Executive Director, Computational Systems Biology Revolution Medicines, Inc.Executive Director, Computational Systems BiologyRedwood City, CA$265,000–$331,000 / yearThe individual will lead a team of computational biologists and bioinformaticians focused on acquisition, organization, and analysis of large multi-omics data sets, using both public and proprietary data sources, that will help inform treatment strategies and guide patient stratification for a growing pipeline of RAS(ON) and targeted oncology therapeutics. The company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Executive Director, Computational Systems Biology Revolution MedicinesExecutive Director, Computational Systems BiologyRedwood City, California$265,000–$331,000 / yearThe individual will lead a team of computational biologists and bioinformaticians focused on acquisition, organization, and analysis of large multi-omics data sets, using both public and proprietary data sources, that will help inform treatment strategies and guide patient stratification for a growing pipeline of RAS(ON) and targeted oncology therapeutics. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Computational Scientist II LancesoftComputational Scientist IISouth San Francisco, CA$45Prior exposure to LLM applications is a big plus whether through building and deploying LLM-powered pipelines, working with agentic frameworks such as LangSmith, retrieval-augmented generation (RAG) architectures, harness engineering or guardrail design, or integrating LLM APIs into functional tools. You will work at the interface of AI engineering and quantitative pharmacology, partnering closely with M&S Scientists and Clinical Pharmacologists to develop tools that are scientifically grounded, reliable, and impactful.
Computational Scientist II - Single Cell Genomics Dawar ConsultingComputational Scientist II - Single Cell GenomicsSouth San Francisco, CaliforniaThis role will involve analyzing large-scale sequencing datasets, developing computational pipelines, and collaborating with multidisciplinary teams to generate biological insights that support drug discovery. Analyze and interpret large-scale single-cell sequencing datasets (scRNA-seq) generated from high-content perturbation experiments.
Postdoctoral Researcher, ML for Biology, Hsu Lab Arc InstitutePostdoctoral Researcher, ML for Biology, Hsu LabPalo Alto, CAYou will have the opportunity to collaborate widely across Arc, Stanford, and the broader Bay Area ecosystem, with access to strong platforms in our lab and our institutions for genomics, single-cell technologies, synthetic biology, high-performance computing clusters, and experimental model systems. Our two Institute Initiatives reflect this model in action: Virtual Cell Initiative : Building a full-stack virtual cell model to identify disease mechanisms and nominate drug targets, accelerating the path from biological insight to clinical trials.
Forward Deployed Research Scientist (Biology) GoodfireForward Deployed Research Scientist (Biology)San Francisco, California$220,000–$315,000 / yearProject delivery and implementation – own research delivery on high-stakes projects with customers and do whatever it takes to make delivery successful, including: problem and hypothesis definition, data sourcing, tool building, iteration, and implementation. Treating models as black boxes is an unnecessary handicap—we have access to the structures inside them, and understanding those structures lets us steer what models learn, make them safer and more useful, and extract the vast knowledge they contain.
Director, Machine Learning, Alzheimer's Disease Initiative Arc InstituteDirector, Machine Learning, Alzheimer's Disease InitiativePalo Alto, CA$338,500–$400,500 / yearSupport: Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction. This ambitious initiative spans Arc's Technology Centers and Core Investigator Laboratories and focuses on high-throughput interrogation of neurodegeneration and Alzheimer's disease mechanisms using advanced gene editing and functional genomics approaches.
Senior Computational Scientist – Systems Biology & Next‑Gen Data Engineering CalliereSenior Computational Scientist – Systems Biology & Next‑Gen Data EngineeringUnion City, CaliforniaYou’ll join a tight-knit team of scientists and engineers decoding huge multi‑omic datasets to uncover patterns that actually change patient outcomes. If you’re driven by the idea of building tools that help decode biology at scale and you thrive where data meets diagnostics, this is your stage.
Scientist I, Disease Biology Altos LabsScientist I, Disease BiologySan Francisco, CA$134,700–$172,700 / yearAbility to maintain cooperative working relationships with a broad range of people, including staff colleagues, lab members, faculty, outside agencies and collaborators, and the community. In this role you will develop physiologically relevant in vitro and ex vivo disease models and integrate these with in vivo studies to identify interventions that reverse disease-associated cell states.
Computational Protein Designer Latent LabsComputational Protein DesignerSan Francisco, CaliforniaUsing your blend of computational expertise and in-depth biochemical understanding of proteins, you will generate insights to improve protein functionality and operate at the interface between our machine learning and experimental platform units, working closely to seamlessly integrate AI generations and lab validation data. You have a proven track record of running protein design campaigns end-to-end, successfully leveraging novel computational tools and knowledge of biochemistry or structural biology to design proteins to functional requirements and applications in synthetic biology.
Data Scientist, RNA Biology South San Francisco, Ca ESRhealthcare and EXEC STAFF RECRUITERSData Scientist, RNA Biology South San Francisco, CaSan Francisco, CaliforniaYou will lead the curation of RNA-focused datasets for ML training and validation, discover statistical patterns in our large-scale datasets evaluating RNA structure and RNA-small molecule interactions, and devise and implement new strategies to test the accuracy of our ML models. As a full-time Data Scientist on the Machine Learning team, you will work closely with scientists and engineers to apply and advance our technology platform for RNA structure prediction, target identification, and early-stage drug discovery.
Application Scientist MithrlApplication ScientistSan Francisco, CaliforniaThis role requires a PhD level scientist with strong expertise in discovery biology, computational biology, or a related field, combined with excellent communication skills and a passion for working directly with customers and partners. You will design and run analyses inside Mithrl, build publication-quality narratives and figures, and support discovery programs across biomarker identification, target discovery, target validation, and early preclinical development.
Principal Scientist, Translational Genetics CytokineticsPrincipal Scientist, Translational GeneticsSouth San Francisco, California$202,500–$236,250 / yearCytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction. Analyze and integrate multi-omics data (genomics, transcriptomics, proteomics, metabolomics) to identify causal variants and pathways associated with cardiovascular diseases.
NewComputational Biologist Arcadia ScienceComputational BiologistEmeryville, CA$150,000–$200,000 / yearYou'll work closely with the platform scientists and engineering team, quickly and iteratively translating research-grade code and methods into something usable, testable, and ready to openly release. We're looking for several PhD-level computational scientists to help develop our bioinformatic tools into scalable products that are rigorous and useful for a wide range of researchers.
Senior Research Scientist MastarRecSenior Research ScientistSan Francisco, CaliforniaMastarRec is recruiting a Senior Research Scientist to support biotechnology and life sciences organizations across the United States to join our cutting-edge research team driving innovation in genomics, transcriptomics, and multi-omics data analysis. In this role, you will lead the development of scalable computational methods, analyze next-generation sequencing (NGS) datasets, and collaborate with interdisciplinary teams across biotechnology, clinical research, and personalized medicine.
Clinical Translational Scientist Valius SciencesClinical Translational ScientistSan Francisco, CaliforniaAt Valius, we believe that the future of cancer care will be defined by “maximalist” diagnostics: deep, comprehensive assessments of DNA, RNA, and protein designed to give patients and their care teams the best possible understanding of how their tumor works and what its vulnerabilities are. This is a non-traditional translational scientist role: you’ll operate at the intersection of oncology, molecular genomics, and clinical evidence interpretation, delivering high-trust guidance that is scientifically rigorous, clinically grounded, and compassionate.
Scientist II, Translational Research TempusScientist II, Translational ResearchRedwood City, CA$90,000–$135,000 / yearDemonstrated ability to influence without authority (both with internal and external stakeholders Proactive mindset that bridges ideas to implementable solutions, and can help move both internal and external stakeholders to quickly solve problems Experience with communicating insights and presenting concepts to diverse audiences. Work with Product and Engineering teams to streamline workflow of computational analyze Contribute to the development of the portfolio by providing feedback to leadership regarding client responses and suggestions; maintain a solution-oriented mindset.
Senior Scientist I, Translational Research TempusSenior Scientist I, Translational ResearchRedwood City, CA$100,000–$160,000 / yearDemonstrated ability to influence without authority (both with internal and external stakeholders Proactive mindset that bridges ideas to implementable solutions, and can help move both internal and external stakeholders to quickly solve problems Experience with communicating insights and presenting concepts to diverse audiences. Work with Product and Engineering teams to streamline workflow of computational analyze Contribute to the development of the portfolio by providing feedback to leadership regarding client responses and suggestions; maintain a solution-oriented mindset.
Senior Director - Biointelligence Amgen Inc.Senior Director - BiointelligenceSouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. This role requires a leader with deep expertise in machine learning for biological systems, experience building and mentoring high-performing scientific teams, and a track record of translating advanced computational methods into impactful research capabilities.
Scientist II, Translational Research Tempus AIScientist II, Translational ResearchRedwood City, California$90,000–$135,000 / yearDemonstrated ability to influence without authority (both with internal and external stakeholders Proactive mindset that bridges ideas to implementable solutions, and can help move both internal andexternal stakeholders to quickly solve problems Experience with communicating insights and presenting concepts to diverse audiences. Work with Product and Engineering teams to streamline workflow of computational analyze Contribute to the development of the portfolio by providing feedback to leadership regarding clientresponses and suggestions; maintain a solution-oriented mindset.