Clinical Dynamix, Inc.NewAssociate Director, Biostatistics Clinical Dynamix, Inc.Associate Director, BiostatisticsBurlington, MAspecific responsibilities while upholding our core working behaviors of Trust and Respect, Communication and Feedback, Accountability and Reliability, Objectivity, and Team Balance and. •Provide high-quality statistical support across clinical programs, ensuring scientific.
Beam TherapeuticsAssociate Director/Director, Biostatistics Beam TherapeuticsAssociate Director/Director, BiostatisticsCambridge, MA$185,000–$260,000 / yearBeam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. The ideal candidate will work closely with the Head of Biometrics and play a key role in the statistical strategy for clinical development programs and provide oversight to CROs to ensure timely execution of the clinical trials.
Kymera TherapeuticsDirector of Biostatistics Kymera TherapeuticsDirector of BiostatisticsWatertown, MA$195,000–$275,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. As the Lead Statistician, you will spearhead the statistical efforts of a clinical program, playing a key role in the clinical development plan, regulatory submissions, and overall data strategy.
Tempus AI IncDirector, Biostatistics Tempus AI IncDirector, BiostatisticsBoston, MA$180,000–$240,000 / yearSalary Range: CHI: $180,000-$240,000 USD NYC/SF: $190,000-$260,000 The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). We are seeking a highly motivated and capable Director of Biostatistics to lead a team of biostatisticians involved in multiple aspects of clinical research at Tempus.
Kymera Therapeutics IncDirector, Biostatistics Kymera Therapeutics IncDirector, BiostatisticsWatertown, MA$195,000–$275,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. How you'll make an impact: As the Lead Statistician, you will spearhead the statistical efforts of a clinical program, playing a key role in the clinical development plan, regulatory submissions, and overall data strategy.
Monte Rosa Therapeutics, IncDirector, Biostatistics Monte Rosa Therapeutics, IncDirector, BiostatisticsBoston, MassachusettsThe Director will work closely with Clinical Development and external partners to drive trial design, analysis strategies, and regulatory‑ready outputs while remaining directly involved in study‑level statistical activities. Overview: The Director of Biostatistics is a hands‑on statistical leader responsible for the design, analysis, and interpretation of Phase 1–Phase 3 clinical trials with a primary focus on inflammation and oncology indications.
PhaseVBiostatistics Researcher PhaseVBiostatistics ResearcherCambridge, MAResearch: Support the development of research papers for statistical, machine learning, and medical journals on modern methodological approaches relevant to the company's interests and computing platform development, as well as applied papers growing out of consulting projects or conference interactions. PhaseV is a Boston-based technology company that redefines clinical development at scale with its enterprise-ready, multi-modal AI/ML platform — accelerating decisions, de-risking trials, and driving more efficient portfolio strategies.
CEDENTSenior Director, Biostatistics CEDENTSenior Director, BiostatisticsBoston, MAEnsure the accuracy, integrity, and consistency of statistical analyses across clinical development programs, from Phase I through regulatory submissions and post-approval activities. In this leadership role, you will oversee the development, execution, and interpretation of statistical analyses, maintaining data quality, analysis integrity, and compliance with regulatory requirements.
Relay TherapeuticsAssociate Director / Director, Biostatistics Relay TherapeuticsAssociate Director / Director, BiostatisticsCambridge, MA$154,000–$250,000 / yearBuilt on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. You will be an integrated member of the Relay Tx clinical development team, responsible for the in-house biostatistics expertise for the execution of clinical studies that will translate Relay's innovative science into impactful medicines for patients.
Penfield Search PartnersDirector Biostatistics Penfield Search PartnersDirector BiostatisticsBoston, MAAs a global biotherapeutics leader, they develop innovative therapies across immunology, hematology, cardiovascular, metabolic, respiratory, and transplant medicine—leveraging cutting-edge platforms including plasma fractionation, recombinant protein technology, and cell & gene therapy. Our client is a global biopharma company looking for two Directors, Biostatistics to lead statistical strategy across clinical programs and drive excellence from study design through regulatory submission.
Vor BioPharma IncDirector, Biostatistics Vor BioPharma IncDirector, BiostatisticsBoston, MA$230,000–$250,000 / yearReporting to the Head of Biometrics, this individual will serve as Vors global expert in biostatistical science, with accountability for all aspects of clinical trial design, statistical methodology, regulatory submission deliverables, and cross-functional scientific partnership. Regulatory Affairs & Submission Leadership • Author and review statistical sections of regulatory documents including INDs, investigator brochures, briefing books, CSRs, and eCTD/CTD module submissions to FDA, EMA, and other health authorities.
Avalyn PharmaDirector, Biostatistics Avalyn PharmaDirector, BiostatisticsCambridge, MA$228,000–$245,000 / yearThis role combines scientific depth, regulatory rigor, and operational execution to ensure the design, analysis, and interpretation of clinical trials support efficient development and high-quality regulatory submissions. The Director serves as a key partner to Clinical Development, Clinical Operations Data Management, Regulatory Affairs, Medical Affairs and while building scalable biostatistics capabilities appropriate for a growing organization.
Alnylam Pharmaceuticals IncExecutive Director Biostatistics Alnylam Pharmaceuticals IncExecutive Director BiostatisticsCambridge, MA$301,800–$408,200 / yearLead the development and implementation of statistical strategies across programs including clinical trial designs, endpoint strategies, and regulatory strategies, partnering with Clinical Development and cross-functional leaders to shape development plans. The Executive Director leads a team of statisticians and works closely with cross‑functional leaders to ensure rigorous and innovative quantitative approaches to drug development.
Vertex Pharmaceuticals IncBiostatistics Associate Director Vertex Pharmaceuticals IncBiostatistics Associate DirectorBoston, MA$236,000–$354,000 / yearGeneral Summary: The Associate Director, Biostatistics will perform sophisticated scientific statistical analyses in support of the company's Global Medicines Development and Affairs area with minimal guidance and mentoring on new and complex issues. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Vertex Pharmaceuticals IncBiostatistics Director (Hybrid) Vertex Pharmaceuticals IncBiostatistics Director (Hybrid)Boston, MAGeneral Summary: The Director, Biostatistics will independently perform highly scientific statistical functions in support of the company's Global Medicines Development and Affairs (GMDA) area on new and complex issues. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Les Laboratoires Servier SASAssociate Director, Biostatistics Les Laboratoires Servier SASAssociate Director, BiostatisticsBoston, MARemote$180,000–$215,000 / yearProvide statistical support on one or more assets or indications by directing the execution of statistical analyses, review of statistical outputs, and ensuring accurate results interpretation, collaborating closely with physicians, evidence generation stakeholders, or other cross-functional leads as appropriate on the interpretation of clinical results. Provide guidance to the clinical, regulatory, and/or evidence generation teams on conclusions and inferences from the data package, ensuring statistical perspective is integrated into regulatory and external meetings, and delivering data packages aligned with submission requirements or key decision-making.
Katalyst Healthcares & Life SciencesLead statistical Programmer Katalyst Healthcares & Life SciencesLead statistical ProgrammerBoston, MAThe position involves hands-on technical leadership and requires comprehensive and detailed knowledge of statistical programming languages and software, filing support, clinical trial databases, and the drug development process. The role oversees external CRO partners to ensure high-quality, timely, and compliant delivery of analysis datasets, tables, listings, and figures that support clinical development and regulatory submissions.
Beam TherapeuticsSr. Manager/AD, Statistical Programmer Beam TherapeuticsSr. Manager/AD, Statistical ProgrammerCambridge, MA$155,000–$225,000 / yearManage the activities of data summary, statistical analysis, patient profile, safety and efficacy tables, listings and figures using Base SAS, SAS Macros, SAS/STAT, SAS/Graph, SAS/SQL, SAS/ODS and R. Beam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA.
Karwell TechnologiesLead statistical Programmer Karwell TechnologiesLead statistical ProgrammerBoston, MAThe position involves hands-on technical leadership and requires comprehensive and detailed knowledge of statistical programming languages and software, filing support, clinical trial databases, and the drug development process. The role oversees external CRO partners to ensure high-quality, timely, and compliant delivery of analysis datasets, tables, listings, and figures that support clinical development and regulatory submissions.
Tufts UniversityBiostatistician - Friedman School of Nutrition Tufts UniversityBiostatistician - Friedman School of NutritionBoston, MassachusettsStrong quantitative training, experience applying statistical methods in health or clinical research settings, and an interest in advancing rigorous, equity-centered research related to food, nutrition, and health that has real-world impact and makes a difference in people’s lives. Document and maintain reproducible analysis workflows, including well-annotated statistical code, version-controlled scripts, clear data dictionaries, and organized file structures that support transparency and replication.
MMSSenior Biostatistician - Remote (US) MMSSenior Biostatistician - Remote (US)Boston, MARemoteFull timeLeads projects (all phases and even a program of studies) and smaller submissions, manages client meetings, CRMs, collaborates well with regulatory, PMs and sponsor. With a global footprint across four continents, MMS not only maintains an industry-leading customer satisfaction rating but also fosters a collaborative and inclusive work environment where employees can thrive.
LLX SolutionsBiostatistician LLX SolutionsBiostatisticianWaltham, Massachusetts$80,000–$85,000Additionally, this position will support Project Directors in the production and presentation of Data Monitoring Committee reports, analyzing data for regulatory submissions and publications, and communicating with clients and team members if desired. Position Overview:The Biostatistician may review protocols and case report forms, perform sample size calculations, write Statistical Analysis Plans, develop and produce interim and final reports.
MMSPrincipal Biostatistician - Remote MMSPrincipal Biostatistician - RemoteBoston, MARemoteFull timeProduce and present external company presentations providing industry visibility for the organization; Continually suggesting solutions to solve issues in tune with organizational direction. Lead complex projects, programs and submissions, manages client meetings, CRMs, collaborates well with regulatory, PMs and sponsors.
Alnylam Pharmaceuticals IncDirector Epidemiology Alnylam Pharmaceuticals IncDirector EpidemiologyCambridge, MAIn this role, you will work closely with Clinical Research, Global Patient Safety and Risk Management (GPSRM), Regulatory Affairs, and Biostatistics to inform clinical development and answer product- and disease-area research questions for Alnylam RNAi therapeutics using observational studies and real-world evidence. The Director Epidemiology is responsible for representing the Epidemiology function at Alnylam, providing expertise, strategic vision, and oversight of epidemiology and real-world evidence (RWE) activities in support of all clinical development programs and marketed RNAi therapeutics.
Genentech IncSenior ADS Programmer Genentech IncSenior ADS ProgrammerBoston, MA$114,000–$211,600 / yearIn addition to supporting regulatory submissions, the ADS Programmer plays a critical role in generating data insights through platforms such as the Insight Engine, enabling real-time exploration and interpretation of diverse clinical and exploratory data. We identify, influence, and adopt industry-leading digital and automation solutions, develop analytical approaches to support exploratory analyses, and align statistical programming practices across both early- and late-stage clinical development.
Kymera TherapeuticsAssociate Director, Statistical Programming Kymera TherapeuticsAssociate Director, Statistical ProgrammingWatertown, MA$160,000–$240,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Manage multiple tasks, troubleshoot technical and project issues, and assist with the infrastructure development of the department; Evaluate and implement innovative tools and programming technologies to streamline processes and improve team efficiency and quality.
Beam Therapeutics IncSenior Manager, Statistical Programming Beam Therapeutics IncSenior Manager, Statistical ProgrammingCambridge, MAManages the activities of data summary, statistical analysis, patient profile, safety and efficacy tables, listings and figures using Base SAS, SAS Macros, SAS/STAT, SAS/Graph, SAS/SQL, SAS/ODS and R. The senior manager will be responsible for developing and maintaining statistical programming functions within a therapeutic area to support various clinical studies and submissions to ensure successful execution for Beam's clinical programs.
Beam TherapeuticsSenior Manager, Statistical Programming Beam TherapeuticsSenior Manager, Statistical ProgrammingCambridge, MA$155,000–$190,000 / yearManages the activities of data summary, statistical analysis, patient profile, safety and efficacy tables, listings and figures using Base SAS, SAS Macros, SAS/STAT, SAS/Graph, SAS/SQL, SAS/ODS and R. Beam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA.
BeOne Medicines LtdSenior Manager, Scientific Programming BeOne Medicines LtdSenior Manager, Scientific ProgrammingCambridge, MA$144,400–$189,400 / yearEssential Duties & Responsibilities: Develop, validate and maintain analysis-ready datasets, tables, figures and listings for observational and RWE studies derived from diverse real-world data sources, including claims, electronic health records (EHRs) and registry data. Write, test and validate programs to produce analysis datasets, TLFs and presentation output, to be included in reports for submission to regulatory agencies, publications and other communications as needed.
Amylyx Pharmaceuticals IncAssociate Director, Clinical Data Programmer Amylyx Pharmaceuticals IncAssociate Director, Clinical Data ProgrammerCambridge, MARemoteThis individual will work collaboratively cross-functionally to provide hands-on data management support, programming support and technical leadership to develop, maintain, validate the clinical database, and run computer programs that access, visualize, and report clinical trial data, in accordance with various clinical plans, ICH guidelines, and applicable regulatory requirements. • Supports leading data management activities (i.e. DMP creation, CRF creation, edit checks creation, database lock), assisting with database setup, conduct and closeout phases.
ZSStrategy Insights & Planning Associate Consultant - HEOR Value and Evidence Communication ZSStrategy Insights & Planning Associate Consultant - HEOR Value and Evidence CommunicationBoston, Massachusetts
AstraZeneca PlcExecutive Medical Director, Hematology AstraZeneca PlcExecutive Medical Director, HematologyBoston, MATypically leading 2 program teams and drive the successful execution of clinical studies / programs / research strategies; define and manage the benefit to risk profile of our products Representing Clinical Development on the Global Program Team (GPT) and Global Medicine Team in presentations at management and review committees (e.g., Clinical Document Review Committee, Development and Commercial Steering Committee); advance understanding of the impact our therapies have on the pathophysiology of rare and orphan diseases through scientific discourse and interpretation of data Fostering development of Medical Directors and CDS and/or fellows. or equivalent 7+ years of experience in clinical development; clinical research, global regulatory, and product development expertise Has prepared documents and attended regulatory meetings with FDA and other regulatory agencies Experience designing and executing multinational clinical trials required Demonstrated ability to lead cross-functional teams to define clinical strategy and clinical study design Experience supporting business development activities M.D.
Harvard UniversityHMS - Postdoctoral Fellow in Biomedical Informatics (Farhat Lab) Harvard UniversityHMS - Postdoctoral Fellow in Biomedical Informatics (Farhat Lab)Cambridge, MAThe Farhat Lab in the Department of Biomedical Informatics is seeking a highly motivated 'dry lab postdoctoral research fellow interested in pursuing innovative studies in the field of infectious disease genomics and its translation to the clinic. Salary Range Information regarding postdoctoral fellow salary which is determined by the number of years post PhD can be found at http://postdoc.hms.harvard.edu/guidelines.
Joslin Diabetes CenterHealthcare Data Analyst (Clinic Administration) Joslin Diabetes CenterHealthcare Data Analyst (Clinic Administration)Boston, MAThis requires experience working with databases, establishing data connections and running queries, aggregating and synthesizing data for business plans, trends, and projections, along with creativity, curiosity, and initiative to evolve the tools and reporting systems to meet the priorities of a dynamic healthcare environment. Strong experience in data management and analytic tools and techniques; Strong experience in report writing, analytics, visualizations, dashboard creation; Strong experience demonstrating analytical, financial, qualitative and quantitative skills.
Beam TherapeuticsSenior Director, Global HEOR Beam TherapeuticsSenior Director, Global HEORCambridge, MA$260,000–$320,000 / yearProvide operational oversight of Medical Affairs evidence generation, including vendor/CRO governance, milestone/deliverable tracking, data‑quality plans, risk management, and on‑time execution across Medical Affairs–led studies; contribute to long‑term capability building (digital health, real‑world studies). Support business decisions around ex-US strategy including, but not limited to, scoping ex-US opportunities, prioritizing country engagement, early scientific advice / parallel consultations with EMA and HTA bodies (e.g., HTACG/JSC), providing advice to development programs on endpoint selection to support product and reimbursement approvals ex-US, etc.
MMSStudy Design Statistician (Remote) MMSStudy Design Statistician (Remote)Boston, MARemoteFull timeWorking alongside innovative statisticians you will be responsible for leading the full life-cycle of KerusCloud support and statistical services, from: Assisting customers with their study design with a particular focus on simulation with KerusCloud to ensure they are aligned with the study objectives. As part of our Strategic Statistical Services Arm, this is a full-time role with emphasis on being an internal and external SME for clinical trial design, together with providing consultation to advise clients on a range of broader statistical issues, and will have an internal job title of Strategic Statistician.
BOSTON PUBLIC HEALTH COMMISSIONNewWastewater Fellowship BOSTON PUBLIC HEALTH COMMISSIONWastewater FellowshipBoston, MAThe Wastewater Epidemiology Fellow will coordinate with internal and external partners to integrate data from the Wastewater Monitoring Program with other public health surveillance data to enhance awareness, preparedness, and response to infectious disease. The Boston Public Health Commission does not have a laboratory and contracts with third-party laboratories to perform analyses and third-party technicians to collect wastewater, so this is not a laboratory or field-work position.
Dyne Therapeutics IncDirector, Global Health Economics & Outcomes Research HEOR Dyne Therapeutics IncDirector, Global Health Economics & Outcomes Research HEORWaltham, MAPrimary Responsibilities: Informing development strategies from HEOR / market access perspective Represent the HEOR and market access perspective in internal clinical development and regulatory forums Provide critical input into clinical development plans, including protocol design, endpoint selection, and other aspects of clinical trial evidence generation, to ensure alignment with future payer and HTA expectations Communication of value to payers and HTA bodies Lead development of AMCP dossiers for US payers Lead development of cost-effectiveness models for NICE and other HTA bodies requiring formal cost-effectiveness analyses Serve as a core team member for HTA submissions outside the US, with responsibility for shaping and stress-testing value narratives included in pricing and reimbursement dossiers and interpreting and recommending evidence to support such narratives, in a way that optimizes both credibility and relevance for payer decision-making Make substantial contributions to other payer communication materials (e.g., Medical Value Liaison slide decks) and launch readiness activities as needed Leading real-world evidence strategy and execution of real-world analyses Lead planning of real-world evidence generation activities to address evidence gaps as needed for informing decision-making by payers, HTA bodies, and clinicians Oversee execution of real-world data analyses, ensuring analytical rigor and fitness for purpose Interpret and translate results from real-world analyses into peer-reviewed publications and other external communications intended to meaningfully inform clinical practice and payer/HTA decision-making. Accordingly, the Director, Global HEOR, helps shape development plans, evidence strategies, and value narratives so that they align with how payers and health technology assessment (HTA) bodies make decisions, balancing analytical rigor with a clear focus on what is relevant for decision-making.
Alexion Pharmaceuticals IncSenior Medical Director Clinical Development Neurology Alexion Pharmaceuticals IncSenior Medical Director Clinical Development NeurologyBoston, MA$280,895.20–$421,342.80 / yearYou will be responsible for: Serve as subject medical expert and clinical development leader accountable for 2 (or more) programs, including but not limited to the preparation and execution of a clinical development strategy and related documents including protocols, charters, statistical summary reports, meeting presentations, publications, and clinical sections of regulatory documents. This is a therapeutic area role and is specifically designated to provide medical leadership and input to Program Teams across drug development (i.e., transitioning molecule through IND/CTA and First in Human study stage to Proof of Concept /Phase2 stage, Phase 3 and regulatory approval ).
Parabilis MedicinesAssociate Director, Data Science, Computational Biology Parabilis MedicinesAssociate Director, Data Science, Computational BiologyCambridge, MA$175,000–$220,000 / yearStrategic thinker, planner and implementer of computational biomarker and translational analyses for early‑phase oncology studies (e.g., FOG‑001 and ERG/AR degraders), from IND‑enabling work through Phase 1/2, ensuring continuity between preclinical and clinical datasets. Design and execute analysis plans for diverse biomarker modalities across preclinical models and clinical samples, including bulk and single‑cell RNA‑seq, DNA panels/WES, ctDNA, IHC/IF, multiplex protein assays, and other exploratory readouts.