34 Results for

Biochemistry Jobs in Brookline, MA

Jobs

Lexington, MA30+ days ago

$28–$32 Per Hour

Protein expression: assist with routine mammalian expression of our therapeutic molecules to support ongoing studies, assess novel drug candidates through transient expression with CHO and HEK cells, establish stable cell-lines of new drug candidates when necessary. With a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue.

Lexington, MA30+ days ago

$28–$32 Per Hour

With a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. Support protein production efforts, including expression in mammalian systems, purification to achieve high quality reagents using FPLC, affinity, ion-exchange, and SEC chromatography, and continuous optimization of production methods for novel biomolecules.

Boston, MA30+ days ago

$41,643–$42,000

The candidate will work on NIH grant support investigations into how transposons mobilize and become expressed in model organism cells, like Drosophila, mouse and mosquito cells. Our group studies basic gene regulation mechanisms by small RNAs and the RNA interference pathway in model organisms.

BEDFORD, MA30+ days ago

Full-time

Required QualificationsPhD in Immunology, Protein Engineering, Biochemistry, Molecular Biology, or a related field, with 7+ years of relevant industry experience in biologics or protein therapeutics discovery (4+ years for Senior Scientist level). The successful candidate will combine deep expertise in protein engineering, antibody and multispecific formats, and immuno-oncology biology with strong scientific leadership and hands-on execution.

Natick, Massachusetts30+ days ago

$125,000–$155,000 Per Year

You will be responsible for: Analyzing scientific information to address microbiological, biological, and material science matters related to microbiological contamination root cause analysis, forensics, and product development, but also including a wide range of topics from medical devices and pharmaceuticals to consumer products and electronics. A strong theoretical and practical knowledge of various microbiological and biological assays (such as nucleic acid amplification tests, immunoassays, bacterial culture, protein quantification, and enzyme assays) and how material interactions can impact those techniques.

Waltham, MA17 days ago

$50–$53 Per Hour
Contractor

Key Responsibilities Perform characterization testing of gene therapy samples to determine and quantify host cell proteins using solid-phase enhanced sample preparation and LC-MS analytical techniques commonly used in proteomics (i.e. proteomic profiling using DDA or DIA, targeted quantitation using MRM or PRM). Basic Qualifications Masters degree in Analytical Chemistry, Biochemistry, or a related discipline with 2-4 years of relevant biotechnology or pharmaceutical industry experience, preferably performing impurity monitoring using LC-MS or proteome/HCP profiling or Doctorate degree with 1-3 years of relevant experience in proteomics.

Waltham, MA17 days ago

$40–$49 Per Hour
Contractor

Key Requirements and Technology Experience: Skills-MASS SPECTROMETR, automation liquid handler, Method development and troubleshooting Master’s degree in Analytical Chemistry, Biochemistry, or a related discipline with 2-4 years of relevant biotechnology or pharmaceutical industry experience, preferably performing impurity monitoring using LC-MS or proteome/HCP profiling or Doctorate degree with 1-3 years of relevant experience in proteomics. Key Responsibilities: Perform characterization testing of gene therapy samples to determine and quantify host cell proteins using solid-phase enhanced sample preparation and LC-MS analytical techniques commonly used in proteomics (i.e. proteomic profiling using DDA or DIA, targeted quantitation using MRM or PRM).

Boston, MA9 days ago

$170,000–$190,000 Per Year

Every team member plays a crucial role in driving the future of biotech research, building the world's most efficient sequencing engine that operates overnight and scales globally. This role is heavily bioinformatics-focused, emphasizing deep domain expertise and the building of scalable products over general software platform skills.

Cambridge, MA30+ days ago

Develop and oversee ligand-binding immunoassays (ELISA, MSD, Luminex or similar platforms) for the detection of translated proteins and anti-drug or anti-protein antibodies, including screening, confirmatory, and neutralizing antibody assays in accordance with regulatory guidance. You will be a subject matter expert in nucleic acid and protein bioanalysis, working to generate critical data that informs decision-making across preclinical and clinical development.

Norton, MA30+ days ago

Full-time

Perform routine and non-routine microbiological assays (bioburden, TOC, endotoxin, conductivity), with increasing complexity, to support critical utility samples, in-process samples, and product release, following established SOPs Maintain up-to-date training records, adhere to the testing schedule, and ensure the timely completion of all assignments to support the seamless operation of QC activities and uphold the department's commitment to meeting project timelines and quality metrics Assist in the maintenance of laboratory equipment and inventory to ensure smooth laboratory operations Ensure data is submitted timely; may qualify as a data reviewer to ensure timely and efficient data availability. Collaborate with QC and cross-functional teams to ensure seamless quality control operations and to support the collective company goals Participate in inspection readiness activities as well as supporting onsite audits and inspections, as needed.

Newton, Massachusetts30+ days ago

$99,450–$177,000 Per Year
Full-time

The ideal candidate should have demonstrated wet lab experience working independently in a biophysics, chemistry, biochemistry, or molecular biology laboratory, have exceptional attention to detail, be creative, and be able to critically analyze data and communicate results to the team. Responsibilities: • Support and spearhead the method development and optimization of novel molecular biology assay schemes for spatial omic applications including molecular barcoding, fluorophore marking, nucleic acid hybridization, amplification and sequencing techniques, and probe library preparation.

Norton, Massachusetts30+ days ago

£74,880–£93,600

Perform routine/non-routine analytical (HPLC/UPLC) and/or microbiological assays for raw materials, in-process samples, product release, and stability studies following SOPs. R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering.

Waltham, MA30+ days ago

Full-time

This LC–MS-focused role involves generating and interpreting data on oligonucleotide exposure, stability, metabolism, protein binding, and structural integrity to answer DMPK-relevant questions and link analytical findings with PK/PD and biological activity. Exposure & Disposition: Apply LC–MS and other methods to assess oligonucleotide–protein interactions, binding, and disposition, interpreting how stability, metabolism, and chemical modifications influence systemic and tissue exposure.

Boston, Massachusetts30+ days ago

$60–$65 Per Hour

Agreeing to the Atrium Terms and Conditions, includes permission to use the email address and mobile phone number you provide during the application process or throughout the duration of your prospective or actual employment to notify you of job openings, profiles, articles, news, and other employment-related information, as well as to notify you of special promotions or additional products and services offered by us or our affiliates and partners. The Cell Hub is dedicated to the maintenance, tracking, quality control (QC), and production of cell biomass for critical assays and high throughput screenings, as well as the development of innovative techniques for large-scale production of complex cell models.

Boston, MA30+ days ago

$67,500–$70,000

Demonstrated experience (ideally publications or preprints) in one or more of the following areas is highly desirable: Tissue culture, including flow cytometry, toxicity assays and generation of stable cell lines. Working with our unique archive of clinical data and samples, the successful candidate will apply a range of approaches including protein biochemistry and cell biology to model systems and patient samples.

Watertown, MA30+ days ago

$115,000–$200,000 Per Year

Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Perform and interpret quantitative proteomics data analyses using software such as Skyline, MaxQuant, DIANN, and Spectronaut; generate clear, data-driven reports for cross-functional stakeholders.

Waltham, MA30+ days ago

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. In this role, you’ll play a key part in analyzing a diverse range of molecules generated through fermentation and enzyme catalysis, while working closely with a collaborative team of scientists across disciplines.

Cambridge, MA30+ days ago

You will also pioneer the integration of state-of-the-art AI techniques into real-world biologics pipelines, working closely with wet-lab scientists, bioinformaticians, protein engineers, and drug discovery program teams . Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

New!

Cambridge, MA1 day ago

The role involves designing experiments to uncover structural determinants of signal transduction, collaborating across molecular biology, computational modeling, and cell biology, and presenting findings at conferences and in publications. Responsibilities include conducting bench research, applying for funding, contributing to grant and manuscript writing, mentoring lab members, and supporting overall lab operations.

Boston, Massachusetts30+ days ago

There are two primary functions of this position: 1) Culturing human iPSCs and differentiating them in neurons and glia cells, 2) Characterization of cultures with biochemistry, microscopy and molecular biology (Protein extraction Western blotting, ELISA, immunostaining and microscopy, RNA and DNA extraction, PCR and qPCR, genome editing). Overview: The Department of Neuroscience is a basic science department that focuses on cutting-edge research in the areas of neurological disease.

Boston, Massachusetts30+ days ago

The ideal candidate will be able to help evolve Monte Rosa’s hit identification and hits-to-leads endeavors through embracing novel assay technologies, enhancing overall process and actively drive internal and external partnerships. Overview: Monte Rosa Therapeutics is seeking a passionate Contractor High Throughput Cellular Assays with the experience to implement and run complex cellular assays for a 6-month contract.

New!

Boston, MA1 day ago

$47,400–$51,800 Per Year

The ideal candidate has a Bachelor's in a biological or chemical science, laboratory experience (preferably in mammalian cell culture, biochemistry, or molecular biology), and strong organizational and communication skills. Responsibilities include conducting experiments in chemistry, biochemistry, and cell biology, such as ligand-binding analyses, protein purification, and cell-based assays.

Boston, MA30+ days ago

$140,000–$188,000 Per Year

Demonstrated expertise applying analytical techniques for protein analysis, including binding ELISAs, chromatographic purity assays, cell-based potency assays, extended characterization, routine compendial assays, and analytical comparability in support of commercialization. We have a robust pipeline of novel product candidates designed to target multiple key biological pathways to drive an effective anti-tumor response, including angiogenesis modulation, immune activation within the tumor microenvironment, and reduction of tumor-driven immunosuppression.

Boston, MA30+ days ago

Requires a Bachelor's degree from an accredited university or college in Medial Technology or Clinical Laboratory Science which includes successful completion of a supervised course of clinical internship in an approved hospital laboratory, or a Bachelor's degree in an applied science (Chemistry, Biology, Biochemistry). CERTIFICATES, LICENSES, REGISTRATIONS REQUIRED: Certification by American Society of Clinical Pathologists (ASCP) or National Credentialing Agency (NCA) or equivalent agency as a Medical Technologist, Clinical Laboratory Scientist, Medical Laboratory Technician, or specialty certification is preferred.

Cambridge, MA30+ days ago

Full-time

The DECODE platform has been validated through four strategic partnerships with leading pharmaceutical companies—Bristol Myers Squibb, Genentech, Eli Lilly, and Pfizer—representing over $4.5 billion in disclosed total deal value and $185 million in upfront payments received to date. The successful candidate will bring deep expertise in biologics CMC development, demonstrated success building teams and processes in both early‑stage and mature organizations, and a strong track record of technology transfer and management of external manufacturing organizations.

Boston, MA30+ days ago

As a Senior Scientist Immunology overseeing the design and execution of in vitro and in vivo mechanistic, proof-of-concept and safety studies, provide scientific and technical expertise in immune cell biology, and support regulatory filing with authoring of technical reports. · Establish and validate in vitro models of autoimmune diseases; support the design and execution of in vivo experiments such as PK, tox, dosing.

Natick, Massachusetts30+ days ago

The successful candidate will work closely with senior scientists and cross‑functional teams to execute high‑quality DEL and SELEX screening projects, analyze data, and support timely delivery of results to internal teams and external clients. Overview: DNA‑encoded library (DEL) and SELEX (Systematic Evolution of Ligands by EXponential enrichment) technologies are rapidly expanding drug discovery platforms within the IVBU at WuXi AppTec.

Lexington, MA30+ days ago

$65–$74 Per Hour

With a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. Our group exploits multidisciplinary approaches in protein sciences and protein engineering, to better the understanding of the biochemical, biophysical, and structural functional properties of the biomolecules within the TGF- superfamily that drive the signaling pathway.

Cambridge, MA30+ days ago

$270,000–$300,000

This highly visible role will be accountable for the preclinical bioanalytical strategy, biomarker strategy, data quality, and regulatory readiness, ensuring successful EDIT-401 IND submission and Clinical Trial execution. As the Senior Director, Bioanalytical and Biomarker Development, you will: Lead assay development, qualification, validation, and execution for measuring drug product components, immunogenicity, biomarkers, and other analytes in biological matrices.

Cambridge, MA30+ days ago

$128,420–$155,600 Per Year

Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Waltham, MA30+ days ago

$58,000–$65,000

Develop, perform, interpret, and troubleshoot a broad range of in vitro assays including immune cell profiling, cytokine profiling, functional assays using primary cells, as well as cytotoxicity/apoptosis assays using primary and/or cultured cells. Its service platform integrates preclinical studies with innovative animal models, CRISPR-based gene editing, and animal supplies, with the current focus on immuno-oncology and oncology.

Boston, Massachusetts30+ days ago

1. Sales Behaviors: · Respond to customer requests in a timely manner and leverage the appropriate overlays (Tech Serv, North America Marketing (NAM), Cust Serv, Field Support Scientist (FSS), Global Clinical Collaborations Manager (GCCM), Clinical Account Consultant (CAC), Strategic Collaborations Management Team (SCMT), Strategic Product Manager (SPM), Strategic Business Unit (SBU), Elite Access, R&D etc.) as necessary to ensure customer satisfaction. · Works closely with Regional/Associate/sales manager to develop opportunity-based pricing strategies at accounts (quotes, purchasing contracts with discount schedules, freezer programs and stockroom/consignment).

Boston, Massachusetts14 days ago

Incorporate the Core ESI Principles in their position (check in with yourself, listen with empathy, enhance self-esteem, look for the good, with discernment, encourage diverse perspectives and use courage and compassion to say what needs to be said). 2. In collaboration with the senior management team, broadly monitor regional performance, developing clear action plans to optimize team efficiencies.

Devens, MA14 days ago

$74,672–$87,152

This role will focus on cryogenics, cold-chain transportation, single-use systems, materials-related technical evaluations, and lab-based studies supporting commercial biopharmaceutical manufacturing operations. Minimum Bachelor’s degree with 2+ years of industry experience, or Master’s degree in Chemical Engineering, Biochemical Engineering, Chemistry, Biochemistry, Biology, or a related scientific discipline.

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Biochemistry Jobs in Brookline, MA

Research Associate Co-Op, Protein Biochemistry Keros Therapeutics

Research Associate Co-Op, Protein Biochemistry/Engineering Keros Therapeutics

LABORATORY TECHNICIAN, BS-Biochemistry - Lau Lab Boston University

Principal/ Senior Scientist – T Cell Engager & Multispecific Protein Engineering PharmaEssentia U.S.A.

Scientist (Ph. D.) Exponent Inc.

Scientist I Integrated Resources, Inc

Scientist I Pyramid, Inc

Bioinformatics Scientist Vivo HealthStaff

Senior Scientist, Bioanalytical Sciences CEDENT

Microbiologist LanceSoft Inc

Senior Scientist Bruker

Quality Control Microbiologist RD Partners

Scientist / Senior Scientist, Bioanalytical LC–MS – Oligonucleotide Alloy Therapeutics

Research Scientist – Cell Biologist, High Throughput Human Biology (Contract) Vertex Pharmaceuticals

Postdoctoral Associate, Amyloidosis Center, Boston University Chobanian Avedisian School of Medicine Boston University

Senior Scientist, Targeted Proteomics Kymera Therapeutics

Research Associate, Analytical Chemistry Manus

Principal Scientist (AI/ML) - Predictive modeling, design and optimization for therapeutic antibodies Bristol Myers Squibb

HMS - Postdoctoral Fellow in BCMP, Blacklow Lab Harvard University

Research Technician, Neuroscience Tufts University

Contractor High Throughput Cellular Assays (6 Months) Monte Rosa Therapeutics, Inc

Administrative Research Technician (Walensky Lab) Dana-Farber Cancer Institute

Principal Analytical Scientist, CMC Compass Therapeutics

Assistant Supervisor Laboratory (Hematology)($5 000 Sign-on Bonus external candidates only) Boston Medical Center

Vice President, Head of CMC Repertoire Immune Medicines

Senior Scientist Immunology CEDENT

DEL Platform Scientist II WuXi AppTec

Contract Senior Research Associate, Protein Science Keros Therapeutics

Senior Director, Bioanalytical and Biomarker Development Editas Medicine

Scientist - Discovery Protein Engineering Bristol Myers Squibb

Pharmacology Research Associate Biocytogen

Client Representative - Boston Promega

Manager, Regional Sales Promega

Assistant / Associate Scientist - MSAT Materials & Cryogenics SOKOL GxP Services

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