Principal Scientist - Chemical Biology & Proximity-Based Therapeutics Amgen Inc.Principal Scientist - Chemical Biology & Proximity-Based TherapeuticsThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Principal Scientist – Lead Discovery and Targeted Protein Degradation Biochemistry AmgenPrincipal Scientist – Lead Discovery and Targeted Protein Degradation BiochemistryThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Senior Principal Scientist Amgen Inc.Senior Principal ScientistThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this role you will mature core toxicology programs to manage patient safety and EHSS risks of Amgen products, including those from drugs, manufacturing materials, primary containers, and drug-delivery device combination products, as they advance from development to commercialization, and post-approval.
Principal Scientist - Clinical Pharmacology Modeling And Simulation Amgen Inc.Principal Scientist - Clinical Pharmacology Modeling And SimulationThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Develop integrated clinical pharmacology plans addressing key program questions related to PK, PD, exposure-response, dose and regimen selection, drug-drug interactions, intrinsic and extrinsic factors, special populations, ethnic sensitivity, formulation changes/biopharmaceutics.
Process Development Principal Scientist - Drug Product Technologies Amgen Inc.Process Development Principal Scientist - Drug Product TechnologiesThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role you will join the Pre-Pivotal Drug Product Technologies group, which is responsible for early-stage drug product development across diverse modalities, including antibody-drug conjugates (ADCs), oligonucleotides such as siRNAs, monoclonal antibodies, multispecifics, and other complex biologics.
Principal Scientist - Inflammation Human Data & Computational Biology Amgen Inc.Principal Scientist - Inflammation Human Data & Computational BiologyThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Principal Digital Design Engineer GreenWave RadiosPrincipal Digital Design EngineerIrvine, CA$190,000–$225,000 / yearOur cutting-edge solutions, powered by the Hermes64 RF SoC, are designed to enhance network energy efficiency while dramatically reducing operational expenses, with purpose-built silicon that is the heart of ORAN-based active antenna arrays. You'll own everything from architecture through production—defining features, authoring device specifications, and driving the design flow for high-performance programmable logic with embedded Linux-based wireless communications software.
Ednovate, Principal-In-Residence Edgility SearchEdnovate, Principal-In-ResidenceLos Angeles, CA$115,000–$125,000 / yearMission-driven professional passionate about increasing college attainment for historically under-represented students; Social justice champion committed to promoting educational opportunity for all students and families; Entrepreneurial spirit who thrives in a workplace characterized by autonomy, flexibility, transparency and accountability; Collaborative team player who works well with others from diverse backgrounds, uplifts and celebrates our teammates and engages in healthy debate and feedback to get the best results for students and families; Resourceful, persistent learner with a growth mindset, constantly seeking to “find a way or make one” to master your craft and improve results. Bachelor degree, required; 2+ years of K-12 school leadership experience with a strong track record of improving student outcomes in academics, culture, and engagement, required; experience working in charter schools and/or high school, strongly preferred; 2+ years of experience managing and coaching adults towards ambitious results, required; Clear and compelling connection to Los Angeles, preferred; A California Administrative Credential, Single Subject Teaching Credential or Out of State Teaching Credential, preferred.
Principal CAD Designer CesiumAstroPrincipal CAD DesignerEl Segundo, CA$48.50–$58.35 / hourThe Principal CAD Designer serves as a key technical resource supporting engineering teams through design execution, product data management, engineering change implementation, and continuous improvement of CAD processes and documentation practices. Please Note: To conform with the United States Government Space Technology Export Regulations, the applicant must be a U.S. citizen, lawful permanent resident of the U.S., conditional resident, asylee or refugee (protected individuals as defined by 8 U.S.C. 1324b(a)(3)), or eligible to obtain the required authorizations from the U.S. Department of State.
Principal Power Electronics Engineer Long WallPrincipal Power Electronics EngineerLong Beach, California$168,900–$256,900 / yearYou will have the opportunity to be a key member of a small team of mechanical, fluid, and electrical engineers working to develop innovative deployable launch solutions that enable the rapid deployment of Long Wall launch and test systems. 5+ years of electronic product experience designing hardware from concept through production; strong emphasis on full life cycle development of new hardware products and not small incremental updates to legacy hardware.
Principal Product Manager United Talent AgencyPrincipal Product ManagerBeverly Hills, California$200,000–$250,000 / yearBuild deep partnerships with cross‑functional leaders—including agents, executives, operations, and engineering—to surface needs, align on priorities, and champion a client‑ and creator‑centric product approach. Define and maintain epics, user stories, and acceptance criteria for complex initiatives, enabling effective agile execution and clear alignment across engineering and design teams.
Principal Component Engineer I CesiumAstroPrincipal Component Engineer IEl Segundo, CA$148,500–$199,000 / yearPlease Note: To conform with the United States Government Space Technology Export Regulations, the applicant must be a U.S. citizen, lawful permanent resident of the U.S., conditional resident, asylee or refugee (protected individuals as defined by 8 U.S.C. 1324b(a)(3)), or eligible to obtain the required authorizations from the U.S. Department of State. If you enjoy working in a startup environment and are passionate about developing leading-edge electronics for satellites, spacecraft, and aerospace systems, we would like to hear from you.
Principal Power Electronics Engineer II CesiumAstroPrincipal Power Electronics Engineer IIEl Segundo, CA$217,000–$266,000 / yearDesign elements and responsibilities will include isolated and non-isolated DC-DC converters, maximum power point tracking solar power converters, magnetics design and analysis, system-level power management and distribution design, point-of-load regulators, switching and linear regulators, filters, and stability analysis and measurement. As a principal engineer on the hardware team, you will be responsible for hardware designs from concept through production, including product roadmaps, block diagrams, part selection, schematic design, PCB layout and routing, analysis, manufacturing (working with contract manufacturers), test, qualification, and in-orbit support.
Principal Power Electronics Engineer I CesiumAstroPrincipal Power Electronics Engineer IEl Segundo, CA$148,500–$199,000 / yearIn this position, you will contribute across the entire development lifecycle of next-generation power electronics hardware for satellites and space power systems payloads-from leading the definition of power system architectures and trade studies to detailed circuit design, simulation, printed circuit board (PCB) layout, verification and integration testing, production transition, and manufacturing support. Experience working with electrical power systems and subsystems, including developing power architecture and power requirements, performing trade studies for size, weight, power, and cost optimization (SWAP-C), selecting power converter topologies, and defining power management and control blocks.
Principal Supplier Quality Engineer CesiumAstroPrincipal Supplier Quality EngineerEl Segundo, CA$143,000–$175,000 / yearPlease Note: To conform with the United States Government Space Technology Export Regulations, the applicant must be a U.S. citizen, lawful permanent resident of the U.S., conditional resident, asylee or refugee (protected individuals as defined by 8 U.S.C. 1324b(a)(3)), or eligible to obtain the required authorizations from the U.S. Department of State. Establish and analyze supplier performance metrics including defect rate, nonconformances, on-time delivery, cost of rework/scrap, and supplier corrective action resolution.
Principal, Capital Markets and Strategy Harbinger MotorsPrincipal, Capital Markets and StrategyGarden Grove, California$140,000–$150,000 / yearHarbinger may use your Candidate Personal Data for the purposes of (i) tracking interactions with our recruiting system; (ii) carrying out, analyzing and improving our application and recruitment process, including assessing you and your application and conducting employment, background and reference checks; (iii) establishing an employment relationship or entering into an employment contract with you; (iv) complying with our legal, regulatory and corporate governance obligations; (v) recordkeeping; (vi) ensuring network and information security and preventing fraud; and (vii) as otherwise required or permitted by applicable law. Harbinger may share your Candidate Personal Data with (i) internal personnel who have a need to know such information in order to perform their duties, including individuals on our HR, legal, and finance teams, and the team(s) with the position(s) for which you are applying; (ii) Harbinger affiliates; and (iii) Harbinger’s service providers, including providers of background checks, staffing services, and cloud services.
Principal Communication Systems Engineer I CesiumAstroPrincipal Communication Systems Engineer IEl Segundo, CA$148,500–$199,000 / yearPlease Note: To conform with the United States Government Space Technology Export Regulations, the applicant must be a U.S. citizen, lawful permanent resident of the U.S., conditional resident, asylee or refugee (protected individuals as defined by 8 U.S.C. 1324b(a)(3)), or eligible to obtain the required authorizations from the U.S. Department of State. In this position, you will help develop space architecture concepts, sub-system design, payload design, requirements development, analysis and decomposition, high-level software and hardware system architecture design, concept of operations (CONOPS) development, and risk assessment.
Principal Mechanical Engineer Salient MotionPrincipal Mechanical EngineerTorrance, California$200,000–$230,000 / yearRequirements Architecture: Translate high-level, ambiguous mission needs into actionable functional and operational requirements for complex electromechanical systems, including spacecraft structures, docking and release mechanisms, robotic arm systems, and military-grade ground support hardware. Cross-Functional Leadership: Act as a technical anchor across the organization, guiding integration efforts, supporting multidisciplinary teams through complex system testing, and authoring test plans, procedures, proposals, and associated program documentation.
Senior Full Stack Principal - Irvine, CA - Only W2 - (JK) Central Business SolutionsSenior Full Stack Principal - Irvine, CA - Only W2 - (JK)Irvine, CaliforniaCollaborate with business and technical stakeholders to deliver aviation-specific solutions. Guide development teams and ensure scalable, secure, and high-performance applications.
Principal GNC Engineer, Responsive Space (Top Secret Clearance) Impulse SpacePrincipal GNC Engineer, Responsive Space (Top Secret Clearance)Redondo Beach, CA$230,000–$270,000 / yearThis position requires applicants to be either U.S. Persons (i.e., U.S. citizen, U.S. national, lawful permanent U.S. resident (green card holder), an individual granted asylum in the U.S., or an individual admitted in U.S. refugee status) or persons eligible to obtain an export license from the U.S. Departments of State, Commerce, or other applicable U.S. government agencies. Participate in vehicle-level hardware and software design reviews and trade studies, coordinating GNC needs to cross-discipline teams.