Principal Software Engineer (TS/SCI) {S} ARKA Group, L.P.Principal Software Engineer (TS/SCI) {S}King Of Prussia, PennsylvaniaBeyond direct design, the architect is expected to drive technical consensus through trade studies, proactively identify and mitigate technical risks, act as the primary technical interface to leadership, government customers, and sub-contractor CA/CE’s, and actively participate in the mentorship and growth of the distributed engineering team, ultimately joining our team to help shape the development and delivery of custom solutions and providing significant opportunities for personal skill development at ARKA. ARKA is seeking an accomplished Software Architect/Principal Software Engineer who is deeply customer mission-focused and passionate about providing strategic technical leadership in the software architecture and design of complex government systems, requiring proven experience leading programs involving 30+ developers in a distributed environment.
Principal Technologist (Req#1227) ePlus TechnologyPrincipal Technologist (Req#1227)King Of Prussia, PA$160,000–$210,000 / yearThe position requires a strong understanding of how technology drives business outcomes and enables the development of strategies aligned to customer objectives The Principal Technologist will be involved in the entire sales cycle, including leading meetings to discuss key business and technology issues, assess clients' needs and identify the ePlus targeted product and service solutions that best meet those needs. 8 or more years of experience in designing or implementing complex networks, systems/storage solutions and ability to articulate deep technical knowledge of infrastructure services, data center design and cloud integration for enterprise customers.
Education And Science Principal HDR, Inc.Education And Science PrincipalPennington, NJOur eight Employee Network Groups (Asian Pacific, Black, Hispanic/Latino(a), LGBTQ, People with Disabilities, Veterans, Women, Young Professionals) help create a sense of belonging and foster a supportive environment where everyone is empowered to engage and contribute. At HDR, our employee-owners are fully engaged in creating a welcoming environment where each of us is valued and respected, a place where everyone is empowered to bring their authentic selves and novel ideas to work every day.
Upstream Principal Scientist, Vector Biology Legend Biotech CorpUpstream Principal Scientist, Vector BiologyPhiladelphia, PA$146,410–$192,164 / yearThe Principal Scientist will bring a rare combination of molecular biology depth and bioprocess engineering breadth, functioning as a key technical authority who bridges construct-level design decisions with upstream process outcomes, while closely interfacing with Downstream, Analytical, and Technical Development partners to ensure end-to-end process coherence and readiness for technology transfer. Exemplary oral and written communication skills, with the ability to translate complex early process development findings into compelling scientific narratives for diverse audiences including R&D leadership, CMC colleagues, and cross-functional program teams while operating with equal effectiveness as a self-directed scientific contributor and an engaged collaborative partner.
Principal Network Operations Engineer / IT Operations Specialist (US) TD BankPrincipal Network Operations Engineer / IT Operations Specialist (US)Mount Laurel, New JerseyTotal Rewards at TD includes base salary and variable compensation/incentive awards (e.g., eligibility for cash and/or equity incentive awards, generally through participation in an incentive plan) and several other key plans such as health and well-being benefits, savings and retirement programs, paid time off (including Vacation PTO, Flex PTO, and Holiday PTO), banking benefits and discounts, career development, and reward and recognition. You will serve as a senior technical escalation point, providing hands-on expertise in complex troubleshooting, mentoring team members, and collaborating across engineering, architecture, and application teams to prevent recurrence of incidents.
NewPrincipal Engineer, Architecture & Compound Engineering (US) TD BankPrincipal Engineer, Architecture & Compound Engineering (US)Mount Laurel, New JerseyTotal Rewards at TD includes base salary and variable compensation/incentive awards (e.g., eligibility for cash and/or equity incentive awards, generally through participation in an incentive plan) and several other key plans such as health and well-being benefits, savings and retirement programs, paid time off (including Vacation PTO, Flex PTO, and Holiday PTO), banking benefits and discounts, career development, and reward and recognition. More than 95,000 TD colleagues bring their skills, talent, and creativity to foster deeper relationships, ensure disciplined execution, and build a simpler, faster banking experience.
Principal AI Data Scientist Anaplan IncPrincipal AI Data ScientistPAGenerative AI Architecture: Architect GenAI solutions, focusing on fine-tuning proprietary and open-source Large Language Models (LLMs) via Transformer architectures for specialized enterprise data tasks. Advanced Modeling & Predictive Analytics: Lead the research, design, and implementation of advanced Machine Learning, Deep Learning, and Time Series Forecasting models to solve complex enterprise business and planning challenges.
Senior Principal Scientist, Bioanalytical Outsourcing 6084-Janssen Research & Development Legal EntitySenior Principal Scientist, Bioanalytical OutsourcingSpring House, PennsylvaniaClinical Pharmacology, Clinical Trials Operations, Consulting, Drug Discovery Development, Industry Analysis, Pharmacodynamics, Pharmacokinetics, Pharmacology, Pharmacometrics, Program Management, Report Writing, Researching, Research Proposals, Scientific Research, Tactical Planning, Technical Credibility The candidate will have a successful track record of problem solving, good organizational habits, excellent interpersonal skills, the ability to work under timelines, and the ability to collaborate within multidisciplinary teams is required.
Water/Wastewater Engineer (Mid-to-Principal Level) CHA Consulting, Inc.Water/Wastewater Engineer (Mid-to-Principal Level)Wilmington, Delaware$125,000–$175,000 / yearFull timeWhat You'll Do: Lead all phases of multifaceted water/wastewater infrastructure projects such as treatment plants, collection systems, water distribution, pump stations, pfas treatment, and rehabilitation programs—from concept through completion—by developing advanced engineering designs, technical reports, and contract documentation, while guiding cross-functional teams and mentoring junior engineering staff. Explore how our team is delivering innovative water/wastewater solutions that protect vital resources and strengthen communities by visiting: chasolutions.com/solutions/water-wastewater-sewer/ .
Principal Data Scientist - Immunology - (2 positions) 6084-Janssen Research & Development Legal EntityPrincipal Data Scientist - Immunology - (2 positions)Titusville, New JerseyRemoteWork with Data Science & Digital Health colleagues, IT and DevOps teams to deploy and manage the graph database infrastructure, focusing on high availability, scalability, and recovery operations specifically geared toward Immunology R&D needs and applications. Cambridge, Massachusetts, United States of America, Raritan, New Jersey, United States of America, San Diego, California, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America Job Description:
Principal Data Scientist - AI Anaplan IncPrincipal Data Scientist - AIPADesign and build the storage and processing layers powering our analytics workloads: data lakes, data warehouses, distributed file systems, and real-time streaming architectures. You''ll need deep knowledge of distributed computing, data architecture, and strong software engineering skills to tackle complex, high-scale data challenges.
NewPrincipal Scientist, AI & Autonomous Discovery Systems - Spring House, PA 6084-Janssen Research & Development Legal EntityPrincipal Scientist, AI & Autonomous Discovery Systems - Spring House, PASpring House, PennsylvaniaRemoteJohnson & Johnson Innovative Medicine is recruiting for a Principal Scientist, AI & Autonomous Discovery Systems, to advance AI-powered drug discovery through human-guided autonomous and agentic discovery platforms and help accelerate drug discovery by creating AI-enabled Design-Make-Test-Learn ecosystems that improve scientific decision quality, increase experimental throughput, reduce cycle times, and advance high-value therapeutic programs. Define the technical vision, long-term strategy, and scalable multi-agent architecture for AI-driven laboratory orchestration and human-guided autonomous discovery systems, coordinating scientific reasoning, knowledge retrieval, experiment planning, model execution, workflow automation, and decision support while influencing investments across discovery platforms, therapeutic areas, and enterprise AI initiatives.
SAP FSCM Principal Specialist TandymSAP FSCM Principal SpecialistWilmington, Delaware$150,000–$170,000A manufacturing company in Delaware is looking to add a new SAP FSCM Principal Specialist to their team in Wilmington, focusing on designing and implementing enterprise technology solutions. Configure credit master data, credit rules, and automated credit exposure processes.
Principal Scientist, High-Content Imaging 6084-Janssen Research & Development Legal EntityPrincipal Scientist, High-Content ImagingSpring House, PennsylvaniaAdditional responsibilities include building and implementing data generation pipelines, troubleshooting complex experiments at the bench and across imaging platforms, optimizing protocols, analyzing imaging data, and collaborating with internal teams, CROs, and external technology partners to support capability development. The ideal candidate will be a hands-on technical contributor responsible for developing, validating, and deploying cutting-edge high-content imaging capabilities to advance therapeutic discovery across the Immunology, Neuroscience, and Oncology portfolios.
Principal Account Executive (Wealth) iPipelinePrincipal Account Executive (Wealth)Wayne, PennsylvaniaFull timeHas a strong command of core broker-dealer workflows like account opening, advisory processes, and annuity order entry, and can pinpoint where clients struggle operationally and clearly explain how the Company's platform solves those problems. With one of the industry’s largest data sets, we help advisors/advisers and agents to transform paper and manual operations into a secure, seamless digital experience – from proposal to commission– so they can help better secure the financial futures of their clients.
Tech Support Principal Engineer AVEVA Group PlcTech Support Principal EngineerPhiladelphia, PA$82,400–$170,400 / yearFrom industry experts and solution architects to sales, support, success managers, and business operations, everyone shares a common goal: to deeply understand our customers' needs and deliver tailored solutions. The Technical Support Team provides constructive, added-value advice that guides users to the information they want, helps them make sense of their data, and educates them in making the best use of the tools.
NewPrincipal Data Engineering - Remote - CST UnitedHealth Group Inc.Principal Data Engineering - Remote - CSTPhiladelphia, PARemote$112,700–$193,200 / yearDeploy AI and Data-Driven Solutions: Develop and deploy large-scale data pipelines empowering machine learning algorithms, insights generation, business intelligence dashboards, reporting, and new data products while utilizing enterprise-approved AI tools to address complex business challenges. Working with advanced platforms such as Azure Databricks, Snowflake, and LLMs, you will build data solutions that empower machine learning, insights generation, and business automation, directly contributing to better clinical and administrative connectivity across the healthcare system.
Upstream Principal Scientist, Vector Biology Legend Biotech USUpstream Principal Scientist, Vector BiologyPhiladelphia, PAThe Principal Scientist will bring a rare combination of molecular biology depth and bioprocess engineering breadth, functioning as a key technical authority who bridges construct-level design decisions with upstream process outcomes, while closely interfacing with Downstream, Analytical, and Technical Development partners to ensure end-to-end process coherence and readiness for technology transfer. Working knowledge of downstream processing operations —encompassing harvest and clarification strategies, affinity and ion-exchange chromatography, and tangential flow filtration — with the scientific acuity to incorporate purification process requirements and vector quality attribute targets into upstream process design; experience in integrated upstream-downstream process development is preferred.
Principal Account Executive iPipelinePrincipal Account ExecutiveWayne, PennsylvaniaFull timeWith one of the industry’s largest data sets, we help advisors/advisers and agents to transform paper and manual operations into a secure, seamless digital experience – from proposal to commission– so they can help better secure the financial futures of their clients. Overview: As a global market leader, iPipeline combines technology, innovation, and expertise to deliver ground-breaking, award-winning software solutions that transform the life insurance, financial services, and protection industries.
Principal Scientist, In-vivo CAR-T 6084-Janssen Research & Development Legal EntityPrincipal Scientist, In-vivo CAR-TMalvern, PennsylvaniaAnalytical Reasoning, Biochemistry, Biotechnology, Chemistry, Manufacturing, and Control (CMC), Clinical Research and Regulations, Clinical Trial Designs, Coaching, Critical Thinking, Drug Discovery Development, Emerging Technologies, Molecular Diagnostics, Organizing, Pharmacovigilance, Presentation Design, Process Improvements, Productivity Planning, Scientific Research Collaborate with modelling experts and data scientists to identify opportunities where modelling or machine learning can reduce experimental burden, improve robustness, or define process design space.