Principal Product Designer MoonpigPrincipal Product DesignerManchester, NHWe’re proud to have a number of employee-led groups driving this forward, including our LGBTQ+, Gender Balance, Neurodiversity and EMBRACE (Educating Myself for Better Racial Awareness and Cultural Enrichment) communities, plus our Group-wide EDI committee. Wellbeing First: Private healthcare (UK) and mental health support ️ Flexible Working & Time Off: Generous holidays, hybrid working (1-3 days in office, depending on role/team) & up to 20 days of international working.
Principal Noise Consultant AcentechPrincipal Noise ConsultantCambridge, MA$115,000–$145,000 / yearAcentech, a multidisciplinary design consulting firm specializing in acoustics, vibration, audiovisual systems, IT and security system design seeks to hire a senior- to principal-level consultant to work with our Noise and Vibration team. We foster a collaborative environment of diverse talent, and encourage people of color, lesbian, gay, bisexual, transgender, queer and non-binary people, neurodivergent, veterans, parents, and individuals with disabilities to apply.
Principal Program Scheduler Torch Technologies, Inc.Principal Program SchedulerHanscom Air Force Base, MA$145,000–$160,000 / yearBy enabling aircrews to electronically receive and process tasking orders, intelligence inputs, target coordinates, and mission‑critical flight and weapons data, MPS enhances combat effectiveness, increases sortie generation rates, and improves aircrew readiness and survivability across the Combat Air Forces (CAF) and Mobility Air Forces (MAF). Several factors can influence the salary for a position including but not limited to, Federal Government contract labor categories and contract wage rates, geographic location, business considerations, scope and responsibilities of the position, local or other applicable market conditions, and internal equity.
Principal System Architect TE Connectivity plcPrincipal System ArchitectMarlborough, MARemote$177,800–$266,600 / yearDrive thought leadership by educating and influencing internal and external stakeholders, from executives and product teams to key decision-makers in customer organizations, on emerging industry trends, TE's technical capabilities, and high-value engineering solutions. Serve as the primary technical liaison for TE's customers, actively engaging with hyperscalers, OEMs, and system architects to gain deep insights into next-generation compute, AI, storage, and networking challenges.
Principal Scientist SanofiPrincipal ScientistWaltham, MA$122.25–$176.58 / hourThe Genomic Medicine Unit (GMU) CMC group at Sanofi is dedicated to the establishment of best-in-class manufacturing platforms to support development of life-changing advanced cell and gene therapy products, including recombinant AAV vectors, lentiviral vectors and cell therapy products. Main responsibilities: Lead scale-up activities from bench scale to pilot scale (200L-2000L), applying engineering principles (mixing, mass transfer, shear stress, dissolved oxygen control) to ensure process comparability at large scale.
Principal Scientist, Antibody Discovery and Engineering ModernaTXPrincipal Scientist, Antibody Discovery and EngineeringCambridge, MassachusettsThis individual will operate with a high degree of independence, scientific judgment, and cross-functional influence while partnering with antigen design, structural and computational biology, Immuno-oncology and Autoimmune Therapeutics research leadership, project teams, and external CRO partners. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Principal Scientist, Computational Protein Design ModernaTXPrincipal Scientist, Computational Protein DesignCambridge, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. This individual will work in close partnership with structural biology, directed evolution, immunology, translational science, and program teams to advance platform innovation and therapeutic programs across Moderna’s Research and Early Development portfolio.
Principal Program Manager – Embedded Aerospace Systems - 3643776 HRU-TechPrincipal Program Manager – Embedded Aerospace Systems - 3643776Hudson, New HampshireIn this role you will lead highly diverse cross functional teams composed of contracts, program planning, finance, operations, and engineering, to develop next-generation high-performance embedded processing solutions. You will support programs across our Compute Line of Business, where we design, develop, and produce embedded computers, networking appliances, storage solutions, and integration processing subsystems.
Principal Embedded Software Engineer Lexington Medical, Inc.Principal Embedded Software EngineerBedford, MA$180,000–$220,000 / yearThe embedded software operates under tight real-time, safety-critical constraints, directly driving electromechanical subsystems where milliseconds and failure modes matter, and you will be in the lab working through hardware-software integration issues alongside electrical and mechanical engineers, not just reviewing designs from a distance. This is a hands-on role: you will be building the embedded software for our surgical stapling platform yourself, writing code, integrating drivers, and debugging at the hardware level, while also owning the technical architecture and setting the long-term direction for embedded systems across the platform.
Principal RA Associate Devices Fresenius Medical CarePrincipal RA Associate DevicesWaltham, MassachusettsResponsible for preparing FDA submissions necessary for new product approvals/clearances which include Premarket norifictoins-510(k)s, Premarket Approval Applications (PMAs) and supplements, Investigational Device Exemptions (IDEs) submissions. Serves as the primary regulatory resource for change to and prioritization of projects, resource assignment and efficient management of the development and change processes.
Principal Thermal Mechanical Engineer FlexPrincipal Thermal Mechanical EngineerLittleton, MassachusettsThe Principal Mechanical Engineer will provide technical leadership, mentorship, and hands-on expertise in mechanical design, fluid dynamics, and heat transfer but also work closely with customers in communicating the art of the possible with JetCool technology and building a strong customer relationship on a technical level. Lead the initial design, analysis, and optimization of complex fluid systems from concept initial CAD to final detailed CAD and drawing for liquid cooling, including cold plates, pumps, fluids, tubing, and heat exchangers, for the latest computer processing chipsets.
Principal, Data Engineer American TowerPrincipal, Data EngineerWoburn, MADay to day you will design and evolve the enterprise data platform, lead complex solution design, and embed governance enforcement through technical controls. We are seeking a Principal Data Engineer to join American Tower's Information Technology organization's Data & Analytics team.
Principal Scientist, Protein Design ModernaTXPrincipal Scientist, Protein DesignCambridge, MassachusettsThis role will lead the design, execution, and continuous advancement of high-throughput mammalian cell–based screening platforms that interrogate broadly applicable design principles for glycoprotein antigens, enabling antigen optimization, improved expression and durability across multiple programs, and rapid maturation of computationally designed candidates. The candidate in this position will work closely with and report to the Senior Director, Computational Design and In Vitro Selection, and will also work closely with the VP, Protein Design, as well as other members of Research, to advance novel candidates to the clinic, drive exploratory trials to inform the generation of improved vaccine antigens and explore new concepts for mRNA medicines.
Principal FPGA Engineer Ayo SemiconductorPrincipal FPGA EngineerBoston, MassachusettsOur photonic processors will provide orders of magnitude improvement in speed and power efficiency in comparison to conventional digital compute platforms by taking advantage of the natural parallelism, speed and energy efficiency of light. Support the hardware team by performing FPGA trade studies and assessing the viability of proposed pin mappings on developmental circuit card assemblies.
Principal Software Engineer Boston Human Capital PartnersPrincipal Software EngineerBoston, MassachusettsRemoteThis role centers on building high-performance distributed systems, powering data-intensive services, and enabling seamless, secure integrations across modern IT and security ecosystems. only) and best suited for engineers who excel in fast-moving startup environments where autonomy, rapid iteration, and strong technical judgment are essential.
Principal Engineer - Security Products, Security Visibility DigitalOceanPrincipal Engineer - Security Products, Security VisibilityBoston, MARemote$235,200–$294,000 / yearEvolve the Audit Logging Platform: Lead the redesign of DigitalOcean's audit log infrastructure to support immutable, tamper-evident, compliance-grade event records with fine-grained retention controls, cross-account federation, and real-time streaming access for customers and internal security teams. Core Experience: You possess over 10 years of software engineering expertise, including 4+ years dedicated to audit logging, security telemetry, SIEM integration, or managing high-throughput data pipelines within cloud or IaaS ecosystems.
Principal Specialist, Quality Assurance Cardinal HealthPrincipal Specialist, Quality AssuranceMansfield, MassachusettsCross-functional Collaboration: Leads complex cross-functional projects to identify root causes of significant quality issues, educates stakeholders on quality requirements, and develops sustainable solutions to minimize future risks. The Principal Specialist, Quality Assurance, is a highly experienced individual contributor who applies advanced knowledge of quality assurance concepts and technical capabilities to drive uncompromised laboratory integrity and minimize risks.
Principal Engineer, Core Infrastructure KlaviyoPrincipal Engineer, Core InfrastructureBoston, MA$244,000–$366,000 / yearIn addition to base salary, our total compensation package may include participation in the company's annual cash bonus plan, variable compensation (OTE) for sales and customer success roles, equity, sign-on payments, and a comprehensive range of health, welfare, and wellbeing benefits based on eligibility. AI‑enabled platform: Approved AI tooling is integrated into IDE/CI/CD with repo policies and auditability; 70% MAU among eligible engineers; MTTR down 20-30% via AI‑assisted triage; flaky‑test rate decreases through targeted, AI‑suggested fixes.
Principal C# Engineer / Technical Lead Integrated Computer SolutionsPrincipal C# Engineer / Technical LeadWaltham, MassachusettsICS blends the art of visual design and agile engineering to help our clients develop their products into devices that delight in a wide range of technologies. As a Principal Engineer / Technical Lead, you will be responsible for the design, development, and testing of software products in the Microsoft stack in the MedTech and industrial space.
Principal Software Engineer, Platform Engineering ModernaTXPrincipal Software Engineer, Platform EngineeringCambridge, MassachusettsThis is a senior individual contributor role that combines deep technical execution with cross-functional technical leadership across developers ("Builders"), Cybersecurity, Architecture, AI platform teams, and broader teams to provide scalable, secure, and user-focused capabilities that make the right path the easiest path for Moderna’s engineering teams. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.