Senior Computational Scientist – Systems Biology & Next‑Gen Data Engineering CalliereSenior Computational Scientist – Systems Biology & Next‑Gen Data EngineeringUnion City, CaliforniaYou’ll join a tight-knit team of scientists and engineers decoding huge multi‑omic datasets to uncover patterns that actually change patient outcomes. If you’re driven by the idea of building tools that help decode biology at scale and you thrive where data meets diagnostics, this is your stage.
Computational Pathology Scientist LancesoftComputational Pathology ScientistSouth San Francisco, CA$67Within this group, the Digital Pathology team focuses on revolutionizing the analysis of digital histopathology slides by leveraging computational methods to enhance pathological evaluations traditionally performed solely by humans. The role requires close collaboration with pathologists to design and execute image analysis workflows tailored to biological questions, as well as working with computational and data scientists across various departments.
Staff Software Engineer, Machine Learning And Computational Chemistry Eikon Therapeutics, Inc.Staff Software Engineer, Machine Learning And Computational ChemistryMillbrae, CA$200,000–$241,500 / yearAs part of Eikon's diverse team, you will interface with biologists, chemists, microscopists, and optical and automation engineers to design and deploy computational solutions that enable the exploration and quantification of Eikon's high-content datasets. Practical and theoretical understanding of computational chemistry methods including docking, MD (Molecular Dynamics), FEP (Free Energy Perturbation), and retrosynthetic prediction applied to early drug discovery programs.
Staff Software Engineer, Machine Learning and Computational Chemistry Eikon Therapeutics IncStaff Software Engineer, Machine Learning and Computational ChemistryMillbrae, CA$200,000–$241,500 / yearEikon's discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells, thereby unlocking otherwise intractable classes of proteins as drug targets. As part of Eikon's diverse team, you will interface with biologists, chemists, microscopists, and optical and automation engineers to design and deploy computational solutions that enable the exploration and quantification of Eikon's high-content datasets.
Computational Scientist II Compass ConsultingComputational Scientist IISouth San Francisco, CAOur client is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. Collaborate with interdisciplinary and cross-functional teams including biologists, chemists, data scientists, and other stakeholders.
Computational Neuroscientist The Biological Computing Co.Computational NeuroscientistSan Francisco, CaliforniaYour work will sit at the center of TBC’s Algorithm Discovery Platform: identifying where AI models fail, studying how biological neural networks approach related problems and translating what we learn into usable software. Our Algorithm Discovery Platform brings together biology, computational neuroscience, AI research and software engineering to develop new algorithms, architectures and neurally-optimized software for generative video and next-generation AI infrastructure.
Computational Scientist (Biology) AxiomComputational Scientist (Biology)San Francisco, CaliforniaThis creates a compounding loop: deeper customer understanding shapes the data we generate; better data improves frontier models, Axiom’s fine-tuned models, and our agentic infrastructure; stronger models and tooling expand the capabilities we can offer; and those capabilities are forward deployed into pharma's drug discovery workflows, where scientists use them to solve the highest value drug discovery problems. Analyze high-content imaging and transcriptomic data from primary human hepatocytes and multicellular hepatic systems, including phenotypes related to mitochondrial dysfunction, cholestasis, lipid accumulation, lysosomal stress, ER stress, cytotoxicity, and cellular morphology.
Computational design of biological experiments for model development InceptiveComputational design of biological experiments for model developmentPalo Alto, CaliforniaOur team brings together vast expertise in molecular biology, machine learning, and software engineering, and we are all working towards becoming antedisciplinary, meaning we deepen the knowledge we have in our area of expertise while also expanding our knowledge of completely new fields. We approach our goals with a Beginner's mind, humbly and with fresh eyes, and aim to become the pioneers of a new discipline rooted in biology as much as in deep learning, whose impact will be realized together with out-of-the-box thinkers in business and entrepreneurship, defying established categorizations.
Scientist/Sr. Scientist, Computational Chemistry General ProximityScientist/Sr. Scientist, Computational ChemistrySan Francisco, MississippiThis person should not be an isolated modeler, but a true project partner who sits with chemistry teams, understands the design problem, proposes molecules, helps interpret data, and contributes tools that make the broader organization faster and smarter. This role will help drive small-molecule drug discovery programs by providing practical modeling support, applying modern computational workflows, and using the cheminformatics and AI-enabled tools that empower medicinal chemists and project teams.
Senior Scientist - Computational Protein Design Amgen Inc.Senior Scientist - Computational Protein DesignSouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
AI Biologist - Function LatchBioAI Biologist - FunctionSan Francisco, CaliforniaWorking with software engineers and biologists, you'll build ground-truth benchmark datasets (drawn from real discovery and development programs) that rigorously test whether agents can perform the critical quantitative reasoning steps that human scientists execute: parsing noisy assay data, inferring mechanism, and predicting functional outcomes. You will contribute to our technical approach for evaluating how AI agents reason through biological function: recovering and interpreting experimental evidence to make informed decisions about binding, stability, immune escape, viral fitness, toxin potency, and protein design.
NewScientist Ii/Senior Scientist, Computational Chemistry, Drug Discovery LILAScientist Ii/Senior Scientist, Computational Chemistry, Drug DiscoverySan Francisco, CA$140,800–$217,800 / yearThis person will bring practical computational chemistry experience in a drug discovery context and will work alongside AI systems to make sure agent-generated optimization plans, compound prioritizations, and modeling workflows are chemically and scientifically sensible. The role spans docking, virtual screening, SAR modeling, molecular property prediction, compound prioritization, medicinal chemistry support, live program support, and, most centrally, the design and supervision of computational chemistry tools for agentic workflows.
Scientist II/Senior Scientist, Computational Chemistry, Drug Discovery Lila Sciences IncScientist II/Senior Scientist, Computational Chemistry, Drug DiscoverySan Francisco, CA$140,800–$217,800 / yearThis person will bring practical computational chemistry experience in a drug discovery context and will work alongside AI systems to make sure agent-generated optimization plans, compound prioritizations, and modeling workflows are chemically and scientifically sensible. The role spans docking, virtual screening, SAR modeling, molecular property prediction, compound prioritization, medicinal chemistry support, live program support, and, most centrally, the design and supervision of computational chemistry tools for agentic workflows.
Quantitative Biologist Arcadia ScienceQuantitative BiologistEmeryville, CA$150,000–$200,000 / yearWe are seeking a Quantitative Biologist to join our Validation team with strong expertise in using computational analyses across modalities and biological scales to extract meaning from complex data, identifying the limits of existing analytical approaches, and developing new ones to address them. Your contributions will be instrumental in validating existing tools at Arcadia, shaping how we design and interpret experiments, identifying potential assets, and building robust analytical infrastructure that scales across the team.
Quantitative Biologist Arcadia Science LLCQuantitative BiologistEmeryville, CA$150,000–$200,000 / yearWe are seeking a Quantitative Biologist to join our Validation team with strong expertise in using computational analyses across modalities and biological scales to extract meaning from complex data, identifying the limits of existing analytical approaches, and developing new ones to address them. Your contributions will be instrumental in validating existing tools at Arcadia, shaping how we design and interpret experiments, identifying potential assets, and building robust analytical infrastructure that scales across the team.
Computational Clinical Scientist II, Clinical Bioinformatics Revolution Medicines, Inc.Computational Clinical Scientist II, Clinical BioinformaticsRedwood City, CA$132,000–$166,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Integrate multiple data sources including circulating tumor DNA, patient enrollment data, molecular profiling (RNA/DNA sequencing outputs), multiplex immunohistochemistry to identify and validate new biomarkers for candidate drugs.
Computational Clinical Scientist II, Clinical Bioinformatics Revolution MedicinesComputational Clinical Scientist II, Clinical BioinformaticsRedwood City, CaliforniaIntegrate multiple data sources including circulating tumor DNA, patient enrollment data, molecular profiling (RNA/DNA sequencing outputs), multiplex immunohistochemistry to identify and validate new biomarkers for candidate drugs. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS.
Computational Clinical Scientist II, Clinical Bioinformatics Revolution Medicines IncComputational Clinical Scientist II, Clinical BioinformaticsRedwood City, CA$132,000–$166,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Integrate multiple data sources including circulating tumor DNA, patient enrollment data, molecular profiling (RNA/DNA sequencing outputs), multiplex immunohistochemistry to identify and validate new biomarkers for candidate drugs.
Senior Computational Development Scientist Veracyte IncSenior Computational Development ScientistSouth San Francisco, CARemote$170,000–$187,000 / hourOur Veracyte Diagnostics Platform delivers high-performing cancer tests that are fueled by broad genomic and clinical data, deep bioinformatic and AI capabilities, and a powerful evidence-generation engine, which ultimately drives durable reimbursement and guideline inclusion for our tests, along with new insights to support continued innovation and pipeline development. This senior, independent scientist position is responsible for contributing to assay concepts, driving analytical development and validation, and partnering closely with wet‑lab, clinical, quality, regulatory, and software teams to deliver robust, clinically actionable MRD diagnostics for multiple indications.
Scientist, Probe Design Bio-TechneScientist, Probe DesignNewark, California$89,300–$146,900 / yearThe Scientist will work within a highly dynamic group to develop and optimize new probe products based on our RNAscope® technology and work closely with our commercial team to identify and support customer needs. Our core RNAscope® technology is the world’s first multiplex fluorescent and chromogenic in situ hybridization platform capable of detecting and quantifying RNA biomarkers in situ at single molecule sensitivity.