Principal Scientist, Pharmacokinetics Merck & Co IncPrincipal Scientist, PharmacokineticsWest Point, PA$173,200–$272,600 / yearRequired Skills: ADME, Bioanalytical Method Development, Biopharmaceuticals, Biopharmaceutics, Business Interactions, Clinical Development, Clinical Judgment, Cross-Functional Teamwork, Detail-Oriented, Drug Development, Drug Interactions, Drug Metabolism, Immunoassays, Innovation, Life Science, Mentoring Staff, Pharmacodynamics, Pharmacokinetics, Pharmacology, PKPD Modeling. Demonstrated ability to support early to late stage clinical development programs as a DMPK representative including evaluating and mitigating risks, integrating emerging data into ongoing programs, and clearly communicating with a varied development team.
Principal Sales Engineer, SLED - East Zscaler IncPrincipal Sales Engineer, SLED - EastPARemote$175,875–$251,250 / yearThe range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations and could be higher or lower based on a multitude of factors, including job-related skills, experience, and relevant education or training. Demonstrated ability to act as a Consultative AI Advisor, guiding customers through AI change management, including mapping manual business workflows to agentic AI systems and managing expectations around non-deterministic outputs.
Principal Technical Program Manager JPMorgan Chase & CoPrincipal Technical Program ManagerWilmington, DEAs a Principal Technical Program Manager Model & Analytics in Corporate Sector, you will lead complex, multi-functional technology projects and programs that will impact experiences for multiple groups across the firm, including clients, employees, and stakeholders. Lead end-to-end execution of complex technology programs across multiple workstreams, managing scope, timelines, dependencies, resources, and budgets while addressing roadblocks and risks.
Principal Specialist Sales Engineer, Zero Trust Branch - Healthcare Zscaler IncPrincipal Specialist Sales Engineer, Zero Trust Branch - HealthcarePARemote$175,875–$251,250 / yearThe Speciality Sales team is a global group of professionals who are passionate about delighting our customers, nurturing trusted partnerships, and sharing their expertise to drive a secure, cloud-enabled digital future and further cement our position as the world leader in cloud security. Sales, Customer Success, Sales Enablement, Solution Architects, Business Development, Transformation, and Technology Partnerships all work together to demonstrate the power and agility of Zscaler cloud transformation to the world, and we are looking for your expertise to elevate our Exposure Management team.
Principal Software Engineer NFI Industries IncPrincipal Software EngineerTrenton, NJ$106,486–$141,981 / yearHowever, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor's legal duty to furnish information. Experience with Supply Chain modeling platforms like Supply Chain Guru, Llama.ai, NextMV, Gains, Sophus, Starboard, Optilogic, or TMOD.
Principal Scientist Frontage Clinical Services IncPrincipal ScientistExton, PADesign, perform, troubleshoot, and interpret a broad range of in vitro ADME studies including metabolic stability, CYP inhibition, time-dependent inhibition (TDI), CYP induction, reaction phenotyping, enzyme kinetics, plasma protein binding, blood-to-plasma partitioning, tissue binding, using LC-MS/MS-based analytical methods. Our core competencies include pre-clinical, drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.
Principal AI Security Specialist - East Zscaler IncPrincipal AI Security Specialist - EastPARemote$175,875–$251,250 / year10+ Years of Solutions Engineering Mastery: A proven track record in a customer-facing technical role (Sales Engineering, Solutions Architecture, or Technical Advisory) navigating complex, enterprise-level sales cycles. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations and could be higher or lower based on a multitude of factors, including job-related skills, experience, and relevant education or training.
Principal Specialist Sales Engineer, Data Security - Majors, East Zscaler IncPrincipal Specialist Sales Engineer, Data Security - Majors, EastTrenton, NJ$175,875–$251,250 / yearZscaler is committed to providing reasonable support (called accommodations or adjustments) in our recruiting processes for candidates who are differently abled, have long term conditions, mental health conditions or sincerely held religious beliefs, or who are neurodivergent or require pregnancy-related support. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations and could be higher or lower based on a multitude of factors, including job-related skills, experience, and relevant education or training.
Sr Principal Cybersecurity Architect - AI JPMorgan Chase & CoSr Principal Cybersecurity Architect - AIWilmington, DEAs a Senior Principal Cybersecurity Architect at JPMorganChase within the Cybersecurity and Technology Controls - Consumer & Community Banking (CTC CCB) line of business, you provide deep cybersecurity expertise and work across teams to identify, create, and communicate risk, mitigation options, and solutions. Leverage your deep cross-domain expertise to bring together talent that will consistently create AI-enabled solutions, processes, and reusable proof-of-concept models for cybersecurity while remaining at the forefront of best practices for cybersecurity policy and technological advances.
Sr. Principal Scientist (Sr. Director) - Regulatory Liaison Merck & Co IncSr. Principal Scientist (Sr. Director) - Regulatory LiaisonNorth Wales, PA$190,800–$300,300 / yearRequired Skills: Biological Sciences, Clinical Reporting, Drug Development, Global Health, In Vitro Diagnostics (IVD), Multiple Therapeutic Areas, Pharmaceutical Regulatory Affairs, Process Improvements, Product Approvals, Regulatory Affairs Compliance, Regulatory Affairs Management, Regulatory Communications, Regulatory Compliance, Regulatory Issues, Regulatory Strategies, Regulatory Strategy Development, Written Communication. As the Global Regulatory Lead (GRL), the Senior Principal Scientist functions as the regulatory single, accountable, global point of contact on the project team and interacts with the global regulatory agencies and/or subsidiaries with regard to global regulatory strategy/registration requirements for one or more company investigational and marketed drugs/biologics in early- and/or late-stage development.
Principal Enterprise Architect - Remote CSAA Insurance GroupPrincipal Enterprise Architect - RemotePARemote$186,660–$207,400 / yearAlabama - Home Teleworkers, Alabama - Home Teleworkers, Arkansas - Home Teleworkers, California - Home Teleworkers, Colorado - Home Teleworkers, Connecticut - Home Teleworkers, Delaware - Home Teleworker, District of Columbia - Home Teleworkers, Florida - Home Teleworkers, Georgia - Home Teleworkers, Idaho - Home Teleworkers, Illinois - Home Teleworkers, Indiana - Home Teleworkers, Iowa - Home Teleworkers, Kansas - Home Teleworker, Kentucky - Home Teleworkers, Louisiana - Home Teleworkers, Maine Home Teleworkers, Maryland - Home Teleworkers, Massachusetts - Home Teleworkers, Michigan - Home Teleworkers, Minnesota - Home Teleworkers, Mississippi - Home Teleworker, Missouri - Home Teleworker, Montana - Home Teleworkers {+ 21 more}. Experience designing and securing on-premises or hybrid AI infrastructure, including GPU-accelerated compute, private AI/ML platforms, model hosting environments, data pipelines, and supporting network, identity, storage, and workload security controls.
Principal Scientist/Director (Downstream), Biologics Drug Substance Commercialization (BDSC) Merck & Co IncPrincipal Scientist/Director (Downstream), Biologics Drug Substance Commercialization (BDSC)West Point, PA$173,200–$272,600 / yearRequired Skills: Biological Engineering, Biologics, Biopharmaceutical Manufacturing, Bioproduction, Bioproducts, Chemical Engineering, Commercialization, Cross-Functional Teamwork, Decision Making, Downstream Processing, Drug Development, Manufacturing Scale-Up, Process Characterization, Process Development (PD), Process Transfers, Purification Methods, Strategic Thinking, Technology Transfer. The Principal Scientist (Director level) position in BDSC-Downstream team is a senior scientific and people leadership role supporting late stage and commercial biologics programs, with a primary focus on biologics downstream processing.
Principal Scientist, Translational Medicine, Neuroscience Merck & Co IncPrincipal Scientist, Translational Medicine, NeuroscienceWest Point, PA$255,800–$402,700 / yearPrimary responsibilities for the Principal Scientist include the following: Working with basic science teams on specific diseases and therapeutic areas, providing clinical expertise for identification and validation of novel targets, including the design of preclinical and clinical experiments to validate targets and/or pathways, and leveraging this work for development of novel therapeutics. Translational Medicine is specifically responsible for: Contributing to the identification of novel targets by partnering with Discovery Sciences to bring a clinical perspective into the earliest stages of target identification and validation, and to execute clinical studies to evaluate the relevance of potential targets to human disease in order to justify full development.
Principal Scientist, Process Modeling, Digital Insights Merck & Co IncPrincipal Scientist, Process Modeling, Digital InsightsWest Point, PA$173,200–$272,600 / yearThe successful candidate will play a technical leadership role in establishing engineering simulation as a core capability across DSCS partnering deeply with experimentalists, process engineers, and DS technical leads to translate first-principles model outputs into actionable CMC decisions. In this Principal Scientist role, the successful candidate will apply first-principles engineering, computational fluid dynamics (CFD), and physics-based simulation to bring predictive rigor to scale-up across a multi-modality pipeline from small to large molecules, with a current focus on biologics.
NewPrincipal Product Manager - Personal Loans Growth Upgrade IncPrincipal Product Manager - Personal Loans GrowthWilmington, DE$180,000–$230,000 / yearThe role requires the ability to receive and exchange information with customers, peers, supervisors, and cross-functional partners through available communication channels, which may include meetings, email, phone, and digital collaboration tools, and may involve real-time, verbal, or in-person exchanges depending on business need. Most recently, we were named one of the World's Top Fintech Companies by CNBC, Best Places to Work by Built In, Best Places to Work by the San Francisco Business Times, America's Greatest Workplaces by Newsweek, Best Startup Employer by Forbes, and Healthiest Employers by Phoenix Business Journal.
NewPrincipal Scientist (Director), Clinical Research, Immunology Merck & Co IncPrincipal Scientist (Director), Clinical Research, Immunologyupper gwynedd, PA$255,800–$402,700 / yearWork closely with a cross-functional group of experts in commercialization, regulatory affairs, statistics, and manufacturing to manage clinical development projects; and assist the Senior Director, Associate Vice-President/Vice-President and Product Development Team Lead in ensuring that appropriate corporate personnel is informed of the progress of studies of our company and competitors' drugs and internal and external expert opinion on scientific questions relevant to his/her areas of responsibility. With a focus on late-stage development, the Clinical Director will manage the entire cycle of clinical development, including determination of appropriate disease indications to pursue and subsequent study design, initiation, execution, monitoring, analysis, regulatory filing, and publication.
NewAssociate Principal Scientist, Engineering - Vaccine, Sterile Drug Product Commercialization Merck & Co IncAssociate Principal Scientist, Engineering - Vaccine, Sterile Drug Product CommercializationWest Point, PA$142,400–$224,100 / yearRequired Skills: Biochemistry, Biological Engineering, Biologics, Biopharmaceuticals, Bioprocess Engineering, Bioprocessing, Biotechnology, Chemical Engineering, Commercialization, Decision Making, Drug Product Manufacturing, Manufacturing Scale-Up, Process Improvements, Process Scale Up, Process Transfers, Protein Purifications, Regulatory Submissions, Shop Floor Management, Technical Writing, Technology Transfer, Vaccine Development, Virus Production. As part of Our Company's Manufacturing Division, the Sterile Drug Product Commercialization group provides the technical process leadership and laboratory capabilities for late stage and commercial drug product processes for vaccines, biologics, and sterile pharmaceutical products.
NewPRINCIPAL R&D/PRODUCT DVL ENGINEER TE Connectivity plcPRINCIPAL R&D/PRODUCT DVL ENGINEERMiddletown, DE$154,100–$231,100 / yearAs a Principal Engineer in the Power Integrity Center of Excellence (PI COE), you will lead advanced power integrity (PI) research, modeling, and validation for next-generation high-speed interconnects and chassis deployed in AI data centers and high-performance computing (HPC) environments. In this role, you will explore emerging PI methodologies, conduct in-depth literature reviews, formulate structured research plans, and develop innovative engineering solutions - including in technically ambiguous or undefined problem spaces.
Principal Biostatistician CSL Behring LLCPrincipal BiostatisticianKing of Prussia, PAWe use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives. Focused on serving patients' needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas.
Senior Principal Scientist, Clinical Research, Breast Cancer Merck & Co IncSenior Principal Scientist, Clinical Research, Breast CancerNorth Wales, PA$282,200–$444,200 / yearMonitoring and managing the conduct of ongoing or new clinical trials for investigational or marketed Oncology drugs; Analyzing and summarizing the clinical findings from studies to support decisions regarding safety and efficacy as well as new drug applications, clinical study reports, or publication; and. Assist the Senior/Executive Director in ensuring that appropriate corporate personnel are informed of the progress of studies of our Company's and competitors' drugs and internal and external expert opinion on scientific questions relevant to his/her areas of responsibility.