Associate Scientist, Oligonucleotide Chemistry & Delivery Denali TherapeuticsAssociate Scientist, Oligonucleotide Chemistry & DeliverySouth San Francisco, CA$106,000–$138,000 / yearSupport high-throughput and mid-scale oligonucleotide synthesis activities, including the evaluation of novel chemistries, modifications, and workflow innovations to enable rapid discovery-stage generation of siRNA/ASOs and bioconjugates within one or more preclinical drug discovery programs. Apply analytical technologies, including UV-Vis spectrophotometry, high-performance liquid chromatography (HPLC), mass spectrometry (MS), multi-angle light scattering (MALS), and other orthogonal characterization techniques, to analyze, purify, quantify, and characterize oligonucleotides and bioconjugates.
Computational Chemistry Expert - PhD MercorComputational Chemistry Expert - PhDSan Francisco, CaliforniaRemote$70–$100 / hourDesign challenging computational problems in Computational Chemistry & Electronic Structure using PySCF for quantum chemistry calculations. Collaborate with AI research teams to ensure problems align with real scientific workflows.
Senior Scientist, Surface Chemistry Ultima GenomicsSenior Scientist, Surface ChemistryFremont, CA$120,000–$140,000 / yearThis role pays between $120,000 and $140,000, if performed in California, and your actual base pay will depend on your skills, qualifications, experience, and location. Experience with vapor-phase and CVD-style deposition of organosilanes, thiols, or related surface chemistries, biomaterials coatings and/or bioconjugation chemistry.
Bioconjugate & Surface-Chemistry Consultant Astera InstituteBioconjugate & Surface-Chemistry ConsultantEmeryville, CaliforniaUnlike traditional non-profit research organizations, projects supported by Astera operate like high-velocity startups, allowing us to focus on ambitious goals, match structure to problem, and attract strong technical talent and leadership. The Astera Institute is seeking a Bioconjugate & Surface-Chemistry Consultant to advise on and develop the surface chemistry that anchors a DNA-origami structure to a device surface with controlled placement and orientation.
Chemistry - Graduates - AI Training - San Francisco, US Prolific Academic LtdChemistry - Graduates - AI Training - San Francisco, USSan Francisco, CAWe're looking for Chemistry Experts and Chemical Engineers to join our Expert Network to help train and evaluate cutting-edge AI models using real-world chemical expertise. We've built a unique platform that connects researchers and companies with a global pool of participants, enabling the collection of high-quality, ethically sourced human behavioural data and feedback.
Scientist, Delivery Sciences Lipid Chemistry NewLimitScientist, Delivery Sciences Lipid ChemistrySouth San Francisco, CA$130,000–$171,000 / yearNewLimit is seeking a Lipid Chemist to design, synthesize, and characterize ionizable lipids, PEG-lipid Conjugates, peptide and antibody conjugates to build our targeting LNP platform with a particular focus on getting nucleic acid payloads into target cells and tissues beyond the liver. Develop conjugation chemistry that links peptides, antibodies, nanobodies, and small-molecule ligands to lipid anchors, generating building blocks for cell- and tissue-selective delivery to support tLNP research and pipeline targets.
Scientist / Senior Scientist, Medicinal Chemistry Capable LabsScientist / Senior Scientist, Medicinal ChemistrySan Francisco, CaliforniaDesign and execute synthetic routes using solid-phase and solution-phase workflows, including functional group transformations, coupling chemistry, protecting group strategies, late-stage diversification, cleavage/deprotection where relevant, purification, and analytical characterization. Troubleshoot synthetic and analytical issues, including failed reactions, low conversion, poor selectivity, low crude purity, side products, solubility limitations, purification challenges, and instrument downtime.
Associate Scientist, Organic Chemistry Capable LabsAssociate Scientist, Organic ChemistrySan Francisco, CaliforniaPurify and characterize compounds using analytical HPLC, prep HPLC, LC-MS, NMR, flash chromatography, SFC, and related methods; record identity, purity, yield, and batch-level QC data before handoff. Run solid-phase and solution-phase synthesis workflows where useful, including resin-based chemistry, coupling/deprotection cycles, cleavage, crude analysis, purification, and final compound QC.
Senior Scientist, Peptide Chemistry (Night Shift) Capable LabsSenior Scientist, Peptide Chemistry (Night Shift)San Francisco, CaliforniaTroubleshoot synthetic and analytical issues during night-shift hours, including failed reactions, low conversion, low crude purity, side products, solubility limitations, cleavage/deprotection issues, purification challenges, and instrument downtime. Prepare compounds for in vitro and in vivo testing, maintain rigorous experimental records, and communicate overnight synthesis results, issues, timelines, and risks clearly to the day team.
Scientist / Senior Scientist, Organic Chemistry Capable LabsScientist / Senior Scientist, Organic ChemistrySan Francisco, CaliforniaDesign and execute synthetic routes using solid-phase and solution-phase workflows, including functional group transformations, coupling chemistry, protecting group strategies, late-stage diversification, cleavage and deprotection where relevant, purification, and analytical characterization. Troubleshoot synthetic and analytical issues with strong experimental judgment, including failed reactions, low conversion, poor selectivity, low crude purity, side products, solubility limitations, purification challenges, poor recovery, and instrument downtime.
Adjunct Professor - Chemistry Lab University of San FranciscoAdjunct Professor - Chemistry LabSan Francisco, CAFor the fall 2026 semester, all courses will begin on Tuesday August 25 and end on Wednesday December 9.There are no classes on the following weeks: Week of August 24 (first week of class). Job Summary: The Department of Chemistry ( https://www.usfca.edu/ ) invites applications to teach undergraduate laboratory courses in the fall 2026 semester.
Analytical Chemistry Scientist Octant BioAnalytical Chemistry ScientistEmeryville, CA$135,000–$155,000 / yearIdentify, develop, and deploy chromatographic and mass spectrometric methodologies - including reversed-phase, HILIC, SFC, and 2D-LC/MS separations - to analyze small molecules to support both our in-house high throughput synthesis capabilities and ADME/PK property characterization. The Navigator is an expanding set of drug discovery and development capabilities with three interwoven components that operate together: Generative Biology- Multiplexed measurements from engineered sensors in human cells to understand cellular mechanisms.
Production Technician - Chemistry EarthOpticsProduction Technician - ChemistryEmeryville, CAOur mission is to be the leading soil information company, delivering maps that growers, farmers, ranchers, and other stakeholders use to cost-effectively increase yields and improve soil health and the climate. Collaborate with cross-functional lab teams (e.g., blending lab, carbon lab) to support overall lab operations and workflow efficiency.
Senior Scientist, Oligonucleotide Design and Chemistry RD PartnersSenior Scientist, Oligonucleotide Design and ChemistrySouth San Francisco, California£130,832–£174,330In-depth knowledge of oligonucleotide/peptide therapeutics, including chemical structure search tools, synthesis techniques, purification instrumentation, and analysis methods for chemically modified oligonucleotides. R&D Partners is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe.
Computational Chemistry / Theory Consultant Astera InstituteComputational Chemistry / Theory ConsultantEmeryville, CaliforniaThe Astera Institute is seeking a Computational Chemistry / Theory Consultant to provide the specialist molecular-simulation and theory for a nanoscale electrostatic actuator — the electrostatics that drive it and the mechanics of its moving parts (charged plate, force transmitter, and amplifying linkage) — and predict the experimental quantities the team measures on the bench. Model electrostatic actuation — how an applied field drives the charged DNA-origami plate through an ionic solution and into a polymer cushion — using appropriate methods (e.g., Poisson–Boltzmann, explicit-ion molecular dynamics, or continuum modeling) to predict the device's voltage–displacement and force behavior.
Scientist / Senior Scientist, Peptide Chemistry Capable LabsScientist / Senior Scientist, Peptide ChemistrySan Francisco, CaliforniaLead and scale end-to-end peptide synthesis workflows, including sequence design, resin loading, coupling/deprotection cycles, cleavage, purification, and analytical characterization. Run microwave-assisted solid-phase peptide synthesis, maintain the synthesizer, and troubleshoot failed couplings, low crude purity, side products, cleavage issues, and instrument downtime.
Associate Scientist, Peptide Chemistry Capable LabsAssociate Scientist, Peptide ChemistrySan Francisco, CaliforniaRun microwave-assisted solid-phase peptide synthesis, support routine synthesizer maintenance, and help troubleshoot failed couplings, low crude purity, side products, cleavage issues, and instrument downtime. Execute end-to-end peptide synthesis workflows, including resin loading, coupling and deprotection cycles, cleavage, purification, analytical characterization, and sample preparation for testing.
26-27 SY Teaching Jobs: Chemistry, Physics Kreyco26-27 SY Teaching Jobs: Chemistry, PhysicsOakley, CATo prepare for these opportunities, we are searching for candidates interested in teaching Chemistry and/or physics for middle and high school level students . Kreyco (formerly known as Language Learning Network) is a nationwide organization that specializes in preK-12 education.
Staff Software Engineer, Machine Learning And Computational Chemistry Eikon Therapeutics, Inc.Staff Software Engineer, Machine Learning And Computational ChemistryMillbrae, CA$200,000–$241,500 / yearAs part of Eikon's diverse team, you will interface with biologists, chemists, microscopists, and optical and automation engineers to design and deploy computational solutions that enable the exploration and quantification of Eikon's high-content datasets. Practical and theoretical understanding of computational chemistry methods including docking, MD (Molecular Dynamics), FEP (Free Energy Perturbation), and retrosynthetic prediction applied to early drug discovery programs.
NewScientist Ii/Senior Scientist, Computational Chemistry, Drug Discovery LILAScientist Ii/Senior Scientist, Computational Chemistry, Drug DiscoverySan Francisco, CA$140,800–$217,800 / yearThis person will bring practical computational chemistry experience in a drug discovery context and will work alongside AI systems to make sure agent-generated optimization plans, compound prioritizations, and modeling workflows are chemically and scientifically sensible. The role spans docking, virtual screening, SAR modeling, molecular property prediction, compound prioritization, medicinal chemistry support, live program support, and, most centrally, the design and supervision of computational chemistry tools for agentic workflows.