Vice President, Biochemistry and Head of Early Discovery Projects Parabilis MedicinesVice President, Biochemistry and Head of Early Discovery ProjectsCambridge, MA$310,000–$340,000 / yearGuide projects from target evaluation and hit discovery through hit-to-lead and successful transition into late discovery, partnering with project teams to establish scientific strategy and execution plans, evaluate key scientific inflection points, recommend strategic pivots when needed, and drive critical go/no-go decisions. Mentor and develop early discovery project leaders, fostering scientific growth, strategic thinking, and strong program leadership capabilities across the organization while helping build the next generation of discovery leadership within Parabilis.
Distinguished Scientist, Group Head Biochemistry SanofiDistinguished Scientist, Group Head BiochemistryCambridge, MA$178,500–$257,833.33 / yearDeep expertise in biochemical assay development and characterization across multiple target classes (enzymes, protein-protein interactions, epigenetic targets, etc.). Provide strategic direction and scientific oversight for biochemistry activities supporting multiple drug discovery programs across diverse therapeutic areas.
NewSenior Research Associate (6 Month Contractor) – Biochemistry and Biophysics Monte Rosa Therapeutics, IncSenior Research Associate (6 Month Contractor) – Biochemistry and BiophysicsBoston, MassachusettsContractorThe successful candidate will have proven bench level expertise in establishing and performing a range of biochemical and biophysical assays to screen and characterize small molecule compounds and elucidate mechanism of action. The candidate should exhibit excellent communication and collaborative skills for working on cross-functional teams, as well as demonstrate a high degree of independence and organization.
Assistant Professor of Biochemistry Brandeis UniversityAssistant Professor of BiochemistryWaltham, MA$67,000–$85,000 / yearTeaching responsibilities will span the Biochemistry and Biology/HSSP programs and include an introductory and advanced introductory biochemistry class (BCHM 88 and BCHM 100), a project lab in protein biochemistry (BIOL 251), an elective course targeting Biochemistry majors (e.g., BIBC 126 Molecular Mechanisms of Disease), and an elective course appropriate for non-majors (e.g., CDSC 7. The pay offered to a selected candidate during hiring will be based on factors such as (but not limited to) the scope and responsibilities of the position, the candidate's work experience and education/training, internal peer equity, and applicable legal requirements.
Senior Scientist, Conjugation Biochemistry Flagship Pioneering IncSenior Scientist, Conjugation BiochemistryCambridge, MA$126,000–$181,500 / yearFlagship Labs 103, Inc. is a privately held early-stage company that is building advanced technological and computational platforms to pioneer the detection of cellular dynamics from minimally invasive biospecimens that can be leveraged to connect individuals to the most effective interventions to prevent onset and progression of disease. Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company's annual list of the World's Most Innovative Companies.
Adjunct Faculty- Biochemistry Massachusetts College of Pharmacy and Health SciencesAdjunct Faculty- BiochemistryBoston, MADuring recitations, the recitation instructor will assist students working through practice problems and administer quizzes that are provided by the recitation coordinator/lecture instructor. Advises and assists students through in-person office hours or scheduled appointments, by videoconference, phone, or email, and through other University-approved mechanisms.
Oligo Chemistry and Biochemistry Co-op (Fall 2026) Wave Life Sciences LtdOligo Chemistry and Biochemistry Co-op (Fall 2026)Cambridge, MAOur toolkit of RNA-targeting modalities includes editing, splicing, RNA interference and antisense silencing, providing us with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. Our diversified pipeline includes clinical programs in Duchenne muscular dystrophy, Alpha-1 antitrypsin deficiency and Huntington's disease, as well as a clinical program in obesity and a preclinical program in NASH/MASH.
Senior Research Associate (Oligo Chemistry & Biochemistry) Wave Life Sciences LtdSenior Research Associate (Oligo Chemistry & Biochemistry)Cambridge, MA$72,000–$98,000 / yearOur diversified pipeline is focused on our obesity, alpha-1 antitrypsin deficiency and PNPLA3 I148M liver disease programs and includes clinical programs for Duchenne muscular dystrophy and Huntington's disease, as well as several preclinical programs utilizing our versatile RNA medicines platform. Our toolkit of RNA-targeting modalities including RNAi silencing and RNA editing provides us with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology.
Adjunct Faculty - School of Pharmacy - Biochemistry Massachusetts College of Pharmacy and Health SciencesAdjunct Faculty - School of Pharmacy - BiochemistryBoston, MAThe School of Pharmacy-Boston seeks an adjunct faculty member to deliver high quality learning experiences and education for students in the Doctor of Pharmacy (PharmD) program. Advises and assists students through office hours or scheduled appointments, by videoconference, phone or email, and through other University-approved mechanisms.
NewSenior Research Associate (6 Month Contractor) - Biochemistry and Biophysics Monte Rosa Therapeutics IncSenior Research Associate (6 Month Contractor) - Biochemistry and BiophysicsBoston, MAThe successful candidate will have proven bench level expertise in establishing and performing a range of biochemical and biophysical assays to screen and characterize small molecule compounds and elucidate mechanism of action. The candidate should exhibit excellent communication and collaborative skills for working on cross-functional teams, as well as demonstrate a high degree of independence and organization.
LABORATORY TECHNICIAN BS-Biochemistry - Lau Lab Boston UniversityLABORATORY TECHNICIAN BS-Biochemistry - Lau LabBoston, MAThe salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, training and internal pay comparison. The candidate will work on NIH grant support investigations into how transposons mobilize and become expressed in model organism cells, like Drosophila, mouse and mosquito cells.
LABORATORY TECHNICIAN, BS-Biochemistry - Lau Lab Boston UniversityLABORATORY TECHNICIAN, BS-Biochemistry - Lau LabBoston, MA$41,643–$42,000Full timeThe candidate will work on NIH grant support investigations into how transposons mobilize and become expressed in model organism cells, like Drosophila, mouse and mosquito cells. Our group studies basic gene regulation mechanisms by small RNAs and the RNA interference pathway in model organisms.
Scientist-Principal Scientist, Protein Design & Structure Superluminal MedicinesScientist-Principal Scientist, Protein Design & StructureBoston, MassachusettsThe successful candidate will be a subject matter expert (SME) in membrane protein biochemistry, responsible for developing and implementing strategies to express, purify, and characterize challenging G-protein coupled receptors (GPCRs) to support structural biology, biophysics, and drug discovery programs. D. in Biochemistry, Molecular Biology, Biophysics, or a related field with 2+ years (Scientist), 5+ years (Senior Scientist), or 8+ years (Principal Scientist) of relevant experience; or a master’s or bachelor’s degree in a related field with commensurate industry experience.
Principal Scientist, Protein Design ModernaTXPrincipal Scientist, Protein DesignCambridge, MassachusettsThis role will lead the design, execution, and continuous advancement of high-throughput mammalian cell–based screening platforms that interrogate broadly applicable design principles for glycoprotein antigens, enabling antigen optimization, improved expression and durability across multiple programs, and rapid maturation of computationally designed candidates. The candidate in this position will work closely with and report to the Senior Director, Computational Design and In Vitro Selection, and will also work closely with the VP, Protein Design, as well as other members of Research, to advance novel candidates to the clinic, drive exploratory trials to inform the generation of improved vaccine antigens and explore new concepts for mRNA medicines.
Principal Scientist, Computational Protein Design ModernaTXPrincipal Scientist, Computational Protein DesignCambridge, MassachusettsThe Principal Scientist will work closely with and report to the Senior Director, Computational Design and In Vitro Selection, and will also work closely with the VP, Protein Design, as well as other members of Research, to advance novel candidates to the clinic, drive exploratory trials to inform the generation of improved vaccine antigens and explore new concepts for mRNA medicines. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
NewScientist II/Senior Scientist, Protein Sciences - Cell Binding Assays Manifold Bio IncScientist II/Senior Scientist, Protein Sciences - Cell Binding AssaysBoston, MA$125,000–$175,000 / yearManifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems. Develop, optimize, and qualify cell-based binding assays (flow cytometry / FACS, cell ELISA, and equilibrium binding formats) to characterize antibody-type molecules across a range of formats.
Senior Director, Pharmacokinetics, Dynamics, Metabolism and Bioanalysis, Protein Therapeutics Merck & Co IncSenior Director, Pharmacokinetics, Dynamics, Metabolism and Bioanalysis, Protein TherapeuticsBoston, MA$194,100–$305,600 / yearRequired Skills: ADME, Assay Development, Bioanalysis, Bioanalytical Assays, Bispecific Antibodies, Communication, Cross-Cultural Awareness, Drug Discovery Development, Drug Metabolism, Fast-Paced Environments, Immunology, Immunotherapy, Innovation, Ligand Binding Assay, Modeling Simulations, Monoclonal Antibodies, Oncology, People Leadership, Pharmacokinetics, PKPD Modeling, Protein Engineering, Results-Oriented, Scientific Leadership, Strategic Thinking, Therapeutic Proteins. The successful candidate will lead a group of principal investigators and subject matter experts and will be expected to collaborate cross-functionally with discovery biologics, nonclinical drug safety, translational medicine and therapeutic area colleagues to ensure robust program strategies from early discovery through to IND submission and beyond.
Scientist / Senior Scientist, Process Sciences and Innovation Strand Therapeutics IncScientist / Senior Scientist, Process Sciences and InnovationBoston, MA$120,000–$142,000 / yearBuilding on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Reporting to the Director of Process Development, this individual will serve as the technical lead for Process Sciences & Innovation, partnering closely with Analytical Development and Research, to identify, evaluate, and implement next-generation technologies that enhance process understanding, development efficiency, scalability, and product quality.
Research Associate, Protein Chemistry & Bioconjugation (6 MONTH CONTRACT) Ring TherapeuticsResearch Associate, Protein Chemistry & Bioconjugation (6 MONTH CONTRACT)Cambridge, MassachusettsThis is a highly collaborative, hands-on role requiring scientific independence and a strong focus on delivering well-characterized, high-quality protein and conjugate inputs to enable downstream assay development and candidate selection. Ring Therapeutics was founded in Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines (NASDAQ: GENB) were conceived and created.
Principal Scientist - Protein Formulation & Biophysical Characterization (High-Concentration Biologics) Pfizer IncPrincipal Scientist - Protein Formulation & Biophysical Characterization (High-Concentration Biologics)MA$106,000–$176,600 / yearDirect hands-on experience with biophysical/analytical characterization techniques and data interpretation including proficiency with a broad suite of techniques (DLS, DSC, DSF, SEC-MALS, NTA, CD, FTIR, fluorescence spectroscopy, rheology); ability to design and interpret multi-technique characterization studies. PhD in Pharmaceutics, Pharmaceutical Sciences, Biophysical Sciences, Biochemistry, Chemistry, Biomedical or Chemical Engineering, or related disciplines with 3-5 years relevant experience in biologics formulation, biophysics, or drug product development (industry experience preferred).
Senior Field Application Scientist, Protein XI Meso Scale Diagnostics LLCSenior Field Application Scientist, Protein XIBoston, MAThis salary range represents a general guideline as MSD considers other factors when presenting an offer of employment, such as scope and responsibilities of the position, external market factors, and the candidate's knowledge, skills, abilities, education and experience. The Senior FAS, Protein XI will provide advanced technical support, engage in hands-on method development during an initial rotation at MSD headquarters, and mentor junior members of the Field Applications team.
NewSenior Scientist, Protein Production Novartis AGSenior Scientist, Protein ProductionCambridge, MA$93,800–$174,200 / yearUnderstanding of protein characterization as well as protein-ligand interactions using biophysical methods (e.g., SPR, DSF, ITC, LC/MS).Demonstrated critical thinking and troubleshooting ability when handling challenging proteins such as aggregated proteins, multicomponent complexes, or membrane proteins. We are seeking a passionate, curious, and collaborative protein scientist to join our Protein Sciences group, an interdisciplinary team that has expertise in protein chemistry, enzymology, biophysics, NMR, X-ray crystallography, and electron microscopy.
Senior Scientist I - Mass Spectrometry/Protein Characterization UCB SASenior Scientist I - Mass Spectrometry/Protein CharacterizationCambridge, MA$117,600–$154,400 / yearFor this position you'll need the following education, experience and skills: Minimum Qualifications: PhD in related field and/or several years of industrial laboratory-based LC/MS experience (biochemistry, chemistry, molecular & cellular biology, or biophysics) + 6-12 years' experience, BS or MS + 12-18 years' experience. Working in a multidisciplinary team you will apply your expertise to complement the biophysical and biochemical characterizations of recombinant proteins and communicate to stakeholders across the US research organization.
Principal Scientist, Protein Design Moderna IncPrincipal Scientist, Protein DesignCambridge, MA$142,500–$256,500 / yearThis role will lead the design, execution, and continuous advancement of high-throughput mammalian cell-based screening platforms that interrogate broadly applicable design principles for glycoprotein antigens, enabling antigen optimization, improved expression and durability across multiple programs, and rapid maturation of computationally designed candidates. Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team.
Senior Director, Protein Analytics & Biophysics Generate BiomedicinesSenior Director, Protein Analytics & BiophysicsSomerville, MassachusettsSuccess in this role will require enterprise leadership: developing leaders and senior scientists, building an inclusive and high-accountability culture, partnering deeply across Protein Sciences, Prototyping, Technology, Data Sciences, Machine Learning, Biology, and CMC/Tech Ops, and translating an ambitious scientific vision into robust capabilities that improve decision quality, speed, and scale. The ideal candidate brings deep technical breadth, a quantitative mindset, and a clear point of view on how pooled assays, DNA/barcode-enabled readouts, synthetic biology, automation, microfluidics, advanced detection, and computational modeling can transform how protein therapeutics are evaluated.
Senior Principal Scientist I, Lab Head, Protein Engineering SanofiSenior Principal Scientist I, Lab Head, Protein EngineeringCambridge, MA$148.50–$214.50 / hourAs Lab Head, you will help drive the evolution of Sanofi's next-generation antibody engineering platforms by integrating structure-guided design, high-throughput experimental technologies, protein language models, computational modeling, and AI/ML-enabled engineering approaches into biologics discovery workflows. Serve as the Protein Engineering representative on cross-functional project teams, collaborating with Therapeutic Areas and partner functions to define engineering strategies, coordinate project activities, and support milestone progression.
Field Applications Scientist III (Boston) Takara Bio USA IncField Applications Scientist III (Boston)Boston, MA$120,000–$130,000 / yearHow you will make an impact: As a key member of Takara Bio USA's Field Applications team, you will play a pivotal role in advancing life science research by supporting the adoption and success of our innovative spatial biology and single-cell NGS technologies. What will you do: Engage with new and existing customers to educate, support and train on Takara Bio Spatial Biology products (Trekker and Seeker) and/or Takara Bio Single Cell NGS instrument platform (Shasta).
Inpatient Clinical Dietitian (Registered Dietitian Boston Medical CenterInpatient Clinical Dietitian (Registered DietitianBoston, MA$33.36–$42.52 / hourProvides nutritional care when consulted for several malnourished and/or critically ill patients; diagnoses malnutrition and documents in EHR using BMC approved malnutrition diagnostic criteria; utilizes the nutrition-focused physical exam to assess nutritional status; evaluates patient's nutritional needs and develops nutritional care plan; determines solutions for total parenteral nutrition and tube feedings when appropriate and submit to MD for approval as well as chart in the medical records. Additional advanced board certifications preferred for complex patient population: Certified Nutrition Support Clinician (CNSC), Certified Lactation Counselor (CLC), Pediatric Critical Care Nutrition (CSPCC), Certified Pediatric Nutrition (CSP), Certified Specialist in Obesity and Weight Management (CSOWM), Certified Diabetes Educator (CDE), or other advanced board certification.
Serif: Analytical Development Co-Op Flagship Pioneering Co-Op ProgramSerif: Analytical Development Co-OpCambridge, MassachusettsThe current Flagship ecosystem comprises 41 transformative companies, including: Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics, Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS). Current student enrolled in a Bachelors or Master’s program in Chemical Engineering, Biochemical Engineering, Bioengineering, Biomolecular Engineering, Chemistry, Biochemistry, Biomedical Engineering, Biophysics, Biotechnology, Molecular Biology, or a related field.
Principal Scientist, Nonclinical Drug Safety Program Discovery Merck & Co IncPrincipal Scientist, Nonclinical Drug Safety Program DiscoveryCambridge, MA$176,200–$277,300 / yearThey are responsible for 1) providing risk assessments for targets, 2) de-risking strategies for discovery programs and 3) collaborating with NDS staff at other sites to execute on the appropriate studies to support selection of therapeutic targets, and the identification and development of new drug candidates. The Discovery Program Leader is responsible for defining and overseeing the NDS strategy for programs in all modalities (including small molecules, peptides, biologics and ADC programs) from Target Identification through to the approval of First-In-Human enabling GLP toxicity studies.
Senior Research Associate, Analytical Technical Operations ModernaTXSenior Research Associate, Analytical Technical OperationsNorwood, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team.
Senior Director, Protein Analytics & Biophysics Generate Biomedicines IncSenior Director, Protein Analytics & BiophysicsSomerville, MA$210,000–$290,000 / yearSuccess in this role will require enterprise leadership: developing leaders and senior scientists, building an inclusive and high-accountability culture, partnering deeply across Protein Sciences, Prototyping, Technology, Data Sciences, Machine Learning, Biology, and CMC/Tech Ops, and translating an ambitious scientific vision into robust capabilities that improve decision quality, speed, and scale. The ideal candidate brings deep technical breadth, a quantitative mindset, and a clear point of view on how pooled assays, DNA/barcode-enabled readouts, synthetic biology, automation, microfluidics, advanced detection, and computational modeling can transform how protein therapeutics are evaluated.
Grants and Finance Administrator Brandeis UniversityGrants and Finance AdministratorWaltham, MAJob Description: Tracking information for sponsored accounts including updating budgets as needed, projecting personnel and non-personnel expenses, monitoring accounts, reviewing account records for accuracy, reconciling all accounts to Workday and generating reports monthly for the Principal Investigators. Work with personnel in the Division of Science administrative groups as well as Sponsored Programs Accounting, Office of Research Administration, Procurement, Payroll, A&S Dean, and other offices to correct errors or overages.
Senior Research Associate, Analytical Technical Operations Moderna IncSenior Research Associate, Analytical Technical OperationsNorwood, MA$74,000–$118,400 / yearWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team.
Field Applications Scientist III (Boston) Takara Bio—HomeField Applications Scientist III (Boston)Boston, MassachusettsHow you will make an impact: As a key member of Takara Bio USA’s Field Applications team, you will play a pivotal role in advancing life science research by supporting the adoption and success of our innovative spatial biology and single-cell NGS technologies. Job Title: Field Applications Scientist III (Boston) Reports to: Manager, Field Applications Support FLSA Class: Exempt Learn more about our company and how we support you: Takara Bio USA (TBUSA) empowers life science discovery.
NewScientist - Proteomics Dana-Farber Cancer Institute IncScientist - ProteomicsBOSTON, MA$80,000–$95,900 / yearWe strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. Candidates with diverse mass spectrometry experience are encouraged to apply, with particular interest in individuals who bring expertise in laboratory automation, instrument operations, systems oversight, and proteomics workflow development.
Research Lab Technician II - OHNS Cancer Research Mass General BrighamResearch Lab Technician II - OHNS Cancer ResearchBoston, MassachusettsCarries out a broad range of technically advanced research activities and procedures; evaluates conclusions and has considerable latitude to modify or devise methods and techniques as necessary to achieve desired results; typically supervises technical and sometimes administrative elements of the research unit. Preferred qualifications include prior experience with mouse tumor models or cancer biology research, as well as familiarity with molecular biology techniques such as Western blotting, nucleic acid extraction, flow cytometry, immunofluorescence, and immunohistochemistry.
Research Lab Technician II - OHNS Cancer Research Brigham and Women's HospitalResearch Lab Technician II - OHNS Cancer ResearchBoston, MA$24.28–$39.43 / hourCarries out a broad range of technically advanced research activities and procedures; evaluates conclusions and has considerable latitude to modify or devise methods and techniques as necessary to achieve desired results; typically supervises technical and sometimes administrative elements of the research unit. Preferred qualifications include prior experience with mouse tumor models or cancer biology research, as well as familiarity with molecular biology techniques such as Western blotting, nucleic acid extraction, flow cytometry, immunofluorescence, and immunohistochemistry.