The Department of Structural Biology at St Jude Children’s Research Hospital is seeking to hire a Director of the Single-Molecule imaging Center (SMC) to lead an interdisciplinary team, whose backgrounds span computer science, engineering, applied math, biophysics and biology, to advance the frontiers of single-molecule research while also implementing focused strategies to work with non-experts seeking to incorporate single-molecule methods into their discovery pipeline. The SMC is integrated into a community of institutionally-funded laboratories and innovation centers at St. Jude, each with their own dedicated staff, including the Cryo-EM Center , the Protein Technology Center , the Cell and Tissue Imaging Center , The Center for Bioimage Informatics , The Center for Applied Bioinformatics , the Center of Excellence for Data-driven Discovery and the Center for Advanced Genome Engineering (CAGE).