San Diego, CA30+ days ago
Key Responsibilities: Design, build, and run cell-based GPCR assays to study receptor function and enable screening of agonists/antagonists/modulators (e.g., Ca²? flux, cAMP, IP-One/IP3, ß-arrestin, reporter gene, BRET/FRET-based readouts, SPRM), including assay optimization for robustness, throughput, and reproducibility. Collaborate closely with Data Science and Computational teams to apply in silico drug discovery approaches, including molecular docking, structure-based modeling, and AI/ML-driven prediction methods, in support of GPCR discovery programs.