Associate Director or Director, PBPK & Biopharmaceutics Modeling Kymera Therapeutics IncAssociate Director or Director, PBPK & Biopharmaceutics ModelingWatertown, MA$160,000–$275,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Experience modeling oral molecules with challenging developability profiles, including poorly soluble and/or permeable compounds and beyond-rule-of-five modalities such as targeted protein degraders (preferred).
Director Of Clinical Pharmacology Modeling And Simulation GSK, Plc.Director Of Clinical Pharmacology Modeling And SimulationWaltham, MA$183,150–$305,250 / yearAnimal Models, Artificial Intelligence (AI), Clinical Development, Clinical Pharmacology, Drug Design, Drug Development, Drug Discovery Research, In Vitro Models, In Vitro Research, Medication Safety, Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, Pharmacometrics, Regulatory Compliance. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success.
Model Based Systems Engineer Actalent IncModel Based Systems EngineerWoburn, MA$52–$80 / hourWe are seeking a Model Based Systems Engineer to lead development programs through the Systems Engineering process using Model-Based Systems Engineering (MBSE) approaches that support DoD Digital Engineering goals. If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.
Senior Power System Modelling Engineer Powertech Labs IncSenior Power System Modelling EngineerBoston, MARemoteOur internationally recognized consulting team provides a full range of services, including electromagnetic transient studies, system planning and stability analysis (transient, voltage, frequency, and small-signal), disturbance investigations, interconnection studies, renewable integration (wind and solar), load modeling and validation, and NERC compliance (e.g., TPL, PRC, MOD, CIP). Experiences on site commissioning and testing including regular field work following procedures, data collection using digital DAQ systems, control equipment function and communication troubleshooting, safety training and awareness, considered as an asset.
Senior Power System Modelling Engineer Powertech LabsSenior Power System Modelling EngineerLos Angeles, Seattle, Portland, Boston, Austin, Chicago, Phoenix, Dallas, Las Vegas, Denver, San Jose, San Francisco, San Diego, NYC, Philadelphia, Houston, MAFull timeOur internationally recognized consulting team provides a full range of services, including electromagnetic transient studies, system planning and stability analysis (transient, voltage, frequency, and small-signal), disturbance investigations, interconnection studies, renewable integration (wind and solar), load modeling and validation, and NERC compliance (e.g., TPL, PRC, MOD, CIP). Experiences on site commissioning and testing including regular field work following procedures, data collection using digital DAQ systems, control equipment function and communication troubleshooting, safety training and awareness, considered as an asset.
NewStaff Software Engineer, Model Based Merlin Labs IncStaff Software Engineer, Model BasedBoston, MA$200,000–$265,000 / yearThe Merlin Pilot autonomy system powers a growing range of aircraft and mission profiles and has been proven through hundreds of autonomous flights from Merlin's global flight test facilities, including Kerikeri, New Zealand; Quonset Point, Rhode Island; and soon, Bedford, Massachusetts. Headquartered in Boston, Merlin is expanding its organization to accelerate the development and deployment of its autonomy platform, helping customers solve some of aviation's most pressing challenges, from pilot shortages to improving flight safety.
Senior Product Manager, ML Modeling & Platform KlaviyoSenior Product Manager, ML Modeling & PlatformBoston, MA$136,000–$204,000 / yearIn addition to base salary, our total compensation package may include participation in the company's annual cash bonus plan, variable compensation (OTE) for sales and customer success roles, equity, sign-on payments, and a comprehensive range of health, welfare, and wellbeing benefits based on eligibility. You'll be the only PM on the team, embedded with engineering in Palo Alto, and you'll need to earn credibility by speaking the language - not by knowing how to code, but by knowing enough about distributed training, inference tradeoffs, and ML developer experience to make good calls and ask the right questions.
NewStaff Engineer, World Model Development Merlin Labs IncStaff Engineer, World Model DevelopmentBoston, MA$185,000–$325,000 / yearThe Merlin Pilot autonomy system powers a growing range of aircraft and mission profiles and has been proven through hundreds of autonomous flights from Merlin's global flight test facilities, including Kerikeri, New Zealand; Quonset Point, Rhode Island; and soon, Bedford, Massachusetts. About Merlin: Merlin (NASDAQ: MRLN) is a publicly traded aerospace and defense company building a non-human pilot to deliver full-stack autonomy for any aircraft from takeoff to touchdown.
Senior Director, AIRx DMPK & Modeling Lead 3316 Takeda Development Center AmericasSenior Director, AIRx DMPK & Modeling LeadBoston, Massachusetts$212,000–$333,190 / yearThe AIRx DMPK & Modeling Lead will combine extensive scientific and strategic expertise in DMPK and modeling with the agility to thrive in an externalized, AI-powered operating model — leveraging DMPK and modeling depth and pragmatism to direct and integrate quantitative data and decisions at speed. Responsibilities include directing CRO partners with precision and accountability to generate high-quality, interpretable data that feeds into AI-powered DMTA cycles and connecting experimental biology to translational strategy and clinical outcomes.
Fellow in AI/ML for Scientific Applications, Foundation Models, and AI Systems Harvard UniversityFellow in AI/ML for Scientific Applications, Foundation Models, and AI SystemsCambridge, MABachelor's or master's degree in computer science, statistics, electrical engineering, applied mathematics, computational biology/neurobiology, or a related quantitative field required by the expected start date. Demonstrated ability to use modern AI-assisted and agentic coding tools effectively, such as Claude Code, Codex, or similar systems, in research and development workflows.
Postdoctoral AI Researcher in AI/ML for Foundation Models, Scientific Applications, and AI Systems Harvard UniversityPostdoctoral AI Researcher in AI/ML for Foundation Models, Scientific Applications, and AI SystemsCambridge, MADemonstrated ability to use modern AI-assisted and agentic coding tools effectively, such as Claude Code, Codex, or similar systems, in research and development workflows. These positions are especially well suited to candidates prepared to contribute to advanced research programs in modern AI while continuing to grow as scholars within a collaborative academic environment.
Model-Based Systems Engineering Architect General Dynamics Mission Systems, IncModel-Based Systems Engineering ArchitectDedham, Massachusetts$136,837–$151,803 / yearAs the Model-Based Systems Engineer Architect for Nuclear Command, Control and Communications (NC3), you'll be a member of a cross-functional team responsible for leading the design and development of complex systems using Model-Based Systems Engineering methodologies. Company Overview: General Dynamics Mission Systems (GDMS) engineers a diverse portfolio of high technology solutions, products and services that enable customers to successfully execute missions across all domains of operation.
Sr Model-Based Systems Engineering Architect General Dynamics Mission Systems, IncSr Model-Based Systems Engineering ArchitectDedham, MA$201,709–$223,770 / yearAs the Model-Based Systems Engineer Architect for Nuclear Command, Control and Communications (NC3), you'll be a member of a cross-functional team responsible for leading the design and development of complex systems using Model-Based Systems Engineering methodologies. Bachelor's degree in Systems Engineering, or a related Science, Engineering or Mathematics field, plus a minimum of 10 years of relevant experience; or Master's degree, plus a minimum of 8 years of relevant experience.
Senior Machine Learning Scientist, Foundation Model Merck & Co IncSenior Machine Learning Scientist, Foundation ModelCambridge, MA$144,800–$227,900 / yearYou will be part of a broader, cross-functional team of computational biologists, data scientists, software engineers, and machine learning researchers who strive to identify therapeutic targets and biomarkers. Core to the Data, AI, and Genome Sciences (DAGS) function is an AI/ML-first approach to improving target and biomarker discovery, validation, and selection, and elucidating complex disease mechanisms.
Systems Engineer - RF Integration & Performance Modeling BAE Systems PlcSystems Engineer - RF Integration & Performance ModelingNashua, NH$97,008–$164,914 / yearAbout BAE Systems Electronic Systems BAE Systems, Inc. is the U.S. subsidiary of BAE Systems plc, an international defense, aerospace and security company which delivers a full range of products and services for air, land and naval forces, as well as advanced electronics, security, information technology solutions and customer support services. Our ACES team is seeking a highly motivated systems engineer to support the development of new Electronic Attack (EA) capabilities designed to improve air vehicle survivability by detecting, denying, deceiving, degrading, and disrupting adversary Integrated Air Defenses.
Principal Model-Based Systems Engineer STRPrincipal Model-Based Systems EngineerWoburn, Massachusetts$206,000–$284,000 / yearThe ideal candidate will be well-versed in Systems Engineering techniques, Modeling and Simulation, Digital Engineering/MBSE and be excited about opportunities to mentor more junior staff and help foster growth of subject matter expertise across the organization. In addition to modeling in SysML, the Systems Engineer will be responsible for implementing and guiding teams in the customization and automation techniques offered by Cameo to enable multi-disciplinary programs to comply with DoD Digital Engineering goals.
Art Model Bridgewater State UniversityArt ModelBridgewater, MAOur faculty strives to create an environment in which students can investigate a full range of creative expressions in the studio and classroom and where diverse interests in art production and art history can thrive. The mission of the Art Department at Bridgewater State University is to engage students in the exploration of their individual creative and art historical interests.
Lead Model-Based Systems Engineer STRLead Model-Based Systems EngineerWoburn, Massachusetts$157,000–$224,000 / yearThe Systems Engineer should have experience architecting systems, working across the Systems Engineering Lifecycle, a deep understanding of Systems Engineering principles, reverse engineering techniques, and the ability to work with complex software systems and the utilization of Digital Engineering/MBSE to accomplish program goals. The ideal candidate will be experienced in Systems Engineering processes and techniques, Modeling and Simulation, software-based systems, Digital Engineering/MBSE and be excited about opportunities to grow and be a source of subject matter expertise across the organization.
Senior Model-Based Systems Engineer STRSenior Model-Based Systems EngineerWoburn, Massachusetts$138,000–$190,000 / yearThe Systems Engineer should have experience architecting systems, working across the Systems Engineering Lifecycle, a deep understanding of Systems Engineering principles, reverse engineering techniques, and the ability to work with complex software systems and the utilization of Digital Engineering/MBSE to accomplish program goals. The ideal candidate will be experienced in Systems Engineering processes and techniques, Modeling and Simulation, software-based systems, Digital Engineering/MBSE and be excited about opportunities to grow and be a source of subject matter expertise across the organization.
Model Based Engineering Section Manager BAE Systems PlcModel Based Engineering Section ManagerNashua, NH$149,603–$254,317 / yearAbout BAE Systems Electronic Systems BAE Systems, Inc. is the U.S. subsidiary of BAE Systems plc, an international defense, aerospace and security company which delivers a full range of products and services for air, land and naval forces, as well as advanced electronics, security, information technology solutions and customer support services. Our employees work on the world's most advanced software and electronics - from developing world-class autonomous mission management capabilities to advanced data analytics to support the warfighters and the intelligence community.