Director (Principal Scientist), Clinical Research, Respiratory Merck & Co IncDirector (Principal Scientist), Clinical Research, RespiratoryBoston, MA$255,800–$402,700 / yearThe Clinical Director is responsible for maintaining a strong scientific fund of knowledge by: Maintaining awareness of scientific developments within his/her area of expertise, in terms of new scientific findings, research methodologies. The Clinical Director (Principal Scientist) has primary responsibility for planning and directing clinical research activities involving new or marketed medicines in the Cardiovascular and Respiratory therapeutic area.
Principal Scientist, DMPK Merck & Co IncPrincipal Scientist, DMPKBoston, MA$176,200–$277,300 / yearRequired Skills: ADME, Bioanalytical Method Development, Biologics, Cross-Functional Teamwork, DMPK, Drug Metabolism, Immunoassays, Immunology, In Vitro Studies, Mentoring Staff, Oncology, Peptides, Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, Pharmacotherapeutics, PKPD Modeling. The ideal candidate will lead drug metabolism and pharmacokinetic (DMPK) efforts across multiple modalities such as peptides and protein therapeutics as a project-team representative, regularly interacting with multi-disciplinary discovery teams and partners from other functions within our Research & Development Division.
Senior Scientist - Process Modelling SanofiSenior Scientist - Process ModellingFramingham, MA$100.50–$145.17 / hourAs experimental data becomes readily available, the data consumption strategy is taking a central role in the department, with a strong focus on data preparation, data flow and data consumption, feeding applications developed in-house and commercial software used across CMC for data visualization, data modeling and advanced data analytics. About the Job: The global CMC (Chemistry Manufacturing and Control) function is responsible for process development activities in R&D, designing appropriate control strategy to deliver processes of optimum product quality, supplying material for clinical trials and ensuring robust transfer of the process to our commercial organization.
Distinguished Scientist, Companion Diagnostics Merck & Co IncDistinguished Scientist, Companion DiagnosticsBoston, MA$210,400–$331,100 / yearThe Distinguished Scientist/ Executive Director within Companion Diagnostics (CDx) Development, will lead one of our company's Diagnostic Development Teams (DxDTs), supervising PhD-/MD-level employees, developing and overseeing CDx strategy development, alignment and execution for specific projects, including associated digital pathology (DP) projects when applicable. Primary Responsibilities: Lead cross-functional DxDT including Regulatory, Commercial, Business Development, Project Management, Operations, Clinical Development, Statistics, Bioinformatics, etc. to drive CDx strategy, development and implementation of CDx projects - and associated DP when relevant - for a portfolio of various assets/biomarkers, mainly in the therapeutic area of Oncology.
Prin. Scientist, Clinical Research Merck & Co IncPrin. Scientist, Clinical ResearchBoston, MA$190,800–$300,300 / yearInterface broadly with key functions including Discovery Sciences, Preclinical Pharmacology, Pharmaceutical Sciences, Toxicology, Translational Biomarkers, Translational Medicine Operations, Translational Medicine-EU, Drug Metabolism/Modeling & Simulation, Regulatory Affairs, and late-stage Clinical Research throughout research sites around the world. Contributing to the identification of novel targets by partnering with discovery research teams to bring a clinical perspective into the earliest stages of target identification and validation, and executing clinical studies to evaluate the relevance of potential targets to human disease in order to justify investment in clinical development programs.
Senior Scientist, Chemistry (Onsite) Merck & Co IncSenior Scientist, Chemistry (Onsite)Boston, MA$131,400–$206,800 / yearRequired Skills: Analytical Chemistry, Analytical Method Development, Chemical Proteomics, Chemical Synthesis, Chemistry, Chromatography, Laboratory Automation, Laboratory Operations, Mass Spectrometry Based Proteomics, Medicinal Chemistry, Organic Chemistry, Pharmacodynamics, Pharmacokinetics, Process Analytical Technology (PAT), Protein Chromatography. In addition, the candidate will be expected to remain current with the latest synthetic methodologies, drive innovation, apply new concepts to continuously improve group capabilities, and be active in the external scientific community via publications and external presentations.
Senior Data Scientist, Imaging Foundation Models Merck & Co IncSenior Data Scientist, Imaging Foundation ModelsCambridge, MA$144,800–$227,900 / yearPhD in Computer Science, Engineering, Data Science, AI/ML, Bioinformatics, Computational Biology, Genetics & Genomics, Mathematics, Statistics, Physics, Pharmaceutical Science, or related STEM field with 0+ years postdoctoral experience or Master's degree with 4+ years of industry experience. Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities.
NewSr. Scientist, Neuroimmunology Merck & Co IncSr. Scientist, NeuroimmunologyBoston, MA$119,100–$187,500 / yearRequired Skills: Animal Models, Assay Development, Biochemical Assays, Cell Culture Techniques, Flow Cytometry, Immunoassays, Immunology, In Vivo Models, Mouse Handling, Neuroanatomy, Neurodegeneration, Neuroimmunology, Omics, Pharmacodynamics, Transcriptomics. Play a key role in supporting pipeline programs by designing and executing studies, interpreting complex datasets, and communicating findings to cross-functional teams.
Distinguished Scientist, Quantitative Biosciences/ Nonclinical Pharmacology Merck & Co IncDistinguished Scientist, Quantitative Biosciences/ Nonclinical PharmacologyBoston, MA$231,900–$365,000 / yearReporting to the Vice President and Global Head of QB, and partnering closely with discovery scientists across our global Discovery, Preclinical, & Translational Medicine (DPTM) organization, you will leverage your expertise in pharmacology, disease biology, and drug discovery to shape QB and network-wide strategy, guide project teams, and drive cross-functional collaboration. In this role you will: Serve as a scientific integrator, strategic partner, and chief-of-staff to the Vice President/ Global Department Head of Quantitative Biosciences and on the QB leadership team, shaping enterprise pharmacology & translational strategy in alignment with QB and DPTM priorities.
Junior Clinical scientist SanofiJunior Clinical scientistCambridge, MA$122,250–$176,583.33 / yearMain responsibilities: Contributes to preparation and/or review of any documents related to the studies and requiring a scientific background (abbreviated protocol/protocol/amended protocol, patient written information, presentations/communication to internal or external partners, study reports, committee charters, protocol registration form, redacted protocol, lay summary …). Contributes to definition of the centralized monitoring strategy in consistency with the planned statistical analysis and is involved in study data validation and review processes, support the CRD for the Clinical Case review (safety events reported to GPV or safety events of special interest), notably to anticipate and prevent last minute queries or backlog and smoothen the process.
Scientist, Discovery Oncology Merck & Co IncScientist, Discovery OncologyBoston, MA$98,000–$154,300 / yearRequired Skills: Cancer Biology, Cell Death, ELISA Techniques, Flow Cytometry, Immunology, In Vitro Assays, Mammalian Cell Culture, Phenotypic Assays, Primary Cell Culture, T Cell Immunology, T Cell Proliferation Assay. Collaborate with colleagues from Discovery Oncology, Biologics, in vivo pharmacology, Genome, Biomarker Sciences, Chemical Biology, and Quantitative Biosciences to support drug discovery efforts.
Principal Scientist, In Vivo Pharmacology, Oncology Merck & Co IncPrincipal Scientist, In Vivo Pharmacology, OncologyBoston, MA$176,200–$277,300 / yearRequired Skills: Cancer Research, Drug Discovery Process, Immunoassays, Immunohistochemistry (IHC), In Vivo Models, Leading Project Teams, Mass Spectrometry Imaging, Molecular Biology Techniques, Mouse Models, Multiplex Assays, Oncology, Pharmacokinetics, Pharmacology, Tumor Biology. The role will involve building alliances with Discovery Oncology teams at the Boston and South San Francisco sites, championing new technologies (e.g., spatial biology using novel multi-plex immunohistochemistry capabilities), and interfacing with our global pharmacology network.
Crystallization Scientist (Small Molecule) Daley and AssociatesCrystallization Scientist (Small Molecule)Boston, MA$54–$64 / hourOur client, a leading pharmaceutical company focused on discovering, developing, manufacturing, and commercializing therapeutic treatments, is currently seeking a Crystallization Scientist to join its Engineering and Materials Sciences team. This person will support small-molecule drug substance process development at the laboratory and bench scale, with a particular focus on developing API crystallization and particle-forming processes.
Principal Scientist - Formulation Tetraphase Pharmaceuticals IncPrincipal Scientist - FormulationLexington, MANortiva's novel ultra-long-acting oral drug delivery platform uniquely combines elements of controlled drug delivery, traditional and non-traditional formulation components and processes, and dynamic structural features required for gastric residence. Nortiva's drug delivery platform combines traditional and non-traditional formulation processes such as hot-melt-extrusion, coextrusion, injection molding, spray coating, and laser welding.
NewScientist I, Quality Control Replimune Group, Inc.Scientist I, Quality ControlFramingham, MAThe RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The QC Analytical Scientist will be required to assist with scheduling, performing and reviewing of tests results of raw materials, in-process, drug substance and final drug product samples following established test method (SOPs).
Geospatial Data Scientist Mitre CorpGeospatial Data ScientistBedford, MA$124,400–$155,500 / yearApply a variety of spatial data science techniques to tackle customer challenges to include geospatial statistics, spatial optimization, spatial pattern analysis, geospatial artificial intelligence, spatial autocorrelation, activity-based intelligence, imagery analysis, remote sensing, and geospatial data visualization approaches. Department Summary: MITRE's Model-Based Analytics Department (L144) is looking for qualified applicants to bring their geospatial, machine learning, advanced analytics, and applied research skills to bear on solving problems of critical national importance.
Senior Analytical Development Scientist Ratio Therapeutics IncSenior Analytical Development ScientistBoston, MA$145,000–$165,000 / yearPhD in chemistry, pharmaceutical sciences, or a related life sciences field with 5+ years of relevant industry and/or academic experience; MSc with 10+ years or BS with 12+ years of relevant experience Prior experience with radioactive materials such as radiopharmaceuticals and medical isotopes is required. The actual base salary offered will depend on a variety of factors, including qualifications, work experience, skills, level of education attained, certifications or other professional licenses held, the location in which the applicant lives and/or from which they will be performing the job, and other job-related factors permitted by law.
Senior Principal Scientist, Small Molecule Therapeutics Lila Sciences IncSenior Principal Scientist, Small Molecule TherapeuticsCambridge, MAThe ideal candidate is a highly experienced protein scientist and drug discovery leader who can operate strategically while remaining deeply engaged in experimental design, vendor selection, data interpretation, and cross-functional program execution. Oversee recombinant protein expression and purification efforts across external partners and CROs, including vendor selection, scope definition, protocol review, troubleshooting, quality assessment, and timeline management.
HTS Scientist Ginkgo BioWorks IncHTS ScientistBoston, MA$70,800–$106,100 / yearBy leveraging Ginkgo''s state-of-the-art automation and digital infrastructure, Datapoints aims to address the growing demand for high-quality, large-scale biological datasets essential for training AI models in drug discovery and development. Hands-on proficiency operating and troubleshooting common HTS equipment such as the Echo, Prime/Lynx/Hamilton, EL406/Tempest/Combi liquid handlers, and Pherastar readers.
Senior Applications Scientist Bruker CorpSenior Applications ScientistBillerica, MA$101,700–$144,000 / yearIn close cooperation with our customers, Bruker is enabling innovation, improved productivity, and customer success in post-genomic life science molecular and cell biology research, in applied and biopharma applications, in microscopy and nanoanalysis, as well as in industrial and cleantech research, and next-gen semiconductor metrology in support of AI. Bruker offers differentiated, high-value life science and diagnostics systems and solutions in preclinical imaging, clinical phenomics research, proteomics and multiomics, spatial and single-cell biology, functional structural and condensate biology, as well as in clinical microbiology and molecular diagnostics.