New Haven, CT30+ days ago
Your responsibilities will include designing and executing in house animal experiments in mice, proposing, planning and coordinating toxicity, pharmacology and efficacy studies at CROs, performing cell culture experiments with lead candidate RNAs to predict in vivo outcomes, and providing in vivo pharmacology and physiology expertise to accelerate development of our tRNA therapeutics. Cloverleaf's approach to drugging tRNA modifying enzymes uses engineered “trojan horse” tRNAs to modulate translation in cancerous cells.