Scientist I Disease Modeling and Mechanism Disease Biology & Pharmacology Astellas Pharma IncScientist I Disease Modeling and Mechanism Disease Biology & PharmacologyCambridge, MAResponsible for design, execution, and analysis of non-clinical biological studies necessary to validate novel therapeutic concepts and modalities of anti-cancer drugs leveraging cutting-edge science and assay technologies independently. This is a biologist position developing anti-cancer drugs, including antibody-drug conjugates (ADCs), multi-specific antibodies or engineered small molecules in collaboration with discovery and program teams.
Principal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting) Novartis AGPrincipal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting)Cambridge, MA$126,000–$234,000 / yearEngage in strategic initiatives within M&S, such as creating platform-level translational modeling strategies to impact across projects and developing modeling workflows (e.g., agentic AI).• Proactively seek opportunities to increase the understanding and adoption of translational modeling among internal partners and expand the impact and visibility of modeling through external collaborations. As part of a truly translational modeling team, you will also work closely with clinical pharmacology and pharmacometrics groups to support clinical programs, applying quantitative systems pharmacology (QSP) and mechanistic PBPK/PD approaches to inform key decisions from early dose optimization through life-cycle management.
Senior Director, AIRx DMPK & Modeling Lead Takeda Pharmaceutical Co LtdSenior Director, AIRx DMPK & Modeling LeadBoston, MA$212,000–$333,190 / yearThe AIRx DMPK & Modeling Lead will combine extensive scientific and strategic expertise in DMPK and modeling with the agility to thrive in an externalized, AI-powered operating model - leveraging DMPK and modeling depth and pragmatism to direct and integrate quantitative data and decisions at speed. Responsibilities include directing CRO partners with precision and accountability to generate high-quality, interpretable data that feeds into AI-powered DMTA cycles and connecting experimental biology to translational strategy and clinical outcomes.
NewSenior Software Engineer II - Modeling And Simulation Mission Solutions Scientific Systems Company, Inc.Senior Software Engineer II - Modeling And Simulation Mission SolutionsBurlington, MA$142,000–$180,000 / yearDesired: Familiarity with AI robotic navigation and decision algorithms – path planning (A*, RRT), schedule optimization (Simulated Annealing, Genetic Algorithms, Tabu Search), distributed coordination algorithms. The Senior Software Engineer II position in AI/Autonomy systems development will emphasize modeling/simulation (M+S) and software testing of complex autonomy systems in operationally realistic scenarios.
Head of Biotherapeutics Data and Modeling Applications 3316 Takeda Development Center AmericasHead of Biotherapeutics Data and Modeling ApplicationsLexington, MassachusettsYou will drive a modeling strategy that produces robust and predictive models of internal platform processes, ensure alignment with quality and regulatory expectations, and bring external industry insights into the technology roadmap to keep our capabilities current and competitive. This role combines leadership of data and modeling teams with responsibility for identifying and deploying data platforms and analytics tools in close collaboration with the digital, data and technology organization (DD&T).
Sr. Data Scientist - Process Modeling AmgenSr. Data Scientist - Process ModelingBoston, MassachusettsIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role you will join the Digital Process and Systems Analysis group within Process Development plays a key role in providing data infrastructure, platforms, and analytics to support engineering teams across our network, ensuring state-of-the-art data insights to drive innovation and efficiency for the commercialization and optimization of Amgen’s pipeline.
Head of Biotherapeutics Data and Modeling Applications Takeda Pharmaceutical Co LtdHead of Biotherapeutics Data and Modeling ApplicationsLexington, MA$177,000–$278,080 / yearYou will drive a modeling strategy that produces robust and predictive models of internal platform processes, ensure alignment with quality and regulatory expectations, and bring external industry insights into the technology roadmap to keep our capabilities current and competitive. This role combines leadership of data and modeling teams with responsibility for identifying and deploying data platforms and analytics tools in close collaboration with the digital, data and technology organization (DD&T).
Senior Machine Learning Scientist I/II, Model-Driven Optimization Generate BiomedicinesSenior Machine Learning Scientist I/II, Model-Driven OptimizationSomerville, Massachusetts$192,000–$265,000 / yearThe ideal candidate combines depth in probabilistic machine learning, Bayesian optimization, active learning, or related approaches with the practical judgment and engineering discipline to turn technical ideas into reliable systems that drive impact. You will join a collaborative, ambitious team working to build a platform for therapeutic protein design that learns continuously from experimental data and turns that learning into new and better therapeutics with real impact.
Machine Learning Research Scientist, Mechanical Intuition In Multimodal Models Toyota Research InstituteMachine Learning Research Scientist, Mechanical Intuition In Multimodal ModelsCambridge, MA$158,400–$227,700 / yearThe Future Factory team in TRI's Energy and Materials division focuses on developing cutting-edge tools and methods to accelerate change and increase flexibility and efficiency in Toyota's product design and manufacturing, to speed the transition to an emissions-free world. As a researcher on the team, you will design and implement learning pipelines from scratch, run experiments to evaluate a wide range of architectural, data, and algorithmic choices, and help shape how we apply modern machine learning to the challenges of robotic assembly.
Machine Learning Research Scientist, Mechanical Intuition in Multimodal Models Toyota Research InstituteMachine Learning Research Scientist, Mechanical Intuition in Multimodal ModelsCambridge, MA$158,400–$227,700 / yearFull timeThe Future Factory team in TRI's Energy and Materials division focuses on developing cutting-edge tools and methods to accelerate change and increase flexibility and efficiency in Toyota's product design and manufacturing, to speed the transition to an emissions-free world. As a researcher on the team, you will design and implement learning pipelines from scratch, run experiments to evaluate a wide range of architectural, data, and algorithmic choices, and help shape how we apply modern machine learning to the challenges of robotic assembly.
Head Of Bermuda Model Development And Onboarding KKR & Co. Inc.Head Of Bermuda Model Development And OnboardingBoston, MA$170,000–$180,000 / yearKKR aims to generate attractive investment returns by following a patient and disciplined investment approach, employing world-class people, and supporting growth in its portfolio companies and communities. Lead the development, enhancement, and maintenance of actuarial models used for Bermuda EBS valuation, working in close partnership with the Bermuda Actuarial team.
Senior Machine Learning Scientist I, Model-Driven Optimization Generate Biomedicines IncSenior Machine Learning Scientist I, Model-Driven OptimizationSomerville, MA$192,000–$265,000 / yearThe ideal candidate combines depth in probabilistic machine learning, Bayesian optimization, active learning, or related approaches with the practical judgment and engineering discipline to turn technical ideas into reliable systems that drive impact. You will join a collaborative, ambitious team working to build a platform for therapeutic protein design that learns continuously from experimental data and turns that learning into new and better therapeutics with real impact.
Senior Model Validation Analyst Verisk Analytics IncSenior Model Validation AnalystBoston, MAWorking closely with scientists, structural engineers, software professionals, and other cross-functional partners, you will shape thoughtful validation strategies, develop creative ways to expand test coverage, and communicate findings that influence model quality across the organization. As a Senior Model Validation Analyst, you will independently evaluate sophisticated scientific, engineering, and financial model components, turning complex data into clear evidence that models are accurate, reliable, and ready to support critical decisions.
NewSenior Consultant - Digital Assets Enterprise Strategy, Risk and Operating Model Design Deloitte Touche Tohmatsu LtdSenior Consultant - Digital Assets Enterprise Strategy, Risk and Operating Model DesignBoston, MA$119,000–$218,300 / yearServe as a subject matter resource for supporting client engagement teams in business and operational model considerations as well as assessing risk of digital asset ecosystems, covering compliance, regulatory, BSA/AML, cyber, operational, blockchain, and financial risks. Successful candidates will demonstrate an aptitude for complex problem-solving and analytical skills and the ability to communicate complex ideas clearly and persuasively across a variety of strategic, operational, technological, and risk management matters.
EY-Parthenon Manager - Valuations and Modelling Ernst & Young Global LtdEY-Parthenon Manager - Valuations and ModellingBoston, MAWith more than 25,000 people in 150 countries, you will join an inclusive and empowering culture that values your uniqueness, prioritizes your wellbeing, and immerses you in the diverse thinking and cross-cultural experiences necessary to help deliver impact to clients across the globe and to help build a better working world. As a Manager within Valuation & Business Modeling, you will likely spend your day to day working on complex financial decisions, collaborating with management on strategic client decisions and acquisitions and regularly creating financial models using data analytics techniques for strategic priorities.
Model Based Systems Engineer Actalent IncModel Based Systems EngineerWoburn, MA$52–$80 / hourWe are seeking a Model Based Systems Engineer to lead development programs through the Systems Engineering process using Model-Based Systems Engineering (MBSE) approaches that support DoD Digital Engineering goals. If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.
Strategy& Strategy Consulting - Business Model Reinvention - Senior Manager PricewaterhouseCoopers LLPStrategy& Strategy Consulting - Business Model Reinvention - Senior ManagerBoston, MA$124,000–$280,000 / yearPwC does not intend to hire experienced or entry level job seekers who will need, now or in the future, PwC sponsorship through the H-1B lottery, except as set forth within the following policy: https://pwc.to/H-1B-Lottery-Policy . At PwC, we recognize that conviction records may have a direct, adverse, and negative relationship to responsibilities such as accessing sensitive company or customer information, handling proprietary assets, or collaborating closely with team members.
Machine Learning Research Scientist, Mechanical Intuition in Multimodal Models Toyota Research Institute IncMachine Learning Research Scientist, Mechanical Intuition in Multimodal ModelsCambridge, MA$158,400–$227,700 / yearThe Future Factory team in TRI''s Energy and Materials division focuses on developing cutting-edge tools and methods to accelerate change and increase flexibility and efficiency in Toyota''s product design and manufacturing, to speed the transition to an emissions-free world. As a researcher on the team, you will design and implement learning pipelines from scratch, run experiments to evaluate a wide range of architectural, data, and algorithmic choices, and help shape how we apply modern machine learning to the challenges of robotic assembly.
Head of Bermuda Model Development and Onboarding KKR & Co IncHead of Bermuda Model Development and OnboardingBoston, MA$170,000–$180,000 / yearKKR aims to generate attractive investment returns by following a patient and disciplined investment approach, employing world-class people, and supporting growth in its portfolio companies and communities. Lead the development, enhancement, and maintenance of actuarial models used for Bermuda EBS valuation, working in close partnership with the Bermuda Actuarial team.
NewStaff Engineer, World Model Development Merlin LabsStaff Engineer, World Model DevelopmentBoston, MA$185,000–$325,000 / yearThe Merlin Pilot autonomy system powers a growing range of aircraft and mission profiles and has been proven through hundreds of autonomous flights from Merlin's global flight test facilities, including Kerikeri, New Zealand; Quonset Point, Rhode Island; and soon, Bedford, Massachusetts. About Merlin: Merlin (NASDAQ: MRLN) is a publicly traded aerospace and defense company building a non-human pilot to deliver full-stack autonomy for any aircraft from takeoff to touchdown.