Director, Country Operations Management Alexion Pharmaceuticals IncDirector, Country Operations ManagementBoston, MA$162,566.40–$243,849.60 / yearEnsuring cross-functional collaboration of team and PMCOs through proactive communication with global study team members (Global Study Directors, Global Study Associate Directors, Global Study Managers), and other local study team members (Study Start-up Managers, Site Contract Associate Directors, Site Alliance Lead, Site Solutions Manager, CRAs, and ADCOM) to raise and resolve study specific blockers quickly. The DCOM is a key contributor in the overall deliverables for the country, including early planning, feasibility, site selection, study start-up, enrollment, data deliverables, and close-out, and works in partnership with global study team, SDHCO, Dir SSU and Site Partnership, and RHCO to define those deliverables.
NewSenior Manager/Associate Director, Quality Control Xenon PharmaceuticalsSenior Manager/Associate Director, Quality ControlNeedham, MassachusettsLead the assigned program’s stability activities, including trending, statistical evaluation, and scientific interpretation of stability data to assess product performance throughout its lifecycle, support shelf-life extensions and expiry dating justifications, and proactively identify and evaluate emerging stability risks and trends. Our Total Rewards program includes base salary, target bonus, and stock options, as well as a full range of benefits including medical, dental, vision, short-& long-term disability, accidental death & dismemberment, and life insurance programs, Employee Assistance Program, travel insurance, and retirement savings programs with company matching contributions.
NewSenior Manager/Associate Director, Enterprise Integration & Data Engineering Xenon PharmaceuticalsSenior Manager/Associate Director, Enterprise Integration & Data EngineeringNeedham, MassachusettsA bachelor’s degree or advanced degree in Information Systems, Computer Science, Data Engineering, Engineering, Business Administration, with a minimum of 7-10 year’s prior experience with enterprise integration, data engineering, middleware, cloud data platform, analytics platform, or enterprise applications experience; Experience in a corporate IT environment is preferred. Manage the implementation and maturation of Xenon’s enterprise integration and data engineering capabilities, including middleware/iPaaS, API-based integration, event/message-based integration, file-based ingestion, and ELT/data pipeline patterns.
NewDirector, Corporate Communications Xenon PharmaceuticalsDirector, Corporate CommunicationsNeedham, MassachusettsUnder the leadership of the Senior Vice President of Corporate Affairs, this role will also work with the CEO, CFO, CMO, CCO and other senior leaders to execute the Corporate and Investor Relations strategy, and effectively develop messaging and communications for our scientific, clinical, and financial progress to various stakeholder groups including investors, media and investigators. Lead development of corporate messaging and materials, including press releases, Q&As, corporate presentations, executive talking points, social media content, etc., in collaboration with Corporate Affairs, Brand Communications, the CFO, CEO, Medical Affairs, Clinical Development, Commercial, Legal, Regulatory, and other parts of the organization.
NewDirector, Medical Information Xenon PharmaceuticalsDirector, Medical InformationNeedham, MassachusettsThis role drives functional priorities for, and execution of medical inquiry management, scientific response content development, contact center operations, and digital medical information capabilities to support Medical Affairs, Clinical Development, and Commercial launch readiness. Our Total Rewards program includes base salary, target bonus, and stock options, as well as a full range of benefits including medical, dental, vision, short-& long-term disability, accidental death & dismemberment, and life insurance programs, Employee Assistance Program, travel insurance, and retirement savings programs with company matching contributions.
Account Director Layer HealthAccount DirectorBoston, MassachusettsThe work you will do directly influences how healthcare delivers safer, faster, and more equitable care to millions of people - reducing waste, unnecessary suffering, and preventable harm. 8+ years of experience in enterprise account management, strategic accounts, or partnerships within healthcare technology, SaaS, or data/AI platforms.
Director, Global Patient Safety Sciences - General Medicine Regeneron PharmaceuticalsDirector, Global Patient Safety Sciences - General MedicineCambridge, MA$205,000–$341,600 / yearDiscover your role: This Director position is directly responsible for all aspects of Global Patient Safety activities for assigned compounds and products in support of safety surveillance, signal management, communication of the safety profile as appropriate for the stage in the asset lifecycle, benefit risk assessment, safety responses to regulatory agency queries, safety documents (DSURs, PSURs, development RMPs, RMPs, etc.) and the review of clinical documents (Investigator Brochures, protocols, clinical study reports, etc.). Represent Global Patient Safety for assigned compounds on cross-functional teams, including Regeneron's Safety Oversight Committee (RSOC), Independent Data Monitoring Committees (IDMC), Strategic Program Team (SPT) and other teams with members external to Regeneron (alliance partners, CROs).
Director, Precision Medicine Regeneron Pharmaceuticals IncDirector, Precision MedicineCambridge, MA$205,000–$341,600 / yearAs a Director, a typical day may include the following: Program-level Precision Medicine lead that develops and implements the strategic vision for pharmacokinetic, pharmacodynamic, and exploratory biomarkers for clinical studies enabling indication and/or patient selection, early indication of biological activity, and to identify potential novel combinations. We are seeking to hire a Precision Medicine Scientific Lead to oversee the development and execution of biomarker strategies for novel cell therapies, cell transfer conditioning agents and combinations with bispecific antibodies across multiple disease areas (Oncology and Immunology).
Global Safety Program Lead/Sr Medical Director Alexion Pharmaceuticals IncGlobal Safety Program Lead/Sr Medical DirectorBoston, MA$280,895–$421,342 / yearLeads the safety physicians and scientists to support the safety strategy and input into the program design, monitoring, and data interpretation from pre-clinical and clinical studies, communication and post-marketing surveillance, epidemiology, pre-clinical and literature, epidemiology for each asset. Is accountable for project representation for Global Patient Safety at governance and other forums where safety is involved, eg DRC, eCRC, SARB, FSIRB, and DSMB/DMC, Medical Affairs Review Committees (MARC), product teams such CPT and GPT and Advisory Board meetings in partnership with GSH.
Senior Medical Director, Pharmacovigilance Karyopharm Therapeutics Inc.Senior Medical Director, PharmacovigilanceNewton, Massachusetts$310–$380Our lead therapy, XPOVIO® (selinexor), is a first-in-class inhibitor of exportin 1 (XPO1) and is approved in the U.S. for adults with relapsed or refractory multiple myeloma, with approvals in more than 50 countries and territories outside the U.S. We are also exploring opportunities to evaluate XPO1 inhibition across myeloproliferative neoplasms and TP53 wild-type driven solid tumors using next-generation compounds, including eltanexor. We are looking for talented people who are motivated by meaningful work, energized by growth and momentum, and excited by the opportunity to help shape what comes next in a collaborative, fast-moving environment where individual contributions are visible and valued.
Director, Physician Researcher - Evidence Generation & Registries Verily Life Sciences LLCDirector, Physician Researcher - Evidence Generation & RegistriesBoston, MAActing as a primary customer-facing expert, this leader will partner with health systems, academic investigators, payers, and pharmaceutical and other industry partners to design rigorous, operationally feasible studies and registries that demonstrate the clinical, operational, and population-level impact of products and programs. The ideal candidate combines deep clinical judgment, methodological fluency in observational and real-world evidence research, and the interpersonal skill to build trust with external partners while advancing Verily's scientific and business priorities.
Director, Patient Randomization Rate Iterative Scopes IncDirector, Patient Randomization RateCambridge, MA$160,000–$215,000 / yearYou'll use data to identify where patient volume, conversion, or operational processes are limiting performance, then design and test scalable solutions-from referral programs and community outreach to workflow improvements and external partnerships. We built a leading performance-driven network of 100+ sites across the US, Europe, India, and Australia, conducting research directly in the communities where care is delivered across gastrointestinal, hepatology, obesity, and cardiology.
Global Medical Director, Medical Affairs Dyne Therapeutics IncGlobal Medical Director, Medical AffairsWaltham, MA$215,000–$260,000 / yearThis individual translates clinical and scientific insights into actionable medical strategies, supports congress, symposia, advisory board, publication, medical education, and evidence generation activities, and helps strengthen Dyne's external scientific presence with healthcare professionals, key opinion leaders, payers, patient communities, and other stakeholders. The Global Medical Director partners closely with Clinical Development, Clinical Operations, Regulatory Affairs, Scientific and Medical Communications, Value and Access, Commercial, Patient Advocacy, regional medical teams, and external experts to ensure medical plans are aligned with corporate, program, product, and regional priorities.
Associate Director, Drug Product Technical Services (DPTS) Wave Life Sciences LtdAssociate Director, Drug Product Technical Services (DPTS)Lexington, MA$163,000–$221,000 / yearOur toolkit of RNA-targeting modalities includes editing, splicing, RNA interference and antisense silencing, providing us with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. Description: The Associate Director of DPTS leads drug product (DP) validation activities for Waves injectable assets in Phase 1-3 clinical trials and authoring of documents required for Regulatory submissions.
Senior Director, National Field Medical Lead Entrada TherapeuticsSenior Director, National Field Medical LeadBoston, MassachusettsRemoteWe are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families. Proven experience in working collaboratively and cross functionally across the enterprise of field medical teams, clinical development, commercial, sales, market access and other key functions and demonstrated ability to inform and shape company/product strategy.
Associate Director, GMP Quality Assurance Operations Kiniksa Pharmaceuticals International PlcAssociate Director, GMP Quality Assurance OperationsLexington, MAKiniksa is seeking an experienced Associate Director, GMP Quality Assurance Operations to be a key leader within the Quality organization, responsible for providing hands-on-Quality Operations oversight for GMP manufacturing activities supporting clinical programs. Responsibilities (including, but not limited to): Lead and execute GMP QA activities for development programs, including manufacture of master cell bank, working cell bank, drug substance and drug product/finished goods, in alignment with Kinika's Quality System.
Director, Biologics Development Dyne Therapeutics IncDirector, Biologics DevelopmentWaltham, MA$190,000–$230,000 / yearThe role will ensure the delivery of robust, scalable, and cost-effective second-generation manufacturing processes, serve as the primary technical lead for external CDMOs, driving aggressive timelines while delivering well-characterized products optimized for our proprietary bioconjugation platform. The Director applies deep scientific and industry expertise to solve complex challenges, influence decision-making, and enable successful program delivery that supports Dyne's mission of delivering meaningful outcomes for patients.
Director, Medical Writing Dyne Therapeutics IncDirector, Medical WritingCambridge, MA$190,000–$235,000 / yearThis role partners closely with Clinical Development, Clinical Operations, Clinical Pharmacology, Regulatory Affairs, Research, Preclinical, Translational Biomarkers, Program Management, and Medical Affairs to ensure clear, consistent scientific messaging across key submissions to the FDA and global health authorities. Author, edit, and collaborate with cross-functional team members on key documents, including protocols, investigator brochures, clinical study reports, CTD modules, briefing books, and related submission materials.
Director, Obesity Early Pipeline Commercial Development Pfizer IncDirector, Obesity Early Pipeline Commercial DevelopmentCambridge, MA$162,900–$271,500 / yearOperating as a cross-functional leader without direct line authority, the Director interprets business unit strategy to set priorities for covered programs, shapes early development strategy in partnership with R&D, advances assets through enterprise governance, and leads select strategic initiatives spanning the broader obesity portfolio. The Director owns commercial assessments end-to-end for covered programs - building product concepts and Target Product Profiles, developing disease-area strategies, and directing the integration of forecasting, pricing, HCP demand, future landscaping, and patient-flow insights into actionable commercial plans.
NewAssociate Director- Separations, Analytical Method Sciences (Ams) Bristol Myers SquibbAssociate Director- Separations, Analytical Method Sciences (Ams)Devens, MA$174,260–$211,160 / yearReporting to the Director of Analytical Method Sciences (AMS) in Analytical Science and Technology (AS&T) the Associate Director of Separations provides strategic and organizational leadership for the AMS Separations organization while maintaining deep expertise in analytical methodologies used to support commercial biologics testing and lifecycle management. The Analytical Method Sciences team partners across the global quality analytical science and technology organization to deliver quality separations methods and specifications to be used for commercial release and stability testing of our biopharmaceutical products.