NewAssociate Principal Scientist, In Vivo Pharmacology, Oncology Merck & Co IncAssociate Principal Scientist, In Vivo Pharmacology, OncologyBoston, MA$144,800–$227,900 / yearRequired Skills: Immunoassays, Immunohistochemistry (IHC), Immunology, In Vivo Models, In Vivo Studies, Mass Spectrometry Imaging, Molecular Biology, Mouse Models, Multiplex Assays, Oncology, Pharmacodynamics, Pharmacokinetics, Pharmacology, Preclinical Research, Tumor Biology. EDUCATION: PhD in Oncology, Pharmacology, Biology, Pharmaceutical Sciences, Chemistry, Immunology, Biotechnology, Molecular and Cell Biology, or related STEM field with 5+ years of industry / biotech experience in Oncology drug discovery, or an MS with 7+ years of experience, or a BS with 10+ years of experience.
Lead Scientist – Microgravity Fluidics / Microfluidics Revolution SpaceLead Scientist – Microgravity Fluidics / MicrofluidicsBoston, MassachusettsRevolution Space is seeking an experienced and highly motivated Lead Scientist with deep expertise in microgravity fluidics, microfluidics, and capillary-driven fluid systems to lead research, development, and experimental efforts for next-generation fluidic technologies. Lead scientific research and development initiatives related to microgravity fluidics, microfluidics, and capillary flow systems.
Research Leader / Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MA Isomorphic LabsResearch Leader / Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MACambridge, MAAct as a vital bridge between computational prediction and experimental reality, collaborating closely with: ML and Data Science Teams: To translate in silico predictions into physical validation protocols and provide clean data loops to train future models, iteratively improving the predictive accuracy of our proprietary drug design platform. These are exciting opportunities to work closely with world leading ML and drug discovery experts to develop imaginative new ways to test biological hypotheses, building a deep mechanistic understanding of drug target interactions in disease to drive our projects forward.
Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA Isomorphic LabsResearch Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MACambridge, MAProven track record of project leadership / leading medicinal chemistry efforts on drug discovery projects, demonstrating significant contributions to project progression (ideally from hit identification through to lead optimisation or candidate nomination), with familiarity of optimisation of ADME properties. Rapidly drive drug discovery programs to value inflection points by deploying your knowledge of modern discovery principles and synthetic organic chemistry, taking ownership as either an overall Project Lead or Medicinal Chemistry Lead.
Advanced Process Analytics Scientist Integrated Resources, IncAdvanced Process Analytics ScientistCambridge, MassachusettsContractorThis includes but not limited to developing tools for deeper understanding of the underlying biological phenomena that lead to differences in product quality (e.g., via metabolic flux modeling, proteomics modeling, bio-informatics); develop robust spectral models correlating to valuable metabolites, cell mass, and product quality attributes (e.g., chemometric models for NIR, Raman). To reach that goal, we are exploring the application of state of the art data science and machine learning while leveraging available process knowledge and a wealth of development and manufacturing data to build end to end product quality predictive meta-models.
Associate Scientist-II Integrated Resources, IncAssociate Scientist-IICambridge, MassachusettsFull timeThe successful candidate will have hands-on experience with a variety of biochemical methods relevant for the study of neurodegenerative diseases and the ability to utilize these methods for target engagement studies to support drug discovery and development projects. As Associate Scientist II, the expectation is that the incumbent is capable of planning and executing experiments with limited supervisorial oversight including the analysis and interpretation of the experimental results to achieve agreed upon objectives.
Analytical Development Senior Scientist Vertex PharmaceuticalsAnalytical Development Senior ScientistBoston, MassachusettsThe position is part of the Chromatography Subject Matter Expert (SME) team , focused on small molecules and synthetic peptides/oligonucleotides , with particular emphasis on drug substance, drug product intermediates, and drug product . At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Associate Scientist, Protein Engineering Zealand Pharma A/SAssociate Scientist, Protein EngineeringCambridge, MA$85,000–$125,000 / yearCombining more than 25 years of peptide R&D expertise with a proprietary data platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead a new era in obesity and metabolic health. The site is a highly collaborative, multidisciplinary discovery hub integrating computational research, chemistry, and biology, and is deeply connected to the Greater Boston life sciences ecosystem.
Clinical Program Scientist Integrated Resources, IncClinical Program ScientistLexington, MassachusettsContractorLeads cross functional teams and is responsible for the oversight and management of study timelines as well as the financial management of a study. Ability to manage and communicate effectively with research vendors including reviewing requests for proposals, analyzing scope of work, and responding to inquiries and complaints.
Scientist I Integrated Resources, IncScientist ICambridge, MassachusettsContractorThe abilities to manage several projects simultaneously, work both independently and collaboratively within a team environment, design and execute experiments, interpret data, and effectively communicate in written and oral forms are essential. • Areas of specialization should reside in the fields of separation science, structure elucidation and characterization approaches as applied towards small molecule drug substances and/or process development.
QC Microbiology Scientist Integrated Resources, IncQC Microbiology ScientistAndover, MassachusettsContractorPerforms traditional microbiology testing (Bio burden, endotoxin) in support of commercial product release testing. Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms.
NewMedical Lab Scientist II - Day Shift Boston Children's HospitalMedical Lab Scientist II - Day ShiftBoston, MAKey Responsibilities: Performing a variety of moderate and highly complex and diagnostic laboratory testing under general supervision in the laboratory. Minimum Qualifications: Associate’s degree AND successful completion of an ASCP/NAACLS accredited Medical Technology/Medical Laboratory Science program required.
Medical Lab Scientist I - Overnight Boston Children's HospitalMedical Lab Scientist I - OvernightBoston, MAKey Responsibilities: Performing a variety of moderate and highly complex and diagnostic laboratory testing under general supervision in the laboratory. Performing regularly scheduled quality control, preventative maintenance, and calibration of equipment according to laboratory guidelines.
Aseptic Control Principal Scientist, MSAT Vertex PharmaceuticalsAseptic Control Principal Scientist, MSATBoston, MassachusettsThis aseptic processing SME will partner with stakeholders to define strategies for microbial control of activities such as gowning, facility monitoring programs (EM, Water, Gases, etc.), disinfectant efficacy, aseptic processing simulations, filtration, particulate control, risk assessments, and will ensure the control strategies comply with industry guidance. Work closely with colleagues in Process development to design and implement new technologies for aseptic filling of cell therapy drug products in novel device platforms; this includes working closely with Contract Development and Manufacturing Organizations (CDMOs) and engineering firms to design processes and equipment needed to perform aseptic filling operations in a GMP environment.
Aseptic Control Principal Scientist, Msat Vertex Pharmaceuticals, IncAseptic Control Principal Scientist, MsatBoston, MA$145,500–$218,300 / yearThis aseptic processing SME will partner with stakeholders to define strategies for microbial control of activities such as gowning, facility monitoring programs (EM, Water, Gases, etc.), disinfectant efficacy, aseptic processing simulations, filtration, particulate control, risk assessments, and will ensure the control strategies comply with industry guidance. Work closely with colleagues in Process development to design and implement new technologies for aseptic filling of cell therapy drug products in novel device platforms; this includes working closely with Contract Development and Manufacturing Organizations (CDMOs) and engineering firms to design processes and equipment needed to perform aseptic filling operations in a GMP environment.
Senior Director, Safety Scientist Parabilis MedicinesSenior Director, Safety ScientistCambridge, MA$255,000–$300,000 / yearExperience authoring key safety documents, including Safety Surveillance Plans (SSPs), Signal Analysis Reports (SARs), Development Risk Management Plans (dRMPs), Development Core Safety Information (DCSI), and contributions to Investigator's Brochures (IBs), Development Safety Update Reports (DSURs), clinical protocols, and informed consent forms. This individual will play a critical role in the ongoing assessment of the benefit-risk profile of investigational products by leading signal detection, safety analyses, and risk management activities while partnering closely with Clinical Development, Regulatory Affairs, Biometrics, and Clinical Operations.
Research Scientist, Reinforcement Learning - Atlas Boston Dynamics, inc.Research Scientist, Reinforcement Learning - AtlasWaltham, MA$175,000–$230,000 / yearThe Atlas team is building next-generation whole-body mobile manipulation capabilities, and we are seeking a curious, driven Research Scientist to develop cutting-edge reinforcement learning (RL) solutions that run directly on our humanoid platforms. We are growing rapidly, building a commercial company that delivers cutting edge technology and solutions to our customers from industrial applications to logistics and warehouse solutions.
NewResearch Scientist, Inflammatory Bowel Disease (IBD) Drug Discovery 3316 Takeda Development Center AmericasResearch Scientist, Inflammatory Bowel Disease (IBD) Drug DiscoveryMassachusettsYour role: provides technical leadership for research project implementation and coordination, begins at the conception of new projects and helps advance to candidate selection, generates exciting and rigorous data that drive confident decisions, contributes critical thinking, technical expertise, and scientific insight to teamwork, and. The Gastrointestinal and Inflammation (GI2) Drug Discovery Unit at Takeda is building a new team of experienced, innovative, and collaborative researchers to deliver an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs.
NewAnalytical Principal Research Scientist Vertex PharmaceuticalsAnalytical Principal Research ScientistBoston, MassachusettsUnderstanding of key analytical deliverables for late-stage programs including method development, validation, specification setting, stability, release testing and analytical strategies to bring these individual items together collectively for a fast-paced program. While prior experience in dissolution is beneficial, we are seeking a candidate who demonstrates exceptional leadership potential, a commitment to continuous learning, and the ability to thrive in a fast-paced, dynamic environment.
Associate Scientist II Integrated Resources, IncAssociate Scientist IICambridge, MassachusettsContractorPossess significant expertise in animal models of neurodegenerative diseases, especially Alzheimer-related models, and experience with handling and dosing of rodents, tissues and fluids collection (CSF, plasma). The successful candidate will be involved with the design and execution of experiments to support the discovery of client drug targets and the development of small and large molecule drugs for the treatment of neurodegenerative diseases.