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Build strong partnerships with Discovery Research, Clinical Pharmacology, Biotherapeutics Discovery, and other internal and external stakeholders to ensure seamless integration of modeling expertise across our therapeutic areas (e.g., Immunology & Respiratory, Cardio-Renal-Metabolic, and Oncology Discovery Research). You will lead, inspire, and develop the Ridgefield PK/PD modeling team, represent the local Team in a global setting, and collaborate across disciplines to deliver high-quality translational strategies resulting in model-informed human efficacious dose predictions across our portfolio.

YEAR

Description Join Boehringer Ingelheim as Director Preclinical PKPD Modeling and become a key scientific and managerial leader within our global Drug Discovery Sciences (DDS) organization. In this high-impact role, you will set the strategic vision and inspire a high-performing team, driving innovative PKPD (pharmacokinetic/pharmacodynamic) modeling strategies that enable model-informed decision-making early in drug discovery. You will lead, inspire, and develop the Ridgefield PK/PD modeling team, represent the local Team in a global setting, and collaborate across disciplines to deliver high-quality translational strategies resulting in model-informed human efficacious dose predictions across our portfolio. This is an outstanding opportunity for a visionary leader ready to shape the future of translational modeling and make a difference for patients worldwide. As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies´ success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim´s high regard for our employees. Duties & Responsibilities • Provide leadership for the Ridgefield Preclinical PKPD Modeling team, ensuring alignment with global Preclinical PKPD Modelling and DDS objectives. Set clear goals, prioritize resources, and foster a culture of scientific excellence and innovation. • Lead, mentor, and develop a diverse team of up to 5 PKPD Modeling scientists. Foster an open, collaborative, and growth-oriented culture through regular feedback, performance reviews, and career development activities. Recruit, onboard, and develop talent to build a highly innovative and impactful modeling team. • Drive the development and implementation of innovative state-of-the-art PKPD modeling approaches, including empirical, mechanistic, and quantitative systems pharmacology models. Focus on advancing NBEs (new biological entity) and NTMs (new therapeutic modalities) and model-informed translational strategies towards high-quality human efficacious dose predictions. • Represent PK/PD modeling in multidisciplinary drug discovery project teams and the global Preclinical PKPD Modelling Leadership Team. Build strong partnerships with Discovery Research, Clinical Pharmacology, Biotherapeutics Discovery, and other internal and external stakeholders to ensure seamless integration of modeling expertise across our therapeutic areas (e.g., Immunology & Respiratory, Cardio-Renal-Metabolic, and Oncology Discovery Research). • Drive the adoption of new modeling methodologies, technologies, and best practices as part of Discovery Research. Develop translational strategies in close collaboration with global teams. Increase the visibility and impact of preclinical PKPD modeling within Boehringer Ingelheim and the broader scientific community. • Ensure delivery of high-quality PKPD modeling outputs, including study design for preclinical PK, biomarker, and pharmacology studies. Ensure clear communication of results to guide model-informed decision-making in drug discovery and provide a good basis for clinical development teams. • Present research at internal and external scientific meetings, publish in peer-reviewed journals, and represent the department in committees and forums. Ensure compliance with regulations, SOPs, and company policies, maintaining accurate records and demonstrating fiscal responsibility. Requirements • PhD in related field or equivalent area of focus with a minimum of 6 years relevant experience in Pharmacometrics / Preclinical PKPD Modelling in the pharmaceutical industry, regulatory agencies, or academia or • Master’s degree in in related field medicine or equivalent area of focus with a minimum of 8 years relevant experience in Pharmacometrics / Preclinical PKPD Modelling in the pharmaceutical industry, regulatory agencies, or academia or • Professional degree in pharmacy or medicine (e.g., PharmD, MD, Apotheker, Arzt) with a minimum of 7 years relevant experience in Pharmacometrics / Preclinical PKPD Modelling in the pharmaceutical industry, regulatory agencies, or academia. • Minimum of 4 years’ relevant experience in working in drug discovery teams preferred. • Proficiency in applying PMx/PKPD/QSP modeling with impact on decision making. Along with experience with empirical and PBPK modeling for NBEs preferred. Deep knowledge of drug discovery process, MID3, and preferentially regulatory guidelines. • Demonstrated ability to manage projects, influence cross-functional teams, and build effective working relationships. • Proven leadership and people management skills, with first experience of developing and inspiring scientific teams. In depth scientific and strategic knowledge in the field and knowledge of overall drug discovery process. • Ability to inspire and motivate a team and focus their energy on achieving business goals. • Process and performance-oriented, constant drive to develop and implement innovative approaches and processes. • Ability to challenge processes and procedures, propose changes, and perform contributions to problem solving. • Excellent communication skills, with a strong publication and presentation record. Eligibility Requirements • Must be legally authorized to work in the United States without restriction. • Must be willing to take a drug test and post-offer physical (if required). • Must be 18 years of age or older. Compensation Data This position offers a base salary typically between $250,000.00 and $394,000.00 USD. The position may be eligible for a role specific variable or performance based bonus and or other compensation elements. For an overview of our benefits please click here (https://www.boehringer-ingelheim.com/us/careers/benefits-rewards) . All qualified applicants will receive consideration for employment without regard to a person’s actual or perceived race, including natural hairstyles, hair texture and protective hairstyles; color; creed; religion; national origin; age; ancestry; citizenship status, marital status; gender, gender identity or expression; sexual orientation, mental, physical or intellectual disability, veteran status; pregnancy, childbirth or related medical condition; genetic information (including the refusal to submit to genetic testing) or any other class or characteristic protected by applicable law.

Boehringer Ingelheim

Director, Preclinical PKPD Modeling

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Professionals choosing Charlotte Hungerford Hospital enjoy an enviable lifestyle in this strategically located New England region: Prime Geographic Position: Perfectly situated midway between Boston and New York City, offering convenient access to world-class urban amenities while maintaining authentic small-town charm. Located in the heart of Litchfield County, CHH delivers comprehensive care with Level III trauma services, award-winning stroke care, and recognized excellence in gastrointestinal and critical care.

<h4>Overview</h4>Somnia Anesthesia | 100% work-life balance | 8 Weeks PTO, $100K Sign-On | In hospital 50% of time | Remote call (rarely called in), post-call off NW Connecticut | Community Hospital | Dynamic leader | Great comp package | New Grads Welcomed! Somnia Anesthesia, a physician-owned and led anesthesia group, is seeking Anesthesiologists to join our growing team at Charlotte Hungerford Hospital in Torrington, CT.   Compensation & Benefits:<ul><li>Compensation: $620,000 annually with 8 weeks PTO</li><li>$100K Sign-On Bonus </li><li>Health | Dental | Vision | Life | Disability | Malpractice</li><li>401(k) | Flexible spending accounts </li><li>CME - Up to $3,000</li></ul> Practice Environment:<ul><li>Work half the year at the hospital</li><li>1 in 3 weekday remote call for O.R. & OB, rarely called in, post-call day off | In hospital 50% of the time</li><li>12 full weekends a year</li><li>4 ORs + 1 GI + OB  </li><li>109 beds | Community hospital </li><li>4 ORs start 7 am, only 1 late room until 5p daily </li><li>5,100 cases per year </li><li>Case mix: B&B, GEN, Ortho, GI and minimal OB </li><li>Medical direction model supervising 4 CRNAs </li></ul> Qualifications:<ul><li>Active CT license  </li><li>Board certification  </li><li>ACLS | PALS | BLS</li></ul>  To learn more about this opportunity, text or call Alexis Benack at (914) 355-8958, or email abenack@somniainc.com  Somnia Anesthesia maintains a stable, long-standing contract and partnership with Hartford Health and Charlotte Hungerford Hospital. Hospital ProfileCharlotte Hungerford Hospital is a 122-bed accredited acute-care facility with deep roots in northwest Connecticut, serving the community since 1916. Located in the heart of Litchfield County, CHH delivers comprehensive care with Level III trauma services, award-winning stroke care, and recognized excellence in gastrointestinal and critical care. Committed to innovation and teamwork, the hospital partnered with MIT to enhance efficiency, responsiveness, and safety. Its collegial clinical team takes pride in making a meaningful difference in patients’ lives when they need it most. Location HighlightsProfessionals choosing Charlotte Hungerford Hospital enjoy an enviable lifestyle in this strategically located New England region:Prime Geographic Position: Perfectly situated midway between Boston and New York City, offering convenient access to world-class urban amenities while maintaining authentic small-town charmNatural Splendor: Surrounded by the breathtaking Litchfield Hills, pristine lakes, and extensive trail systems for year-round outdoor activitiesCultural Richness: Access to the historic Warner Theatre, vibrant local arts scene, and proximity to world-renowned museums and performance venuesFamily-Friendly Community: Excellent schools, safe neighborhoods, and abundant recreational opportunities make this an ideal setting for raising families About Somnia AnesthesiaSince 1996, Somnia has had a singular focus on anesthesia–investing in clinician professional development so patients can get the best care possible. Refer a Colleague and Be RewardedKnow someone who would be a great fit?  Recommend a colleague and earn a referral bonus of up to $5,000 if they are *hired. *Terms and conditions apply.    Somnia does not discriminate against any person based on race, creed, color, religion, gender, sexual orientation, gender identity/expression, national origin, disability, age, genetic information (including family medical history), veteran status, marital status, pregnancy or related condition, or any other basis protected by law. Somnia is committed to complying with all applicable national, state, and local laws on nondiscrimination and equal opportunity.

Somnia Anesthesia

Anesthesiologist - Full-Time | $620k | 1:3 Weekday Remote OR/OB Call | ACT Model | Charlotte Hungerford Hospital - Torrington, CT

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Director, Preclinical PKPD Modeling Boehringer Ingelheim

Anesthesiologist - Full-Time | $620k | 1:3 Weekday Remote OR/OB Call | ACT Model | Charlotte Hungerford Hospital - Torrington, CT Somnia Anesthesia

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