Vos is focused on solving metabolic dysfunction-associated steatotic liver disease (MASLD) and the early onset of insulin resistance, dyslipidemia and cardiovascular disease risk in children through clinical and translational studies on prevention, precision nutri-genomics, stable-isotope tracing, diagnostics, biomarkers, therapeutics, and outcomes. Methods used in our research group vary widely from randomized clinical trials to multi-omics explorations, imaging, biomarker development, stable-isotope tracers, large-scale data sets + machine learning and digital twins.