Principal Scientist, Cancer Pharmacology, Translational Research Revolution MedicinesPrincipal Scientist, Cancer Pharmacology, Translational ResearchRedwood City, California$190,000–$238,000 / yearAs a Principal Scientist in the Cancer Pharmacology team within the Translational Research group, in the Biomedical Discovery Research Department, you will: Provide scientific and strategic leadership for RAS(ON) inhibitor programs by translating mechanistic insights in RAS biology into impactful pharmacology strategies and translational study plans. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Senior Machine Learning Scientist I, Drug Discovery Analytics Revolution MedicinesSenior Machine Learning Scientist I, Drug Discovery AnalyticsRedwood City, California$229,000–$269,000 / yearThe company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Computational Clinical Scientist II, Clinical Bioinformatics Revolution MedicinesComputational Clinical Scientist II, Clinical BioinformaticsRedwood City, CaliforniaThe company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Integrate multiple data sources including circulating tumor DNA, patient enrollment data, molecular profiling (RNA/DNA sequencing outputs), multiplex immunohistochemistry to identify and validate new biomarkers for candidate drugs.
Scientist II, Analytical Development VaxcyteScientist II, Analytical DevelopmentSan Carlos, CA$146,000–$171,000 / yearThis role performs routine and non-routine analytical assays using modern analytical techniques, supports method optimization and troubleshooting efforts, and contributes to continuous improvement initiatives with moderate supervision while partnering effectively with cross-functional teams. Strong hands-on experience with multiple analytical techniques, such as UV-Vis, HPLC, CE, SDS-PAGE, icIEF, liquid chromatography, mass spectrometry, enzyme kinetics, colorimetric and fluorescent plate-based assays, ELISA, Western Blot, and PCR.
Associate Scientist II, Analytical Development, Raw Materials (Contract) VaxcyteAssociate Scientist II, Analytical Development, Raw Materials (Contract)San Carlos, CA$51–$56 / hourPerform routine and non-routine analytical testing using modern analytical methods (e.g., LCMS, HPLC/UPLC, SEC, CE, UV-Vis, electrophoresis, plate-based assays, and other biochemical or biophysical techniques). This role will perform routine and non-routine analytical assays using modern analytical techniques and will contribute to method optimization, troubleshooting, and continuous improvement initiatives under supervision.
Scientist I, Analytical Development VaxcyteScientist I, Analytical DevelopmentSan Carlos, CA$129,000–$151,000 / yearThis role performs routine and non-routine analytical assays using modern analytical techniques, supports method optimization and troubleshooting efforts, and contributes to continuous improvement initiatives with moderate supervision while partnering effectively with cross-functional teams. Strong hands-on experience with multiple analytical techniques, such as liquid chromatography (H/UPLC) and/or mass spectrometry (LC-MS), CE, SDS-PAGE, icIEF, enzyme kinetics, colorimetric and fluorescent plate-based assays, ELISA, Western Blot, and PCR.
NewScientist II, Cancer Genomics, Clinical Biomarker Development Revolution MedicinesScientist II, Cancer Genomics, Clinical Biomarker DevelopmentRedwood City, CaliforniaThe company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Experienced in the interrogation of DNA sequence data derived from tumor tissue, such as gene-panel, whole-exome or whole-genome data and downstream analytics (clonality estimates, copy number variation, chromosomal instability, mutational signatures, etc).
NewHybrid | Senior Pharmaceutical R&D Scientist — $65–$105/hour 24-MagHybrid | Senior Pharmaceutical R&D Scientist — $65–$105/hourSan Francisco, CaliforniaWe are sharing a specialised full-time opportunity for senior pharmaceutical and biotechnology R&D professionals with substantial experience across drug discovery, preclinical development, translational science, clinical development, regulatory affairs, or CMC. PhD or PharmD in a pharmaceutically relevant discipline such as Medicinal Chemistry, Organic Chemistry, Pharmacology, Molecular Biology, Pharmaceutical Sciences, Toxicology , or a related field.
Computational Scientist II - Single Cell Genomics Dawar ConsultingComputational Scientist II - Single Cell GenomicsSouth San Francisco, CaliforniaThis role will involve analyzing large-scale sequencing datasets, developing computational pipelines, and collaborating with multidisciplinary teams to generate biological insights that support drug discovery. Analyze and interpret large-scale single-cell sequencing datasets (scRNA-seq) generated from high-content perturbation experiments.
Image Data Scientist Dawar ConsultingImage Data ScientistSouth San Francisco, CaliforniaThe Translational Safety, Pathology – Digital Pathology team is seeking an Image Data Scientist to support the development of computational image analysis workflows for digital histopathology. Develop and implement image analysis pipelines for digital pathology / histopathology images using classical image processing, ML, and deep learning techniques.
Research Specialist / Sr Scientist, Assay Sciences, Discovery Pharmacology Altos LabsResearch Specialist / Sr Scientist, Assay Sciences, Discovery PharmacologySan Francisco, CA$129,500–$166,000 / yearAs a Research Specialist or Sr Scientist of Assay Sciences, Discovery Pharmacology team, your primary focus will be supporting the needs of development and operation of a wide range of analytical and bioassays within the Drug Discovery and Development (3DS) division of Altos. You'll be taking manual assays and turning them into super-efficient, automated processes-think moving from a bench to high-throughput screening with automated gear.
Principal Scientist, CMC Analytical Development - Commercial Products Denali TherapeuticsPrincipal Scientist, CMC Analytical Development - Commercial ProductsSouth San Francisco, CA$159,000–$207,000 / yearAs the product transitions into routine commercial production and Denali pursues marketing applications in additional countries, we are seeking a Principal Scientist to join our Large Molecule Analytical Development Team to serve as a Commercial Analytical Lifecycle Lead. The Commercial Analytical Lifecycle Lead is expected to partner closely with peer Late Stage Analytical Development and Bioassay Development Leads responsible for driving successful analytical transfer & registration of a second-source manufacturing and QC site.
Associate Scientist, Analytical Development Denali TherapeuticsAssociate Scientist, Analytical DevelopmentSouth San Francisco, CA$106,000–$138,000 / yearDenali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. Key Accountabilities/Core Job Responsibilities: Assist in the development of chromatography, electrophoresis, spectroscopy and mass spectrometry-based analytical methods to be used for product release, stability, and characterization testing.
Associate Scientist Discovery Proteomics Amgen Inc.Associate Scientist Discovery ProteomicsSouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Responsibilities will include: Execute and optimize established proteomics workflows, including sample preparation, peptide fractionation, liquid chromatography, and mass spectrometry acquisition for discovery and targeted approaches such as DIA, TMT, label-free DDA and PRM.
Senior Scientist - Experimental Protein Design For Target Discovery Amgen Inc.Senior Scientist - Experimental Protein Design For Target DiscoverySouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role you will build and lead high-throughput platforms for binder generation, translating computational protein designs into experimentally validated minibinders and antibodies across diverse pre-discovery targets.
Senior Scientist - Translational Safety & Risk Sciences (Tsrs) Amgen Inc.Senior Scientist - Translational Safety & Risk Sciences (Tsrs)South San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Principal Scientist - Data Insights & Hypothesis Design TempusPrincipal Scientist - Data Insights & Hypothesis DesignRedwood City, CA$150,000–$200,000 / yearData Engineering & Scale Architecture: Proven experience collaborating directly with data engineering and platform teams to build large-scale relational databases, design advanced SQL data models, and support the robust infrastructure needed to create and deploy massive, production-grade models. Multi-Omic & NGS Modalities: Deep expertise executing multi-omic analyses across a diverse spectrum of high-throughput sequencing applications and biotechnologies, including specialized NGS modalities such as single-cell sequencing, immunomics, metagenomics, and varied sequencing platforms.
Principal Scientist, Inflammation Amgen Inc.Principal Scientist, InflammationSouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Familiarity with small and large molecule drug discovery, mechanism of action studies, ELISA, MSD, and flow cytometry-based immune cell profiling, single-cell RNA sequencing (scRNA-Seq), CRISPR/Cas9, and omics data analysis experience a plus.
Senior Clinical Laboratory Scientist (Sat - Tue 6am - 4:30pm) 4x10 Schedule - Onsite Guardant HealthSenior Clinical Laboratory Scientist (Sat - Tue 6am - 4:30pm) 4x10 Schedule - OnsiteRedwood City, CaliforniaAs a Senior Clinical Laboratory Scientist, you are responsible for performing high complexity laboratory testing (next generation sequencing) on patient specimens, performing quality control and quality assurance procedures, and reporting patient results. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics.
NewSenior Bioinformatics Scientist RocheSenior Bioinformatics ScientistPleasanton, CaliforniaPreferred: You have a PhD in Bioinformatics, Computational Biology, Statistics, or a related field with 2 years of industry experience in clinical diagnostics or related domain or a Masters degree in Bioinformatics, Computational Biology, Statistics, or a related field with 5 years of industry experience in clinical diagnostics or a related domain. Contribute bioinformatics expertise throughout the assay development lifecycle, including initial sequencing, validation, and production implementation, by developing and maintaining analytical tools and pipelines for processing diagnostic data from tumor, germline, and cell-free DNA samples.