Associate Director, Clinical Research Operations Dana-Farber Cancer Institute IncAssociate Director, Clinical Research OperationsBOSTON, MA$129,500–$150,200 / yearProficiency with clinical research and healthcare technology systems, including electronic medical record systems (such as EPIC), clinical trial management systems (specifically OnCore), electronic protocol and regulatory compliance tracking systems (such as iRIS), electronic data capture platforms (like RedCap), financial and HR systems (WorkDay), and advanced Microsoft Office and data analysis tools, with meticulous attention to detail and the ability to manage multiple high-priority initiatives simultaneously. As a senior leader, the Associate Director builds and develops high-performing teams, fosters a culture of collaboration, accountability, innovation, and continuous improvement, and serves as the department's primary representative for clinical research initiatives within the institution and across external research networks.
Executive Director Clinical Operations, Program Management (Cell Therapy) AstraZeneca PlcExecutive Director Clinical Operations, Program Management (Cell Therapy)Cambridge, MA$270,188.80–$405,283.20 / yearAccountabilities: Franchise Leadership: Clinical Operations Strategy: Define and implement short- and long-term clinical operations strategies across franchises, including therapeutic operating models, country footprint and site strategies, and consistent, deliverable operational clinical development plans. Cross-Functional Integration: Build deep partnerships with shared functions (Data Management, Vendor Management, Lab Management groups, Logistics, Manufacturing) to co-create and execute fit-for-purpose cell therapy strategies.
Clinical Operations Manager Tessera TherapeuticsClinical Operations ManagerSomerville, MA$164,000–$199,000 / yearYou have previously demonstrated ability to partner with and proactively manage internal stakeholders, CROs, and vendors, and collaborate cross-functionally to deliver global clinical trials according to the planned timelines and budget, while ensuring quality in accordance with ICH-GCP guidelines and regulatory requirements. Bachelor's degree in a relevant scientific or healthcare discipline, with 8+ years of clinical operations experience, including 4+ years as a clinical trial manager, leading cross-functional teams and accountable for planning and executing global clinical trials.
NewClinical Study Operations Manager Beacon BiosignalsClinical Study Operations ManagerBoston, MassachusettsRemoteAs such, we're always seeking new contributors whose work demonstrates an avid curiosity, a bias towards simplicity, an eye for composability, a self-service mindset, and - most of all - a deep empathy towards colleagues, stakeholders, users, and patients. As a Clinical Study Operations Manager within the Clinical Study Operations team, you will be responsible for ensuring the successful operational delivery of Beacon’s clinical studies, from startup through close-out.
Clinical Operations Manager Tessera Therapeutics IncClinical Operations ManagerSomerville, MA$164,000–$199,000 / yearYou have previously demonstrated ability to partner with and proactively manage internal stakeholders, CROs, and vendors, and collaborate cross-functionally to deliver global clinical trials according to the planned timelines and budget, while ensuring quality in accordance with ICH-GCP guidelines and regulatory requirements. Bachelor's degree in a relevant scientific or healthcare discipline, with 8+ years of clinical operations experience, including 4+ years as a clinical trial manager, leading cross-functional teams and accountable for planning and executing global clinical trials.
Associate Director, Clinical Operations Kymera TherapeuticsAssociate Director, Clinical OperationsWatertown, MA$160,000–$240,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Work closely with translational medicine team to ensure appropriate incorporation of bioanalytical sampling plan into clinical protocols and relevant data output of the trial is provided to functional groups for review.
Associate Director/Director, Clinical Operations Compliance Scholar RockAssociate Director/Director, Clinical Operations ComplianceCambridge, MAServe as the Clinical Operations compliance subject matter expert for SOPs, GCP, ICH, FDA, EMA, and other applicable regulatory requirements, ensuring practical application/compliance across study teams and vendors throughput the trial lifecycle. Scholar Rock is a late-stage global biopharmaceutical company focused on developing and commercializing apitegromab for children and adults with spinal muscular atrophy (SMA) and other rare, severe, and debilitating neuromuscular diseases.
Clinical Operations Manager Verily Life Sciences LLCClinical Operations ManagerBoston, MAThe Clinical Operations Manager owns critical study documentation, risk management strategy, site selection and qualification, monitoring oversight, and safety/deviation workflows from study start-up through to study close-out, collaborating within cross-functional teams to drive successful end-to-end study execution. Serve as the primary contact for clinical sites, managing site operations, protocol deviations, adverse event evaluations, and IRB reporting; and, oversees electronic Trial Master Files (eTMFs) to ensure full GCP compliance, regulatory adherence, and continuous audit readiness.
Associate Director, Clinical Operations Compliance Scholar Rock Holding CorpAssociate Director, Clinical Operations ComplianceCambridge, MA$175,000–$225,000 / yearServe as the Clinical Operations compliance subject matter expert for SOPs, GCP, ICH, FDA, EMA, and other applicable regulatory requirements, ensuring practical application/compliance across study teams and vendors throughput the trial lifecycle. Scholar Rock is a late-stage global biopharmaceutical company focused on developing and commercializing apitegromab for children and adults with spinal muscular atrophy (SMA) and other rare, severe, and debilitating neuromuscular diseases.
AD/Director, Clinical Operations Compliance StratAcuity Staffing Partners IncAD/Director, Clinical Operations ComplianceCambridge, MA$110–$150 / hourThis individual will partner closely with Clinical Operations, Quality, Regulatory, Data Sciences, Pharmacovigilance, and Clinical Research teams to ensure inspection readiness, strengthen operational processes, and drive compliance excellence across clinical programs. In terms of professional development, Everforth Apex hosts an on-demand training program, provides access to certification prep and a library of technical and leadership courses/books/seminars once you have 6+ months of tenure, and certification discounts and other perks to associations that include CompTIA and IIBA.
Director, Clinical Operations Whoop IncDirector, Clinical OperationsBoston, MA$210,000–$230,000 / yearLead operational oversight of CROs, technology vendors, recruitment partners, and other external service providers, establishing scalable governance frameworks, performance metrics, and escalation pathways to ensure high-quality delivery and accountability. Oversee Clinical Data Management and clinical trial technologies, ensuring high-quality, timely, and compliant data collection, management, and delivery across systems including EDC, CTMS, eConsent, ePRO, eTMF, and remote study platforms.
Associate Director - Clinical Operations Monte Rosa Therapeutics IncAssociate Director - Clinical OperationsBoston, MADemonstrated experience with developing clinical operations strategy and plans including site monitoring, risk mitigation plans, recruitment plans, enrollment modeling and CRO/vendor oversight plans. Monte Rosa Therapeutics is seeking a highly experienced Clinical Operations professional to lead the successful planning, implementation, and conduct of clinical trials across multiple indications.
Associate Director, Clinical Operations Summit Therapeutics IncAssociate Director, Clinical OperationsCambridge, MA$170,000–$198,000 / yearHARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI. Drafts, reviews and approves internal and external study-related plans, processes, and documents including Informed Consent Forms, Investigator Agreements (CTA), CRFs, CRF Guidelines, statistical/pharmacokinetic analysis plans, monitoring plans, data management plans, and safety monitoring activities.
NewDirector, Clinical Operations Viridian Therapeutics IncDirector, Clinical OperationsWaltham, MAReporting to the VP, Clinical Operations, the Director, Clinical Operations is responsible for leading projects to support the execution of clinical studies aligned with the clinical development plan according to the agreed upon timelines and budgets. Provide operational leadership for cross-functional study teams and serve as one of the lead Clinical Operations representative for assigned programs.
NewManager, Clinical Study Operations Beacon Biosignals IncManager, Clinical Study OperationsBoston, MA$115,000–$135,000 / yearManage Beacon''s day-to-day working relationship with sponsors - and, where applicable, a CRO intermediary - on the studies your direct reports run, and step in to represent Beacon directly with the sponsor when a study lead escalates a decision that needs strategic alignment or sign-off. You are expected to bring hands-on clinical trial operations experience - enough to guide your direct reports through site and vendor issues, coach sound day-to-day tradeoffs, and step in directly on complex or high-stakes situations when needed.
Associate Director, Clinical Operations - Oncology Moderna IncAssociate Director, Clinical Operations - OncologyCambridge, MA$142,500–$256,500 / yearWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. This position will be responsible for initiating and leading clinical trials across all phases, including overseeing CROs and vendors and working cross-functionally on clinical operations strategy and related initiatives.
Clinical Operations Manager NanopathClinical Operations ManagerCambridge, MAThis role combines strategic clinical operations leadership with hands-on operational execution , supporting study start-up, site initiation, monitoring, and ongoing study management. At Nanopath we are dedicated to building a diverse and inclusive workplace, so if you’re excited about this role but your past experience doesn’t align perfectly with every point in the job description, we encourage you to apply anyways.
Director, Clinical Operations Oruka Therapeutics, Inc.Director, Clinical OperationsWaltham, MA$213,000–$240,000 / yearSignificant experience with cross-functional leadership and clinical teams, including leading data review, protocol deviation review, database lock, CSR development, and study reporting activities. Role Overview: We are seeking an exceptionally nimble and flexible Director of Clinical Operations who has a track record of achievement across all aspects of trial setup and execution in a fast paced small biotech with limited infrastructure and resources.
Associate Director – Clinical Operations Monte Rosa Therapeutics, IncAssociate Director – Clinical OperationsBoston, MassachusettsFull timeOverview: Monte Rosa Therapeutics is seeking a highly experienced Clinical Operations professional to lead the successful planning, implementation, and conduct of clinical trials across multiple indications. • Demonstrated experience with developing clinical operations strategy and plans including site monitoring, risk mitigation plans, recruitment plans, enrollment modeling and CRO/vendor oversight plans.
Executive Director, Clinical Operations Lahey Hospital and Medical CenterExecutive Director, Clinical OperationsMA$190,000–$250,000 / yearThe position will directly manage a portfolio of high-priority enterprise initiatives, coordinate the CCO's leadership forums including joint CMO/CNO governance meetings, oversee budget management and financial reporting for the OCCO, and lead the performance management cycle including quality dashboards, KPI tracking, and leadership evaluations. This role requires an exceptional leader who combines executive-level business acumen with deep healthcare operational knowledge, the ability to build and maintain trusted relationships across all levels of the organization, and the discipline to drive accountability and execution in a large integrated health system.