Senior Medical Director, Clinical Development Beeline MedicinesSenior Medical Director, Clinical DevelopmentBoston, Massachusetts$293,000–$379,500 / yearSupport pharmacovigilance activities during trial conduct — Drive cross-functional clinical program teams as the senior medical lead — providing strategic scientific direction to Clinical Operations, Regulatory Affairs, Translational Medicine, Biostatistics, and Medical Affairs — and ensure integrated, high-quality program execution with clear accountability and pace. The Senior Medical Director serves as the primary physician lead for assigned assets, owning the clinical strategy and development plan across multiple phases, while also playing an increasingly prominent role in shaping departmental capabilities, mentoring junior physicians, and contributing to portfolio-level decision-making.
Clinical Research Coordinator - Surgery FIRST Program Lahey Hospital and Medical CenterClinical Research Coordinator - Surgery FIRST ProgramBoston, MA$21.64–$26.50 / hourResponsible for screening research subjects for participation in clinical research projects, enrolling research subjects onto these studies, monitoring protocol implementation, completing required forms, reporting results, maintaining regulatory paperwork, and entering data into databases. Customer Service: Ability to provide a high level of customer service to patients, visitors, staff and external customers in a professional, service-oriented, respectful manner using skills in active listening and problem solving.
Sr. Manager Quality Assurance Alnylam Pharmaceuticals IncSr. Manager Quality AssuranceMARemote$226,600–$280,700 / yearMust also have demonstrated experience in the following: BI content promotion and project support, administrating, supporting, troubleshooting, installing, configuring, and programming SAS; Working with BI tools and Data Integration; SAS applications installation and project migration; Windows and UNIX Servers in supporting SAS users; Real-world healthcare database research; Synthesizing multiple healthcare data sets to generate new insights in evidence to support commercial objectives; Statistical modelling of observational healthcare data sets; and SAS programming. In lieu of a Master's degree in Pharmacy, Economics, Biostatistics, epidemiology, or related field of study and six (6) years of work experience in the job offered or related occupation in which the required experience was gained, employer will also accept a PhD in Pharmacy, Economics, Biostatistics, epidemiology, or related field of study and four (4) years of work experience in the job offered or related occupation in which the required experience was gained.
Biostatistician Costello MedicalBiostatisticianBoston, MA$75,000–$80,000 / yearAlongside our award-winning company culture, where every team member is celebrated, respected, and has their voice heard, our comprehensive benefits package includes: A starting salary of $75,000 to $80,000 per annum, depending on your qualifications and previous experience, as well as a discretionary profit share bonus paid twice per year. Delivering project work requires close collaboration with clients and, following a successful induction period, you will increasingly participate in client calls and face-to-face meetings with external stakeholders.
Principal Biostatistician Entrada TherapeuticsPrincipal BiostatisticianBoston, MassachusettsRemote$203,000–$247,000 / yearWe are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families. We expect multiple clinical data readouts as we advance several DMD programs across the U.K., EU, and U.S. By year-end 2026, we anticipate four clinical-stage programs in our DMD franchise (ENTR-601-44, ENTR-601-45, ENTR-601-50, and ENTR-601-51).
Senior Director, Biometrics Prime Medicine, Inc.Senior Director, BiometricsCambridge, MA$263,000–$292,000 / yearPrime Medicine is seeking an experienced Senior Director, Biometrics to serve as the senior biostatistics leader for the organization while providing strategic and operational leadership for the broader Biometrics function, including Clinical Data Management, in support of our gene editing clinical programs. Although responsible for the broader Biometrics function, this position is first and foremost a senior biostatistics leadership role requiring deep expertise in clinical trial design, statistical methodology, regulatory interactions, and quantitative decision-making across clinical development.
Post-doctoral Research Fellow, Center for Genomic Medicine Mass General BrighamPost-doctoral Research Fellow, Center for Genomic MedicineBoston, MassachusettsThe successful candidate will have opportunities to work with clinical, genetic, and multi-omic data from large-scale EHR-based biobanks (e.g., MGB Biobank, All of Us, etc.), pregnancy / birth cohorts (e.g., Boston Birth Cohort, TOPMed BCC-PREG and nuMoM2b-HHS studies, etc.), and longitudinal cohort studies (e.g., Nurses Health Studies, Women’s Health Initiative, ROSMAP, TOPMed cohorts, etc.). Dr. Jie (Jack) Hu and Dr. Richa Saxena in the Center for Genomic Medicine (CGM) at the Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), are seeking a highly motivated post-doctoral fellow candidate working in areas of life-course epidemiology, integrated omics, women’s and children’s health, and chronic disease prevention.
Senior Director, Biometrics Prime Medicine IncSenior Director, BiometricsCambridge, MA$263,000–$321,000 / yearPrime Medicine is seeking an experienced Senior Director, Biometrics to serve as the senior biostatistics leader for the organization while providing strategic and operational leadership for the broader Biometrics function, including Clinical Data Management, in support of our gene editing clinical programs. Although responsible for the broader Biometrics function, this position is first and foremost a senior biostatistics leadership role requiring deep expertise in clinical trial design, statistical methodology, regulatory interactions, and quantitative decision-making across clinical development.
Senior Director, Biometrics Prime MedicineSenior Director, BiometricsCambridge, MA$263,000–$321,000 / yearPrime Medicine is seeking an experienced Senior Director, Biometrics to serve as the senior biostatistics leader for the organization while providing strategic and operational leadership for the broader Biometrics function, including Clinical Data Management, in support of our gene editing clinical programs. Although responsible for the broader Biometrics function, this position is first and foremost a senior biostatistics leadership role requiring deep expertise in clinical trial design, statistical methodology, regulatory interactions, and quantitative decision-making across clinical development.
Real World Evidence Associate Director Vertex Pharmaceuticals IncReal World Evidence Associate DirectorBoston, MA$174,400–$261,600 / yearKey Duties and Responsibilities: Independently lead focused/targeted research of epidemiology of specific disease areas, including NH of disease for business development and early development indicationsLead data sourcing strategy for early development and early clinical indications to support NH of disease needed for regulators, payers, and cliniciansLead and execute evaluation of available registries and other data sources related to NH and evidence to support clinical endpoints and inclusion/exclusion criteriaDetermine potential use of RWE historical control within clinical development program and feasibility of obtaining data required for historical controlLead execution of approved research tactics within assigned indicationsDevelop draft protocol concept and related materials for review and approval by internal scientific review boardsWorking closely with stakeholders, align RWE research study tactics with functional and disease program goalsContribute to development of performance metrics and dashboards for RWE projectsRepresent RWE on relevant GMDA Sub-Teams, Program Teams, or Disease Strategy Teams where studies related to RWE are discussedRepresent RWE on cross-functional collaborations and working groups for pipeline product(s)Utilize strong oral communications skills and understanding of Vertex strategies to promote and translate RWD/RWE methods and activities across the companySupport and facilitate external research collaborations with key academic partners, consortia, and data vendorsSupport the development of cross-functional evidence generation planning Provide leadership and mentorship within RWEContribute to company publications strategy via development of conference abstracts, presentations, peer-reviewed manuscripts based on the findings of RWE studies. Knowledge and Skills: Applied knowledge of relevant RWE regulatory agency guidance and position papers and the opportunities to use RWE to inform regulatory decision makingDemonstrated ability to design and execute observational researchStrong and clear interpersonal communication, presentation, and study management skillsAbility to take detailed observational study results and communicate them in a clear, non- technical manner to internal cross-functional teams, using language that resonates with the teams, while maintaining the integrity of key findingsAbility to work collaboratively in a constantly changing, diverse, and matrix environment.
Post-doctoral Research Fellow, Center for Genomic Medicine Brigham and Women's HospitalPost-doctoral Research Fellow, Center for Genomic MedicineBoston, MA$70,000–$71,500 / yearThe successful candidate will have opportunities to work with clinical, genetic, and multi-omic data from large-scale EHR-based biobanks (e.g., MGB Biobank, All of Us, etc.), pregnancy / birth cohorts (e.g., Boston Birth Cohort, TOPMed BCC-PREG and nuMoM2b-HHS studies, etc.), and longitudinal cohort studies (e.g., Nurses Health Studies, Women's Health Initiative, ROSMAP, TOPMed cohorts, etc.). Dr. Jie (Jack) Hu and Dr. Richa Saxena in the Center for Genomic Medicine (CGM) at the Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), are seeking a highly motivated post-doctoral fellow candidate working in areas of life-course epidemiology, integrated omics, women's and children's health, and chronic disease prevention.
Post-Doctoral Research Fellow, Center For Genomic Medicine Brigham and Women's HospitalPost-Doctoral Research Fellow, Center For Genomic MedicineBoston, MA$71,750–$81,179 / yearThe successful candidate will have opportunities to work with clinical, genetic, and multi-omic data from large-scale EHR-based biobanks (e.g., MGB Biobank, All of Us, etc.), pregnancy / birth cohorts (e.g., Boston Birth Cohort, TOPMed BCC-PREG and nuMoM2b-HHS studies, etc.), and longitudinal cohort studies (e.g., Nurses Health Studies, Women's Health Initiative, ROSMAP, TOPMed cohorts, etc.). Dr. Jie (Jack) Hu and Dr. Richa Saxena in the Center for Genomic Medicine (CGM) at the Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), are seeking a highly motivated post-doctoral fellow candidate working in areas of life-course epidemiology, integrated omics, women's and children's health, and chronic disease prevention.