Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity And Related) Amgen Inc.Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity And Related)Cambridge, MA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
NewSenior Associate Scientist, Cellular Genomics Pfizer IncSenior Associate Scientist, Cellular GenomicsCambridge, MA$68,600–$114,300 / yearExperience with genomics data analysis, quality control, visualization, or reproducible bioinformatic workflows for bulk RNA sequencing, single-cell and single-nucleus RNA sequencing, spatial transcriptomics, targeted sequencing, immune repertoire sequencing, epigenomics assays, or related genomic technologies. Bachelor's degree in Bioinformatics, Computational Biology, Genomics, Systems Biology, Computer Science & Molecular Biology, Data Science with biological applications, Biological Sciences with significant computational biology course work, or a related discipline with 0-3 years of relevant experience.
NewSenior Scientist, Cellular Genomics Pfizer IncSenior Scientist, Cellular GenomicsCambridge, MA$93,600–$156,000 / yearThe role will also include targeted wet-lab genomic contributions, including study design input, sample-processing strategy, assay-quality review, and limited hands-on support for single-cell, sequencing, or spatial workflows when needed to ensure data quality and interpretability. The candidate should be able to connect disease biology, perturbational responses, pharmacology, and translational context into mechanistic interpretations of drug-candidate effects in collaboration with project scientists, wet-lab genomics experts, translational teams, and computational biology partners.
Principal Scientist, Computational Protein Design ModernaTXPrincipal Scientist, Computational Protein DesignCambridge, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. This individual will work in close partnership with structural biology, directed evolution, immunology, translational science, and program teams to advance platform innovation and therapeutic programs across Moderna’s Research and Early Development portfolio.
Senior Scientist, Computational Biotherapeutics Engineering PfizerSenior Scientist, Computational Biotherapeutics EngineeringMassachusettsPhD in biochemistry, computational chemistry, computational biology, machine learning, or a related field with 0 t 3 years of experience OR Master's Degree in biochemistry, computational chemistry, computational biology, machine learning with 7 to 8 years of experience OR BA/BS with 9 to 11 years of experience. Implement advanced cutting-edge AI and machine learning workflows for computational protein design (including fine-tuning protein language models and generative protein design) in HPC or scalable cloud computing environments.
Executive Director, Data & Methods (Data and Computational Sciences) Vertex PharmaceuticalsExecutive Director, Data & Methods (Data and Computational Sciences)Boston, MassachusettsThis leader will set AI and computational strategy that spans the full breadth of modern drug discovery and scientific therapeutic development; and will translate vision into scalable platforms, methods, and tools that serve every modality and measurably speed up discovery and translation, through the development of cutting-edge methods that leverage critical proprietary and public data to drive impact across our global research portfolio. Lead a multidisciplinary organization of scientists, engineers, and managers — building structure, growing other leaders, and driving organizational effectiveness as a leader of leaders.
Executive Director, Data & Methods (Data And Computational Sciences) Vertex Pharmaceuticals, IncExecutive Director, Data & Methods (Data And Computational Sciences)Boston, MA$270,600–$406,000 / yearThis leader will set AI and computational strategy that spans the full breadth of modern drug discovery and scientific therapeutic development; and will translate vision into scalable platforms, methods, and tools that serve every modality and measurably speed up discovery and translation, through the development of cutting-edge methods that leverage critical proprietary and public data to drive impact across our global research portfolio. Lead a multidisciplinary organization of scientists, engineers, and managers - building structure, growing other leaders, and driving organizational effectiveness as a leader of leaders.
Microbiome Computational Scientist Mass General BrighamMicrobiome Computational ScientistBoston, MassachusettsWith recent funding from the Massachusetts Life Sciences Center, the Lab has built a state-of-the-art compute cluster with extensive GPU and CPU nodes, with the objective of making advanced deep learning technologies broadly available to microbiome researchers. Applications will include forecasting microbial population dynamics in the gut, characterizing the impact of spatial structure of the microbiome, predicting impact of the microbiome on host phenotype, tracking infections in human populations, elucidating microbial metabolism, and discovering functions of uncharacterized microbial metabolites and proteins.
Microbiome Computational Scientist Brigham and Women's HospitalMicrobiome Computational ScientistBoston, MA$93,953.60–$136,739.20 / yearWith recent funding from the Massachusetts Life Sciences Center, the Lab has built a state-of-the-art compute cluster with extensive GPU and CPU nodes, with the objective of making advanced deep learning technologies broadly available to microbiome researchers. Applications will include forecasting microbial population dynamics in the gut, characterizing the impact of spatial structure of the microbiome, predicting impact of the microbiome on host phenotype, tracking infections in human populations, elucidating microbial metabolism, and discovering functions of uncharacterized microbial metabolites and proteins.
Computational Scientist, Assay Development Manifold BioComputational Scientist, Assay DevelopmentBoston, MA$118,000–$138,000 / yearManifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems. Using proprietary molecular barcoding technology, we screen hundreds of thousands of protein designs simultaneously in living systems, producing in vivo-validated datasets at a scale no one else can match.
NewComputational Biologist ProximaComputational BiologistBoston, MAProjects may include designing large-scale scientific workflows for mining public and unique in-house data; developing novel systems biology and structural biology computational methods, tools and algorithms; and/or designing, training and fine-tuning best-in-class machine learning models. Successful candidates will work closely with the Computational Chemistry, Machine Learning and Application Engineering teams to tap into the wealth of evolutionary, structural and -omics data to unlock the full potential of unified machine learning representations and large-scale geometric deep learning generative models.
Principal Scientist, Antibody Discovery and Engineering ModernaTXPrincipal Scientist, Antibody Discovery and EngineeringCambridge, MassachusettsThis individual will operate with a high degree of independence, scientific judgment, and cross-functional influence while partnering with antigen design, structural and computational biology, Immuno-oncology and Autoimmune Therapeutics research leadership, project teams, and external CRO partners. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Senior Scientist in ML Methods for Spatial Biology Bristol-Myers Squibb CoSenior Scientist in ML Methods for Spatial BiologyMA$148,210–$179,601 / yearIPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learning-across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
Advanced Process Analytics Scientist Integrated Resources, IncAdvanced Process Analytics ScientistCambridge, MassachusettsContractorThis includes but not limited to developing tools for deeper understanding of the underlying biological phenomena that lead to differences in product quality (e.g., via metabolic flux modeling, proteomics modeling, bio-informatics); develop robust spectral models correlating to valuable metabolites, cell mass, and product quality attributes (e.g., chemometric models for NIR, Raman). To reach that goal, we are exploring the application of state of the art data science and machine learning while leveraging available process knowledge and a wealth of development and manufacturing data to build end to end product quality predictive meta-models.
Machine Learning Engineer - Computational Drug Discovery 5AM VenturesMachine Learning Engineer - Computational Drug DiscoveryWatertown, MAOur team is dedicated to the development of a broad pipeline of small molecules powered by unique chemistry insights to address a wide range of highly unmet clinical needs. The ideal candidate is comfortable operating across disciplines, takes pride in building reliable systems, and appreciates the opportunity to have a direct impact on scientific decision-making.
Associate Scientist / Scientist I, Computational Test Development PrecedeAssociate Scientist / Scientist I, Computational Test DevelopmentBoston, MassachusettsWe are pioneering an advanced, minimally invasive, comprehensive epigenomics platform with the potential to profoundly impact the research and development of new medicines and the use of approved medicines in clinical practice across a number of conditions, including cancer. MSc in computational biology, bioinformatics, biostatistics, or a closely related quantitative field with 3–4 years of industry or post-graduate research experience in a data-intensive biological or biomedical setting, Ph.
Associate Scientist / Scientist I, Computational Test Development Precede Biosciences, Inc.Associate Scientist / Scientist I, Computational Test DevelopmentBoston, MA$110,000–$150,000 / yearWe are pioneering an advanced, minimally invasive, comprehensive epigenomics platform with the potential to profoundly impact the research and development of new medicines and the use of approved medicines in clinical practice across a number of conditions, including cancer. MSc in computational biology, bioinformatics, biostatistics, or a closely related quantitative field with 3-4 years of industry or post-graduate research experience in a data-intensive biological or biomedical setting, Ph.
Data Scientist ModernaTXData ScientistCambridge, MassachusettsSupport and execute on research projects that leverage internal and external assay data to impact teams, processes, and projects in Biological Sciences, RNA Sciences, Chemistry and Delivery Sciences, and Bioinformatics, via data analysis and visualization, algorithm development, machine learning, and experimental design. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Senior Scientist, Computational Biology - Contract Tessera TherapeuticsSenior Scientist, Computational Biology - ContractSomerville, MA$74–$80 / hourHis group supports drug candidate programs through genotoxicity risk assessment, develops computational approaches to study gene writing biology, and builds scalable data and analysis infrastructure to support molecular assay design and knowledge mining. Broad knowledge of genome editing technologies and associated off-target discovery assays (i.e. WGS; targeted sequencing; GUIDE-seq, Digenome-seq discovery / verification; large and small structural variations and translation effects; NGS QC).
Senior Scientist I, Data Science Senda BiosciencesSenior Scientist I, Data ScienceCambridge, MA$130,000–$170,000 / yearAs a key member of the Sail Biomedicines Data Science team, the Senior Scientist I will operate at the interface of platform and program, applying data-driven approaches to champion broad platform efforts and hands-on analysis of preclinical datasets to transform the treatment landscape for autoimmune diseases, and beyond. Join our team and drive the future of programmable eRNATM therapeutics and In Vivo CAR-T therapies- where AI-driven biology, targeted delivery systems and next-generation immunotherapy converge to redefine what's possible for patients.