Lead, Senior, or Principal Biologist SWCA Environmental ConsultantsLead, Senior, or Principal BiologistHalf Moon Bay, California$97,344–$127,196 / yearCandidates are also encouraged to consider SWCA’s Total Rewards package, which includes a competitive benefits package ( https://www.swca.com/careers/benefits-wellness/ ), forward-thinking workplace flexibility, outstanding corporate culture, award-winning career development, and more. We are seeking a candidate who is looking to develop or continue a long-term consulting career that combines high-level technical expertise, business acumen, and the potential for leadership.
Field Biologist (Field Based) Environmental Resources Management, Inc.Field Biologist (Field Based)Walnut Creek, CAPart timeAs the largest global pure play sustainability consultancy, we partner with the world’s leading organizations, creating innovative solutions to sustainability challenges and unlocking commercial opportunities that meet the needs of today while preserving opportunity for future generations. ERM is hiring Field Biologists to perform biological surveys, nesting bird surveys and construction monitoring in Northern California (San Francisco, Santa Rosa, Santa Cruz, Oakland, East Bay).
Computational Biologist NewLimit IncComputational BiologistSouth San Francisco, CA$130,000–$170,000 / yearYou will work closely with experimentalists and computational scientists to maintain core infrastructure, assess emerging analysis tools, and build robust software solutions that improve efficiency, scalability, and reliability. Experience analyzing and interpreting single-cell or multi-omics datasets (e.g., scRNA-seq, multiome, scATAC-seq), with hands-on exposure to perturbation screens preferred.
Managing Consultant, Biologist (Senior Level) Environmental Resources Management, Inc.Managing Consultant, Biologist (Senior Level)Walnut Creek, CAFull timeAs the largest global pure play sustainability consultancy, we partner with the world’s leading organizations, creating innovative solutions to sustainability challenges and unlocking commercial opportunities that meet the needs of today while preserving opportunity for future generations. An employee’s pay position within this range will be based on several factors including, but not limited to, relevant education, qualifications, certifications, experience, skills, geographic location, performance, shift, travel requirements, sales or revenue-based metrics, and business or organizational needs.
Quantitative Biologist Arcadia Science LLCQuantitative BiologistEmeryville, CA$150,000–$200,000 / yearWe are seeking a Quantitative Biologist to join our Validation team with strong expertise in using computational analyses across modalities and biological scales to extract meaning from complex data, identifying the limits of existing analytical approaches, and developing new ones to address them. Your contributions will be instrumental in validating existing tools at Arcadia, shaping how we design and interpret experiments, identifying potential assets, and building robust analytical infrastructure that scales across the team.
Computational Biologist II, CellxState BiohubComputational Biologist II, CellxStateSan Francisco, CaliforniaAt the core of our current efforts is multiDPS (Multimodal Dynamic Pooled Screening), a high-throughput platform that integrates custom microscopy, automation, CRISPR screening and molecular profiling to map and predict dynamic cell states. We also create large reference datasets that can be mined and reused by the entire community for discovery, like our OpenCell project that maps protein localization and interactions ( https://opencell.czbiohub.org/ ).
Computational Biologist II, CellxState Chan Zuckerberg Biohub IncComputational Biologist II, CellxStateSan Francisco, CA$153,000–$210,100 / yearAt the core of our current efforts is multiDPS (Multimodal Dynamic Pooled Screening), a high-throughput platform that integrates custom microscopy, automation, CRISPR screening and molecular profiling to map and predict dynamic cell states. We also create large reference datasets that can be mined and reused by the entire community for discovery, like our OpenCell project that maps protein localization and interactions ( https://opencell.czbiohub.org/ ).
Field Biologist (Field Based) ERM GroupField Biologist (Field Based)Walnut Creek, CAFull timeAs the largest global pure play sustainability consultancy, we partner with the world’s leading organizations, creating innovative solutions to sustainability challenges and unlocking commercial opportunities that meet the needs of today while preserving opportunity for future generations. ERM is hiring Field Biologists to perform biological surveys, nesting bird surveys and construction monitoring in Northern California (San Francisco, Santa Rosa, Santa Cruz, Oakland, East Bay).
Wildlife Biologist (On-Call) AECOMWildlife Biologist (On-Call)San Jose, CAExperience surveying and monitoring for special-status and protected species that may occur in Central California, such as nesting birds, California condor, California red-legged frog, California tiger salamander, tidewater goby, western pond turtle, Swainson's hawk, Burrowing owl, Yellow billed cuckoo, Snowy plover, Marbled murrelet, Monterey dusky footed woodrat, Steelhead, Green sturgeon, Coho salmon, Western bumble bee, pallid bat, Smith's blue butterfly, monarch, and others. We invite you to bring your bold ideas and big dreams and become part of a global team of over 50,000 planners, designers, engineers, scientists, digital innovators, program and construction managers and other professionals delivering projects that create a positive and tangible impact around the world.
Principal Environmental Professional or Biologist Montrose Environmental Group IncPrincipal Environmental Professional or BiologistOakland, CA$150,000–$180,000 / yearOur scientists, engineers, field teams and consultants apply systems thinking that unites science, data and practical expertise to deliver solutions that strengthen our clients' resilience, mitigate risk and protect the air, water and soil that sustain communities, while uncovering responsible paths forward for planet and progress. Excellent written and verbal communication skills, ability to oversee and provide quality assurance for complex technical documents, as well as make presentations, including interviews for competitive proposals.
Principal Consultant, Biologist/Regulatory Specialist, Power and Renewables ERM International Group LtdPrincipal Consultant, Biologist/Regulatory Specialist, Power and RenewablesWalnut Creek, CA$104,236–$156,352 / yearAs the largest global pure play sustainability consultancy, we partner with the world's leading organizations, creating innovative solutions to sustainability challenges and unlocking commercial opportunities that meet the needs of today while preserving opportunity for future generations. Our diverse team of world-class experts supports clients across the breadth of their organizations to operationalize sustainability, underpinned by our deep technical expertise in addressing their environmental, health, safety, risk and social issues.
Desert Tortoise Authorized Field Biologist (Field Based) ERM International Group LtdDesert Tortoise Authorized Field Biologist (Field Based)Walnut Creek, CAWho We Are: As the largest global pure play sustainability consultancy, we partner with the world's leading organizations, creating innovative solutions to sustainability challenges and unlocking commercial opportunities that meet the needs of today while preserving opportunity for future generations. An employee's pay position within this range will be based on several factors including, but not limited to, relevant education, qualifications, certifications, experience, skills, geographic location, performance, shift, travel requirements, sales or revenue-based metrics, and business or organizational needs.
Desert Tortoise Field Biologist (Field Based) ERM International Group LtdDesert Tortoise Field Biologist (Field Based)Walnut Creek, CA$74,825–$96,901 / hourWho We Are: As the largest global pure play sustainability consultancy, we partner with the world's leading organizations, creating innovative solutions to sustainability challenges and unlocking commercial opportunities that meet the needs of today while preserving opportunity for future generations. An employee's pay position within this range will be based on several factors including, but not limited to, relevant education, qualifications, certifications, experience, skills, geographic location, performance, shift, travel requirements, sales or revenue-based metrics, and business or organizational needs.
Field Biologist (Field Based) ERMField Biologist (Field Based)Walnut Creek, CaliforniaIn addition to nesting birds, expertise should include more than one of the following species: Southwestern Willow Fly Catcher, Burrowing Owl, Spotted Owl, Eagles/raptors, Least Bell’s Vireo, California Gnatcatcher, Yosemite toad, CA Red-Legged Frog, Yellow Legged Frog subspecies, Pacific Fisher, San Bernardino Kangaroo Rat, Stephen’s Kangaroo Rat, Western Pond Turtle or Desert Tortoise. As the largest global pure play sustainability consultancy, we partner with the world’s leading organizations, creating innovative solutions to sustainability challenges and unlocking commercial opportunities that meet the needs of today while preserving opportunity for future generations.
As-Needed Field Biologist - Bay Area DudekAs-Needed Field Biologist - Bay AreaOakland, California$24–$50 / hourOur employees are unified by a singular commitment to supporting projects that address key societal issues, such as the transition to renewable energy, infrastructure hardening and repair, environmental protection, and community resilience. Today, we are a 100% employee-owned firm supporting clients nationwide and delivering projects that improve and protect the built and natural environments of communities throughout the United States.
Mid-level As-needed Terrestrial Biologist - Northern California Helix Environmental Planning IncMid-level As-needed Terrestrial Biologist - Northern CaliforniaCARemote$35–$45 / hourDrafting or leading preparation of due diligence, focused survey, habitat assessment, biological technical reports, biological sections of NEPA/CEQA documents, annual reports, restoration plans and jurisdictional delineation reports, including analyzing impacts and identifying mitigation measures. HELIX Environmental Planning, Inc. (HELIX), a growing, employee-owned California-based environmental consulting and planning firm, is seeking a motivated Mid-level As-needed Terrestrial Biologist based in the Sacramento, Central Valley, or Bay Area regions.
Staff Natural Resources Biologist Black & Veatch Holding CoStaff Natural Resources BiologistWalnut Creek, CA$108,944–$193,154 / yearIn this role as a Staff Natural Resources Biologist, you will have the opportunity to: Work with a dynamic team within an established global infrastructure and engineering company, collaborating with a team of natural resources biologists and other multi-discipline environmental consultants and engineers to lead and support a wide range of terrestrial biological desktop and field studies and support related permitting activities in the Western US with a focus on California. As a full-service environmental consulting practice, services include impact assessment and planning, regulatory compliance and permitting, wetland and floodplain analysis, waterbody and water quality assessment, air quality permitting and management, environmental remediation, site due diligence, environmental noise assessment, pollution prevention planning, and climate action solutions.
Principal Consultant, Biologist/Regulatory Specialist, Power and Renewables ERMPrincipal Consultant, Biologist/Regulatory Specialist, Power and RenewablesWalnut Creek, California$111,000–$160,905 / yearAs the largest global pure play sustainability consultancy, we partner with the world’s leading organizations, creating innovative solutions to sustainability challenges and unlocking commercial opportunities that meet the needs of today while preserving opportunity for future generations. Our diverse team of world-class experts supports clients across the breadth of their organizations to operationalize sustainability, underpinned by our deep technical expertise in addressing their environmental, health, safety, risk and social issues.
Computational Biologist Verge GenomicsComputational BiologistSan Francisco, California5 years of experience working in applied computational biology and integration of multi-omic datasets (RNA-seq, genotyping, clinical), with 2 years in a startup environment, 2 years of experience in relevant areas of translational science , demonstrating a deep understanding of target identification, biomarker discovery, and/or patient stratification, Proven ability to implement, evaluate, and/or create computational methodologies that leverage machine learning, statistics, and AI for biological research and discovery, Fluency with state of the art in systems biology workflows, including off-the-shelf biological databases and computational biology tools, Track record of bridging biological domain knowledge with computational approaches to solve real scientific problems. Experience in building and evaluating machine learning models on biological data , ideally with transformer-based models (e.g., scGPT, Geneformer, ESM, ProtBERT), with a deep understanding of feature selection, model interpretability, Professional experience with AI workflows, including natural language processing (NLP), retrieval-augmented generation (RAG), embeddings, vectorization of diverse data types, and working with large language models (e.g., GPT), Demonstrated experience with model evaluation and experimental design in a scientific context, including setting up appropriate benchmarks and controls.
Project Manager - Biologist/Ecologist Stantec IncProject Manager - Biologist/EcologistWalnut Creek, CATask duties may include managing environmental permitting efforts, providing quality control on biological reviews and reports, managing technical study support for siting and licensing of other energy production and transmission projects, environmental impact analysis support, and CEQA/NEPA support, and coordination/management for environmental projects. Manage multi-discipline program or project schedules, deliverables, budgets, staff, and the project record, and bring program/project schedules, budgets, and scopes of work to successful completion.
Computational Biologist - Fully Remote MercorComputational Biologist - Fully RemoteSan Francisco, CaliforniaRemote$70–$100 / hourDesign challenging computational problems using domain-specific scientific software libraries like libRoadRunner , Tellurium , or SBML-based tools . Develop problems that test AI systems' ability to implement complex multi-step scientific workflows and strategic reasoning.
Computational Biologist Stanford UniversityComputational BiologistStanford, CA$116,966–$150,114 / yearResearch and assist in the development and implementation of innovative technical solutions to meet research needs, including machine learning algorithms, text and image processing techniques, API programming, custom full-stack applications, automated web scraping, and crowdsourcing pipelines. The candidate will have experience designing and delivering technical training, workshops, or educational content to diverse audiences, with strong communication skills and the ability to translate complex computational concepts for researchers with varying technical backgrounds.
Consulting Senior Associate, Biologist (Entry Level) Environmental Resources Management, Inc.Consulting Senior Associate, Biologist (Entry Level)Walnut Creek, CAFull timePrimarily this position will provide desk-based biological expertise to large-scale utility projects in northern California (the location for this position is negotiable, but ideally northern California).We seek an individual to join the ERM’s planning, biological and environmental compliance team for an ongoing contract with a large California utility to support their Vegetation Management operations and maintenance activities. As the largest global pure play sustainability consultancy, we partner with the world’s leading organizations, creating innovative solutions to sustainability challenges and unlocking commercial opportunities that meet the needs of today while preserving opportunity for future generations.
AI Intern - Fall Start Upside Foods IncAI Intern - Fall StartEmeryville, CAUPSIDE Foods has raised more than $600 million in funding from a diverse group of leading U.S. and global investors, including top-tier venture capital firms, sovereign investment funds, strategic food and agriculture partners, and prominent technology and sustainability investors. You'll partner with biologists to ensure your features honor metabolic reality, iterate with manufacturing engineers to translate raw sensor streams in algorithms and push models across scales, and ship crisp visualizations that make complex kinetics intuitive for non‑experts.
Managing Consultant, Environmental Compliance Manager ERMManaging Consultant, Environmental Compliance ManagerWalnut Creek, California$94,990–$124,245 / yearAs the largest global pure play sustainability consultancy, we partner with the world’s leading organizations, creating innovative solutions to sustainability challenges and unlocking commercial opportunities that meet the needs of today while preserving opportunity for future generations. Our diverse team of world-class experts supports clients across the breadth of their organizations to operationalize sustainability, underpinned by our deep technical expertise in addressing their environmental, health, safety, risk and social issues.
Senior Software Engineer, Data Platform Profluent IncSenior Software Engineer, Data PlatformEmeryville, CA$170,000–$220,000 / yearThis role is ideal for an engineer who enjoys building robust data systems: secure ingestion pipelines, well-structured warehouses, reliable data models, access controls, auditability, and infrastructure that makes complex scientific data usable at scale. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.
Technical Director - Biological Resources GHD Group Pty LtdTechnical Director - Biological ResourcesConcord, CA$147,000–$245,000 / yearCommunity of Practice Management: Contribute strongly on a strategically significant area to a community of practice in a defined area of expertise or consulting, or lead on an area of expertise or consulting practice, to contribute to thought leadership and to develop innovative practice among colleagues. The ideal candidate must be recognized as an industry leader and have significant experience in wildlife biology, botany and/or wetland science; business development; contributing to growth of practice areas; overseeing the environmental review process; and winning and leading projects of importance.
Associate Laboratory Director Natera IncAssociate Laboratory DirectorSan Carlos, CA$158,200–$197,800 / yearThe Technical Supervisor is responsible for ensuring: appropriate test method selection; adequate method verification to determine the accuracy and precision of the test; enrollment of the laboratory in a CMS-approved proficiency testing (PT) program for the test performed; PT samples are tested in accordance with the CLIA requirements; PT results are returned within the time frames established by the PT program; PT reports are reviewed by the appropriate staff; corrective action plans are followed when PT results are found to be unacceptable or unsatisfactory; quality assessment and quality control programs are established and maintained; acceptable analytical test performance is established and maintained for each test system; remedial actions are taken and documented when significant deviations from the laboratory's established performance characteristics are identified, and patient test results are reported only when the system is functioning properly; personnel have been appropriately trained and demonstrate competency prior to testing patient specimens; policies and procedures are established for monitoring personnel competency in all phases (preanalytic, analytic, and postanalytic) of testing to assure the ongoing competency of all individuals who perform testing; remedial training or continuing education needs are identified, and training provided; and an approved procedure manual is available to all personnel. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other.
Sr Staff Data Scientist, Virtual Biology Initiative BiohubSr Staff Data Scientist, Virtual Biology InitiativeRedwood City, New YorkDeep expertise in at least one of: (a) imaging data—microscopy, cell phenotyping, spatial biology, and the data characteristics of image-based biological measurement; or (b) genomics data—bulk and single-cell sequencing, functional genomics, epigenomics, transcriptomics, spatial biology, and/or multi-omics. We need scientific leaders who can work at this frontier: people who understand biological measurement deeply, think creatively about data representations, sampling, and tokenization strategies, and can translate that thinking into data representations that enable novel training architectures.
Sr Staff Data Scientist, Virtual Biology Initiative, AI Research Chan Zuckerberg Biohub IncSr Staff Data Scientist, Virtual Biology Initiative, AI ResearchCA$241,000–$331,100 / yearDeep expertise in at least one of: (a) imaging datamicroscopy, cell phenotyping, spatial biology, and the data characteristics of image-based biological measurement; or (b) genomics databulk and single-cell sequencing, functional genomics, epigenomics, transcriptomics, spatial biology, and/or multi-omics. We need scientific leaders who can work at this frontier: people who understand biological measurement deeply, think creatively about data representations, sampling, and tokenization strategies, and can translate that thinking into data representations that enable novel training architectures.
Senior Computational Scientist â Systems Biology & NextâGen Data Engineering CalliereSenior Computational Scientist â Systems Biology & NextâGen Data EngineeringUnion City, CaliforniaYouâll join a tight-knit team of scientists and engineers decoding huge multiâomic datasets to uncover patterns that actually change patient outcomes. If youâre driven by the idea of building tools that help decode biology at scale and you thrive where data meets diagnostics, this is your stage.
Regional Biology Lead BKFRegional Biology LeadRedwood City, CA$153,691–$187,845Support clients in need of environmental permitting, including but not limited to Incidental Take Permits, Habitat Conservation Plan Drafting and consistency analyses, Clean Water Act 401 and 404 permits, California Coastal Commission permits, and CDFW Section 1600 permitting. In the event a recruiter or agency submits a resume or candidate without a previously signed agreement and a specific solicitation for the position or other approved engagement request for the position with BKF Engineers, BKF Engineers reserves the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency.
NewMember of the Technical Staff, Phenomics and High-Throughput Biology ConquestMember of the Technical Staff, Phenomics and High-Throughput BiologyPalo Alto, CaliforniaA big part of this role is workflow automation in the truest sense: figuring out what a skilled human currently does at the bench, understanding why it works, and then re-engineering it so a robot does it reliably at scale. You'll design experiments in oncology cell models, push them toward high-throughput, and work directly with our computational and AI team to make sure the data we generate is worth learning from.
Scientist 3 - CVRM Discovery Biology Genentech IncScientist 3 - CVRM Discovery BiologySouth San Francisco, CA$103,400–$192,000 / yearIn this lab-based role, you will design and execute experiments to explore central and peripheral mechanisms of metabolism, translate complex datasets into actionable biological hypotheses, and work closely with colleagues across research biology, computational biology, functional genomics, drug discovery, and therapeutic project teams. Our group combines in vitro and in vivo experimental biology with human genetics, functional genomics, AI/ML-enabled discovery, and translational insight to identify druggable regulators of disease biology and champion high-confidence targets through early drug discovery.
Research Associate, Discovery Biology Assembly Biosciences IncResearch Associate, Discovery BiologySouth San Francisco, CA$87,000–$91,300 / yearSpecific responsibilities include, but are not limited to: Executing in vitro experiments to identify and characterize small molecules inhibiting viral infection Optimizing and validating cell-based or biochemical assays to support ongoing discovery projects In collaboration with senior research member, make detailed observations, analyze data, and interpret results Effectively supporting multiple projects and learning new techniques to support novel exploratory discovery work, as needed. Qualifications Include: Sc./M.S. or equivalent degree in Cell Biology, Molecular Biology, Virology, or relevant scientific discipline Minimum of 2 - 3 years of relevant experience in industrial or academic settings, preference given to experience in a drug discovery setting Strong expertise in assay development, cell biology, and molecular biology techniques, e.g.
Executive Director, Computational Systems Biology Revolution Medicines IncExecutive Director, Computational Systems BiologyRedwood City, CA$265,000–$331,000 / yearThe individual will lead a team of computational biologists and bioinformaticians focused on acquisition, organization, and analysis of large multi-omics data sets, using both public and proprietary data sources, that will help inform treatment strategies and guide patient stratification for a growing pipeline of RAS(ON) and targeted oncology therapeutics. The company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Postdoctoral Fellow - Computational Biology & Medicine - Jhunjhunwala Lab Genentech IncPostdoctoral Fellow - Computational Biology & Medicine - Jhunjhunwala LabSouth San Francisco, CA$110,000–$120,000 / yearJoin Genentechs Computational Sciences Center of Excellence as a Postdoctoral Fellow, where youll conduct cutting-edge research at the intersection of computational biology and oncology. Research responsibilities will include (but not limited to) multi-omics analysis of bulk and single-cell sequencing data, developing deep learning models, and experimental design to test and validate hypotheses.
NewResearch Scientist, Life Sciences Experimental Biology Anthropic PBCResearch Scientist, Life Sciences Experimental BiologySan Francisco, CA$300,000–$320,000 / yearDesign, execute, and iterate on the experimental programs at the core of the team''s research: molecular biology, biochemistry, protein and nucleic acid characterization, high-throughput functional screens, and the assay development that makes new questions answerable. This research continues many of the directions our team worked on prior to Anthropic, including: GPT-3, Circuit-Based Interpretability, Multimodal Neurons, Scaling Laws, AI & Compute, Concrete Problems in AI Safety, and Learning from Human Preferences.
New2026 Summer/Fall Intern - AI/ML for Systems Biology Genentech Inc2026 Summer/Fall Intern - AI/ML for Systems BiologySouth San Francisco, CA$40–$50 / hourThe AI for Biology & Translation (AIBT) department, housed within the Computational Sciences Center of Excellence, operates at the cutting-edge intersection of artificial intelligence and translational genomics. By translating raw biological data into actionable therapeutic targets, the Systems Biology group within AIBT plays a critical role in advancing next-generation medicine from the bench to the bedside.
Senior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT) Genentech IncSenior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT)South San Francisco, CA$147,800–$274,400 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Scale frontier AI models to massive datasets working at the intersection of deep learning and engineering challenges, focusing on system design, architectural choices, and scalability, in collaboration with engineering and MLOps teams.
Senior Scientist, Computational Biology (Multimodal Data Integration) Genentech IncSenior Scientist, Computational Biology (Multimodal Data Integration)South San Francisco, CA$130,800–$242,800 / yearThe Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in delivering more innovative and transformative medicines for patients worldwide. You will develop computational frameworks and advanced statistical models in partnership with other computational biologists to creatively address complex scientific questions from Research and Translational Medicine and to deliver actionable biological insights and therapeutic strategies.
Executive Director, Computational Systems Biology Revolution MedicinesExecutive Director, Computational Systems BiologyRedwood City, CaliforniaThe individual will lead a team of computational biologists and bioinformaticians focused on acquisition, organization, and analysis of large multi-omics data sets, using both public and proprietary data sources, that will help inform treatment strategies and guide patient stratification for a growing pipeline of RAS(ON) and targeted oncology therapeutics. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Scientist, Mechanistic Biology General ProximityScientist, Mechanistic BiologySan Francisco, CAYour responsibilities will include designing and executing mechanistic studies on hit compounds, dissecting signaling pathways to map compound mechanism of action, interrogating protein-protein interactions, preparing and analyzing NGS libraries, and developing and deploying functional cell-based assays to characterize novel pharmacology. Strong experience with: Cellular and molecular biology, including extensive experience with mammalian cell line work and associated assays, stable cell line generation (lentiviral and CRISPR-based systems), co-IP/pull-down assays, RNA-seq, global proteomics, flow cytometry, plasmid design/cloning, etc.
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related) Amgen IncAssociate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related)South San Francisco, CA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Principal Scientist, Cancer Biology General ProximityPrincipal Scientist, Cancer BiologySan Francisco, CAPre-clinical characterization and mechanistic elucidation of small-molecule drug candidatesMechanistic studies of cancer cell signaling and PTM analysisPhenotypic assay development for cancer drug discovery (low to high throughput)Small molecule drug development campaigns (hit discovery, hit validation, dose-response studies, SAR and MOA studies)Proficiency in: Managing a team of exceptional scientists and research associatesTarget/indication selectionAnimal models of cancer (GEMM, orthotopic, xenograft models), in vivo study design, and PK/PD interpretationManaging CROs for in vitro and in vivo studiesGrant writingNice to have:Experience navigating IND-enabling studies and working on teams that have successfully advanced research to the clinicExperience working at the interface of cancer biology and chemistry Familiarity or experience with PROTAC/next-gen IPM technologiesExperience with PPI techniques (e.g., BRET, APEX/BioID, AlphaScreen etc.)BenefitsStrong equity incentives. Strong experience with:Cellular and molecular biology, including cancer cell line work and associated assays, stable cell line generation (lentiviral and CRISPR-based systems), co-IP/pull-down assays, RNA-seq, global proteomics, flow cytometry, plasmid design/cloning etc.
Scientist/Sr. Scientist, Chemical Biology General ProximityScientist/Sr. Scientist, Chemical BiologySan Francisco, CAYour responsibilities will include: supervising synthetic efforts with our CROs, designing, performing, and analyzing in cellulo assays, designing and optimizing first-in-class bifunctional molecules, collaborating with our Drug Discovery and IP team on patent applications, providing input for mechanistic studies on lead drug molecules, and spearheading forays into new disease areas. Experience with chemical biology techniques such as mammalian cell culture and cell-based assays (e.g., cytotoxicity assays, transfections, stable cell line generation, co-immunoprecipitation), and PPI assays (e.g., BRET, APEX/BioID, AlphaScreen).
Developmental Biology Faculty in Otolaryngology-Head & Neck Surgery Stanford UniversityDevelopmental Biology Faculty in Otolaryngology-Head & Neck SurgeryStanford, CA$196,000–$214,000 / yearThe Department of Otolaryngology - Head & Neck Surgery at Stanford University seeks a developmental biologist (PhD or MD) with interest in neurosensory biology to join the OHNS Department as Assistant Professor, Associate Professor or Professor in the University Tenure Line (UTL), University Medical Line (UML) or Non-Tenure Line-Research (NTL-R). We are particularly interested in candidates who have a strong background in stem cell biology and experience with combining multiple approaches, such as in vitro organoid methodologies and in vivo models, to investigate the development of sensory organs of the head and neck and to understand disorders of the hearing, vestibular, and/or olfactory systems.
Scientist II, Structural Biology Revolution Medicines IncScientist II, Structural BiologyRedwood City, CA$132,000–$166,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Interact with interdisciplinary teams (including chemists, computational chemists, biologists, project teams, and management) and clearly articulate structural data in a broader drug discovery context.
Scientist II, Structural Biology Revolution MedicinesScientist II, Structural BiologyRedwood City, CaliforniaThe company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Interact with interdisciplinary teams (including chemists, computational chemists, biologists, project teams, and management) and clearly articulate structural data in a broader drug discovery context.