Senior Director, QSP/ PBPK Modeling Kiniksa Pharmaceuticals CorpSenior Director, QSP/ PBPK ModelingLexington, MA$281,000–$299,000 / yearStrong understanding of drug development, clinical trial design, and regulatory expectations related to pharmacology and pharmacometrics, experience contributing regulatory interactions related to modeling and simulation and proven experience applying modeling approaches to clinical decision making, particularly for early‑stage development programs. The successful candidate will serve as a scientific and strategic leader, partnering cross‑functionally with Research, Translational Medicine, Clinical Pharmacology, Clinical Development, and Regulatory teams to ensure model‑informed decision making across the portfolio.
Systems Modeling, Simulation & Analysis Engineer Judit IncSystems Modeling, Simulation & Analysis EngineerLexington, MAResponsibilities include but not limited to: Independently adding features and capabilities to the existing Matlab codebase, including the technical background to accurately model basic physics phenomenology in terms of RF propagation, electronic warfare, missile flyouts, sensors etc. Performing quality control on new features and the existing code base to include adding unit tests, and other capabilities to ensure that the results are accurate and that new features are interacting appropriately with the rest of the codebase.
Principal Modeling And Simulation Engineer Berkshire Grey Inc.Principal Modeling And Simulation EngineerBedford, MAIn the role of Principal Modeling and Simulation Engineer, you will lead the development of high-fidelity simulation platforms and digital twins that drive system design, validation, and deployment. This role blends advanced software engineering with modeling and simulation, enabling rapid development, testing, and optimization of complex robotic systems.
Senior Staff Engineer, Modeling and Data Applications 3316 Takeda Development Center AmericasSenior Staff Engineer, Modeling and Data ApplicationsLexington, MassachusettsThe actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. D. degree or a M.S. degree in biochemical engineering/biotechnology, data sciences, predictive modeling or closely related fields with 3+ years (PhD.) or 10+ years (M.S.) of experience in modeling and bioprocess development.
Tech Staff Neurocognitive Analysis, Modeling, and Simulation MIT Lincoln LaboratoryTech Staff Neurocognitive Analysis, Modeling, and SimulationLexington, MA$145,200–$170,000 / yearOur core technical competencies include system-level modeling and gap analysis, advanced sensing and signal processing, machine learning and artificial intelligence, computational modeling, hardware and software prototyping, model-based systems engineering, and human data collection in laboratory and field environments. Analysis involves features based on mechanistic neuro-biophysical and neuro-motor computational modeling, neuromorphic (software and hardware) simulations, neural interface (e.g., EEG) technology, and machine learning coupled to brain imaging and neural tracing representations.
Summer Internship in AI-Driven Materials & Electrical Modeling Engineering I1060H E Ink CorporationSummer Internship in AI-Driven Materials & Electrical Modeling Engineering I1060HBillerica, MA$25–$35 / hourOur culture is built on value commitments to innovation, quality, results, integrity, community, people, and collaboration that fosters a strong employee engagement, teamwork, safety and wellness. About the Position: In this role, you will contribute to the development of next-generation materials for microcapsule coating systems by integrating AI-driven research approaches with physical modeling and experimental validation.
NewSenior Director, Qsp/ Pbpk Modeling Kiniksa PharmaceuticalSenior Director, Qsp/ Pbpk ModelingLexington, MAStrong understanding of drug development, clinical trial design, and regulatory expectations related to pharmacology and pharmacometrics, experience contributing regulatory interactions related to modeling and simulation and proven experience applying modeling approaches to clinical decision making, particularly for early‑stage development programs. The successful candidate will serve as a scientific and strategic leader, partnering cross‑functionally with Research, Translational Medicine, Clinical Pharmacology, Clinical Development, and Regulatory teams to ensure model‑informed decision making across the portfolio.
Group 04-47 | SRP Intern - Power System Modeling | Energy Systems | Summer 2026 (Lexington, MA, US) MIT Lincoln LaboratoryGroup 04-47 | SRP Intern - Power System Modeling | Energy Systems | Summer 2026 (Lexington, MA, US)Lexington, MAThis includes developing advanced architectures and system designs to improve the resilience of power grids, developing new control techniques for microgrids and distributed energy resources, and developing hardware and real-time simulation testbeds. The candidate will develop power distribution system models to understand how generation sources (both traditional diesel and natural gas-fired as well as renewables), electric vehicles, energy storage, and distribution system configurations can be best design to support reliable power delivery.
Modeling & Simulation Engineer Connexion Systems + EngineeringModeling & Simulation EngineerBedford, MAThis role will involve developing, maintaining, verifying, validating, and executing large-scale modeling and simulation tools used to evaluate aircraft encounters, collision avoidance systems, sensors, tracking systems, pilot response, and aircraft maneuvering. The team performs fast-time, Monte Carlo simulations at large scale , using simulation and statistical analysis to identify failure conditions, evaluate system performance, and provide findings to government sponsors and external collaborators.
Remote Data Modeling Global Channel ManagementRemote Data ModelingWoburn, MassachusettsRemoteWork with IT, Shared Services and cross functional teams to identify, develop and project manage system integrations to ensure program delivers an integrated solution. Partner with business leaders and customers to identify opportunities for data; determine scopes, evaluate requirements, manage implementations, and monitor quality during and post-production.
Principal Modeling and Simulation Engineer Berkshire Grey IncPrincipal Modeling and Simulation EngineerBedford, MAProficient in: Simulation software development and system modeling frameworks Emulate3D or Sim3D (Rockwell Automation) (required) Nividia Omniverse System design and software architecture Asynchronous / concurrent programming Git, Jira, and modern development workflows Linux / Ubuntu environments Code reviews, testing methodologies, and CI/CD practices Software design patterns (modular, scalable, fault-tolerant systems). Demonstrated ability to: Architect and deliver large-scale simulation and software systems Operate autonomously and drive projects from concept to production Define and communicate technical strategy, tradeoffs, and priorities Navigate and contribute to large, complex codebases Apply an MVP mindset while scaling solutions from prototype to production.
Modeling, Simulation and Analysis Systems Engineer BAE Systems PlcModeling, Simulation and Analysis Systems EngineerNashua, NH$149,603–$254,317 / yearAbout BAE Systems Electronic Systems BAE Systems, Inc. is the U.S. subsidiary of BAE Systems plc, an international defense, aerospace and security company which delivers a full range of products and services for air, land and naval forces, as well as advanced electronics, security, information technology solutions and customer support services. We are seeking systems engineers experienced in modeling and simulation environments to develop, build, and work on the world's most advanced electromagnetic spectrum operations systems - detecting, identifying, locating, and countering threats for joint forces and international aircrew.
Mission Modeling and Simulation, Lead Mitre CorpMission Modeling and Simulation, LeadBedford, MA$155,200–$194,000 / yearMITRE Technology and Engineering (MTE) System Engineering Technical Division is seeking an experienced, highly motivated Lead Mission Modeling and Simulation Engineer to support defense mission engineering, system of systems analysis, and decision-support activities for complex operational missions. Experience evaluating kinetic and non-kinetic mission operations, including one or more of the following domains: air, maritime, land, space, cyber, electromagnetic spectrum operations, communications, command and control, fires, logistics, ISR, autonomy, or integrated air and missile defense.
Applied Scientist - Computational Modeling, OMHS SCS Amazon.com IncApplied Scientist - Computational Modeling, OMHS SCSNorth Reading, MAThe Science Software team in the One MHS organization unlocks Material Handling Equipment (MHE) innovation through a multiplicity of disciplines within Artificial Intelligence (AI) and applied science, including Computer Vision (CV), Physics-Informed Neural Networks (PINNs), Optimization, Reinforcement Learning, classical Machine Learning, statistical modeling, and sensing-hardware. It will be your job to frame ambiguous business problems as tractable scientific problems, and to implement novel ML systems, first-principles models, embedded systems prototypes, and performance optimizations in both prototype and production environments.
Principal EW Modeling & Simulation Engineer BAE Systems PlcPrincipal EW Modeling & Simulation EngineerNashua, NH$118,095–$200,762 / yearAbout BAE Systems Electronic Systems BAE Systems, Inc. is the U.S. subsidiary of BAE Systems plc, an international defense, aerospace and security company which delivers a full range of products and services for air, land and naval forces, as well as advanced electronics, security, information technology solutions and customer support services. We welcome all those who have big ideas, crave innovation, and want to develop, build and work on the world's most advanced electromagnetic spectrum operations systems - detecting, locating and countering threats for joint and international aircrew.
Systems Modeling, Simulation And Analysis Engineer AthariSystems Modeling, Simulation And Analysis EngineerLexington, MA$75–$100 / hourPerforming modeling runs needed for analysis and building tools that allow for efficient. Responsibilities include but not limited to: Independently adding features and capabilities to the existing Matlab codebase, including.
Senior Manager, System Modeling & Design Simulation Symbotic IncSenior Manager, System Modeling & Design SimulationWilmington, MA$180,000–$247,500 / yearApplying next-gen technology, high-density storage and machine learning to solve today's complex distribution challenges, Symbotic enables companies to move goods with unmatched speed, agility, accuracy and efficiency. This team develops mathematical models, analytical tools, and simulation frameworks used to evaluate future system designs, optimize performance, and guide strategic engineering decisions.
NewSystems Engineer - RF Integration & Performance Modeling BAE Systems PlcSystems Engineer - RF Integration & Performance ModelingNashua, NH$97,008–$164,914 / yearAbout BAE Systems Electronic Systems BAE Systems, Inc. is the U.S. subsidiary of BAE Systems plc, an international defense, aerospace and security company which delivers a full range of products and services for air, land and naval forces, as well as advanced electronics, security, information technology solutions and customer support services. Our ACES team is seeking a highly motivated systems engineer to support the development of new Electronic Attack (EA) capabilities designed to improve air vehicle survivability by detecting, denying, deceiving, degrading, and disrupting adversary Integrated Air Defenses.
Modeling and Simulation Engineer Abacus TechnologyModeling and Simulation EngineerHanscom AFB, Massachusetts$135,600–$152,000 / yearKnowledge and experience must include reviewing modeling work for compliance with regulations and best practices; developing and maintaining modeling best practices; analyzing complex problems; developing relevant models and constraints to run complex dynamic structural, thermal or other analyses; and reviewing and supporting work to develop appropriate models to solve complex weapon system issues including networking and communications. Apply analysis tools, object models, and analytical techniques to support mission-level analyses, to include the performance of military communication networks, susceptibility to threats (kinetic, EMP, Cyber, etc.), concept alternatives characterization, development planning, and the analysis of new systems, technologies, effectiveness, and lethality.
NewLead Modeling and Simulations Operations Research Analyst Mitre CorpLead Modeling and Simulations Operations Research AnalystBedford, MA$155,200–$194,000 / yearBasic Qualifications: Degree in a relevant field (e.g., Systems Engineering, Operations Research, Computer Science, Mathematics, Physics, Aerospace Engineering) with 8 years of related experience with a Bachelor's degree; or 6 years and a Master's degree; or a PhD with relevant experience who can immediately contribute at this job step; or equivalent combination of related education and work experience. MITRE is a nonprofit systems engineering, applied research, and advanced technology organization that operates federally funded R&D centers to deliver deep technical and systems integration, rapid prototype development, and mission-driven innovation in the public interest.