Principal Software Engineer - Python Veeva SystemsPrincipal Software Engineer - PythonBoston, MARemote$150,000–$300,000 / yearUnlike a traditional corporation, whose only legal duty is to maximize shareholder value, PBCs consider their public benefit purpose and the interests of those materially affected by the corporation's conduct-including customers, employees, and the community-in addition to shareholders' interests. The team will be AI-first in two meaningful ways: using AI to drive engineering productivity and strong engineering discipline, and building a product that applies AI in genuinely innovative ways to problems that matter.
Associate Principal, Commercial Strategy Trinity Life SciencesAssociate Principal, Commercial StrategyWaltham, MA$156,000–$234,000 / yearTrinity's salary bands account for a wide range of factors that are considered in making compensation decisions including but not limited to skill sets and market demand for skills; level of experience and training; specific qualifications, performance, time in role/company, geographic location, and other business and organizational needs. For more than 30 years, the world's leading pharmaceutical, biotech, and medtech companies have relied on Trinity's foresight, execution, and partnership to deliver confident product launches, decisive market advantage, and measurable patient impact.
Associate Principal- Commercial Strategy Trinity Life SciencesAssociate Principal- Commercial StrategyWaltham, MA$156,000–$234,000 / yearTrinity's salary bands account for a wide range of factors that are considered in making compensation decisions including but not limited to skill sets and market demand for skills; level of experience and training; specific qualifications, performance, time in role/company, geographic location, and other business and organizational needs. For more than 30 years, the world's leading pharmaceutical, biotech, and medtech companies have relied on Trinity's foresight, execution, and partnership to deliver confident product launches, decisive market advantage, and measurable patient impact.
Principal Manufacturing Engineer-Npi TransMedics Group, Inc.Principal Manufacturing Engineer-NpiAndover, MA$147,200–$183,600 / yearJob Description: POSITION SUMMARY: The Principal Engineer - NPI Manufacturing serve as the technical project leader for NPI manufacturing activities, driving the development and commercialization of TransMedics perfusion set and OCS products. To accomplish this mission, we partner closely with transplant stakeholders worldwide and help expand their access to healthy donor organs, while delivering the highest quality technology, service, clinical care and outcomes.
Principal Data Engineer CodaMetrixPrincipal Data EngineerBoston, Massachusetts$175,000–$200,000 / yearThe Data Platform team is responsible for executing the data strategy for the organization, ensuring high-quality external data is ingested into the Lakehouse and realized in powerful insights for internal and external customers, while ensuring ML/AI, BI and customer success teams have the data they need to develop and train their models, build insightful dashboards and design semantic layer. Cross-Functional Enablement & Mentorship - Enable ML, BI, Analytics, DevOps, and customer success and implementation teams with training data pipelines, model-ready datasets, feature store architecture, optimized views, dashboards, Tableau refreshes, infrastructure changes, and tenant onboarding.
Principal Mechanical Engineer, Process Equipment Boston Materials, IncPrincipal Mechanical Engineer, Process EquipmentBillerica, MA$160,000–$190,000 / yearDesign and requisition mechanical machinery and components using CAD (SolidWorks preferred), ensuring design specifications are met, and manage design files, revisions, and workflows within a Product Data Management (PDM) system. 8+ years designing, building, and commissioning custom capital equipment in advanced materials, semiconductor packaging, battery, display, web converting, or other environments where the fidelity of a chemical or materials process must be preserved by the equipment design.
Principal Embedded Software Engineer RISE RoboticsPrincipal Embedded Software EngineerSomerville, MAAs a pivotal member of the RISE Robotics Engineering organization, your contributions will shape the future of our company, spearheading the engineering effort to implement electronic controls of truly massive machines. Collaboration: Work closely with cross-functional teams, including mechanical engineers, electrical engineers, and application specialists, to achieve project goals.
Principal Optical Engineer QuEra ComputingPrincipal Optical EngineerBoston, Massachusetts$151,200–$236,250 / yearThe Hardware Engineering Group at QuEra Computing is seeking strong candidates for a Principal Optical Engineer to serve as a senior individual contributor to the company’s mission of building state-of-the-art, manufacturable, and deployable neutral atom quantum computers. Work with physicists to understand requirements and architect optical systems, sub-systems, modules, and components to support QuEra’s neutral atom computers through the full development lifecycle (R&D, productization, maintenance, and beyond).
Principal Software Engineer, Instrument Simulations Lila SciencesPrincipal Software Engineer, Instrument SimulationsCambridge, Massachusetts$204,000–$270,000 / yearFull-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. LILA combines advanced AI models with proprietary AI Science Factory instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy.
Principal Analyst - Enterprise CX Transformation Forrester Research, Inc.Principal Analyst - Enterprise CX TransformationCambridge, MA$141,000–$229,000 / yearYou'll conduct visionary original research that helps senior CX executives across industries build the experiences and CX programs of the future - and you'll advise these leaders on how to customize and implement your findings. In this role, you'll examine how senior CX leaders build and operate cutting-edge CX programs and drive enterprisewide customer-led innovation amid the rise of AI and volatility.
Senior/Principal Scientist, Small Molecule Therapeutics Lila SciencesSenior/Principal Scientist, Small Molecule TherapeuticsCambridge, Massachusetts$148,000–$208,000 / yearFull-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. Automation-forward mindset: experience operating in automation- and robotics-enabled labs, including liquid handling integration, assay automation, and designing scalable, reproducible experimental workflows.
Principal Technical Program Manager, App Lila SciencesPrincipal Technical Program Manager, AppCambridge, Massachusetts$204,000–$270,000 / yearFull-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. LILA combines advanced AI models with proprietary AI Science Factory instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy.
Principal Engineer, Geostructural - Mi-Tech Services, Inc. Michels CorporationPrincipal Engineer, Geostructural - Mi-Tech Services, Inc.Boston, Massachusetts$138,000–$207,000 / yearA Principal Engineer is a leadership role that focuses on overseeing and driving the technical direction of projects for specific geographical regions or scopes of engineering services. Currently holding a Structural Engineer (SE) license or having passed the NCEES 16-hour structural engineering exam with which to obtain an SE license via comity without additional testing needed.
Principal Software Engineer, Berxi Vets HiredPrincipal Software Engineer, BerxiBoston, MassachusettsWe are seeking a highly skilled Principal Software Engineer to lead the design and delivery of scalable, cloud-native digital platform solutions in a direct-to-customer environment. This role plays a key part in shaping technical strategy, mentoring engineering teams, and building secure, high-performance applications that drive business growth.
Principal Performance Test Engineer BlockHiresPrincipal Performance Test EngineerBoston, MassachusettsWe are uniquely positioned at the center of global trading activity, processing over 100 million financial transactions every day, pioneering industry-wide, post-trade solutions and maintaining multiple data and operating centers worldwide. This highly technical position is responsible for the performance engineering of DTCC distributed computing environments and providing analytical stress evaluations of applications/systems and service level compliance using statistical, analytical, and simulation methods.
Principal Manufacturing Engineer Avenue Technologies CompanyPrincipal Manufacturing EngineerTewksbury, MassachusettsAvenue Technologies is seeking a Principal Manufacturing Engineer to support technical, engineering, and program teams in a hands-on environment. Lead or support root cause, corrective action, and continuous improvement activities using data-driven methods.
Principal System Safety Engineer Avenue Technologies CompanyPrincipal System Safety EngineerWoburn, MassachusettsAvenue Technologies is seeking a Principal System Safety Engineer to support technical, engineering, and program teams in a hands-on environment. Coordinate across engineering, program, and customer-facing teams to identify hazards and define effective controls.
Principal Cybersecurity / Threat Hunter Analyst Vets HiredPrincipal Cybersecurity / Threat Hunter AnalystBoston, MassachusettsThis role is ideal for a technical cybersecurity leader passionate about proactively identifying adversaries, strengthening threat detection, and driving rapid, intelligent incident response. The successful candidate will collaborate closely with security engineers and analysts to enhance cyber defense strategies, elevate security maturity, and protect enterprise systems from evolving threats.
Principal Software Engineer Vets HiredPrincipal Software EngineerBoston, MassachusettsThe ideal candidate brings deep technical expertise, strong leadership, and a hands-on approach to building high-impact systems in a fast-paced, collaborative environment. This role plays a critical part in shaping technology strategy, driving architectural excellence, and mentoring engineering teams to support evolving business platforms.
Principal Clinical Trial Manager TransMedics Group, Inc.Principal Clinical Trial ManagerAndover, MA$137,100–$193,700 / yearThis position is responsible for, but not limited to, the following: Leading the process of pre and post market clinical trials for FDA by employing effective organizational strategies and reviewing and presenting the results using rigorous clinical procedures. Experience in medical device (strongly preferred), Outstanding track record leading large complex global clinical trials for medical device products in different phases of the product cycle.