Senior/Principal Machine Learning Scientist, Perturbation Biology, AI Biology & Translation (AIBT) Genentech IncSenior/Principal Machine Learning Scientist, Perturbation Biology, AI Biology & Translation (AIBT)South San Francisco, CA$147,800–$274,400 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. We are seeking a highly motivated and collaborative Senior/Principal Machine Learning Scientist to join the Perturbation Biology group in the Department of AI for Biology & Translation (AIBT) in Genentech Research and Early Development (gRED).
Computational Scientist (Biology) AxiomComputational Scientist (Biology)San Francisco, CaliforniaThis creates a compounding loop: deeper customer understanding shapes the data we generate; better data improves frontier models, Axiom’s fine-tuned models, and our agentic infrastructure; stronger models and tooling expand the capabilities we can offer; and those capabilities are forward deployed into pharma's drug discovery workflows, where scientists use them to solve the highest value drug discovery problems. Analyze high-content imaging and transcriptomic data from primary human hepatocytes and multicellular hepatic systems, including phenotypes related to mitochondrial dysfunction, cholestasis, lipid accumulation, lysosomal stress, ER stress, cytotoxicity, and cellular morphology.
Scientist, Assays and Biology - San Carlos, California BeOne Medicines AGScientist, Assays and Biology - San Carlos, CaliforniaSan Carlos, CA$136,600–$170,700 / yearGeneral Description: At BeOne Institute, we extend BeOne's execution strength with a dedicated innovation engine, bringing agility and scientific depth to transform uncertainty into actionable and high-impact therapeutic opportunities. Strong hands-on expertise in mammalian cell biology, including experience with genetic perturbation approaches such as CRISPR-based knockout/knock-in, RNAi-mediated knockdown, or related methods.
Senior Scientist, Computational Biology XAIRASenior Scientist, Computational BiologySouth San Francisco, CA$136,000–$170,000 / yearYou will work closely with wet-lab scientists, AI/ML scientists, automation engineers, and disease biology teams to develop scalable perturbation workflows, implement new technologies, and drive high-quality data generation and experimental innovation across multiple therapeutic areas. Deep expertise in single-cell RNA sequencing analysis with substantial hands-on experience in Perturb-seq or CRISPR-based perturbation screen data, including thorough familiarity with the full processing stack from raw reads to interpretable outputs.
Senior Principal Machine Learning Scientist, AI Biology & Translation (AIBT) Genentech IncSenior Principal Machine Learning Scientist, AI Biology & Translation (AIBT)South San Francisco, CA$202,800–$376,600 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. This role is ideal for a researcher with a strong track record in machine learning, sequence modeling, regulatory genomics, and representation learning who is excited about advancing the frontier of AI for biology.
Senior Scientist, Target Discovery & Biology - Functional Genomics Amgen Inc.Senior Scientist, Target Discovery & Biology - Functional GenomicsSouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Scientist I, Disease Biology Altos LabsScientist I, Disease BiologySan Francisco, CA$134,700–$172,700 / yearAbility to maintain cooperative working relationships with a broad range of people, including staff colleagues, lab members, faculty, outside agencies and collaborators, and the community. In this role you will develop physiologically relevant in vitro and ex vivo disease models and integrate these with in vivo studies to identify interventions that reverse disease-associated cell states.
Senior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT) Genentech IncSenior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT)South San Francisco, CA$147,800–$274,400 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Scale frontier AI models to massive datasets working at the intersection of deep learning and engineering challenges, focusing on system design, architectural choices, and scalability, in collaboration with engineering and MLOps teams.
Scientist 3, Cell Therapy - T Cell Biology Genentech IncScientist 3, Cell Therapy - T Cell BiologySouth San Francisco, CA$103,400–$192,000 / yearThe Cell Therapy department within Genentech Research and Early Development (gRED) is seeking a motivated scientist to help develop novel cell therapies for patients with intractable diseases. Evaluate engineered T cells using appropriate phenotypic and functional assays, including proliferation, cytokine production, cytotoxicity and persistence-related measurements.
New(Senior / Principal) Scientist, Cell Biology (Night Shift) Capable Labs(Senior / Principal) Scientist, Cell Biology (Night Shift)San Francisco, CaliforniaDeep hands-on experience developing and running cell-based assays in cell biology, pharmacology, molecular biology, chemical biology, neuroscience, bioengineering, screening, or a closely related area. Lead the design, execution, and optimization of cell-based GPCR assays, including calcium flux, cAMP, IP1/IP accumulation, beta-arrestin recruitment, receptor internalization, membrane potential, and related readouts.
Senior Scientist - Immunology Biology Arcus Biosciences, Inc.Senior Scientist - Immunology BiologyHayward, CA$160,000–$175,000 / yearPHYSICAL REQUIREMENTS: • Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds. The successful candidate will lead elements of drug discovery programs by providing scientific insight, generating robust experimental data packages, and developing mechanistic models of disease to advance Arcus drug candidates.
Senior Scientist - Immunology Biology Arcus Biosciences IncSenior Scientist - Immunology BiologyHayward, CA$160,000–$175,000 / yearPHYSICAL REQUIREMENTS: Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds. The successful candidate will lead elements of drug discovery programs by providing scientific insight, generating robust experimental data packages, and developing mechanistic models of disease to advance Arcus drug candidates.
Forward Deployed Research Scientist (Biology) GoodfireForward Deployed Research Scientist (Biology)San Francisco, California$220,000–$315,000 / yearProject delivery and implementation – own research delivery on high-stakes projects with customers and do whatever it takes to make delivery successful, including: problem and hypothesis definition, data sourcing, tool building, iteration, and implementation. Treating models as black boxes is an unnecessary handicap—we have access to the structures inside them, and understanding those structures lets us steer what models learn, make them safer and more useful, and extract the vast knowledge they contain.
Senior Scientist, Computational Biology Xaira TherapeuticsSenior Scientist, Computational BiologySouth San Francisco, CA$136,000–$170,000 / yearYou will work closely with wet-lab scientists, AI/ML scientists, automation engineers, and disease biology teams to develop scalable perturbation workflows, implement new technologies, and drive high-quality data generation and experimental innovation across multiple therapeutic areas. Deep expertise in single-cell RNA sequencing analysis with substantial hands-on experience in Perturb-seq or CRISPR-based perturbation screen data, including thorough familiarity with the full processing stack from raw reads to interpretable outputs.
Data Scientist, RNA Biology South San Francisco, Ca ESRhealthcare and EXEC STAFF RECRUITERSData Scientist, RNA Biology South San Francisco, CaSan Francisco, CaliforniaYou will lead the curation of RNA-focused datasets for ML training and validation, discover statistical patterns in our large-scale datasets evaluating RNA structure and RNA-small molecule interactions, and devise and implement new strategies to test the accuracy of our ML models. As a full-time Data Scientist on the Machine Learning team, you will work closely with scientists and engineers to apply and advance our technology platform for RNA structure prediction, target identification, and early-stage drug discovery.
Director, Virtual Biology Initiative BiohubDirector, Virtual Biology InitiativeRedwood City, CaliforniaAs the director of the Virtual Biology Initiative, you will play a central role in building that ecosystem -- bringing together the organizations, partnerships, and long-term collaborations needed to accelerate a new era of AI-enabled biology. Working closely with scientific, technical, legal, and operational leaders, this leader will coordinate across disciplines to ensure partnerships advance VBI's priorities and contribute to a cohesive, scalable ecosystem.
Research Associate II, Structural & Cellular Biology (Proteomics & CryoET) BiohubResearch Associate II, Structural & Cellular Biology (Proteomics & CryoET)Redwood City, CaliforniaYou will maintain and engineer cell lines, design and optimize sample-preparation workflows for both mass spectrometry and cryoET, and help implement proximity labeling, crosslinking, correlative light and electron microscopy (CLEM), and FIB-SEM lamella preparation to map protein interaction networks and cellular architecture. This role sits at the interface of two closely connected efforts within our Dynamic Structural Biology group, which maps the molecular architecture of living cells — charting how protein complexes assemble, where they localize, and how their organization shifts across cell states and in response to perturbation.
Evolutionary Cell Biology Fellow Arcadia Science LLCEvolutionary Cell Biology FellowEmeryville, CA$8,000–$12,000 / yearThis is an ideal opportunity for scientists in the final stages of their PhD or postdoc training who want to experience industry research in an open science environment working with diverse organisms, or for researchers excited to apply cell biology techniques across the tree of life. Because we use evolution to select the best organism to study each biological question, fellows will work with diverse, often non-traditional organisms and cell types.
Developmental & Stem Cell Biology BecomingDevelopmental & Stem Cell BiologySan Francisco, CaliforniaYou will build and operate long-horizon developmental systems from stem and primary cells, integrate them with engineered environments, and generate data that directly informs platform decisions. We are building systems that don’t — combining engineered metabolic environments, longitudinal measurement, and predictive models to turn development into something that can be understood, tested, and controlled.
NewBiology Specialist TuringBiology SpecialistSan Francisco, CaliforniaRemote$100–$200Turing supports customers in two ways: first, by accelerating frontier research with high-quality data, advanced training pipelines, plus top AI researchers who specialize in coding, reasoning, STEM, multilinguality, multimodality, and agents; and second, by applying that expertise to help enterprises transform AI from proof of concept into proprietary intelligence with systems that perform reliably, deliver measurable impact, and drive lasting results on the P&L. About Turing: Based in San Francisco, California, Turing is the world’s leading research accelerator for frontier AI labs and a trusted partner for global enterprises deploying advanced AI systems.