Principal Scientist - Modeling & Simulation Amgen Inc.Principal Scientist - Modeling & SimulationThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Principal Scientist - Chemical Biology & Proximity-Based Therapeutics Amgen Inc.Principal Scientist - Chemical Biology & Proximity-Based TherapeuticsThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Principal Scientist - Lead Discovery And Targeted Protein Degradation Biochemistry Amgen Inc.Principal Scientist - Lead Discovery And Targeted Protein Degradation BiochemistryThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Sr. Principal Scientist - Project Toxicologist AmgenSr. Principal Scientist - Project ToxicologistThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Senior Principal Scientist Amgen Inc.Senior Principal ScientistThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this role you will mature core toxicology programs to manage patient safety and EHSS risks of Amgen products, including those from drugs, manufacturing materials, primary containers, and drug-delivery device combination products, as they advance from development to commercialization, and post-approval.
Process Development Principal Scientist Amgen Inc.Process Development Principal ScientistThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. The Amgen DPT leader will lead Drug Product Teams as a DPTL and represent the DP function on Product Development Teams to advance late-stage assets through commercial formulation and process development, process characterization, marketing application, and post-launch commercial maintenance.
Principal Scientist - Clinical Pharmacology Modeling And Simulation Amgen Inc.Principal Scientist - Clinical Pharmacology Modeling And SimulationThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Develop integrated clinical pharmacology plans addressing key program questions related to PK, PD, exposure-response, dose and regimen selection, drug-drug interactions, intrinsic and extrinsic factors, special populations, ethnic sensitivity, formulation changes/biopharmaceutics.
Principal Scientist - Immunogenicity Bioanalytical Sciences AmgenPrincipal Scientist - Immunogenicity Bioanalytical SciencesThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Principal Scientist – Chemical Biology & Proximity-Based Therapeutics AmgenPrincipal Scientist – Chemical Biology & Proximity-Based TherapeuticsThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Principal Scientist - Clinical Pharmacology Modeling and Simulation AmgenPrincipal Scientist - Clinical Pharmacology Modeling and SimulationThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Develop integrated clinical pharmacology plans addressing key program questions related to PK, PD, exposure-response, dose and regimen selection, drug-drug interactions, intrinsic and extrinsic factors, special populations, ethnic sensitivity, formulation changes/biopharmaceutics.
Process Development Sr Principal Scientist AmgenProcess Development Sr Principal ScientistThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role, you will lead a team of analytical scientists responsible for developing, transferring, validating, and implementing analytical methods to support late-phase oligonucleotide programs through commercialization.
Principal Scientist – Inflammation Human Data & Computational Biology AmgenPrincipal Scientist – Inflammation Human Data & Computational BiologyThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Principal Scientist – Lead Discovery and Targeted Protein Degradation Biochemistry AmgenPrincipal Scientist – Lead Discovery and Targeted Protein Degradation BiochemistryThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Principal Scientist - Cardiometabolic Disorders AmgenPrincipal Scientist - Cardiometabolic DisordersThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Demonstrated experience developing, optimizing, and applying GPCR-based in vitro pharmacology assays, including functional signaling assays, ligand-binding assays, receptor internalization, -arrestin, cAMP, calcium mobilization, and pathway-selective (biased signaling) analyses.
Process Development Principal Scientist – Drug Product Technologies AmgenProcess Development Principal Scientist – Drug Product TechnologiesThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role you will join the Pre-Pivotal Drug Product Technologies group, which is responsible for early-stage drug product development across diverse modalities, including antibody-drug conjugates (ADCs), oligonucleotides such as siRNAs, monoclonal antibodies, multispecifics, and other complex biologics.
Process Development Principal Scientist - Drug Product Technologies Amgen Inc.Process Development Principal Scientist - Drug Product TechnologiesThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role you will join the Pre-Pivotal Drug Product Technologies group, which is responsible for early-stage drug product development across diverse modalities, including antibody-drug conjugates (ADCs), oligonucleotides such as siRNAs, monoclonal antibodies, multispecifics, and other complex biologics.
Principal Scientist - Inflammation Human Data & Computational Biology Amgen Inc.Principal Scientist - Inflammation Human Data & Computational BiologyThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Principal Software Engineer Guitar Center CompanyPrincipal Software EngineerWestlake Village, CA$150,000–$190,000 / yearFull timeResponsibilities will include, but will not be limited to the following: Systems Architecture & Design: Lead the design of scalable microservices and API-driven architectures that support real-time inventory, Point of Sale (POS), and warehouse management systems. Requirements Gathering & Specification: Partner with Supply Chain and Retail Product Managers to translate complex business workflows into high-availability technical specifications.
Principal Software Engineer (Embedded) Judge GroupPrincipal Software Engineer (Embedded)Moorpark, CA$180,000–$198,000 / yearLeads development of rapid prototyping and conceptual level testing and will require estimating time to develop software and scoping the depth of the development with project/program management to fit timeline and budget constraints. A BS degree in Computer Science/Engineering, Electrical Engineering, Aerospace, Mechanical Engineering or related field is required or equivalent combination of education, training, and experience.
Ednovate, Principal-In-Residence Edgility SearchEdnovate, Principal-In-ResidenceLos Angeles, CA$115,000–$125,000 / yearMission-driven professional passionate about increasing college attainment for historically under-represented students; Social justice champion committed to promoting educational opportunity for all students and families; Entrepreneurial spirit who thrives in a workplace characterized by autonomy, flexibility, transparency and accountability; Collaborative team player who works well with others from diverse backgrounds, uplifts and celebrates our teammates and engages in healthy debate and feedback to get the best results for students and families; Resourceful, persistent learner with a growth mindset, constantly seeking to “find a way or make one” to master your craft and improve results. Bachelor degree, required; 2+ years of K-12 school leadership experience with a strong track record of improving student outcomes in academics, culture, and engagement, required; experience working in charter schools and/or high school, strongly preferred; 2+ years of experience managing and coaching adults towards ambitious results, required; Clear and compelling connection to Los Angeles, preferred; A California Administrative Credential, Single Subject Teaching Credential or Out of State Teaching Credential, preferred.