Research Scientist LancesoftResearch ScientistSan Diego, CA$33The role is a highly technical and/or specialized professional position responsible for supporting several disease areas across Client Biomedical Research (La Jolla, CA USA) providing high quality & consistent in vivo technical research support within our multi-building, multi-discipline research program. Our Global Genetically Engineered Models (GEMs) Team within Comparative Medicine (CM) supports the expansion of animal science, preclinical care, and research model development furthering research across the world.
Senior Scientist, Bioinformatics Kenai TherapeuticsSenior Scientist, BioinformaticsSan Diego, CA$140,000–$155,000This role requires exceptional technical skills, a proven ability to communicate complex findings across scientific disciplines, and a desire to thrive in a small, fast-moving organization where flexibility and initiative are essential. Kenai Therapeutics is seeking a skilled and versatile computational biologist to join our highly collaborative, multidisciplinary, and dynamic team advancing next-generation allogeneic cell therapies for neurological diseases.
Principal Scientist, Medicinal Chemistry Iambic TherapeuticsPrincipal Scientist, Medicinal ChemistrySan Diego, CaliforniaThe ideal candidate will be passionate about solving medicinal chemistry challenges, as well as proactively interfacing with diverse teams working on automated experimentation, AI-driven molecular generation, property predictions, and bioassay data generation. Execute on high quality ideas by employing a broad range of modern organic chemistry transformations, synthetic methods, creative use of parallel experimentations and implementing innovative techniques.
Senior Scientist Allen SpoldenSenior ScientistCarlsbad, CaliforniaComputer literacy required; knowledge of Microsoft Office (including extensive Excel skills) and experience with large enterprise resource planning (ERP) and electronic data management systems required. Excellent technical writing and documentation, communication, interpersonal, analytical, and presentation skills are essential.
Research Scientist I/II, Immunology Iambic TherapeuticsResearch Scientist I/II, ImmunologySan Diego, CaliforniaDesign, develop, optimize, troubleshoot, and execute assays using disease-relevant immune cells and tissues, including primary human and/or pre-clinical immune cells, whole blood, cell lines, and tissue-derived systems, to measure potency, selectivity, target engagement, mechanism of action, and functional immune responses. Ability to develop, troubleshoot, and document robust cell-based assay cascades using appropriate controls, counterscreens, and orthogonal readouts to confirm on-target activity and generate reproducible compound-profiling data; experience transferring assays to CROs or automated/HTS platforms is preferred.
Senior Scientist, Bioinformatics Insmed Gene TherapySenior Scientist, BioinformaticsSan Diego, CaliforniaRemoteYou’ll also: Design, develop, and maintain bioinformatics pipelines for the analysis of next-generation sequencing (NGS) data including whole-genome sequencing (WGS), whole-exome sequencing (WES), transcriptomics (bulk, single cell and spatial) and epigenomics. You will play a critical role in supporting Insmed Gene Therapy’s drug discovery and development pipeline by applying computational and statistical approaches to analyze complex biological datasets.
FSP - Scientist - Transient Expression Thermo Fisher ScientificFSP - Scientist - Transient ExpressionSan Diego, CaliforniaWith clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Through this collaborative approach, our professionals bring their commitment to excellence, industry knowledge, and operational strength directly into customer environments, helping to enhance capabilities and advance the delivery of life-changing therapies.
NewScientist I - LC/MS (Bioanalytical) BioAgilytixScientist I - LC/MS (Bioanalytical)San Diego, CALead the development, validation, and sample analysis of large molecules such as ADCs, monoclonal antibodies and other proteins, peptides, oligonucleotides, biomarkers, and small molecules using various techniques including chromatographic (LC-MS/MS) in support of preclinical and clinical PK/PD studies. Experience developing chromatographic assays using LC-MS/MS, HPLC, UPLC, and/or UPLC-HRMS, including protein binding, CYP inhibition, CYP induction, or CYP phenotyping assays.
NewScientist I - Lc/Ms (Bioanalytical) BioAgilytixScientist I - Lc/Ms (Bioanalytical)San Diego, CA$88,000–$99,000 / yearLead the development, validation, and sample analysis of large molecules such as ADCs, monoclonal antibodies and other proteins, peptides, oligonucleotides, biomarkers, and small molecules using various techniques including chromatographic (LC-MS/MS) in support of preclinical and clinical PK/PD studies. Experience developing chromatographic assays using LC-MS/MS, HPLC, UPLC, and/or UPLC-HRMS, including protein binding, CYP inhibition, CYP induction, or CYP phenotyping assays.
NewBioinformatics Data Scientist (Part-Time/Temporary) Artiva BiotherapeuticsBioinformatics Data Scientist (Part-Time/Temporary)San Diego, CA$55–$65 / hourPerform multi-omics and biomarker analysis including quality control, normalization, batch correction, differential expression analysis, clustering, dimensionality reduction (PCA, UMAP, t-SNE), cell type annotation, comparative analysis, and pathway analysis. Required Qualifications: Bachelor's or master's degree (preferred) in Computer Science, Data Science, Bioinformatics, Computational Biology, or related field, and demonstrated experience (typically 2+ years) in bioinformatics pipeline development and biological data science.
Senior Staff Bioinformatics Scientist Illumina, Inc.Senior Staff Bioinformatics ScientistSan Diego, CARemoteFull timeDesign, evaluate, and implement scalable bioinformatics workflows for bulk RNA-seq, single-cell sequencing, CRISPR/Perturb-seq analysis, ATAC-seq, CROP-seq, and emerging multiomic assays. The successful candidate will combine biological insight with strong algorithmic, statistical, and software engineering skills, and will provide technical leadership and product development experience across multiple product cycles.
Senior Staff Bioinformatics Scientist -- Dna/Rna Secondary Analysis Algorithms IlluminaSenior Staff Bioinformatics Scientist -- Dna/Rna Secondary Analysis AlgorithmsSan Diego, CARemote$170,600–$255,800 / yearDesign, evaluate, and implement scalable bioinformatics algorithms and methods for bulk RNA-seq, single-cell sequencing, CRISPR/Perturb-seq analysis, ATAC-seq, CROP-seq, and emerging multiomic assays. The successful candidate will combine biological insight with strong algorithmic, statistical, and software engineering skills, and will provide technical leadership and product development experience across multiple product cycles.
Toxicology Research Scientist Vertex PharmaceuticalsToxicology Research ScientistSan Diego, California$101,600–$152,400 / yearThe successful candidate will have a proven track record of working with complex in vitro models, including primary cells and immune cells in 3D formats or co-culture systems, and will bring expertise in developing and applying innovative approaches to assess molecular toxicities. This lab-based role offers an exciting opportunity to lead the development of advanced 3D organoid models, organ-on-a-chip technologies, and fit-for-purpose assays to investigate toxicological mechanisms and support our therapeutic discovery and development efforts.
Scientist II, Bioinformatics QC Aspen NeuroscienceScientist II, Bioinformatics QCSan Diego, California$129,600–$158,400Aspen Neuroscience, Inc., located in scenic Torrey Pines, is noted for its collaborative and learning focused culture where each person is valued for contributing their strengths and energy to building a world-class line of products for patients in need. In this role you will be taking ownership of a critical priority, bringing together multiple teams and ensuring the quality of our product, contributing directly to delivering novel cell therapy to patients.
Scientist II WuXi AppTecScientist IISan Diego, California$82,731–$107,132 / yearThe position will independently design, execute, trouble shoot and deliver the projects with LC-MS (liquid chromatography – mass spectrometry), prioritizing large molecules such as biologics, peptides, ADCs (antibody drug conjugates), LNPs (lipid nanoparticles), and oligos, and including small molecule modalities when necessary. Technical expertise: Solid understanding of qualitative and quantitative LC-MS workflows for ADCs, LNPs, peptides/proteins, biologics, small molecules, including associated sample preparation techniques.
Scientist II - Bioassay RevvityScientist II - BioassaySan Diego, California$100,000–$120,000 / yearThis role is responsible for developing and optimizing cell-based bioassays and functional binding assays to evaluate the activity and performance of recombinant proteins and neutralizing antibodies, supporting research, development, and product quality initiatives. The base pay actually offered to the successful candidate will take into account internal equity, work location, and additional factors, including job-related skills, experience, and relevant education or training.
Scientist I - LC/MS (Bioanalytical) BioAgilytix Labs LLCScientist I - LC/MS (Bioanalytical)San Diego, CA$88,000–$99,000 / yearLead the development, validation, and sample analysis of large molecules such as ADCs, monoclonal antibodies and other proteins, peptides, oligonucleotides, biomarkers, and small molecules using various techniques including chromatographic (LC-MS/MS) in support of preclinical and clinical PK/PD studies. Experience developing chromatographic assays using LC-MS/MS, HPLC, UPLC, and/or UPLC-HRMS, including protein binding, CYP inhibition, CYP induction, or CYP phenotyping assays.
Scientist I, Analytical Development ImmunityBioScientist I, Analytical DevelopmentSan Diego, CAThe role will assist in developing, optimizing and validating bioassays to support cell therapy projects and will be responsible for supporting the efficient operation of the laboratory and performing scientific studies to support cell therapy projects. Designated an FDA Breakthrough Therapy, ANKTIVA is the first FDA-approved immunotherapy for non-muscle invasive bladder cancer CIS that activates NK cells, T cells, and memory T cells for a long-duration response.
NewIn Vitro Pharmacology Scientist TCWGlobalIn Vitro Pharmacology ScientistSan Diego, CaliforniaIn this role, you will contribute to multiple multidisciplinary drug discovery projects, supporting lead optimization campaigns and new target screening efforts through the development, optimization, and execution of robust biochemical and cell-based assays. The ideal candidate has hands-on experience with a broad range of in vitro biological assays and tissue culture, strong experimental design and data analysis skills, and the ability to independently plan and execute experiments.
NewSr. Bioinformatics Scientist Singular GenomicsSr. Bioinformatics ScientistSan Diego, CA$131,600–$154,800 / yearThis includes selecting biologically informative genes for cell type identification, defining pathway-focused content that enables cell-state interpretation, and developing computational tools to automate and improve panel design. As the platform and services continue to evolve, you will contribute to the development of spatial bioinformatics workflows, analysis pipelines, and computational methods that enable customers to generate meaningful biological insight from spatial multiomics data.