Model-Based Systems Engineer (MBSE) GCR Professional ServicesModel-Based Systems Engineer (MBSE)Woburn, Massachusetts$75–$90 / hourContractorRole can be Hybrid, TBD The Systems Engineer should have experience architecting systems, working across the Systems Engineering Lifecycle, and in Digital Engineering/Model-Based Systems Engineering (MBSE) achieving architectural integrity and traceability through requirements analysis, system and software development and production system deployment. The ideal candidate will be well-versed in Systems Engineering techniques, Modeling and Simulation, and Digital Engineering/MBSE and be excited about opportunities to mentor more junior staff and help foster growth of subject matter expertise across the organization.
Senior Director, QSP/ PBPK Modeling Kiniksa PharmaceuticalsSenior Director, QSP/ PBPK ModelingLexington, MassachusettsStrong understanding of drug development, clinical trial design, and regulatory expectations related to pharmacology and pharmacometrics, experience contributing regulatory interactions related to modeling and simulation and proven experience applying modeling approaches to clinical decision making, particularly for early‑stage development programs. The successful candidate will serve as a scientific and strategic leader, partnering cross‑functionally with Research, Translational Medicine, Clinical Pharmacology, Clinical Development, and Regulatory teams to ensure model‑informed decision making across the portfolio.
Staff Software Modeling Engineer ARM LtdStaff Software Modeling EngineerWaltham, MA$198,100–$268,000 / yearAbility to own complex technical problems using good engineering judgment to reason through trade-offs, structure maintainable solutions, handle ambiguity, and apply appropriate software development practices. The modeling team in Arm's Central Engineering Software (CE-SW) division enables customers across domains such as IoT, Client, and Infrastructure to develop and validate software on Arm IP-based systems.
Senior Distinguished Scientist for Transgenic Model and Technology SanofiSenior Distinguished Scientist for Transgenic Model and TechnologyCambridge, MA$178,500–$257,833.33 / yearAs the Global Head of Transgenic Biology, you will ensure our organization remains at the forefront of technical developments in genome engineering, enabling breakthrough discoveries in immunology, immuno-inflammation, rare diseases, neuroscience, and oncology. Deep expertise in developing transgenic animal models, including engineering diverse genetic alleles using CRISPR/Cas9, Cas12, base editors, prime editors, and other advanced genome engineering systems.
Tech Staff Neurocognitive Analysis, Modeling, and Simulation MIT Lincoln LaboratoryTech Staff Neurocognitive Analysis, Modeling, and SimulationLexington, MA$145,200–$170,000 / yearOur core technical competencies include system-level modeling and gap analysis, advanced sensing and signal processing, machine learning and artificial intelligence, computational modeling, hardware and software prototyping, model-based systems engineering, and human data collection in laboratory and field environments. Analysis involves features based on mechanistic neuro-biophysical and neuro-motor computational modeling, neuromorphic (software and hardware) simulations, neural interface (e.g., EEG) technology, and machine learning coupled to brain imaging and neural tracing representations.
Postdoctoral research fellows in generative, multimodal AI, and seismic foundational models Harvard UniversityPostdoctoral research fellows in generative, multimodal AI, and seismic foundational modelsMA$67,600–$80,000 / yearJoin our dynamic research team at Harvard University and spearhead groundbreaking research at the intersection of generative AI, multimodal learning, and Earth sciences. Demonstrated strong research skills, evidenced by high-quality publications in top-tier machine learning/AI conferences and/or leading scientific journals.
Senior Scientist, Advanced Ocular In Vitro Models SanofiSenior Scientist, Advanced Ocular In Vitro ModelsCambridge, MA$100.50–$145.17 / hourIntegrate automation and robotics to scale workflows and improve reproducibility, including developing automated liquid handling protocols, implementing high-throughput imaging and data acquisition systems, and optimizing robotic platforms for multi-step differentiation processes. You will work proactively across multidisciplinary teams, lead ophthalmology drug discovery programs, influence project strategies, and mentor colleagues while driving innovation in disease modeling and therapeutic evaluation.
Principal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting) Novartis AGPrincipal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting)Cambridge, MA$126,000–$234,000 / yearEngage in strategic initiatives within M&S, such as creating platform-level translational modeling strategies to impact across projects and developing modeling workflows (e.g., agentic AI).• Proactively seek opportunities to increase the understanding and adoption of translational modeling among internal partners and expand the impact and visibility of modeling through external collaborations. As part of a truly translational modeling team, you will also work closely with clinical pharmacology and pharmacometrics groups to support clinical programs, applying quantitative systems pharmacology (QSP) and mechanistic PBPK/PD approaches to inform key decisions from early dose optimization through life-cycle management.
Model Based Systems Engineer Actalent IncModel Based Systems EngineerWoburn, MA$52–$80 / hourWe are seeking a Model Based Systems Engineer to lead development programs through the Systems Engineering process using Model-Based Systems Engineering (MBSE) approaches that support DoD Digital Engineering goals. If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.
Postdoctoral AI Researcher in AI/ML for Foundation Models, Scientific Applications, and AI Systems Harvard UniversityPostdoctoral AI Researcher in AI/ML for Foundation Models, Scientific Applications, and AI SystemsCambridge, MADemonstrated ability to use modern AI-assisted and agentic coding tools effectively, such as Claude Code, Codex, or similar systems, in research and development workflows. These positions are especially well suited to candidates prepared to contribute to advanced research programs in modern AI while continuing to grow as scholars within a collaborative academic environment.
Fellow in AI/ML for Scientific Applications, Foundation Models, and AI Systems Harvard UniversityFellow in AI/ML for Scientific Applications, Foundation Models, and AI SystemsCambridge, MABachelor's or master's degree in computer science, statistics, electrical engineering, applied mathematics, computational biology/neurobiology, or a related quantitative field required by the expected start date. Demonstrated ability to use modern AI-assisted and agentic coding tools effectively, such as Claude Code, Codex, or similar systems, in research and development workflows.
Instructional Assistant (Specialized Program-Moderate Learning Model) Danvers Public SchoolsInstructional Assistant (Specialized Program-Moderate Learning Model)Danvers, MAPhysical Demands: Percentage of time spent performing the following tasks: Standing Less than 33% Walking Less than 33% Sitting Less than 33% Visual Observation More than 66% Using Hands More than 66% Reaching with Hands and Arms Less than 33% Climbing or Balancing Less than 33% Stooping, Kneeling, Crouching, or Crawling Less than 33% Talking or Hearing More than 66% Lifting (up to 10 lbs) More than 66% Lifting (up to 25 lbs) Less than 33% Work Environment: Percentage of time spent working in the following conditions: Indoor/outdoor playground areas with climbing features: Less than 33% Outdoor weather conditions: Less than 33% School-based environment: Over 66% Full time benefited employees at the Danvers Public Schools are eligible for a comprehensive benefits package offered through the Town of Danvers. Position Title: Instructional Assistant Department: Special Education Reports To: Assistant Director/Building Principal Job Summary: The Instructional Assistant-Moderate (IA) plays a vital role in supporting students with moderate academic, social, and behavioral needs within a specialized classroom setting.
EW Performance Modeling Systems and Software Engineer BAE Systems PlcEW Performance Modeling Systems and Software EngineerNashua, NHfor description visit the url https://jobs.baesystems.com/global/en/job/BAE1US124803BREXTERNAL/EW-Performance-Modeling-Systems-and-Software-Engineer.
Principal Model-Based Systems Engineer STRPrincipal Model-Based Systems EngineerWoburn, MassachusettsThe ideal candidate will be well-versed in Systems Engineering techniques, Modeling and Simulation, Digital Engineering/MBSE and be excited about opportunities to mentor more junior staff and help foster growth of subject matter expertise across the organization. In addition to modeling in SysML, the Systems Engineer will be responsible for implementing and guiding teams in the customization and automation techniques offered by Cameo to enable multi-disciplinary programs to comply with DoD Digital Engineering goals.
Model Based Logistics/Product Support Engineer BAE SystemsModel Based Logistics/Product Support EngineerNashua, NHRemote$118,095–$200,762 / yearAnd you can, too Seeking an experienced Integrated Logistics/Product Support (ILS/IPS) Engineering SME to fill a key modernization role for product portfolios supporting design, development and/or long-term production and sustainment programs. You would be part of a highly visible trailblazing team of Product Support champions and other SMEs charged with collaborating with project teams and other leaders to contribute to the creation of MBPS training materials and company best practices that help develop and guide our MBPS implementation roadmap.
Machine Learning Research Scientist, Mechanical Intuition in Multimodal Models Toyota Research Institute IncMachine Learning Research Scientist, Mechanical Intuition in Multimodal ModelsCambridge, MA$158,400–$227,700 / yearThe Future Factory team in TRI''s Energy and Materials division focuses on developing cutting-edge tools and methods to accelerate change and increase flexibility and efficiency in Toyota''s product design and manufacturing, to speed the transition to an emissions-free world. As a researcher on the team, you will design and implement learning pipelines from scratch, run experiments to evaluate a wide range of architectural, data, and algorithmic choices, and help shape how we apply modern machine learning to the challenges of robotic assembly.
Pre-Doctoral Fellow: Reinforcement Learning for Large Scale Foundation Model Post-Training Harvard UniversityPre-Doctoral Fellow: Reinforcement Learning for Large Scale Foundation Model Post-TrainingCambridge, MA$50,000–$70,000 / yearSuccessful candidates will be self-motivated, have a strong work ethic, be technically skilled, and have strong oral and written skills. Start dates are flexible, but the positions will be filled as soon as possible and will initially be for 6 months, renewable for an additional 6 months following performance review and funding availability.
Tech Staff Neurocognitive Analysis, Modeling, and Simulation Lincoln LaboratoryTech Staff Neurocognitive Analysis, Modeling, and SimulationLexington, MA$145,200–$170,000 / yearOur core technical competencies include system-level modeling and gap analysis, advanced sensing and signal processing, machine learning and artificial intelligence, computational modeling, hardware and software prototyping, model-based systems engineering, and human data collection in laboratory and field environments. Analysis involves features based on mechanistic neuro-biophysical and neuro-motor computational modeling, neuromorphic (software and hardware) simulations, neural interface (e.g., EEG) technology, and machine learning coupled to brain imaging and neural tracing representations.
Adjunct Instructor in Generative AI and Large Language Models in Analytics Brandeis UniversityAdjunct Instructor in Generative AI and Large Language Models in AnalyticsWaltham, MACourse Logistics and Facilitation: Focuses on the organized and timely rollout of course content, maintaining consistent communication through weekly announcements, and ensuring all instructional activities occur within university-approved digital platforms. Instructor Presence and Engagement: Centers on building an active teaching persona by hosting live introductory sessions, facilitating weekly academic discourse in forums, and maintaining regular availability for student consultation.
Lead Model-Based Systems Engineer STRLead Model-Based Systems EngineerWoburn, MassachusettsThe Systems Engineer should have experience architecting systems, working across the Systems Engineering Lifecycle, a deep understanding of Systems Engineering principles, reverse engineering techniques, and the ability to work with complex software systems and the utilization of Digital Engineering/MBSE to accomplish program goals. The ideal candidate will be experienced in Systems Engineering processes and techniques, Modeling and Simulation, software-based systems, Digital Engineering/MBSE and be excited about opportunities to grow and be a source of subject matter expertise across the organization.
Senior Research Scientist Large Behavior Models Toyota Research Institute IncSenior Research Scientist Large Behavior ModelsCambridge, MA$180,000–$270,000 / yearBackground or familiarity with some of the following motion control and actuation whole-body control reinforcement learning robot teleoperation methods common communication protocols research robotic armssystems visual perception and depth sensors machine learning robotic simulation force and tactile sensing systems haptic interfaces. A consistent track record of impact either via first author research publications at top-tier machine learning or robotics conferences RSS NeuRIPS ICML ICLR CoRL ICRA IROS … or via relevant contributions to successful industry initiatives.
Modeling Lead Oncology SanofiModeling Lead OncologyCambridge, MA$178,500–$257,833.33 / yearDocumented experience having initiated and delivered health economic models (from cost-effectiveness to budget impact models) and tools to support country reimbursement and access in Europe, US and other Asian markets (Australia, Taiwan, Japan etc.). Scientifically responsible for the design and implementation of cost-effectiveness and budget impact models to evaluate the economic impact and value of health care interventions in order to support the market access strategy for SANOFI portfolio.
Lead Data Engineer - Data Transformation (Modeling and Architecture) Capital One Financial CorpLead Data Engineer - Data Transformation (Modeling and Architecture)Cambridge, MA$197,300–$225,100 / yearShare your passion for staying on top of tech trends, experimenting with and learning new technologies, participating in internal & external technology communities, and mentoring other members of the engineering community. Candidates hired to work in other locations will be subject to the pay range associated with that location, and the actual annualized salary amount offered to any candidate at the time of hire will be reflected solely in the candidate's offer letter.
Senior Marketing Specialist - Research Models & Services (REMOTE) Charles River Laboratories International IncSenior Marketing Specialist - Research Models & Services (REMOTE)Wilmington, MARemote$75,000–$95,000 / yearCollaborate across marketing, sales, and subject matter experts to engage and help develop persona-based and account-based marketing campaigns in the various customer segments to nurture new and existing clients. Support monitoring of inbound Leads and routing to BDE team as required; includes leads generated from the Charles River website, events, Maestro, and other platforms (Scientist.com,
NewScientist Advanced Cell Models & Delivery Biology Alnylam Pharmaceuticals IncScientist Advanced Cell Models & Delivery BiologyCambridge, MA$110,400–$165,600 / yearWork collaboratively with internal teams and external partners to establish, optimize, and apply advanced 2D and 3D cellular models, including primary cell systems, co-cultures, organoids, spheroids, and microphysiological systems. Strong hands-on experience with advanced in vitro cellular systems, including primary cells and complex 2D/3D culture models such as organoids, spheroids, co-cultures, tissue slices, or microphysiological systems.
Lead AI Engineer (Vision model customization, VLM) Capital One Financial CorpLead AI Engineer (Vision model customization, VLM)MA$197,300–$225,100 / yearBasic Qualifications: Bachelor's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 4 years of experience developing AI and ML algorithms or technologies, or a Master's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 2 years of experience developing AI and ML algorithms or technologies. In this role, you will: Partner with a cross-functional team of engineers, research scientists, technical program managers, and product managers to deliver AI-powered products that change how our associates work and how our customers interact with Capital One.
Model Based Senior Systems Engineer Mitre CorpModel Based Senior Systems EngineerBedford, MA$121,200–$151,500 / yearApplying modern methods and tools such as Model-Based Systems Engineering, Digital Engineering, Mission Engineering, Machine Learning, and Data Analytics to assess capability needs, requirements, architectures, designs, performance constraints and gaps, proposed changes, and verification and test approaches. Bachelor's degree in Engineering, Physics, Mathematics, Systems Engineering, Computer Engineering, Computer Science, or related technical discipline, or equivalent combination of related education and work experience.
Model Based Logistics/Product Support Engineer BAE Systems PlcModel Based Logistics/Product Support EngineerNashua, NHfor description visit the url https://jobs.baesystems.com/global/en/job/BAE1US126121BREXTERNAL/Model-Based-Logistics/Product-Support-Engineer.
Model Based Systems Engineer BAE Systems PlcModel Based Systems EngineerNashua, NHfor description visit the url https://jobs.baesystems.com/global/en/job/BAE1US123455BREXTERNAL/Model-Based-Systems-Engineer.
Principal Model Based Systems Engineer BAE Systems PlcPrincipal Model Based Systems EngineerNashua, NHfor description visit the url https://jobs.baesystems.com/global/en/job/BAE1US123231BREXTERNAL/Principal-Model-Based-Systems-Engineer
Senior Principal Model Based Systems Engineer BAE Systems PlcSenior Principal Model Based Systems EngineerMerrimack, NHfor description visit the url https://jobs.baesystems.com/global/en/job/BAE1US123314BREXTERNAL/Senior-Principal-Model-Based-Systems-Engineer.
NewModel Based Engineering Section Manager BAE Systems PlcModel Based Engineering Section ManagerHudson, NHfor description visit the url https://jobs.baesystems.com/global/en/job/BAE1US126600BREXTERNAL/Model-Based-Engineering-Section-Manager .
Sr. Principal Digital Engineering Model Governance Lead The Charles Stark Draper Laboratory IncSr. Principal Digital Engineering Model Governance LeadCambridge, MA$100,000–$275,000 / yearSimulation applications range from high-level behavioral simulations for visualization and evaluation of system concepts to high-fidelity real-time simulations and Hardware-in-the-Loop infrastructure to support development, integration, test, and sustainment of systems and software. Draper supports many programs to improve work-life balance including workplace flexibility, employee clubs ranging from photography to yoga, health and finance workshops, off site social events and discounts to local museums and cultural activities.
Senior Model-Based Systems Engineer The Charles Stark Draper LaboratorySenior Model-Based Systems EngineerCambridge, MassachusettsThe Systems Concepts Engineer (SMTS) is responsible for the elucidation of mission needs, mission engineering, architecture/design trade space exploration for integrated hardware/software systems, simulation-based performance analysis for complex systems and system-of-systems, architecture definition using digital engineering (DE) and/or model-based system engineering (MBSE) frameworks, briefing of results to leadership or government sponsors, and development of research and development (R&D) proposals. Draper supports many programs to improve work-life balance including workplace flexibility, employee clubs ranging from photography to yoga, health and finance workshops, off site social events and discounts to local museums and cultural activities.
Model-Based Systems Engineer The Charles Stark Draper Laboratory IncModel-Based Systems EngineerCambridge, MA$75,000–$156,000 / yearJob Description Summary: The Systems Concepts Engineer 2 is responsible for the elucidation of mission needs, mission engineering, architecture/design trade space exploration for integrated hardware/software systems, simulation-based performance analysis for complex systems and system-of-systems, architecture definition using digital engineering (DE) and/or model-based system engineering (MBSE) frameworks, briefing of results to leadership or government sponsors, and development of research and development (R&D) proposals. Draper supports many programs to improve work-life balance including workplace flexibility, employee clubs ranging from photography to yoga, health and finance workshops, off site social events and discounts to local museums and cultural activities.
Principal Digital Engineering Model Governance Lead The Charles Stark Draper LaboratoryPrincipal Digital Engineering Model Governance LeadCambridge, MassachusettsSimulation applications range from high-level behavioral simulations for visualization and evaluation of system concepts to high-fidelity real-time simulations and Hardware-in-the-Loop infrastructure to support development, integration, test, and sustainment of systems and software. Draper supports many programs to improve work-life balance including workplace flexibility, employee clubs ranging from photography to yoga, health and finance workshops, off site social events and discounts to local museums and cultural activities.
Systems Modeling, Simulation and Analysis Engineer Connexion Systems + EngineeringSystems Modeling, Simulation and Analysis EngineerWaltham, MA$70–$95 / hourSeeking a Systems Modeling, Simulation, and Analysis Engineer to support the continued development and enhancement of existing MATLAB-based modeling tools. The engineer will work closely with cross-functional teams to understand evolving requirements, implement new modeling capabilities, and support analytical efforts.
Systems Modeling, Simulation & Analysis Engineer Judit IncSystems Modeling, Simulation & Analysis EngineerLexington, MAResponsibilities include but not limited to: Independently adding features and capabilities to the existing Matlab codebase, including the technical background to accurately model basic physics phenomenology in terms of RF propagation, electronic warfare, missile flyouts, sensors etc. Performing quality control on new features and the existing code base to include adding unit tests, and other capabilities to ensure that the results are accurate and that new features are interacting appropriately with the rest of the codebase.
Director, Modeling & Simulation Novartis AGDirector, Modeling & SimulationCambridge, MA$176,400–$327,600 / yearEstablished credibility in the M&S or quantitative pharmacology community (e.g., publications, collaborations, or scientific leadership).Fluency in English (oral and written).This is a hybrid role that requires a balance of in-person and virtual working, with an average of 12 days a month on site in Cambridge, MA.The salary for this position is expected to range between:Director: $176,400 and $327,600 per year. D. in biology, bioengineering, pharmaceutical sciences, biophysics, or a related field.10+ years of relevant postdoctoral, academic, industry, or government experience with a track record as a leader and individual contributor in one or more of the following fields: Disease Modeling, Pathway Modeling, Quantitative Pharmacology, Systems Pharmacology, Mechanistic Modeling.
Systems Modeling, Simulation and Analysis Engineer AthariSystems Modeling, Simulation and Analysis EngineerLexington, MAPerforming modeling runs needed for analysis and building tools that allow for efficient. Responsibilities include but not limited to: Independently adding features and capabilities to the existing Matlab codebase, including.
Modeling & Simulation Engineer II/III Textron IncModeling & Simulation Engineer II/IIIWilmington, MA$92,600–$139,600 / yearBenefits may include health insurance and prescription plan coverage, dental insurance, family building benefits, vision insurance, mental health resources, flexible spending accounts, health savings accounts, retirement savings plans, life and disability insurance programs, and programs that provide employees time away from work. Recruiting Company: Textron Systems Primary Location: US-Massachusetts-Wilmington Job Function: Engineering Schedule: Full-time Job Level: Individual Contributor Job Type: Experienced Shift: First Shift Travel: Yes, 10 % of the Time Job Posting: 04/28/2026, 11:43:01 AM Job Number: 341522.
Principal Modeling Engineer MACOM Technology Solutions Holdings IncPrincipal Modeling EngineerLowell, MAThe individual will be responsible for developing Process Design Kits (PDK) and device models to assist product design across the breadth of MACOMs product portfolio - GaAs, GaN, and Si based semiconductor ICs and modules. Device test support where needed and software development to automate electrical test for device characterization and model extraction.