science and biological research communities.
Process Development Associate Scientist- Biological And Structural Characterization Amgen Inc.Process Development Associate Scientist- Biological And Structural CharacterizationCambridge, MAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Senior Scientist LancesoftSenior ScientistCambridge, MAProficiency and hands-on experience in applying a wide range of cellular and molecular biological methods (in particular: CRISPR, qRT-PCR, cloning, cell culture, cell viability/death assays, transient/stable cell line generation, immunoblotting, FACS) and softwares such as Microsoft Office, prism, spotfire. Additionally, the candidate will assess new state-of-the-art technologies and explore their potential for enhancing our ability to identify targets and create more accurate complex-disease models.
Advanced Process Analytics Scientist Integrated Resources, IncAdvanced Process Analytics ScientistCambridge, MassachusettsContractorThis includes but not limited to developing tools for deeper understanding of the underlying biological phenomena that lead to differences in product quality (e.g., via metabolic flux modeling, proteomics modeling, bio-informatics); develop robust spectral models correlating to valuable metabolites, cell mass, and product quality attributes (e.g., chemometric models for NIR, Raman). To reach that goal, we are exploring the application of state of the art data science and machine learning while leveraging available process knowledge and a wealth of development and manufacturing data to build end to end product quality predictive meta-models.
Senior Scientist I, Microfluidics Ampersand BiomedicinesSenior Scientist I, MicrofluidicsBoston, MassachusettsThe successful candidate will collaborate closely with molecular biologists on vector design, cell-based assay development, and library generation strategies before partnering with microfluidics engineers to integrate novel assays into robust high-throughput screening workflows. This scientist will play a central role in developing library cell systems and biological assays that enable the discovery of enhanced, engineered antibody and protein variants, while contributing to the continued evolution of Ampersand's high-throughput screening platform.
Associate Scientist-II Integrated Resources, IncAssociate Scientist-IICambridge, MassachusettsFull timeThe successful candidate will have hands-on experience with a variety of biochemical methods relevant for the study of neurodegenerative diseases and the ability to utilize these methods for target engagement studies to support drug discovery and development projects. As Associate Scientist II, the expectation is that the incumbent is capable of planning and executing experiments with limited supervisorial oversight including the analysis and interpretation of the experimental results to achieve agreed upon objectives.
NewSenior Associate Scientist, Cellular Genomics Pfizer IncSenior Associate Scientist, Cellular GenomicsCambridge, MA$68,600–$114,300 / yearExperience with genomics data analysis, quality control, visualization, or reproducible bioinformatic workflows for bulk RNA sequencing, single-cell and single-nucleus RNA sequencing, spatial transcriptomics, targeted sequencing, immune repertoire sequencing, epigenomics assays, or related genomic technologies. Bachelor's degree in Bioinformatics, Computational Biology, Genomics, Systems Biology, Computer Science & Molecular Biology, Data Science with biological applications, Biological Sciences with significant computational biology course work, or a related discipline with 0-3 years of relevant experience.
Research Scientist Integrated Resources, IncResearch ScientistAndover, MassachusettsContractorBS or MS in biological sciences or related field; experience in more than one of the following: mammalian cell culture, large scale DNA assembly and characterization, genetic recombination technology, next-generation sequencing, computational methods and tools for analysis, and statistics; biological experience in one of the following: molecular biology, protein engineering, immunology, or cell biology. Seeking a highly motivated scientist with excellent documentation skills who is able to contribute in a multidisciplinary team setting, prioritize and perform multiple tasks in a dynamic environment, and execute detailed technical protocols meticulously.
Biomarker Scientist Integrated Resources, IncBiomarker ScientistAndover, MassachusettsFull timeExtensive experience with cell biological techniques such as cell culture (cell lines as well as primary immune cells), cell isolation from human blood and mouse tissues, immune-staining for multi-color flow assays is required. The lab based role entails performing deep immune-phenotyping and phospho-signaling assays of human, mouse and cynomolgus cells, receptor quantification, receptor internalization, and receptor occupancy to support portfolio projects.
Associate Scientist I Integrated Resources, IncAssociate Scientist ICambridge, MassachusettsContractorThey are also responsible for providing these same services, including the preparation of biological solutions, microbiological growth media, cell culture media, and providing technical assistance to all ongoing projects. The Supervisor ensures that the site provides a high quality and efficient service and is directly responsible for the technical personnel who support this function, including their training and development.
Associate Scientist II Integrated Resources, IncAssociate Scientist IICambridge, MassachusettsContractorPossess significant expertise in animal models of neurodegenerative diseases, especially Alzheimer-related models, and experience with handling and dosing of rodents, tissues and fluids collection (CSF, plasma). The successful candidate will be involved with the design and execution of experiments to support the discovery of client drug targets and the development of small and large molecule drugs for the treatment of neurodegenerative diseases.
Bench Scientist Integrated Resources, IncBench ScientistAndover, MassachusettsFull timeBS or MS in biological sciences or related field; experience in more than one of the following: mammalian cell culture, large scale DNA assembly and characterization, genetic recombination technology, next-generation sequencing, computational methods and tools for analysis, and statistics; • Biological experience in one of the following: molecular biology, protein engineering, immunology, or cell biology; strong organizational, analytical, problem solving, interpersonal, and communication skills; and ability to work as part of a team and on individual projects. Through working in partnership with everyone from patients to health care providers and managed care organizations to world governments and non-governmental organizations, they ensure to continue to deliver on their commitments to the patients, customers, and shareholders who rely on them.
Senior Scientist I, Data Science Senda BiosciencesSenior Scientist I, Data ScienceCambridge, MA$130,000–$170,000 / yearAs a key member of the Sail Biomedicines Data Science team, the Senior Scientist I will operate at the interface of platform and program, applying data-driven approaches to champion broad platform efforts and hands-on analysis of preclinical datasets to transform the treatment landscape for autoimmune diseases, and beyond. Join our team and drive the future of programmable eRNATM therapeutics and In Vivo CAR-T therapies- where AI-driven biology, targeted delivery systems and next-generation immunotherapy converge to redefine what's possible for patients.
Marine Scientist- Fisheries Observer Fathom Resources LLCMarine Scientist- Fisheries ObserverBoston, MA$315–$350 / dayMarine Fisheries Biologist Requirements specific to Observing : Candidates must possess: A good attitude with the desire to get your hands dirty; Bachelor’s degree with a major in one of the biological sciences from an accredited four-year college or university; At least 30 semester hours in any combination of scientific or technical courses such as biology, chemistry, statistics entomology, animal husbandry, physics or mathematics, of which at least six (6) semester hours are in marine science or fisheries. Marine and fisheries Data collection services, for use by scientists and industry members for the management of commercial fisheries and marine environments.