Senior Medical Director Oncology Clinical Development Solid Tumors AbbVie IncSenior Medical Director Oncology Clinical Development Solid TumorsSouth San Francisco, CAActs as a clinical interface and actively solicits opinion leader interactions related to the molecule and disease area; partners with Medical Affairs, Commercial and other functions in these activities as required, consistent with corporate policies, to ensure that broad cross-functional perspectives are incorporated into Clinical Development Plans and protocols as appropriate. Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position.
Director Of Regulatory Affairs And Quality Assurance (RA / QA) Eight SleepDirector Of Regulatory Affairs And Quality Assurance (RA / QA)San Francisco, CAEvery role at Eight Sleep is a chance to create cutting-edge technology, collaborate with world-class talent, and help shape a future where sleep isn't passive, it's a powerful tool for living better. This role will provide leadership for risk management and oversee the operation of the quality management system, as well as serve as the primary interface between our company and regulatory agencies.
Director/Senior Director, Clinical Biomarkers GalapagosDirector/Senior Director, Clinical BiomarkersSan Francisco, CA$230,000–$300,000 / yearYou will help to define how we measure target and pathway engagement, pharmacodynamic response, and disease modification across our programs - and you will translate those insights into regulatory-grade evidence that supports our clinical and commercial strategies You will partner closely with other functions to integrate biomarker data into clinical programs and advance development, and you will have the opportunity to establish the Biomarker function as a core pillar of our development organization. Strong understanding of translational biology in autoimmune or inflammatory disease; familiarity with relevant disease mechanisms (e.g., cytokine networks, B/T cell biology, complement, innate immune pathways) is essential.
Senior Director, Clinical Success Abridge AI IncSenior Director, Clinical SuccessSan Francisco, CALead, mentor, and scale a team of Clinical Success Directors (MDs, DOs, PAs, NPs) and Nursing Clinical Success Directors (RNs, LPNs, etc.) focused on clinician enablement, change management, and adoption. Powered by Linked Evidence and our purpose-built, auditable AI, we are the only company that maps AI-generated summaries to ground truth, helping providers quickly trust and verify the output.
Senior Manager/Director Clinical Operations Lycia TherapeuticsSenior Manager/Director Clinical OperationsSouth San Francisco, CARemote$169,000–$198,000 / yearAbility to manage in a consensus environment through teamwork, trust and shared expectations, influencing strategic direction of complex global clinical operations issues, solicit information, listen well, persuade others, make important decisions and shape outcomes. Build, develop and train internal staff and external vendors, structure department for enhancing efficiency, and create a highly engaged work environment for attracting and retaining highly qualified clinical operations professionals.
Associate Director, Clinical Regulatory Denali TherapeuticsAssociate Director, Clinical RegulatorySouth San Francisco, CA$171,000–$223,000 / yearDevelops, manages, and mentors junior regulatory professionals and contributes to creating a culture regulatory innovation and excellence; leads direct report(s), if applicable, through annual goal setting, growth planning, adherence to company policies, maintains training compliance and provides ongoing feedback on growth, development and areas of improvement. Key Accountabilities/Core Job Responsibilities: Accountable for developing regulatory strategy for complex development programs; leads project teams in implementing and delivering the regulatory strategy across multiple programs/indications and/or programs of increasing complexity.
Director, Clinical Regulatory Denali Therapeutics IncDirector, Clinical RegulatorySouth San Francisco, CA$211,000–$258,667 / yearKey Accountabilities/Core Job Responsibilities: • Developing and implementing regulatory strategy for complex development programs, leading project teams in implementing and delivering the regulatory strategy across multiple programs/indications and/or programs of increasing complexity • Participating in cross-functional teams to provide regulatory feedback and support, proactively assessing and communicating potential risks and mitigation opportunities • Overseeing and directly leading global Health Authority interactions, independently executing preparation, submission, and maintenance of regulatory applications, including initial applications, routine amendments, annual reports, IND safety reports, and correspondence with global Health Authorities • Partnering with external vendors in support of regulatory document preparation and submission • Leading and executing non-project regulatory activities • Maintaining up-to-date knowledge of the regulatory landscape, regulations, and guidelines and for developing thoughtful, data-driven strategies for influencing the regulatory landscape • Complying with relevant governing laws, regulations, guidelines, and Denali SOPs • Recruiting, developing, managing, and mentoring regulatory professionals; contributing to creating a culture of regulatory innovation and excellence; leading direct report(s), if applicable, through annual goal setting, growth planning, adherence to company policies, training compliance and for providing ongoing feedback on growth, development and areas of improvement. The Director, Clinical Regulatory, is accountable for leading and overseeing global Health Authority interactions, project team support, regulatory intelligence activities, and proposing and implementing department initiatives in our drive to defeat neurodegeneration.
Associate Director, Clinical Regulatory Denali Therapeutics IncAssociate Director, Clinical RegulatorySouth San Francisco, CA$215,544–$260,822 / yearKey Accountabilities/Core Job Responsibilities: • Accountable for developing regulatory strategy for complex development programs; leads project teams in implementing and delivering the regulatory strategy across multiple programs/indications and/or programs of increasing complexity • Responsible for identifying regulatory risk and mitigation in support of development plans • Accountable for overseeing and directly leading global Health Authority interactions • Independently executes preparation, submission, and maintenance of regulatory applications, including initial applications, routine amendments, annual reports, IND safety reports, and correspondence with global Health Authorities • Participates in cross-functional teams, providing regulatory feedback and support • Partners with external vendors in support of regulatory document preparation and submission • Maintains up-to-date knowledge of the regulatory landscape, regulations, and guidelines • Identifies and maintains leadership/ownership of non-project activities • Complies with relevant governing laws, regulations, guidelines, and Denali SOPs • Develops, manages, and mentors junior regulatory professionals and contributes to creating a culture regulatory innovation and excellence; leads direct report(s), if applicable, through annual goal setting, growth planning, adherence to company policies, maintains training compliance and provides ongoing feedback on growth, development and areas of improvement. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
Senior Clinical Development Medical Director Exelixis IncSenior Clinical Development Medical DirectorSan Francisco, CA$283,000–$402,000 / yearSUMMARY/JOB PURPOSE: In collaboration with the Exelixis clinical teams, the primary role is to lead and execute early/late stage clinical trials for oncology products in development. EDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS: Education/Experience: MD (board certification or eligibility in Oncology or Hematology/Oncology desirable but not essential) required with a minimum of 8 years of post-residency experience.
Senior Director, Clinical Development BridgeBio Pharma, Inc.Senior Director, Clinical DevelopmentSan Francisco, CA$340,000–$375,000 / yearThe final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. Skill Development & Career Paths: People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility.
Director Clinical Pharmacology & DMPK Alumis IncDirector Clinical Pharmacology & DMPKSouth San Francisco, CA$200,000–$240,000 / yearAlumis is seeking a Director of Clinical Pharmacology & DMPK to drive clinical pharmacology strategy and PK/PD modeling for our small-molecule programs in immune-mediated diseases. Specific responsibilities include but are not limited to: Lead clinical pharmacology strategy, dose selection, and PK/PD and biomarker planning across early and late-stage programs.
Senior Manager/Director Clinical Operations Lycia Therapeutics IncSenior Manager/Director Clinical OperationsSouth San Francisco, CARemote$180,000–$198,000 / yearAbility to manage in a consensus environment through teamwork, trust and shared expectations, influencing strategic direction of complex global clinical operations issues, solicit information, listen well, persuade others, make important decisions and shape outcomes. Build, develop and train internal staff and external vendors, structure department for enhancing efficiency, and create a highly engaged work environment for attracting and retaining highly qualified clinical operations professionals.
NewMedical Director, Clinical Development(Nephrology) Jade BiosciencesMedical Director, Clinical Development(Nephrology)San Francisco, CaliforniaRemote$270,000–$300,000 / yearEducate and advise clinical sites/investigators to support enrollment and optimal study conduct, including presenting at investigator meetings and/or site initiation visits, and serving as the medical point of contact for site staff questions about patient eligibility, and providing input into patient safety assessment and management. Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases.
Director, Clinical Compliance Jade BiosciencesDirector, Clinical ComplianceSan Francisco, CaliforniaRemoteEmbedded within the Development Operations Operational Excellence team, this role functions as an internal GCP compliance leader who partners closely with study teams, vendors, and Quality Assurance (QA) to maintain inspection readiness and operational quality across all clinical programs. Support study teams in identifying and appropriately escalating significant compliance issues, protocol deviations, and site noncompliance, ensuring issues are investigated, documented, and resolved in accordance with regulatory expectations.
Director Clinical Pharmacology & Dmpk Alumis Inc.Director Clinical Pharmacology & DmpkSouth San Francisco, CA$200,000–$240,000 / yearAlumis is seeking a Director of Clinical Pharmacology & DMPK to drive clinical pharmacology strategy and PK/PD modeling for our small-molecule programs in immune-mediated diseases. Specific responsibilities include but are not limited to: Lead clinical pharmacology strategy, dose selection, and PK/PD and biomarker planning across early and late-stage programs.
Director, Clinical Business Development Syneos - Commercial - ProdDirector, Clinical Business DevelopmentSan Francisco, CA$174,734–$309,733 / yearBy developing tailored engagement plans, building trusted relationships, and orchestrating multi-functional solution development, the Director, Regional BD drives both immediate impact and develops long-term value. Collaborates closely with cross-functional teams—including operations, therapeutic strategy, deal strategy, and delivery —to co-develop solutions that address client-specific challenges.
Senior Director, Clinical Development BridgeBio Pharma IncSenior Director, Clinical DevelopmentSan Francisco, CA$340,000–$375,000 / yearThe final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. Skill Development & Career Paths: People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility.
Associate Director, Clinical Data Management Structure Therapeutics IncAssociate Director, Clinical Data ManagementSouth San Francisco, CA$180,000–$220,000 / yearThe companys platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. The AD serves as primary DM contact to collaborate closely with cross-functional teams, including Clinical Operations, Biostatistics, Clinical Development and Regulatory Affairs, to ensure that data management activities align with the overall clinical development strategy and regulatory requirements.
Senior Director, Clinical Operations Compliance Management (Gcp/Biotechnology/Oncology) Exelixis Inc.Senior Director, Clinical Operations Compliance Management (Gcp/Biotechnology/Oncology)Alameda, CA$246,000–$349,500 / yearThe Senior Director of COCM is a key partner with our Quality Assurance team and other functional groups (including Clinical Development, Data Management, etc.) and is responsible for supporting inspection readiness activities, driving cross-study consistency in study execution and compliance with governing functional procedures and processes, and escalation of identified operational issues within development and of identified quality issues to QA. EDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS: Education: Bachelor's degree in related discipline and a minimum of 15 years of related experience; or, Master's degree in related discipline and a minimum of 13 years of related experience; or, Doctoral degree in related discipline and a minimum of 12 years of related experience; or, Equivalent combination of education and experience.
Director of Quality Assurance, Clinical Caribou Biosciences, Inc.Director of Quality Assurance, ClinicalBerkeley, CA$220,000–$235,000 / yearProvide Clinical Quality Assurance (GCP) strategic and technical leadership and Subject Matter Expertise (SME) to clinical study teams; Partner with the teams to effect appropriate and timely documentation of quality event management, including CAPA plans in support of product pipeline. The successful candidate must have the ability to execute QA tasks independently; effectively represent QA in a GCP, PV, and GLP focused team settings and manage quality related activities related to clinical vendors, investigator sites and regulatory agencies.
Associate Director, Clinical Supply Planning Cytokinetics IncAssociate Director, Clinical Supply PlanningSouth San Francisco, CA$195,390–$227,955 / yearThe Associate Director, Clinical Supply Chain, will develop and formulate supply chain strategies, meet project deliverables, solve business problems and drive improvements within Global Clinical Supply Chain (GCSC), as well as the Cytokinetics enterprise. Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.
Senior Director, Clinical Development Annexon, Inc.Senior Director, Clinical DevelopmentSan Francisco, CARemote$336,000–$374,000 / yearOur novel scientific approach targets upstream C1q to block the classical complement inflammatory cascade before it starts, and its therapeutic candidates are designed to provide meaningful benefits across multiple autoimmune, neurodegenerative and ophthalmic diseases. With proof-of concept data in Guillain-Barré syndrome, Huntington's disease and geographic atrophy, we are rigorously advancing our mid-to late-stage clinical trials to bring new potential treatments to patients as quickly as possible.
Senior Director, Clinical Research-Infectious Disease Vir Biotechnology, Inc.Senior Director, Clinical Research-Infectious DiseaseSan Francisco, CA$235,500–$329,500 / yearVir Biotechnology is looking for a Senior Director, Clinical Research-Infectious Disease to facilitate late‑stage clinical development for our hepatitis delta (HDV) portfolio, with a primary focus on activities supporting the Phase III clinical program and health authority submission activities. Reporting to the VP, Clinical Research, this senior leader will serve as the key clinical voice in shaping and executing the clinical development strategy You will concentrate on advancing our HDV assets through global Phase III,BLA‑enabling activities and support on relevant commercial activities.
Associate Director, Clinical Transactional Counsel Vir Biotechnology, Inc.Associate Director, Clinical Transactional CounselSan Francisco, CA$167,500–$246,500 / yearDirect negotiation, and oversight of negotiations, of clinical study agreements (including clinical trial agreements, confidentiality agreements and related contracts) and clinical vendors agreements (including master service agreements, MTAs and SOWs) in accordance with established development timelines. Review established country specific templates for clinical trial agreements, confidentiality agreements, master service agreements, consulting agreements and other development agreements to ensure compliance with country regulations, align with business practices, market competitiveness and incorporate lessons learned.
Director, Clinical Scientists Denali TherapeuticsDirector, Clinical ScientistsSouth San Francisco, CA$272,000–$336,000 / yearKey Accountabilities / Core Job Responsibilities: Lead clinical team in new therapeutic areas or highly complex projects including the development of multiple, complex clinical protocols, informed consents, and other study materials. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
Director, Clinical Scientists Denali Therapeutics IncDirector, Clinical ScientistsSouth San Francisco, CA$272,000–$336,000 / yearKey Accountabilities / Core Job Responsibilities: Lead clinical team in new therapeutic areas or highly complex projects including the development of multiple, complex clinical protocols, informed consents, and other study materials. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
NewDirector, Clinical Business Development Syneos Health IncDirector, Clinical Business DevelopmentSan Francisco, CATogether we share insights, use the latest technologies and apply advanced business practices to speed our customers' delivery of important therapies to patients. Selecting us as an employer secures a career in which you're guaranteed to: Collaborate with passionate problem solvers Partner with the most diverse team of experts in the industry.
Associate Director, Clinical Supply Chain Olema Pharmaceuticals IncAssociate Director, Clinical Supply ChainSan Francisco, CA$185,000–$200,000 / yearYour work will primarily encompass: • End to End clinical supply chain management • Develop and implement global Clinical Supply Chain strategies • Manage global inventories, shipping, and third-party manufacturers/logistics providers • Develop and manage Interactive Response Technologies (IRT) systems • Oversight packaging, labeling, and distribution activities at multiple vendors • Generate and manage clinical labels • Identify supply chain risks, escalate if needed, and close out risk items • Partner with Clinical Operations to align on assumptions and build clinical supply to meet program demand • Represent Clinical Supply Chain on study execution teams. As the Associate Director of Clinical Supply Chain reporting to the Senior Director, Clinical Supply Chain, you will plan, create, implement, build, and optimize the clinical supply chain to ensure uninterrupted and timely clinical drug supply for Olema's clinical programs.
Senior Manager/Associate Director, Clinical Fp&A BridgeBio Pharma, Inc.Senior Manager/Associate Director, Clinical Fp&ASan Francisco, CA$165,000–$217,000 / yearClinical Study Financial Intelligence: Analyze clinical trial expense variances against study operational metrics (e.g., enrollment rates, site activations, protocol amendments, vendor activity) to determine whether variances are temporary in nature or reflect permanent, structural changes to the cost profile of a study. Partner with Clinical Operations study managers to understand study plan pivots, enrollment challenges, vendor performance issues, and other factors driving financial deviations; synthesize this context into clear assessments for the Director and senior leadership.
Senior Director, Clinical Operations BigHat Biosciences IncSenior Director, Clinical OperationsSan Mateo, CAClinical Document Generation: Manage the preparation and lifecycle of key clinical documents, including protocols, informed consent forms, investigator brochures, clinical study reports, and regulatory submissions, ensuring accuracy, timeliness, and compliance with applicable guidelines. Translational Biomarker Support: Partner closely with the Translational Biomarker team to ensure clinical operations infrastructure supports biomarker sample collection, handling, and logistics across all trial sites.
Director, Clinical Study Management Eikon Therapeutics, Inc.Director, Clinical Study ManagementMillbrae, CA$226,000–$273,000 / yearThis role will require a minimum of 3 days a week of onsite presence (or more as business needs require) in either of our Jersey City, New Jersey or Millbrae, California offices to ensure effective management and high-performance delivery of clinical studies. The Director will manage all aspects of clinical operations study management for assigned Eikon clinical studies, and be responsible for exquisite inhouse execution of all such clinical trials and oversight of requisite clinical vendors.
Director, Clinical Quality Assurance - Contractor Alumis Inc.Director, Clinical Quality Assurance - ContractorSouth San Francisco, CA$193,000–$242,000 / yearThe Clinical QA Director is responsible to ensure quality is embedded throughout the lifecycle of all the ongoing clinical programs through oversight, assessment and monitoring, risk assessment tools, auditing and risk mitigations. This involves working closely with Clinical Operations, Clinical Development, Clinical Supply Chain, Data Management, Pharmacovigilance, Medical Affairs, Regulatory, Legal, and other teams across Alumis.
Senior Director, Clinical Science Ideaya Biosciences IncSenior Director, Clinical ScienceSouth San Francisco, CA$276,000–$341,000 / yearIn addition to study level activities, the Director/Senior Director will participate in program level activities including authoring/reviewing safety and efficacy summaries, clinical overviews, investigator brochures, risk management plans, periodic safety updates and clinical sections of product labels. Non-Solicitation Policy and Notice to Agencies and Recruiters: IDEAYA's Non-Solicitation Policy strictly prohibits agencies and recruiters from any contact and communication with IDEAYA employees, managers, and leaders to submit unsolicited candidate resumes and/or to solicit business partnerships.
Director, Clinical FP&A BridgeBio Pharma IncDirector, Clinical FP&ASan Francisco, CA$165,000–$217,000 / yearClinical Study Financial Intelligence: Analyze clinical trial expense variances against study operational metrics (e.g., enrollment rates, site activations, protocol amendments, vendor activity) to determine whether variances are temporary in nature or reflect permanent, structural changes to the cost profile of a study. Partner with Clinical Operations study managers to understand study plan pivots, enrollment challenges, vendor performance issues, and other factors driving financial deviations; synthesize this context into clear assessments for the Director and senior leadership.
Associate Director, Clinical Development Mirum Pharmaceuticals IncAssociate Director, Clinical DevelopmentFoster City, CAThe Associate Director, Clinical Development will be responsible for supporting clinical trial related activities for Brelovitug, a key asset in Phase 3, on a cross-functional team of internal and external experts, investigators and government agencies. Activities include but are not limited to drafting key clinical trial and program-level documents, protocol development, support study startup, recruitment, ongoing clinical development management, and closeout as appropriate.
NewSr. Director, Clinical Data Management ALX Oncology Holdings IncSr. Director, Clinical Data ManagementSouth San Francisco, CA$240,000–$280,000 / yearApproximately 12+ years of progressive Clinical Data Management experience within biotechnology, pharmaceutical, or CRO environments, including Phase I-III clinical studies, with demonstrated success leading outsourced Clinical Data Management activities, partnering across functions, and delivering high-quality clinical trial data. As the senior data management leader in a lean biotechnology environment, this individual is responsible for establishing a scalable, fit-for-purpose function that delivers high-quality clinical trial data to support development milestones, regulatory submissions, and future portfolio growth.
Medical Director, Clinical Informatics, Surgical Specialties Sutter HealthMedical Director, Clinical Informatics, Surgical SpecialtiesSan Francisco, CARecognized ability to energize, mobilize, influence, and build accountability with a broad range of stakeholders through effective communication of vision, and the fostering of productive and supportive working relationships with internal and external constituencies. Working knowledge of the clinical care information systems implementation process, integration of workflows, use and support methodologies, regulatory requirements, strategic and tactical planning, project leadership/management and group dynamics.
Medical Director, Clinical Informatics, Behavioral Health Sutter HealthMedical Director, Clinical Informatics, Behavioral HealthSan Francisco, CARecognized ability to energize, mobilize, influence, and build accountability with a broad range of stakeholders through effective communication of vision, and the fostering of productive and supportive working relationships with internal and external constituencies. Working knowledge of the clinical care information systems implementation process, integration of workflows, use and support methodologies, regulatory requirements, strategic and tactical planning, project leadership/management and group dynamics.
Senior Director, Pharmacy Clinical Quality & Safety Sutter HealthSenior Director, Pharmacy Clinical Quality & SafetyEmeryville, CA$242,070.40–$387,316.80 / yearTotal compensation considers multiple factors, including, but not limited to a candidate's experience, education, skills, licensure, certifications, departmental equity, training, and organizational needs. Oversees the assessment, development, implementation, and evaluation of policies, procedures, and programs aimed at ensuring safe, evidence-based pharmacologic care across all healthcare settings.
Medical Director, Clinical Informatics, Anesthesia Sutter HealthMedical Director, Clinical Informatics, AnesthesiaSan Francisco, CARecognized ability to energize, mobilize, influence, and build accountability with a broad range of stakeholders through effective communication of vision, and the fostering of productive and supportive working relationships with internal and external constituencies. Working knowledge of the clinical care information systems implementation process, integration of workflows, use and support methodologies, regulatory requirements, strategic and tactical planning, project leadership/management and group dynamics.
Clinical Development Medical Director (Oncology/Biotechnology) Exelixis Inc.Clinical Development Medical Director (Oncology/Biotechnology)Alameda, CA$254,500–$361,000 / yearEDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS: Education/Experience: MD (board certification or eligibility in Oncology or Hematology/Oncology desirable but not essential) required with a minimum of 5 years of post-residency experience. SUMMARY/JOB PURPOSE: In collaboration with the Exelixis clinical teams, the primary role is to lead and execute clinical trials for oncology products in development.
Associate Director, Clinical Trial Management Annexon IncAssociate Director, Clinical Trial ManagementSan Francisco, CARemote$179,000–$200,000 / yearOur novel scientific approach targets upstream C1q to block the classical complement inflammatory cascade before it starts, and its therapeutic candidates are designed to provide meaningful benefits across multiple autoimmune, neurodegenerative and ophthalmic diseases. With proof-of concept data in Guillain-Barré syndrome, Huntington's disease and geographic atrophy, we are rigorously advancing our mid-to late-stage clinical trials to bring new potential treatments to patients as quickly as possible.
Senior/Executive Medical Director, Clinical Development New Indications Alumis IncSenior/Executive Medical Director, Clinical Development New IndicationsSouth San Francisco, CA$300,000–$400,000 / yearAlumis is seeking an experienced Executive Medical Director or Senior Medical Director to lead clinical development strategy and execution for Phase 1 and Phase 2 studies evaluating envudeucitinib and A-005 across new indications identified for expansion of the Alumis pipeline. This high-impact role will be instrumental in shaping the company's clinical development portfolio, from indication selection through proof-of-concept studies, and will serve as a key scientific leader interfacing with internal teams, regulatory authorities, and the external medical community.
Sr. Director, Clinical Data Management ALX Oncology Inc.Sr. Director, Clinical Data ManagementSouth San Francisco, CA$240,000Approximately 12+ years of progressive Clinical Data Management experience within biotechnology, pharmaceutical, or CRO environments, including Phase I-III clinical studies, with demonstrated success leading outsourced Clinical Data Management activities, partnering across functions, and delivering high-quality clinical trial data. As the senior data management leader in a lean biotechnology environment, this individual is responsible for establishing a scalable, fit-for-purpose function that delivers high-quality clinical trial data to support development milestones, regulatory submissions, and future portfolio growth.
Director, Quality (Clinical) Braveheart BioDirector, Quality (Clinical)San Francisco, CaliforniaThe Director of Quality will serve as a senior quality leader for Braveheart Bio and will be responsible for clinical quality oversight, clinical data integrity, GCP inspection readiness, and support of nonclinical quality activities as needed for our late-stage clinical program in hypertrophic cardiomyopathy (HCM). This leader will partner closely with Clinical Development, Regulatory, Biometrics, PV, Data Management, Medical, Legal and external CRO and vendor partners to ensure effective, inspection-ready clinical quality oversight across all programs.
Executive Director, Clinical Quality Assurance Jade BiosciencesExecutive Director, Clinical Quality AssuranceSan Francisco, CaliforniaRemote$265,000–$300,000 / yearThe Executive Director, Clinical Quality Assurance will perform day-to-day clinical quality operations and compliance activities to support the success of our clinical programs in addition to being a strategic partner to Clinical Development and Operations. Jade’s pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development.
NewDirector, Clinical Operations Jade BiosciencesDirector, Clinical OperationsSan Francisco, CaliforniaRemote$215,000–$240,000 / yearDirects the selection of CROs and other vendors (IxRS, Central Lab, ancillary/tech vendors), directs development of vendor Scopes of Work (SOW), scope changes, budgets, and vendor payments and partners with CROs and other vendors to deliver on study execution. The Director, Clinical Operations will oversee the strategic and operational execution of clinical trials, leading cross-functional teams and collaborating with internal stakeholders and external vendors.
Senior Director, Clinical Operations Pliant Therapeutics, Inc.Senior Director, Clinical OperationsSouth San Francisco, CA$289,000–$320,000 / yearWe believe our platform may be broadly applicable across multiple disease areas including delivery of drug payloads to cells utilizing integrin receptor-binding molecules as tissue-specific delivery and internalization mechanisms. Currently, Pliant is conducting a Phase 1 study of PLN-101095, a small molecule, dual-selective inhibitor of vß8 and vß1 integrins, that has shown encouraging clinical activity in the development of a treatment of immune checkpoint resistant solid tumors.
Medical Director, Clinical Development - Oncology Lyell Immunopharma, Inc.Medical Director, Clinical Development - OncologySouth San Francisco, CA$240,000–$300,000 / yearThis individual contributor role is responsible for providing medical and scientific leadership across one or more clinical trials, supporting protocol development, regulatory interactions, and data interpretation as Lyell advances toward its first approval and commercial launch. At Lyell, we believe that highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other.
Senior/Executive Medical Director, Clinical Development (New Indications) Alumis Inc.Senior/Executive Medical Director, Clinical Development (New Indications)South San Francisco, CA$300,000–$400,000 / yearThis high-impact role will shape Alumis's expanding clinical portfolio from the ground up, from indication selection and study design through proof-of-concept readout, and will serve as a key scientific leader and external face of the program with investigators, regulatory authorities, and the broader medical community. Experience across multiple therapeutic indications, including neurological diseases (e.g., neurodegenerative diseases, movement disorders) and/or inflammatory conditions such as psoriasis, psoriatic arthritis, lupus, or atopic dermatitis.