NewAssoc Dir/Director Clinical Scientist Kura OncologyAssoc Dir/Director Clinical ScientistBoston, MA$226,000–$264,000 / yearKura developed and is commercializing KOMZIFTI® (ziftomenib), the FDA-approved once-daily, oral menin inhibitor for the treatment of adults with relapsed or refractory NPM1-mutated acute myeloid leukemia, and continues to pioneer advancements in menin inhibition and farnesyl transferase inhibition. Broad understanding of functional areas of drug development, including preclinical, regulatory, pharmacovigilance, drug supply, data sciences (data management, biostatistics, programming), and clinical operations (including site selection, study start-up, study conduct, and finalization).
Lead statistical Programmer Karwell TechnologiesLead statistical ProgrammerBoston, MAThe position involves hands-on technical leadership and requires comprehensive and detailed knowledge of statistical programming languages and software, filing support, clinical trial databases, and the drug development process. The role oversees external CRO partners to ensure high-quality, timely, and compliant delivery of analysis datasets, tables, listings, and figures that support clinical development and regulatory submissions.
Lead statistical Programmer Katalyst Healthcares & Life SciencesLead statistical ProgrammerBoston, MAThe position involves hands-on technical leadership and requires comprehensive and detailed knowledge of statistical programming languages and software, filing support, clinical trial databases, and the drug development process. The role oversees external CRO partners to ensure high-quality, timely, and compliant delivery of analysis datasets, tables, listings, and figures that support clinical development and regulatory submissions.
Associate Director, Data Science Rhythm PharmaceuticalsAssociate Director, Data ScienceBoston, MARemoteFull timeA core focus of this position will be the development and implementation of algorithmic phenotyping approaches using electronic medical records (EMR) and real-world datasets, enabling robust patient stratification, cohort definition, and integration with genomics and biomarker data. We are seeking a highly motivated Associate Director of Data Science within Rhythm's Research group and the Data Sciences Team in support of our clinical, regulatory, and scientific objectives in the rare neuroendocrine/obesity/metabolic disease.
Associate Director, Functional Genomics, Data Science Merck & Co IncAssociate Director, Functional Genomics, Data ScienceCambridge, MA$176,200–$277,300 / yearRequired Skills: Amazon Web Services (AWS), Bioinformatics, Biostatistics, Computer Science, CRISPR-Cas System, Data Engineering, Data Modeling, Data Science, Data Visualization, Genome, Genomics, Hypothesis Testing, Linux Environments, Machine Learning (ML), Model Fine-Tuning, Omics, Single-Cell Genomics, Software Development, Stakeholder Relationship Management, Statistical Design of Experiments (DOE), Statistical Programming. Integrate functional genomics and imaging derived results with high throughput transcriptomics and proteomics datasets to build multi evidence target prioritization packages for multiple stages of drug discovery.
Manager/Senior Manager, Clinical Data Management Beam Therapeutics IncManager/Senior Manager, Clinical Data ManagementCambridge, MA$130,000–$190,000 / yearBeam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. Reporting to the Senior Director of Data Management, this role is responsible for driving study-level data management activities from study start-up through database lock while ensuring high-quality, inspection-ready clinical data.
Postdoctoral Research Position in Causal Inference Harvard UniversityPostdoctoral Research Position in Causal InferenceCambridge, MACore data resources include nationwide claims, linked with rich contextual information such as census data, weather records, and high-resolution air pollution and related environmental exposures data. Motivated by relevant public health and policy questions, the goal is to develop methodologies for the identification, estimation, transportability, and generalization of the causal effects in complex real-world settings.
NewExecutive Director, Clinical Science, Oncology, Hematology, Oncology Assets and Early Development Merck & Co IncExecutive Director, Clinical Science, Oncology, Hematology, Oncology Assets and Early DevelopmentBoston, MA$255,800–$402,700 / yearRequired Skills: Advanced Analytics, Artificial Intelligence (AI), Clinical Development, Clinical Sciences, Cross-Functional Leadership, Executive Leadership, Global Clinical Studies, Innovation, Matrix Leadership, Oncology, Oncology Drug Development, Regulatory Submissions, Strategic Leadership, Talent Development. The Executive Director, Clinical Science is a senior leader within Oncology Clinical Development responsible for providing strategic, scientific, operational, and people leadership across a portfolio of oncology programs spanning multiple therapeutic areas (Hematology, Oncology Assets and Early Development) and stages of development.
NewExecutive Director, Clinical Science, Oncology, Genitourinary, Melanoma, and Women's Cancers Merck & Co IncExecutive Director, Clinical Science, Oncology, Genitourinary, Melanoma, and Women's CancersBoston, MA$255,800–$402,700 / yearRequired Skills: Advanced Analytics, Artificial Intelligence (AI), Clinical Development, Clinical Sciences, Cross-Functional Leadership, Executive Leadership, Global Clinical Studies, Innovation, Matrix Leadership, Oncology, Oncology Drug Development, Regulatory Submissions, Strategic Leadership, Talent Development. The Executive Director, Clinical Science is a senior leader within Oncology Clinical Development responsible for providing strategic, scientific, operational, and people leadership across a portfolio of oncology programs spanning multiple therapeutic areas (Genitourinary, Melanoma, and Women's Cancers) and stages of development.
NewExecutive Director, Clinical Science, Ophthalmology & Neuroscience Merck & Co IncExecutive Director, Clinical Science, Ophthalmology & NeuroscienceBoston, MA$255,800–$402,700 / yearRequired Skills: Advanced Analytics, Artificial Intelligence (AI), Clinical Development, Clinical Sciences, Cross-Functional Leadership, Drug Development, Executive Leadership, Global Clinical Studies, Innovation, Matrix Leadership, Neuroscience, Ophthalmology, Regulatory Submissions, Strategic Leadership, Talent Development. Partner withthe Ophthalmology and Neuroscience Therapeutic Area Heads and leaders across Clinical Operations, Regulatory Affairs, Biostatistics and Data Management, Drug Safety and Pharmacovigilance, Translational Medicine, and Medical Affairs to drive development strategy execution and delivery of key portfolio milestones.
NewExecutive Director, Clinical Science, Oncology, Thoracic, Lung, Head & Neck, and Gastrointestinal Merck & Co IncExecutive Director, Clinical Science, Oncology, Thoracic, Lung, Head & Neck, and GastrointestinalBoston, MA$255,800–$402,700 / yearRequired Skills: Advanced Analytics, Artificial Intelligence (AI), Clinical Development, Clinical Sciences, Cross-Functional Leadership, Executive Leadership, Global Clinical Studies, Innovation, Matrix Leadership, Oncology, Oncology Drug Development, Regulatory Submissions, Strategic Leadership, Talent Development. The Executive Director, Clinical Science is a senior leader within Oncology Clinical Development responsible for providing strategic, scientific, operational, and people leadership across a portfolio of oncology programs spanning multiple therapeutic areas (Thoracic, Lung, Head & Neck, and Gastrointestinal Cancers) and stages of development.
NewExecutive Director, Clinical Science, Infectious Disease & Vaccines Merck & Co IncExecutive Director, Clinical Science, Infectious Disease & VaccinesBoston, MA$255,800–$402,700 / yearRequired Skills: Advanced Analytics, Artificial Intelligence (AI), Clinical Development, Clinical Sciences, Cross-Functional Leadership, Drug Development, Executive Leadership, Global Clinical Studies, Infectious Disease, Innovation, Matrix Leadership, Regulatory Submissions, Strategic Leadership, Talent Development. The Executive Director, Clinical Science is a senior leader within Non-Oncology Clinical Development responsible for providing strategic, scientific, operational, and people leadership across a portfolio of infectious diseases and vaccines programs spanning multiple stages of development.
NewExecutive Director, Clinical Science, Immunology Merck & Co IncExecutive Director, Clinical Science, ImmunologyBoston, MA$255,800–$402,700 / yearRequired Skills: Advanced Analytics, Artificial Intelligence (AI), Clinical Development, Clinical Sciences, Cross-Functional Leadership, Drug Development, Executive Leadership, Global Clinical Studies, Immunology, Innovation, Matrix Leadership, Regulatory Submissions, Strategic Leadership, Talent Development. The role champions innovation and modern ways of working by advancing the adoption of digital capabilities, advanced analytics, artificial intelligence, and data-driven approaches that enhance decision-making, improve efficiency, and strengthen study oversight across the portfolio.
NewStudy Physician, Medical Director - Neuroimmunology, Immunology, BioPharmaceuticals R&D AstraZeneca PlcStudy Physician, Medical Director - Neuroimmunology, Immunology, BioPharmaceuticals R&DCambridge, MA$241,613–$362,420 / yearContribute medical content and final medical review to clinical sections of study- and program-level documents such as protocols, ICFs, IB, briefing books, BTD, PIPs, SAPs, and safety periodic reports, providing risk-benefit framing and clinical rationale. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles).
Clinical Data Manager, Oncology Sunrise Systems IncClinical Data Manager, OncologyMarlborough, MARemote$66.98–$73.68 / hourThis position reports to the Executive Director, Clinical Data Management, Oncology and is part of the Oncology Data Management function, which supports Sumitomo Pharma America''s clinical development programs by ensuring high-quality, compliant, and inspection-ready clinical trial data. The role is responsible for the end-to-end execution and oversight of clinical data management activities across assigned oncology studies and works closely with Clinical Operations, Biostatistics, Medical Monitoring, Safety, Clinical Systems, and external vendors.
NewAssociate Director, Clinical Scientist - Neuroimmunology AstraZeneca PlcAssociate Director, Clinical Scientist - NeuroimmunologyCambridge, MA$142,000–$213,000 / yearYou will report to the Global Clinical Head, Neuroimmunology, or their designee, and work closely with the Study Physician, fellow clinical scientists, and the Global Clinical Program Lead (GCPL), who leads the program's clinical development strategy. Contribute to query generation, coding reconciliation (AE/SAE, medical/surgical history, concomitant medications), and edit-check refinement in collaboration with Data Management and Biostatistics, and support database-lock readiness activities and cross-checks.
Executive Director/Vice President - Therapy Area Head- Cardiorenal MannKind CorpExecutive Director/Vice President - Therapy Area Head- CardiorenalBedford, MAWith a focus on cardiometabolic and orphan lung diseases, we develop and commercialize treatments that address serious unmet medical needs, including diabetes, pulmonary hypertension, pulmonary fibrosis, nontuberculous mycobacterial (NTM) lung disease, and fluid overload associated with heart failure and chronic kidney disease. This executive role contributes to the design, execution, and strategic progression of development-stage and postmarketing clinical programs as well as leads the medical strategy for scientific exchange on the marketed products- ensuring scientific accuracy, strong clinical evidence, and alignment with the company's corporate vision.
Executive Director, Clinical Data Management Dianthus Therapeutics IncExecutive Director, Clinical Data ManagementCambridge, MAOur second clinical candidate, DNTH212 is a first and potentially best in class, bifunctional inhibitor that targets clinically validated and complementary disease modifying mechanisms, Type 1 IFN suppression and B cell modulation - enabling potential for improved clinical outcomes and patient friendly convenient, self-administered subcutaneous injections. As the functional leader for Clinical Data Management, the Executive Director will be responsible for building and scaling the department, developing talent, establishing SOPs and governance frameworks, and ensuring the delivery of high-quality, regulatory-compliant clinical data to support critical business decisions, regulatory submissions, and future commercialization efforts.
Director/Senior Director, Pharmacovigilance and Drug Safety (Safety Scientist) Xenon PharmaceuticalsDirector/Senior Director, Pharmacovigilance and Drug Safety (Safety Scientist)Needham, MassachusettsThe successful candidate will author safety documents, reviews safety sections of other documents, for Xenon products throughout the product lifecycle from First-in-Human (FIH) to post-marketing, performs QC, and, when necessary, assists in responding to information requests from Health Authorities for Xenon products, participate in cross-functional Safety Risk Management Team (SRMT) meetings and collaborate with colleagues in Clinical Development, Trial Operations, Clinical Pharmacology, Biostatistics & Programming, Regulatory, Medical Affairs, non-clinical safety lead, QA and Legal departments. * Support and review safety-related documents for Xenon products throughout product lifecycle from FIH to post-marketing such as Safety Assessment Reports, product labeling, risk management/risk mitigation-related documents, and responses to ad-hoc information requests by Health Authorities and internal stakeholders.
NewPrincipal Data Scientist Gradient AIPrincipal Data ScientistBoston, MARemoteDeep experience being accountable for model impact long term – from MLOps pipelines to monitor for drift, to KPI and impact monitoring, driving incremental and long-term improvements, triaging issues, addressing tech debt responsibly, etc. Our platform harnesses a vast industry data lake – tens of millions of policies and claims enriched with economic, health, geographic, and demographic signals – integrating cleanly with existing workflows to make complex risk clear, usable, and actionable.