Principal Scientist, Clinical Biomarker, Immunology & Immuno-Oncology (Hematology) Legend Biotech USPrincipal Scientist, Clinical Biomarker, Immunology & Immuno-Oncology (Hematology)Somerset, New JerseyLeverage advanced single-cell technologies (e.g., scRNA-seq) to deeply profile immune cell compartments, particularly T-cell states and exhaustion markers, to inform patient stratification and biomarker hypotheses. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases.
Principal Bioinformatician Legend Biotech USPrincipal BioinformaticianSomerset, New JerseyTranslational Biomarker Analysis with multi-modality and multi-omics assays such as Bulk and Single cell RNA-seq, TCR/BCR-seq, WGS/WES, Amplicon-seq, ATAC-seq, ctDNA/liquid biopsy, Proteomics and cytokine profiling, spatial and multiplex imaging, Flow cytometry/CyTOF. Support translational biomarker discovery and validation including identification of pharmacodynamic (PD), predictive, prognostic, and response biomarkers; integrated analyses correlating biomarker data with: Clinical outcomes, PK/PD measurements, Safety for Patient stratification and Mechanism-of-action hypotheses.
Principal Product Designer - Wall Street Journal Enterprise Products News CorpPrincipal Product Designer - Wall Street Journal Enterprise ProductsNew York, NY$150,000–$200,000 / yearYou'll shape strategy with senior design, product, and business leadership, resolve the tension between enterprise requirements and consumer-grade craft, contribute to the enterprise patterns that live in our Index Design System, and mentor senior designers across both our professional and consumer brands. It is home to leading publications and products including the flagship Wall Street Journal, America's largest newspaper by paid circulation; Barron's, MarketWatch, Mansion Global, Financial News, Dow Jones Risk & Compliance and Dow Jones Newswires.
Principal | Digital Advisory Leader Buro Happold LtdPrincipal | Digital Advisory LeaderNew York, NY$200,000–$336,000 / yearBuilding on the success of our established Digital Advisory practices in the UK and Middle East, this role will play a critical part in shaping and scaling our US offering while contributing to Buro Happold's global strategy in building a market-facing consulting platform, originating executive-level opportunities, growing strategic accounts, and contributing directly to Buro Happold's commercial and strategic growth in the US and globally. This is a unique opportunity to build a market-leading advisory capability that helps clients unlock value through digital strategy, transformation, systems, solutions, data, and analytics across asset-intensive industries and the built environment.
Principal - Finance Operations (Dow Jones Technology) News CorpPrincipal - Finance Operations (Dow Jones Technology)New York, NY$165,000–$215,000 / yearAbout the Team: Technology Operations is in the middle of a significant operating-model transformation: shifting from initiative tracking to OKR-driven governance, driving a vendor-partnered efficiency transformation, consolidating location strategy around strategic hubs, and redesigning processes with automation and AI-enabled capabilities at the core. Working across Technology, Finance, Sourcing, Human Resources, the PMO, and external vendors, our team provides the operational discipline, financial stewardship, and governance needed to turn strategy into execution, enable better investment decisions, and build a simpler, more scalable operating model.
Principal Consultant - Semantic Data & AI Engineering CapcoPrincipal Consultant - Semantic Data & AI EngineeringNew York, NY$146,000–$183,000 / yearCapco is seeking a hands-on Principal Consultant to design and build semantic data solutions that make enterprise data usable by artificial intelligence, machine learning, analytics, and business applications. You will work across multiple project roles depending on client needs-serving as a semantic architect, knowledge-graph engineer, AI engineer, data engineer, technical lead, or client advisor.
NewLead Principal Technical Program Manager Oracle CorpLead Principal Technical Program ManagerNY$116,600–$264,100 / yearThis Lead Principal TPM will provide strategic and operational program leadership for a rapidly growing regional organization, with responsibility spanning Build & Deployment, production readiness, hardware lifecycle management, break-fix support, and automation across Oracle''s cloud infrastructure. Additional responsibilities include: Provide program leadership for Cloud Hardware Support and Server Operations initiatives across parts of North America, including Build & Deployment, production readiness, hardware lifecycle management, break-fix operations, and operational automation.
NewPrincipal Consultant, Cybersecurity CapcoPrincipal Consultant, CybersecurityNew York, NY$154,000–$192,000 / yearAs artificial intelligence continues to transform financial services, our team works closely with clients to develop secure and responsible AI adoption strategies, establish governance frameworks, manage emerging technology risks, and build trust in AI-enabled products and services. Experience across multiple cybersecurity domains, including Operational Resilience, Data Security, Identity & Access Management, Cloud Security, Digital Trust, Threat & Vulnerability Management, Security Governance, or Cyber Risk Management.
NewPrincipal Data and AI Architect Mitsui Sumitomo Insurance Company Of AmericaPrincipal Data and AI ArchitectWarren, NJRemote$180,000–$230,000 / yearArchitect and evolve MSIG USA's hybrid data platform built on Microsoft Fabric, Databricks, and Azure Data Lake (OneLake) - ensuring the platform supports batch, streaming, and real-time data workloads across all insurance domains. This is a role for a deeply technical, intellectually curious architect who is equally comfortable shaping long-term strategies and rolling up their sleeves to validate designs, prototype solutions, and guide engineering teams through complex delivery challenges.
NewPrincipal HR Business Partner Oracle CorpPrincipal HR Business PartnerNY$114,600–$234,600 / yearCANDIDATE QUALIFICATIONS: 12+ years of progressive Human Resources experience in a strategic business partnering capacity, with demonstrated expertise in workforce planning, organizational design and effectiveness, talent strategy, executive engagement, and leading through significant organizational change. Reporting to the Senior HR Director, you will serve as a trusted advisor and business accelerator, bringing strong business acumen, data-driven insights, change leadership, and HR expertise to help shape the continued growth and evolution of one of Oracle's fastest-growing businesses.
NewPrincipal AI Architect CleraPrincipal AI ArchitectNew York City, New YorkThis is a senior, principal-level architecture role at a well-established cybersecurity SaaS company, focused on shaping AI strategy and designing large-scale AI solutions across the organization. Provide technical leadership and direction across AI and ML initiatives, guiding cross-functional teams toward scalable, production-grade systems.
Principal Technologist - VMware CDW CorpPrincipal Technologist - VMwareNY$151,350–$211,870 / yearBachelor's degree and 10+ years of experience in a technical, pre-sales, or post-sale delivery role OR 14+ years of experience in a technical, pre-sales, or post-sale delivery role. The Principal Solution Architect is a field-based technical pre-sales role responsible for developing complex Hybrid Infrastructure solutions for CDW customers.
Principal Product Manager, Agentic Early Warning Services LLCPrincipal Product Manager, AgenticNew York City, NY$173,000–$230,000 / yearOperating with a high degree of autonomy in ambiguous and evolving conditions, the Principal Product Manager influences executives, technical teams, business partners, customers, and external stakeholders to make sound product decisions, manage risk, and deliver measurable customer and business value. Early Warning Services takes into consideration a variety of factors when determining a competitive salary offer, including, but not limited to, the job scope, market rates and geographic location of a position, candidate's education, experience, training, and specialized skills or certification(s) in relation to the job requirements and compared with internal equity (peers).
Principal Platform Software Engineer Oracle CorpPrincipal Platform Software EngineerNY$104,500–$234,600 / yearOracle maintains broad salary ranges for its roles in order to account for variations in knowledge, skills, experience, market conditions and locations, as well as reflect Oracle''s differing products, industries and lines of business. Articulate the technical characteristics of services and technology areas, and guide development teams to engineer and add premier capabilities to the Oracle Cloud service portfolio.
Principal Engineer (#002481 Multiple Positions Available) Wells Fargo & CoPrincipal Engineer (#002481 Multiple Positions Available)Iselin, NJ$191,000–$305,000 / yearMust possess 7 years of experience with at least 7 of the following technical skills: Experience with SAS or SQL; Experience with JAVA/J2EE; Experience with Agile methodologies; Experience with RESTful or SOAP web services; Experience with Anthill or Jenkins; Experience with Linux or UNIX; Experience with Spring, Spring Batch, Spring Boot, and performance tuning; Experience with Urbancode Deploy Experience in Jira; Experience with Application Logging Control tools; Experience with Maven; Oracle; or SVN; Experience in application performance, monitoring and optimization tools Blazemeter, Splunk, or AppDynamics; Experience in Application Programming Interface (API) or User Interface (UI) design and development; Experience in automations and unit testing using Jasmine, Karma, Selenium, Junit, or Jmeter; Experience in application or software security such as web application penetration testing, secure code review, or secure static code analysis. Wells Fargo Technology sets IT strategy; enhances the design, development, and operations of our systems; optimizes the Wells Fargo infrastructure footprint; provides information security; and enables continuous banking access through in-store, online, ATM, and other channels to Wells Fargos more than 70 million global customers.
Principal Consultant - Microbiology Oracle CorpPrincipal Consultant - MicrobiologyNY$71,200–$158,200 / yearWe are looking for an experienced Consultant to help design, configure, activate, and support the implementation of Oracle Health EHR (Millennium) solutions across Federal agencies including the Department of Defense, United States Coast Guard, Veterans Affairs and Indian Health Service. The Federal Consulting team is a group of hard-working, knowledgeable, passionate members who want to shape the electronic health records systems for active-duty service men and women, their beneficiaries, our Nation's Veteran's, American Indians, and Alaska Natives.
Principal Consultant -Gen Lab Oracle CorpPrincipal Consultant -Gen LabNY$71,200–$158,200 / yearWe are looking for an experienced Consultant to help design, configure, activate, and support the implementation of Oracle Health EHR (Millennium) solutions across Federal agencies including the Department of Defense, United States Coast Guard, Veterans Affairs and Indian Health Service. The Federal Consulting team is a group of hard-working, knowledgeable, passionate members who want to shape the electronic health records systems for active-duty service men and women, their beneficiaries, our Nation's Veteran's, American Indians, and Alaska Natives.
Principal Software Engineer Standard Template LabsPrincipal Software EngineerNew York City, New YorkWe’re looking for a Principal Software Engineer, Full-Stack AI to own the end-to-end technical vision for how intelligence is designed, built, and experienced across our platform - from data ingestion and model reasoning to APIs, user interfaces, and real-world operational impact. You will architect and ship production AI systems, build scalable backend and data platforms, and work across the stack to ensure AI capabilities are observable, trustworthy, and intuitive for enterprise users.
Principal Design System Designer Twin Health IncPrincipal Design System DesignerNYRemote$220,000–$230,000 / yearTwin has an ambitious vision to empower people to live healthier and happier lives, and to achieve this purpose, we need the very best people to enhance our cutting-edge technology and medical science, deliver the best possible care, and turn our passion into value for our members, partners and investors. Mission-Driven Leadership: A history of proactively taking the lead on complex initiatives, making the team around you stronger, and guiding projects across the finish line with speed, low ego, and a passion for building technology that genuinely helps people.
Principal Platform Engineer Metropolitan Transportation AuthorityPrincipal Platform EngineerNew York, NY$156,476–$184,692 / yearAs the MTA expands its reliance on digital workflows and automation, the demand for a dedicated engineering resource to support, enhance, and optimize enterprise-wide platforms has become essential toward reducing the MTA IT department's reliance on a managed service provider. Leads the technical security of the platform, monitoring and managing the configuration items, managing access controls/operating systems/ databases (CMDB), configuring MID servers, and taking proactive measures against potential cyber threats.