To research these topics, the lab uses a variety of approaches including generating and differentiating patient-derived induced pluripotent stem cells into a variety of neuronal and glial subtypes and forebrain organoids, live cell calcium imaging, microelectrode array, fluorescent microscopy, viral gene delivery for over-expression and knockdown studies both in vitro and in vivo, cell surface proteomics, and RNA sequencing. The lab seeks a highly motivated postdoctoral research fellow to lead studies related to one or more of our exciting research areas including 1) the role of astrocytes in motor neuron pathology in spinal muscular atrophy and 2) mechanisms underlying neural progenitor cell disruption following cytomegalovirus infection.