Principal Scientist, Computational Protein Design ModernaTXPrincipal Scientist, Computational Protein DesignCambridge, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. This individual will work in close partnership with structural biology, directed evolution, immunology, translational science, and program teams to advance platform innovation and therapeutic programs across Moderna’s Research and Early Development portfolio.
NewSenior Scientist, Cellular Genomics Pfizer IncSenior Scientist, Cellular GenomicsCambridge, MA$93,600–$156,000 / yearThe role will also include targeted wet-lab genomic contributions, including study design input, sample-processing strategy, assay-quality review, and limited hands-on support for single-cell, sequencing, or spatial workflows when needed to ensure data quality and interpretability. The candidate should be able to connect disease biology, perturbational responses, pharmacology, and translational context into mechanistic interpretations of drug-candidate effects in collaboration with project scientists, wet-lab genomics experts, translational teams, and computational biology partners.
Senior Scientist, Computational Biotherapeutics Engineering PfizerSenior Scientist, Computational Biotherapeutics EngineeringMassachusettsPhD in biochemistry, computational chemistry, computational biology, machine learning, or a related field with 0 t 3 years of experience OR Master's Degree in biochemistry, computational chemistry, computational biology, machine learning with 7 to 8 years of experience OR BA/BS with 9 to 11 years of experience. Implement advanced cutting-edge AI and machine learning workflows for computational protein design (including fine-tuning protein language models and generative protein design) in HPC or scalable cloud computing environments.
Executive Director, Data & Methods (Data and Computational Sciences) Vertex PharmaceuticalsExecutive Director, Data & Methods (Data and Computational Sciences)Boston, Massachusetts$270,600–$406,000 / yearThis leader will set AI and computational strategy that spans the full breadth of modern drug discovery and scientific therapeutic development; and will translate vision into scalable platforms, methods, and tools that serve every modality and measurably speed up discovery and translation, through the development of cutting-edge methods that leverage critical proprietary and public data to drive impact across our global research portfolio. Lead a multidisciplinary organization of scientists, engineers, and managers — building structure, growing other leaders, and driving organizational effectiveness as a leader of leaders.
Executive Director, Data & Methods (Data And Computational Sciences) Vertex Pharmaceuticals, IncExecutive Director, Data & Methods (Data And Computational Sciences)Boston, MA$270,600–$406,000 / yearThis leader will set AI and computational strategy that spans the full breadth of modern drug discovery and scientific therapeutic development; and will translate vision into scalable platforms, methods, and tools that serve every modality and measurably speed up discovery and translation, through the development of cutting-edge methods that leverage critical proprietary and public data to drive impact across our global research portfolio. Lead a multidisciplinary organization of scientists, engineers, and managers - building structure, growing other leaders, and driving organizational effectiveness as a leader of leaders.
Microbiome Computational Scientist Brigham and Women's HospitalMicrobiome Computational ScientistBoston, MA$93,953.60–$136,739.20 / yearWith recent funding from the Massachusetts Life Sciences Center, the Lab has built a state-of-the-art compute cluster with extensive GPU and CPU nodes, with the objective of making advanced deep learning technologies broadly available to microbiome researchers. Applications will include forecasting microbial population dynamics in the gut, characterizing the impact of spatial structure of the microbiome, predicting impact of the microbiome on host phenotype, tracking infections in human populations, elucidating microbial metabolism, and discovering functions of uncharacterized microbial metabolites and proteins.
Microbiome Computational Scientist Mass General BrighamMicrobiome Computational ScientistBoston, MassachusettsWith recent funding from the Massachusetts Life Sciences Center, the Lab has built a state-of-the-art compute cluster with extensive GPU and CPU nodes, with the objective of making advanced deep learning technologies broadly available to microbiome researchers. Applications will include forecasting microbial population dynamics in the gut, characterizing the impact of spatial structure of the microbiome, predicting impact of the microbiome on host phenotype, tracking infections in human populations, elucidating microbial metabolism, and discovering functions of uncharacterized microbial metabolites and proteins.
Principal Scientist, Antibody Discovery and Engineering ModernaTXPrincipal Scientist, Antibody Discovery and EngineeringCambridge, MassachusettsThis individual will operate with a high degree of independence, scientific judgment, and cross-functional influence while partnering with antigen design, structural and computational biology, Immuno-oncology and Autoimmune Therapeutics research leadership, project teams, and external CRO partners. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Computational Scientist, Assay Development Manifold BioComputational Scientist, Assay DevelopmentBoston, MA$118,000–$138,000 / yearManifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems. Using proprietary molecular barcoding technology, we screen hundreds of thousands of protein designs simultaneously in living systems, producing in vivo-validated datasets at a scale no one else can match.
Advanced Process Analytics Scientist Integrated Resources, IncAdvanced Process Analytics ScientistCambridge, MassachusettsContractorThis includes but not limited to developing tools for deeper understanding of the underlying biological phenomena that lead to differences in product quality (e.g., via metabolic flux modeling, proteomics modeling, bio-informatics); develop robust spectral models correlating to valuable metabolites, cell mass, and product quality attributes (e.g., chemometric models for NIR, Raman). To reach that goal, we are exploring the application of state of the art data science and machine learning while leveraging available process knowledge and a wealth of development and manufacturing data to build end to end product quality predictive meta-models.
Senior Scientist in ML Methods for Spatial Biology Bristol-Myers Squibb CoSenior Scientist in ML Methods for Spatial BiologyMA$148,210–$179,601 / yearIPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learning-across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
Machine Learning Engineer - Computational Drug Discovery 5AM VenturesMachine Learning Engineer - Computational Drug DiscoveryWatertown, MAOur team is dedicated to the development of a broad pipeline of small molecules powered by unique chemistry insights to address a wide range of highly unmet clinical needs. The ideal candidate is comfortable operating across disciplines, takes pride in building reliable systems, and appreciates the opportunity to have a direct impact on scientific decision-making.
Associate Scientist / Scientist I, Computational Test Development PrecedeAssociate Scientist / Scientist I, Computational Test DevelopmentBoston, MassachusettsWe are pioneering an advanced, minimally invasive, comprehensive epigenomics platform with the potential to profoundly impact the research and development of new medicines and the use of approved medicines in clinical practice across a number of conditions, including cancer. MSc in computational biology, bioinformatics, biostatistics, or a closely related quantitative field with 3–4 years of industry or post-graduate research experience in a data-intensive biological or biomedical setting, Ph.
Data Scientist ModernaTXData ScientistCambridge, MassachusettsSupport and execute on research projects that leverage internal and external assay data to impact teams, processes, and projects in Biological Sciences, RNA Sciences, Chemistry and Delivery Sciences, and Bioinformatics, via data analysis and visualization, algorithm development, machine learning, and experimental design. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Senior Scientist I, Data Science Senda BiosciencesSenior Scientist I, Data ScienceCambridge, MA$130,000–$170,000 / yearAs a key member of the Sail Biomedicines Data Science team, the Senior Scientist I will operate at the interface of platform and program, applying data-driven approaches to champion broad platform efforts and hands-on analysis of preclinical datasets to transform the treatment landscape for autoimmune diseases, and beyond. Join our team and drive the future of programmable eRNATM therapeutics and In Vivo CAR-T therapies- where AI-driven biology, targeted delivery systems and next-generation immunotherapy converge to redefine what's possible for patients.
Associate Scientist / Scientist I, Computational Test Development Precede Biosciences, Inc.Associate Scientist / Scientist I, Computational Test DevelopmentBoston, MA$110,000–$150,000 / yearWe are pioneering an advanced, minimally invasive, comprehensive epigenomics platform with the potential to profoundly impact the research and development of new medicines and the use of approved medicines in clinical practice across a number of conditions, including cancer. MSc in computational biology, bioinformatics, biostatistics, or a closely related quantitative field with 3-4 years of industry or post-graduate research experience in a data-intensive biological or biomedical setting, Ph.
Senior Scientist, Computational Biology - Contract Tessera TherapeuticsSenior Scientist, Computational Biology - ContractSomerville, MA$74–$80 / hourHis group supports drug candidate programs through genotoxicity risk assessment, develops computational approaches to study gene writing biology, and builds scalable data and analysis infrastructure to support molecular assay design and knowledge mining. Broad knowledge of genome editing technologies and associated off-target discovery assays (i.e. WGS; targeted sequencing; GUIDE-seq, Digenome-seq discovery / verification; large and small structural variations and translation effects; NGS QC).
Senior Scientist I, Translational Research TempusSenior Scientist I, Translational ResearchBoston, MA$100,000–$160,000 / yearDemonstrated ability to influence without authority (both with internal and external stakeholders Proactive mindset that bridges ideas to implementable solutions, and can help move both internal and external stakeholders to quickly solve problems Experience with communicating insights and presenting concepts to diverse audiences. Work with Product and Engineering teams to streamline workflow of computational analyze Contribute to the development of the portfolio by providing feedback to leadership regarding client responses and suggestions; maintain a solution-oriented mindset.
NewComputational Research Associate Brigham and Women's HospitalComputational Research AssociateBoston, MA$53,040–$75,888.80 / yearThe framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. This is an excellent opportunity for a motivated early-career researcher to develop advanced computational skills, build a strong publication record, and be a part of a world-class research community at MGH, HMS, and the Broad Institute.
Senior Director - Biointelligence Amgen Inc.Senior Director - BiointelligenceCambridge, MAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. This role requires a leader with deep expertise in machine learning for biological systems, experience building and mentoring high-performing scientific teams, and a track record of translating advanced computational methods into impactful research capabilities.