Senior Manager, Clinical Business Operations Relay TherapeuticsSenior Manager, Clinical Business OperationsCambridge, MA$124,000–$177,000 / yearYou will work with the clinical study leads and cross-functional teams to establish governance process, which may include joint oversight committees, with key clinical vendors to monitor service levels and key performance indicators and manage issue escalation and resolution. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology.
NewSenior Manager, Clinical Study Operations Beacon BiosignalsSenior Manager, Clinical Study OperationsBoston, Massachusetts$115,000–$135,000 / yearManage Beacon's day-to-day working relationship with sponsors — and, where applicable, a CRO intermediary — on the studies your direct reports run, and step in to represent Beacon directly with the sponsor when a study lead escalates a decision that needs strategic alignment or sign-off. You are expected to bring hands-on clinical trial operations experience — enough to guide your direct reports through site and vendor issues, coach sound day-to-day tradeoffs, and step in directly on complex or high-stakes situations when needed.
NewManager, Clinical Study Operations Beacon BiosignalsManager, Clinical Study OperationsBoston, MassachusettsManage Beacon's day-to-day working relationship with sponsors — and, where applicable, a CRO intermediary — on the studies your direct reports run, and step in to represent Beacon directly with the sponsor when a study lead escalates a decision that needs strategic alignment or sign-off. You are expected to bring hands-on clinical trial operations experience — enough to guide your direct reports through site and vendor issues, coach sound day-to-day tradeoffs, and step in directly on complex or high-stakes situations when needed.
NewSr. Director, Clinical Operations Flagship Pioneering, Inc.Sr. Director, Clinical OperationsSomerville, MA$213,000–$280,000 / yearRepresent Clinical Operations on cross-functional study and program teams, partnering with other relevant functions internally and externally (e.g., Clinical Development, Regulatory, Safety, Clinical Pharmacology, Data Management, Biostatistics, Bioanalytical, CMC, Quality, and clinical supply colleagues). The successful candidate will be highly operational, able to ramp quickly, and comfortable establishing fit-for-purpose capabilities while working across internal teams, external partners, and consultants to move studies forward with urgency and rigor.
Sr. Director, Clinical Operations Flagship Pioneering IncSr. Director, Clinical OperationsSomerville, MA$213,000–$280,000 / yearRepresent Clinical Operations on cross-functional study and program teams, partnering with other relevant functions internally and externally (e.g., Clinical Development, Regulatory, Safety, Clinical Pharmacology, Data Management, Biostatistics, Bioanalytical, CMC, Quality, and clinical supply colleagues). The successful candidate will be highly operational, able to ramp quickly, and comfortable establishing fit-for-purpose capabilities while working across internal teams, external partners, and consultants to move studies forward with urgency and rigor.
Director/Sr. Director, Clinical Operations Lead Paratus Sciences CorporationDirector/Sr. Director, Clinical Operations LeadBoston, MA$180,000–$275,000Demonstrated track record leading early phase trials, including FIH and Phase 1/2 studies; Proven ability to manage CROs and cross-functional clinical programs end-to-end from vendor selection through study close-out. This is not a role for a process follower, it is a role for a dynamic builder and operator who can translate a clinical development strategy into executable programs, establish the infrastructure that scales with us, and lead with equal parts strategic judgment and hands-on accountability.
Clinical Operations Senior Manager Kiniksa PharmaceuticalClinical Operations Senior ManagerLexington, MAYou will join a dynamic Clinical Operations team working in a fast-paced, highly collaborative environment, with the opportunity to help shape how we deliver high-quality clinical programs and contribute to the future success of the organization. The Senior Manager, Clinical Operations provides / supports the operational leadership and strategic oversight of the planning, conduct, and delivery of global clinical trials.
Director, Clinical Operations Generate Biomedicines IncDirector, Clinical OperationsMA$186,000–$279,000 / yearBy unifying computational design and clinical development within a single operating model, we translate this approach into clinical-stage programs and are leading a shift from traditional drug discovery toward systematic drug generation. The submission of unsolicited resumes by recruitment or staffing agencies to Generate:Biomedicines or its employees is strictly prohibited unless contacted directly by the Company's internal Talent Acquisition team.
Director, Clinical Operations AlkermesDirector, Clinical OperationsWaltham, MARemote$219,000–$235,000 / yearThe Director will partner closely with Clinical Pharmacology, Translational Medicine, Medical, Biometrics, Regulatory Affairs, Clinical Supply, Quality Assurance, Pharmacovigilance, and CRO partners to ensure successful execution of first-in-human (FIH), SAD, MAD, food effect, relative bioavailability, DDI, QTc, and other early development studies in healthy volunteers. The successful candidate will be responsible for study budgets, forecasting, resource planning, operational strategy, inspection readiness, eTMF oversight, vendor management, and continuous process improvement and proactive risk identification to ensure on-time delivery of quality trials that meet the highest level of compliance.
Director, Clinical Operations Alkermes PlcDirector, Clinical OperationsWaltham, MARemoteThe Director will partner closely with Clinical Pharmacology, Translational Medicine, Medical, Biometrics, Regulatory Affairs, Clinical Supply, Quality Assurance, Pharmacovigilance, and CRO partners to ensure successful execution of first-in-human (FIH), SAD, MAD, food effect, relative bioavailability, DDI, QTc, and other early development studies in healthy volunteers. The successful candidate will be responsible for study budgets, forecasting, resource planning, operational strategy, inspection readiness, eTMF oversight, vendor management, and continuous process improvement and proactive risk identification to ensure on-time delivery of quality trials that meet the highest level of compliance.
Clinical Operations Lead Quilt Health IncClinical Operations LeadBoston, MAYou will bridge the gap between healthcare delivery and fast-moving software engineering-translating complex clinical nuances into structured data requirements, intuitive patient onboarding journeys, actionable product feedback and exceptional patient and clinician experiences and outcomes. Sitting at the critical intersection of digital product development, health system data collection, and patient/caregiver experience, you will report directly to the CEO and act as the clinical engine guiding our product team and the development of our patient and clinician support operations.
Director, Clinical Business Operations Rapport Therapeutics IncDirector, Clinical Business OperationsBoston, MA$230,000–$255,000 / yearYou''ll partner across the organization to turn strategy into action, develop scalable ways of working, and ensure our teams have the resources, insights, and operational support they need to bring innovative therapies to patients. Your day-to-day: Lead the business operations function for Clinical Operations, providing strategic oversight of budgets, forecasting, contracts, vendor management, resource planning, and portfolio governance.
Director/Sr. Director, Clinical Operations - Oncology Programs Frontier Medicines CorpDirector/Sr. Director, Clinical Operations - Oncology ProgramsBoston, MAFrontier Medicines is seeking two experienced Clinical Operations leaders, at the Director or Senior Director level, to drive the operational strategy and execution of our oncology programs as they advance through clinical development. The ideal candidate brings deep oncology experience, strong global study oversight, and the ability to influence stakeholders, anticipate challenges, and deliver results in a dynamic biotech environment.
Director of Clinical Operations (Registered Dietitian) Healthcare Services Group, Inc.Director of Clinical Operations (Registered Dietitian)Boston, Massachusetts$85,000–$95,000 / yearAble to effectively communicate (both written and oral) with clients, physicians, staff, residents, residents’ families, consultants, and corporate staff with respect to clinical aspect of dietary services. Overview: Healthcare Services Group (HCSG) typically services long term care and nursing facilities and is now hiring a Director of Clinical Operations (Registered Dietitian) in your area!
NewMedical & Clinical Affairs (MACA) Operations Specialist Sirtex Medical LtdMedical & Clinical Affairs (MACA) Operations SpecialistWoburn, MA$76,000–$95,000 / yearBuild and maintain strong relationships with internal stakeholders, healthcare professionals, investigators, study teams, vendors, and cross-functional partners to ensure successful execution of Medical Affairs and Clinical Affairs initiatives. Manage the end-to-end administration of educational grants, fellowship grants, and investigator-sponsored research (ISR) programs, including application intake, review coordination, contract administration, budget tracking, reconciliation, and project closeout.
Director of Nursing & Clinical Operations CbDirector of Nursing & Clinical OperationsBoston, MassachusettsAs Atulo continues to grow, we are seeking an experienced Director of Nursing & Clinical Operations to help lead our nursing organization, strengthen clinical operations, and build systems that allow us to scale effectively. When a recurring clinical or operational problem arises, the Director provides oversight and direction to nursing staff while ensuring professional development, quality outcomes, excellence in the patient experience, and increasing workforce engagement.
Junior Clinical Operations Associate (College Grad 2027) Find Solace IncJunior Clinical Operations Associate (College Grad 2027)Boston, MASolace cuts through the red tape of healthcare by pairing patients with expert advocates and giving them the tools to make better decisions-and get better outcomes. Clinical or healthcare interest is a significant plus-itll help you understand context faster and build better systems, but we care more about operational chops than clinical credentials.
Senior Process Engineer, Clinical Operations Elucid Bioimaging IncSenior Process Engineer, Clinical OperationsBoston, MARemoteWe are a rapidly growing, Boston-based medical technology company using AI to enable clinicians to make informed decisions on cardiovascular care - leading to better patient outcomes, improved quality of care, and reduced healthcare costs. Youll work hand-in-hand with our talented 3D CT analysts, as well as our Clinical QA, Software QA, and Product Management teams to propel our clinical operations to new heights as we rapidly scale and commercialize.
Associate Director, Clinical Operations Generate Biomedicines IncAssociate Director, Clinical OperationsMA$162,000–$227,000 / yearThe candidate will focus on site- and Contract Research Organization (CRO)-facing interactions to ensure smooth execution of studies, including start-up, drug and budget forecasting, and acquisition of detailed, high-quality clinical (including safety and efficacy) and translational data to support evaluation of the drugs under study. Develop and manage study timelines, working with internal partners (including but not limited to clinical development, clinical pharmacology and other quantitative functions, data management, biomarkers and translational, CMC, regulatory affairs and project management).
Clinical Strategy and Operations Lead (MBA Grad 2027) SolaceClinical Strategy and Operations Lead (MBA Grad 2027)Boston, MassachusettsReporting directly to the Chief Medical Officer’s Chief of Staff you'll serve as a strategic partner across the organization, leading high-impact, cross-functional initiatives that enhance clinical quality, accelerate growth, and expand our service offerings. Exceptional analytical, project management, and business development skills, with proven ability to break down complex problems, develop compelling business cases, and analyze operational data to drive decision-making.