Bioinformatics & Data Scientist or Postdoctoral Researcher- Furman lab Buck InstituteBioinformatics & Data Scientist or Postdoctoral Researcher- Furman labNovato, CAFull timeGlobally recognized as a pioneer and leader in efforts to target aging — the number one risk factor for diseases including Alzheimer’s disease, Parkinson’s disease, cancer, macular degeneration, heart disease, and diabetes — the Buck seeks to help people live better longer. The Buck Institute for Research on Aging is seeking a full-time Bioinformatics and Data Scientist or Postdoctoral Researcher to join a collaborative research team focused on aging, multi-omics, computational biology, and translational data science.
Bioinformatics & Data Scientist Or Postdoctoral Researcher- Furman Lab Buck InstituteBioinformatics & Data Scientist Or Postdoctoral Researcher- Furman LabNovato, CA$80,000–$85,000 / yearGlobally recognized as a pioneer and leader in efforts to target aging - the number one risk factor for diseases including Alzheimer's disease, Parkinson's disease, cancer, macular degeneration, heart disease, and diabetes - the Buck seeks to help people live better longer. The Buck Institute for Research on Aging is seeking a full-time Bioinformatics and Data Scientist or Postdoctoral Researcher to join a collaborative research team focused on aging, multi-omics, computational biology, and translational data science.
Staff Research Scientist, AI Safety Chan Zuckerberg Biohub IncStaff Research Scientist, AI SafetyRedwood City, CA$241,000–$301,000 / yearSuccess requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology-developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide.
Scientist II, Scaling Lead Chan Zuckerberg Biohub IncScientist II, Scaling LeadSan Francisco, CA$138,000–$172,000 / yearThe ideal candidate is proactive, learns quickly, communicates well across teams, and enjoys contributing to both established workflows and the development of new experimental approaches across a wide range of disciplines, from optics, microscopy, and image processing to developmental, cell, and molecular biology. Work with the computation team to keep the image-processing pipeline (denoising, registration, fusion, deconvolution, segmentation, tracking) keeping pace with acquisition, addressing I/O, compute throughput, storage, and data retention so that raw acquisitions become analysis-ready results without a growing backlog.
Senior Scientist, In Vitro Cardiometabolic Disease Merck & Co IncSenior Scientist, In Vitro Cardiometabolic DiseaseSouth San Francisco, CA$131,400–$206,800 / yearRequired Skills: Assay Development, Biochemical Assays, Cell Culture Techniques, Drug Target Identification, High Content Screening, Immunoassays, Immunology, Metabolic Diseases, Molecular Biology, Neuroendocrinology, Primary Cell Culture, Protein Purifications, Quantitative Assay, Target Validation. The successful candidate will also possess a strong sense of intellectual curiosity to expand their technical expertise at the bench, as well as effective written and interpersonal communication skills to explain complex experiments and biological concepts to a broader scientific team.
Scientist/Sr Scientist, Protein Engineering EarliScientist/Sr Scientist, Protein EngineeringRedwood City, CA$110,000–$145,000 / yearDesign novel protein therapeutics-including cytokines, immune agonists, fusion proteins, bispecific constructs (multi-domain and 2A-based), leveraging structure-function knowledge and/or computational tools to guide engineering hypotheses. Design, develop, and execute functional assays in relevant cancer cell lines and primary human immune cells (PBMCs, T cells, NK cells, monocytes/macrophages) to evaluate candidate activity, potency, and selectivity.
Associate Principal Scientist, Discovery Oncology, Reverse Translation Merck & Co IncAssociate Principal Scientist, Discovery Oncology, Reverse TranslationSouth San Francisco, CA$159,600–$251,200 / yearRequired Skills: Biology, Cancer Biology, Cancer Therapy, Cell Biology, In Vitro Pharmacology, In Vitro Research, Molecular Biology, Oncology, Preclinical Research, Target Validation, Tumor Biology, Tumor Models. This role is an exciting opportunity to contribute to reverse translation efforts that leverage clinical insights, in vitro systems, and in vivo oncology models to identify novel therapeutic targets and elucidate mechanisms of tumor biology, disease progression, and therapeutic response.
Senior Scientist, In Vitro (Cardiometabolic Disease) Merck & Co IncSenior Scientist, In Vitro (Cardiometabolic Disease)South San Francisco, CA$131,400–$206,800 / yearThis role is well suited for an intellectually curious and driven scientist with a hypothesis-focused mindset who excels at integrating in vitro findings with preclinical in vivo and human-relevant insights to inform discovery-stage decisions. Demonstrated creativity and problem-solving ability in addressing complex biological questions using state-of-the-art in vitro approaches (reflected by publications and/or impactful internal contributions).
Scientist II, Genomic Core XAIRAScientist II, Genomic CoreSouth San Francisco, CA$124,000–$155,000 / yearYou will partner closely with Functional Genomics, Disease Biology, Automation, and Computational Biology teams to develop scalable sequencing strategies that support CRISPR-based perturbation studies, single-cell genomics, and other high-throughput discovery efforts. You will serve as a technical leader responsible for designing, developing, optimizing, and executing next-generation sequencing (NGS) workflows, with a primary focus on Illumina sequencing platforms, including MiSeq, NextSeq, and NovaSeq.
Scientist/Senior Scientist, Advanced Microscopy And Spatial Profiling California Life CompanyScientist/Senior Scientist, Advanced Microscopy And Spatial ProfilingSouth San Francisco, CA$160,000–$197,000 / yearCalico's highly innovative technology labs, its commitment to curiosity-driven discovery science, academic and industry partners, and vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs. Hands-on experience with proximity biotinylation techniques (i.e. BioID, APEX2, TurboID, BAR), including antibody conjugation strategies, fusion protein design, labeling kinetics optimization, and streptavidin-based enrichment.
Senior Scientist, Cardiac Modeling Insitro IncSenior Scientist, Cardiac ModelingSouth San Francisco, CA$156,000–$166,000 / yearIn this role, you will own the development and application of iPSC-derived cardiomyocyte (iPSC-CM) models to study the genetic and molecular underpinnings of cardiovascular disease - working at the intersection of human stem cell biology, cardiac physiology, and scalable experimental platforms to generate the datasets that fuel our ML-driven drug discovery efforts. We work hard to bring together diverse teams-grounded in a wide range of expertise and life experiences-and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices.
Senior Scientist, In Vitro ADME Aequor Technologies LLCSenior Scientist, In Vitro ADMEEmeryville, CAThe ideal candidate will have hands-on experience conducting in vitro ADME assays in a biopharmaceutical, pharmaceutical, or contract research organization setting, with strong technical expertise in LC-MS/MS, enzyme kinetics, cell-based assays, and data interpretation. - Conduct ADME screening studies, including but not limited to microsomal stability, hepatocyte stability, permeability, plasma protein binding, and related metabolism assays.
Scientist/Sr Scientist, Therapeutics Earli IncScientist/Sr Scientist, TherapeuticsRedwood City, CA$110,000–$145,000 / yearDesign novel protein therapeutics-including cytokines, immune agonists, fusion proteins, bispecific constructs (multi-domain and 2A-based), leveraging structure-function knowledge and/or computational tools to guide engineering hypotheses. Design, develop, and execute functional assays in relevant cancer cell lines and primary human immune cells (PBMCs, T cells, NK cells, monocytes/macrophages) to evaluate candidate activity, potency, and selectivity.
AI Scientist/Senior, Clinical & Molecular Genomics Modeling, BRAID Genentech IncAI Scientist/Senior, Clinical & Molecular Genomics Modeling, BRAIDSouth San Francisco, CA$127,500–$236,900 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Connect Molecular and Clinical Data: Create models that link heterogeneous molecular and cellular data with clinical outcomes, specifically focusing on prognostic, predictive, and pharmacodynamic biomarkers.
Senior Scientist I (In Vivo Pharmacology) Exelixis Inc.Senior Scientist I (In Vivo Pharmacology)Alameda, CA$127,500–$180,500 / yearEDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS: Education: BS/BA in Pharmacology, Cancer Biology, Molecular Cellular Biology or related field and a minimum of 7 years relevant experience; or, MS/MA in Pharmacology, Cancer Biology, Molecular Cellular Biology or related field and a minimum of 5 years relevant experience; or, PhD in Pharmacology, Cancer Biology, Molecular Cellular Biology or a closely related field and 0 years of relevant experience; or, Equivalent combination of education and experience. Extensive experience using in vivo tumor models for drug discovery with a proven track record in hands-on establishment, validation, and implementation of animal models for testing cancer therapies, including xenograft, syngeneic, genetically engineered mouse, orthotopic, PDX and humanized models to study biologic mechanisms.
Staff/Senior Staff, Bioinformatics Data Scientist Rezo TherapeuticsStaff/Senior Staff, Bioinformatics Data ScientistSan Francisco, CA$180,000–$260,000 / yearOur mission is to dramatically increase the success rate of drug development by building a disease-agnostic, fully-integrated, network biology platform that will redefine our understanding of human disease and ability to treat it. We are leveraging a unique integrated approach, combining capabilities in genetics, proteomics, structural biology and AI to generate deep biological insights and novel therapeutic approaches.
NewSenior Data Scientist, Compbio InsitroSenior Data Scientist, CompbioSouth San Francisco, CA$183,000–$194,000 / yearSynthesize Multimodal Insights: Draw insights from multimodal analyses (microscopy, spatial proteomics, bulk/single-cell RNA-seq, human cohort data) to uncover disease mechanisms and generate therapeutic hypotheses. We work hard to bring together diverse teams-grounded in a wide range of expertise and life experiences-and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices.
Scientist / Senior Scientist, Multiomics Applications Glyphic BiotechnologiesScientist / Senior Scientist, Multiomics ApplicationsBerkeley, CA$90,200–$147,600 / yearIn this role, you will independently execute and troubleshoot established sample preparation protocols across a broad range of biological inputs, generating high-quality data that supports ProSE performance benchmarking and Glyphic's broader multi-omic strategy, which combines ProSE, RNA-seq, DNA-seq, and Ribo-seq to identify neoantigens, biomarkers, and drug targets. Collaborate closely with proteomics, assay development, chemistry and data science teams to design experiments, interpret results, and guide project strategy — including cross-platform efforts (ProSE, RNA-seq, DNA-seq, ribosome profiling, and mass spectrometry).
ML Scientist I / II, Foundation Models for Life Sciences Lila Sciences IncML Scientist I / II, Foundation Models for Life SciencesSan Francisco, CA$176,000–$304,000 / yearFull-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. You will work on generative models spanning biological sequences, molecular structures, and multimodal experimental data, contributing to problem formulation, model design, training, evaluation, and integration into Lila''s closed-loop discovery engine.
Senior Scientist - Computational Protein Design Amgen Inc.Senior Scientist - Computational Protein DesignSouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.