Senior/Staff AI Scientist (Polytope Bio) Astera InstituteSenior/Staff AI Scientist (Polytope Bio)Emeryville, CaliforniaUnlike traditional non-profit research organizations, projects supported by Astera operate like high-velocity startups, allowing us to focus on ambitious goals, match structure to problem, and attract strong technical talent and leadership. The researcher in this role will work hands-on to develop and publish new reinforcement learning methods and generative AI models leveraging datasets created by our unique high-throughput biology platform.
Scientist, Applications Sample Preparation Glyphic BiotechnologiesScientist, Applications Sample PreparationBerkeley, CaliforniaReporting to the Director of Assay Integration, you will execute and refine established sample preparation protocols across a broad range of biological inputs and generate high-quality data that supports ProSE performance benchmarking and Glyphic’s broader multi-omic strategy, combining ProSE, RNA-seq, DNA-seq, Ribo-seq, and mass spectrometry to identify neoantigens, biomarkers, and drug targets. We are seeking a technically driven, detail-oriented, and collaborative Scientist to apply and optimize sample preparation workflows across Glyphic’s single-molecule protein sequencing platform (ProSE), as well as complementary DNA sequencing, RNA sequencing, and mass spectrometry-based proteomics workflows.
Lead Bioinformatics Scientist, NGS ProfluentLead Bioinformatics Scientist, NGSEmeryville, CA$160,000–$230,000 / yearFounded in 2022 and headquartered in Emeryville, CA, Profluent is backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures and has raised over $150M to date. You'll work at the intersection of computational biology, software engineering, and experimental biology to build scalable systems that extract clear, actionable insights from large-scale sequencing data.
Staff / Senior Scientist, Assay Development (Chemistry) Glyphic BiotechnologiesStaff / Senior Scientist, Assay Development (Chemistry)Berkeley, CaliforniaReporting to the Director of Assay Development, you will be a hands-on expert working at the chemistry-assay interface — developing the chemical methods that enable reliable, high-efficiency sample loading into our expansion assay, and building the novel conjugation, cleavage, and stabilization workflows that power our single-molecule proteome sequencing platform. Demonstrated experience developing site-selective bioconjugation chemistry for native peptides — including N-terminal, C-terminal, and side-chain modification strategies — using click chemistry (CuAAC, SPAAC, IEDDA), NHS-ester coupling, and related bioorthogonal approaches in multi-component peptide systems.
Analytical Chemistry Scientist Octant BioAnalytical Chemistry ScientistEmeryville, CA$135,000–$155,000 / yearIdentify, develop, and deploy chromatographic and mass spectrometric methodologies - including reversed-phase, HILIC, SFC, and 2D-LC/MS separations - to analyze small molecules to support both our in-house high throughput synthesis capabilities and ADME/PK property characterization. The Navigator is an expanding set of drug discovery and development capabilities with three interwoven components that operate together: Generative Biology- Multiplexed measurements from engineered sensors in human cells to understand cellular mechanisms.
AI Data Scientist-Furman lab Buck Institute for Research on AgingAI Data Scientist-Furman labNovato, CA$60,000–$75,000 / yearThe successful candidate will contribute to multiple government-funded and institutional research initiatives, including a recently launched, government-funded project focused on using large-scale human data to better understand biological aging, resilience, healthspan, and age-related disease risk. Globally recognized as a pioneer and leader in efforts to target aging - the number one risk factor for diseases including Alzheimer's disease, Parkinson's disease, cancer, macular degeneration, heart disease, and diabetes - the Buck seeks to help people live better longer.
Manufacturing Scientist, Reagent Manufacturing Ansa BiotechnologiesManufacturing Scientist, Reagent ManufacturingEmeryville, CA$42–$47 / hourYou will also support protein production by executing and scaling downstream protein purification processes from bench scale through pilot scale, including chromatographic capture and polishing, process-scale purification, and TFF-based UF/DF for concentration, buffer exchange, and final product formulation. Execute and scale downstream protein purification processes from R&D through pilot scale, including chromatographic capture and polishing steps, process-scale purification, and TFF-based ultrafiltration/diafiltration (UF/DF) for concentration, buffer exchange, and final product formulation.
AI Data Scientist-Furman lab Buck InstituteAI Data Scientist-Furman labNovato, CAFull timeThe successful candidate will contribute to multiple government-funded and institutional research initiatives, including a recently launched, government-funded project focused on using large-scale human data to better understand biological aging, resilience, healthspan, and age-related disease risk. Globally recognized as a pioneer and leader in efforts to target aging — the number one risk factor for diseases including Alzheimer’s disease, Parkinson’s disease, cancer, macular degeneration, heart disease, and diabetes — the Buck seeks to help people live better longer.
AI Data Scientist-Furman Lab Buck InstituteAI Data Scientist-Furman LabNovato, CA$60,000–$75,000 / yearThe successful candidate will contribute to multiple government-funded and institutional research initiatives, including a recently launched, government-funded project focused on using large-scale human data to better understand biological aging, resilience, healthspan, and age-related disease risk. Globally recognized as a pioneer and leader in efforts to target aging - the number one risk factor for diseases including Alzheimer's disease, Parkinson's disease, cancer, macular degeneration, heart disease, and diabetes - the Buck seeks to help people live better longer.
Analytical Chemistry Scientist Octant IncAnalytical Chemistry ScientistEmeryville, CA$135,000–$155,000 / yearIdentify, develop, and deploy chromatographic and mass spectrometric methodologies - including reversed-phase, HILIC, SFC, and 2D-LC/MS separations - to analyze small molecules to support both our in-house high throughput synthesis capabilities and ADME/PK property characterization. The Navigator is an expanding set of drug discovery and development capabilities with three interwoven components that operate together: Generative Biology - Multiplexed measurements from engineered sensors in human cells to understand cellular mechanisms.
Manufacturing Scientist, Reagent Manufacturing Ansa Biotechnologies IncManufacturing Scientist, Reagent ManufacturingEmeryville, CA$42–$47 / hourAs a member of our manufacturing team, you will also be responsible for making process improvements, e.g., setting appropriate QC metrics, authoring and revising formulation, QC and raw material acceptance batch records, and mentoring other manufacturing associates. Our enzyme-based approach (published in Nature Biotechnology) promises to dramatically accelerate innovation in biological research and biotechnology, including therapeutics, diagnostics, biomanufacturing, and synthetic biology.
Quantitative Biologist Arcadia ScienceQuantitative BiologistEmeryville, CA$150,000–$200,000 / yearWe are seeking a Quantitative Biologist to join our Validation team with strong expertise in using computational analyses across modalities and biological scales to extract meaning from complex data, identifying the limits of existing analytical approaches, and developing new ones to address them. Your contributions will be instrumental in validating existing tools at Arcadia, shaping how we design and interpret experiments, identifying potential assets, and building robust analytical infrastructure that scales across the team.
Scientist / Senior Scientist, Assay Development (Reagents) Glyphic BiotechnologiesScientist / Senior Scientist, Assay Development (Reagents)Berkeley, CaliforniaDevelop, qualify, and transfer QC test methods for reagent characterization and lot release, including HPLC, fluorescence-based functional assays, and physical characterization methods; set product, process, and incoming material acceptance criteria in collaboration with Assay and cross-functional partners. Experience establishing and maintaining robust SOPs for end-to-end integrated workflows, with consistent capture of key experimental variables, reagents, and process conditions — enabling cross-functional traceability and correlation with downstream data and performance.