Clinical Trial Manager - East Coast HeartFlowClinical Trial Manager - East CoastBoston, MARemote$95,000–$130,000 / yearHeartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMapAnalysis), assess coronary blood flow (FFRCT Analysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). The flagship product-an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFRCT Analysis-provides a color-coded, 3D model of a patient's coronary arteries indicating the impact blockages have on blood flow to the heart.
Clinical Trial Manager - Investigator Initiated Studies HeartFlowClinical Trial Manager - Investigator Initiated StudiesBoston, MA$90,000–$130,000 / yearHeartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMapAnalysis), assess coronary blood flow (FFRCT Analysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). The flagship product-an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFRCT Analysis-provides a color-coded, 3D model of a patient's coronary arteries indicating the impact blockages have on blood flow to the heart.
Lead Clinical Data Manager Karwell TechnologiesLead Clinical Data ManagerCambridge, MACollaborate with cross-functional teams including Biostatistics, Clinical Operations, Safety, and Regulatory to ensure alignment of data management strategies with overall clinical development goals. Develop and implement data management plans, case report forms (CRFs), edit checks, and data validation plans in alignment with study protocols and regulatory requirements.
Clinical Research Coordinator Alcanza Clinical Research LLCClinical Research CoordinatorMAScheduling subjects for study visits and conducts appointment reminders; Building/updating source as needed; Conducting monitoring visits and resolves issues as needed in a timely manner; Ensuring study related reports and patient results are reviewed by investigator in a timely manner; Filing SAE/Deviation reports to Sponsor and IRB as needed; Documenting and reporting adverse events; Reporting non-compliance to appropriate staff in timely manner; Maintaining positive and effective communication with clients and team members; Always practicing ALCOAC principles with all documentation; May assist with study recruitment, patient enrollment, and tracking as needed; Maintaining confidentiality of patients, customers and company information, and; Performing all other duties as requested or assigned. Responsibilities may include but are not limited to: Screening of patients for study enrollment; Patient consents; Patient follow-up visits; Documenting in source clinic charts; Entering data in EDC and answers queries; Obtaining vital signs and ECGs; May perform basic lab procedures per protocol, such as: blood specimen collection, centrifuge operation, storing and shipping of lab specimens, accountability of specimens and notification of courier for specimen pick-up; Requesting and tracking medical record requests; Updating and maintaining logs, chart filings; Maintaining & ordering study specific supplies;].
Clinical Research Coordinator Alcanza Clinical ResearchClinical Research CoordinatorRoslindale, MassachusettsScheduling subjects for study visits and conducts appointment reminders; Building/updating source as needed; Conducting monitoring visits and resolves issues as needed in a timely manner; Ensuring study related reports and patient results are reviewed by investigator in a timely manner; Filing SAE/Deviation reports to Sponsor and IRB as needed; Documenting and reporting adverse events; Reporting non-compliance to appropriate staff in timely manner; Maintaining positive and effective communication with clients and team members; Always practicing ALCOAC principles with all documentation; May assist with study recruitment, patient enrollment, and tracking as needed; Maintaining confidentiality of patients, customers and company information, and; Performing all other duties as requested or assigned. Responsibilities may include but are not limited to: Screening of patients for study enrollment; Patient consents; Patient follow-up visits; Documenting in source clinic charts; Entering data in EDC and answers queries; Obtaining vital signs and ECGs; May perform basic lab procedures per protocol, such as: blood specimen collection, centrifuge operation, storing and shipping of lab specimens, accountability of specimens and notification of courier for specimen pick-up; Requesting and tracking medical record requests; Updating and maintaining logs, chart filings; Maintaining & ordering study specific supplies;].
Senior Program Manager - Medical & Clinical Affairs ConvaTec Group PlcSenior Program Manager - Medical & Clinical AffairsBoston, MARemotePosition Overview: As part of the Project and Portfolio Management team for Medical and Clinical Affairs, the Sr Program Manager oversees the project management, planning, execution, tracking, and reporting of clinical studies and/or research projects in accordance with agreed upon resourcing, timing, and budget. Leader and team-worker who actively looks to develop themself and others; proactively networks across a complex organizational hierarchy and works cooperatively and effectively with others to set goals and resolve problems.
Clinical Research Associate Alira HealthClinical Research AssociateBoston, MassachusettsThe CRA works closely with Lead CRAs, Sr CRAs, in-house CRAs, Associate Director of Clinical Monitoring and Project Managers to ensure protocol compliance, address site questions, and assist with study recruitment, site training, and other site-related issues. The CRA is highly motivated and functions independently to conduct site monitoring responsibilities for clinical trials; as well as providing oversight, leadership, and guidance in the management and execution of clinical trials to ensure compliance and quality.
Clinical Research Associate CRA Alira HealthClinical Research Associate CRABoston, MassachusettsThe CRA works closely with Lead CRAs, Sr CRAs, in-house CRAs, Associate Director of Clinical Monitoring and Project Managers to ensure protocol compliance, address site questions, and assist with study recruitment, site training, and other site-related issues. The CRA is highly motivated and functions independently to conduct site monitoring responsibilities for clinical trials; as well as providing oversight, leadership, and guidance in the management and execution of clinical trials to ensure compliance and quality.
Clinical Study Design Manager Science 37Clinical Study Design ManagerBoston, MAThe following qualifications are preferred and/or equivalent applicable experience: Required: 3+ years of experience in clinical research or life science industry, including at least 3 years in design of CRF/ePRO or other clinical trials database capture software. The Clinical Study Design Manager is responsible for working with our clients and internal staff to define the eSource platform specification design for the study, including all data capture requirements, bridging the gap between protocol requirements and implementation.
Sr. Manager/Associate Director, Clinical Monitoring Oversight Aura Biosciences Inc.Sr. Manager/Associate Director, Clinical Monitoring OversightBoston, MA$150,000–$215,000 / yearThis role is responsible for the strategic oversight of Clinical Research Associates (CRAs) and/or monitoring vendors (CROs), driving site performance, data quality, patient safety, and inspection readiness across all regions in which the trial(s) are conducted. Minimum 7-10 years of clinical research experience, including significant on-site or remote monitoring experience (CRA/Senior CRA background strongly preferred); typically, 3+ years in a lead CRA, monitoring management, or comparable oversight role for AD-level.
Clinical Regulatory Specialist Iterative HealthClinical Regulatory SpecialistCambridge, MAYou will collaborate with site teams, internal stakeholders, sponsors, CROs, IRBs, and other external partners to ensure regulatory requirements are completed accurately, efficiently, and in accordance with applicable guidelines and study requirements. Working under the direction of a Clinical Regulatory Manager Director, you will partner closely with clinical research sites to manage regulatory activities throughout the study lifecycle—from study start-up and activation through ongoing maintenance and closeout.
Manager, Clinical Science Relay Therapeutics, Inc.Manager, Clinical ScienceCambridge, MASupport Medical Lead to monitor real time study data to ensure the integrity of the study and the study data and working closely with clinical operations team to answer protocol related questions and resolve any study conduct issues from investigative sites. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology.
Clinical Trial Associate Candel TherapeuticsClinical Trial AssociateNeedham, MAFull timeThis role includes working on multiple protocols with the potential to cross-train across different oncology indications using a variety of clinical trial databases. Candel is a clinical-stage biopharma company developing off-the-shelf, multimodal immunotherapies that stimulate personalized, systemic anti-tumor responses.
Clinical Trial Manager Skyhawk Therapeutics IncClinical Trial ManagerWaltham, MA$140,000–$200,000 / yearWe use our novel SkySTAR platform (Skyhawk Small molecule Therapeutics for Alternative splicing of RNA) to develop drug candidates directed toward targets for some of the world's most intractable diseases including neurological conditions, cancer, and traditionally "undruggable" targets. Skyhawk Therapeutics seeks an experienced Clinical Trial Manager (title commensurate with experience) who is looking to work in a fast paced, growth mindset organization focused on developing innovative therapies across a broad portfolio of development candidates.
NewClinical Study Operations Manager Beacon BiosignalsClinical Study Operations ManagerBoston, MassachusettsRemote$90,000–$110,000 / yearAs such, we're always seeking new contributors whose work demonstrates an avid curiosity, a bias towards simplicity, an eye for composability, a self-service mindset, and - most of all - a deep empathy towards colleagues, stakeholders, users, and patients. As a Clinical Study Operations Manager within the Clinical Study Operations team, you will be responsible for ensuring the successful operational delivery of Beacon’s clinical studies, from startup through close-out.
Senior Clinical Trial Manager Treeline Biosciences, Inc.Senior Clinical Trial ManagerWatertown, MA$153,000–$197,600 / yearJob responsibilities include, but are not limited to, preparation of study related materials, enrollment tracking and reporting, relationship management with study sites and vendors (in particular CROs), supervision of study-related activities, identification of project risks and contingency planning. Unsolicited resumes sent to Treeline Biosciences from recruiters do not constitute any type of relationship between the recruiter and Treeline Biosciences and do not obligate Treeline Biosciences in any way to pay fees should we hire from those resumes.
Senior Clinical Trial Manager Aditum BioSenior Clinical Trial ManagerCambridge, Massachusetts or Oakland$185,000–$195,000 / yearThe Senior Manager, Clinical Operations will play a key role in the planning, execution, and oversight of early-stage clinical trials across assigned Aditum Bio portfolio companies. This is a hands-on role that requires strong operational execution, vendor oversight, and the ability to thrive in a fast-paced, lean biotech incubator environment supporting multiple portfolio companies.
Director/Sr. Director, Clinical Operations - Oncology Programs Frontier MedicinesDirector/Sr. Director, Clinical Operations - Oncology ProgramsBoston, MA$185,000–$250,000 / yearFrontier Medicines is seeking two experienced Clinical Operations leaders, at the Director or Senior Director level, to drive the operational strategy and execution of our oncology programs as they advance through clinical development. The ideal candidate brings deep oncology experience, strong global study oversight, and the ability to influence stakeholders, anticipate challenges, and deliver results in a dynamic biotech environment.
Clinical Research Coordinator I/Ii/Iii Opportunities - Multiple Locations Nationwide Headlands ResearchClinical Research Coordinator I/Ii/Iii Opportunities - Multiple Locations NationwidePlymouth, MA$45,000–$100,000 / yearThis general interest posting is designed for experienced Clinical Research Coordinators (CRCs) who may not see a current opening that aligns with their location, but want to be considered for future opportunities across our growing network of clinical research sites nationwide. They play a hands-on role in advancing new therapies, supporting patients through clinical trials, and ensuring studies are conducted with the highest level of quality and care.
Director, Late Stage Clinical Development Definium Therapeutics IncDirector, Late Stage Clinical DevelopmentBoston, MA$215,000–$250,000 / yearPartner with the Executive Director Late-Stage Clinical Strategy, Clinical Development, Clinical Operations, HEOR, Medical Affairs, Regulatory Affairs, Commercial, Asset Strategy Lead and Program Leadership to ensure Expanded Access Program and Late-Stage clinical activities are fully integrated into the overall asset strategy. This leader will provide support to ensure programs are scientifically sound, operationally feasible, regulator‑ready, and aligned with the integrated asset strategy, including lifecycle management, real‑world evidence generation, and post‑approval commitments.