Senior Manager, Clinical Study Quality Lead (Hybrid) Vertex Pharmaceuticals IncSenior Manager, Clinical Study Quality Lead (Hybrid)Boston, MARemote$137,800–$206,800 / yearGeneral Summary: The Senior Manager, Clinical Study Quality Lead provides study-level quality oversight for assigned clinical trials to help ensure they are conducted in compliance with Good Clinical Practice (GCP), applicable global regulations, study protocols, and Vertex procedures. This is an individual contributor role focused on GCP quality assurance oversight for clinical trials, including risk-based audit strategy, quality risk identification, issue escalation, CAPA support, compliance trend analysis, and inspection readiness.
NewCybersecurity Principal Engineer - HYBRID ROLE Vertex PharmaceuticalsCybersecurity Principal Engineer - HYBRID ROLEBoston, MassachusettsRemoteThe Principal Cybersecurity Engineer will partner closely with cybersecurity, infrastructure, cloud, application, and enterprise technology teams to strengthen security architecture, improve platform effectiveness, enhance automation, and support secure modernization efforts. The Principal Cybersecurity Engineer, Core Security Infrastructure is a technical leader responsible for shaping and advancing Vertex’s core security capabilities across network, cloud, application, AI, SaaS, and hybrid environments.
NewCybersecurity Principal Engineer - Hybrid Role Vertex Pharmaceuticals, IncCybersecurity Principal Engineer - Hybrid RoleBoston, MARemote$147,600–$221,400 / yearThe Principal Cybersecurity Engineer will partner closely with cybersecurity, infrastructure, cloud, application, and enterprise technology teams to strengthen security architecture, improve platform effectiveness, enhance automation, and support secure modernization efforts. The Principal Cybersecurity Engineer, Core Security Infrastructure is a technical leader responsible for shaping and advancing Vertex's core security capabilities across network, cloud, application, AI, SaaS, and hybrid environments.
NewHybrid Remote Cloud Reliability Engineer for Mission-Critical Systems Systems Engineering Solutions Inc DefunctHybrid Remote Cloud Reliability Engineer for Mission-Critical SystemsBoston, MARemoteSystems Engineering Solutions Corporation is seeking a Reliability Engineer to support the U.S. Air Force Cloud One Architecture. The ideal candidate will have a strong background in cloud platforms, incident response, and a commitment to operational excellence.#J-18808-Ljbffr.
Associate Director, AI & Application Security - HYBRID ROLE Vertex Pharmaceuticals IncAssociate Director, AI & Application Security - HYBRID ROLEBoston, MARemote$172,000–$258,000 / yearAt Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. This role is responsible for securing AI throughout the full lifecycle-from design and development to deployment and ongoing operations-including generative AI, agentic workflows, traditional machine learning, and AI embedded in enterprise applications.
Digital Marketing Account Manager (HYBRID) C-4 AnalyticsDigital Marketing Account Manager (HYBRID)Wakefield, MARemoteFull timeAccelerated Growth via Osmosis and Coaching: Learn sales strategies and industry knowledge naturally by hearing colleagues handle calls and receive instant feedback and hands-on guidance from your manager and colleagues during in-person weekly one-on-ones. 2-plus years' experience building multi-faceted digital marketing campaigns, including SEO, SEM, PPC, Social and email marketing services.
Technical Lead - API and Integration Development (Hybrid or Remote - Raleigh, NC) Onebeacon Professional Insurance IncTechnical Lead - API and Integration Development (Hybrid or Remote - Raleigh, NC)Boston, MARemote$144,000–$169,000 / yearYou'll lead a small team while remaining actively involved in coding and solution design, leveraging technologies such as Auth0, Microsoft Azure, Kafka, Event Hub, Service Bus, and Terraform. For candidates located in San Francisco, CA; Washington DC; our Massachusetts based offices and the New York City metro area, the base salary range is $144,000 - $169,000.
Director, Knowledge Graph & Semantics - HYBRID ROLE Vertex Pharmaceuticals IncDirector, Knowledge Graph & Semantics - HYBRID ROLEBoston, MARemote$216,400–$324,600 / yearWe are seeking an experienced engineering leader to build and operate Vertex's enterprise Knowledge Graph and Semantic Layer: the unified, navigable representation of Vertex's data, concepts, and relationships that AI agents and analytical systems traverse to reason over our business. Design, build, and operate Vertex's enterprise knowledge graph spanning clinical, research, regulatory, and commercial domains, including ingestion, storage, query, and lifecycle management of nodes, edges, and properties.
Senior Software Developer (Hybrid or Remote) Onebeacon Professional Insurance IncSenior Software Developer (Hybrid or Remote)MARemote$128,000–$149,000 / yearYou'll architect microservices, craft elegant UIs, and automate CI/CD - all while mentoring a high‑impact squad and partnering with product, design, and underwriting to turn complex needs into simple, scalable software that delights users and moves the business. In return, we promise you support, opportunities and performance-led financial rewards in a flexible work environment where you can: Shape the future: Help us lead an insurance transformation to better protect people, businesses and society.
Director, Agent Intelligence - HYBRID ROLE Vertex Pharmaceuticals IncDirector, Agent Intelligence - HYBRID ROLEBoston, MARemote$216,400–$324,600 / yearYou will own the four primitives that all Vertex agents are built from: agent memory (personal and organizational), personas as code, skills (atomic tools and higher-order compositions), and the flagship agents that put those primitives to work on Vertex's hardest use cases. Design, build, and deploy custom AI agents for Vertex's highest-value enterprise use cases using Snowflake Cortex AI, Databricks AI, and agent orchestration frameworks, using these builds to harden the underlying primitives.
Associate Director, AI & Application Security - Hybrid Role Vertex Pharmaceuticals, IncAssociate Director, AI & Application Security - Hybrid RoleBoston, MARemote$172,000–$258,000 / yearAt Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. This role is responsible for securing AI throughout the full lifecycle-from design and development to deployment and ongoing operations-including generative AI, agentic workflows, traditional machine learning, and AI embedded in enterprise applications.
Director, Knowledge Graph & Semantics - Hybrid Role Vertex Pharmaceuticals, IncDirector, Knowledge Graph & Semantics - Hybrid RoleBoston, MARemote$216,400–$324,600 / yearWe are seeking an experienced engineering leader to build and operate Vertex's enterprise Knowledge Graph and Semantic Layer: the unified, navigable representation of Vertex's data, concepts, and relationships that AI agents and analytical systems traverse to reason over our business. Design, build, and operate Vertex's enterprise knowledge graph spanning clinical, research, regulatory, and commercial domains, including ingestion, storage, query, and lifecycle management of nodes, edges, and properties.
Director, Agent Intelligence - Hybrid Role Vertex Pharmaceuticals, IncDirector, Agent Intelligence - Hybrid RoleBoston, MARemote$216,400–$324,600 / yearYou will own the four primitives that all Vertex agents are built from: agent memory (personal and organizational), personas as code, skills (atomic tools and higher-order compositions), and the flagship agents that put those primitives to work on Vertex's hardest use cases. Design, build, and deploy custom AI agents for Vertex's highest-value enterprise use cases using Snowflake Cortex AI, Databricks AI, and agent orchestration frameworks, using these builds to harden the underlying primitives.